DCAF8 (DDB1 and CUL4 associated factor 8)
| Gene | |
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
50717 |
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
DDB1 and CUL4 associated factor 8 |
|
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
DCAF8 |
|
Synonyms (NCBI Gene)
Gene synonyms aliases
|
GAN2, H326, WDR42A |
|
Chromosome
Chromosome number
|
1 |
|
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
1q23.2 |
|
Summary
Summary of gene provided in NCBI Entrez Gene.
|
This gene encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular complex. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2009] |
|
SNPs
SNP information provided by dbSNP.
|
|||||||||
|
|||||||||
|
miRNA
miRNA information provided by mirtarbase database.
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|||||||
|
|||||||
| Protein | |||||||||||||||||||||
| UniProt ID | Q5TAQ9 | ||||||||||||||||||||
| Protein name | DDB1- and CUL4-associated factor 8 (WD repeat-containing protein 42A) | ||||||||||||||||||||
| Protein function | May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. | ||||||||||||||||||||
| PDB | 3I8E | ||||||||||||||||||||
| Family and domains |
Pfam
|
||||||||||||||||||||
| Sequence |
|
||||||||||||||||||||
| Sequence length | 597 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
|
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
|||||||
|
|||||||
|
Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
|
||||||||||||||||
|
||||||||||||||||
|
||||||||||||||||