Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	50615
Gene name Gene Name - the full gene name approved by the HGNC.	Interleukin 21 receptor
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	IL21R
Synonyms (NCBI Gene) Gene synonyms aliases	CD360, IMD56, NILR
Chromosome Chromosome number	16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	16p12.1
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the

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SNP ID	Visualize variation	Clinical significance	Consequence
rs52822694	G>A,T	Benign-likely-benign, conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant
rs397514685	G>A,T	Pathogenic	Missense variant, coding sequence variant
rs886037632	TGCCAC>-	Pathogenic	Inframe deletion, coding sequence variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT018475	hsa-miR-335-5p	Microarray	18185580
MIRT019448	hsa-miR-148b-3p	Microarray	17612493
MIRT025813	hsa-miR-7-5p	Microarray	17612493
MIRT142654	hsa-miR-8485	HITS-CLIP	23824327
MIRT142636	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT142638	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT618359	hsa-miR-501-3p	HITS-CLIP	23824327
MIRT618358	hsa-miR-502-3p	HITS-CLIP	23824327
MIRT618357	hsa-miR-8064	HITS-CLIP	23824327
MIRT618359	hsa-miR-501-3p	HITS-CLIP	23824327
MIRT618358	hsa-miR-502-3p	HITS-CLIP	23824327
MIRT142614	hsa-miR-3607-3p	HITS-CLIP	23824327
MIRT142585	hsa-miR-30a-5p	HITS-CLIP	23824327
MIRT142590	hsa-miR-30b-5p	HITS-CLIP	23824327
MIRT142587	hsa-miR-30c-5p	HITS-CLIP	23824327
MIRT142588	hsa-miR-30d-5p	HITS-CLIP	23824327
MIRT142594	hsa-miR-30e-5p	HITS-CLIP	23824327
MIRT142654	hsa-miR-8485	HITS-CLIP	23824327
MIRT142636	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT142638	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT618359	hsa-miR-501-3p	HITS-CLIP	23824327
MIRT618358	hsa-miR-502-3p	HITS-CLIP	23824327
MIRT618357	hsa-miR-8064	HITS-CLIP	23824327
MIRT142626	hsa-miR-4643	HITS-CLIP	23824327
MIRT618359	hsa-miR-501-3p	HITS-CLIP	23824327
MIRT618358	hsa-miR-502-3p	HITS-CLIP	23824327
MIRT618357	hsa-miR-8064	HITS-CLIP	23824327
MIRT142596	hsa-miR-448	HITS-CLIP	23824327
MIRT142654	hsa-miR-8485	HITS-CLIP	23824327
MIRT142626	hsa-miR-4643	HITS-CLIP	23824327
MIRT618359	hsa-miR-501-3p	HITS-CLIP	23824327
MIRT618358	hsa-miR-502-3p	HITS-CLIP	23824327
MIRT618357	hsa-miR-8064	HITS-CLIP	23824327
MIRT142596	hsa-miR-448	HITS-CLIP	23824327
MIRT569041	hsa-miR-6782-3p	PAR-CLIP	20371350
MIRT569040	hsa-miR-483-5p	PAR-CLIP	20371350
MIRT025813	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT569039	hsa-miR-766-5p	PAR-CLIP	20371350
MIRT194972	hsa-miR-7106-5p	PAR-CLIP	20371350
MIRT569038	hsa-miR-6781-5p	PAR-CLIP	20371350
MIRT569037	hsa-miR-3175	PAR-CLIP	20371350
MIRT569036	hsa-miR-1343-5p	PAR-CLIP	20371350
MIRT569035	hsa-miR-939-5p	PAR-CLIP	20371350
MIRT569034	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT569033	hsa-miR-128-1-5p	PAR-CLIP	20371350
MIRT569032	hsa-miR-128-2-5p	PAR-CLIP	20371350
MIRT569031	hsa-miR-2110	PAR-CLIP	20371350
MIRT569030	hsa-miR-6810-5p	PAR-CLIP	20371350
MIRT569029	hsa-miR-3150a-3p	PAR-CLIP	20371350
MIRT569027	hsa-miR-6763-5p	PAR-CLIP	20371350
MIRT569028	hsa-miR-6857-5p	PAR-CLIP	20371350
MIRT569026	hsa-miR-450a-2-3p	PAR-CLIP	20371350
MIRT569025	hsa-miR-4260	PAR-CLIP	20371350
MIRT569024	hsa-miR-5572	PAR-CLIP	20371350
MIRT569023	hsa-miR-4748	PAR-CLIP	20371350
MIRT569041	hsa-miR-6782-3p	PAR-CLIP	20371350
MIRT569040	hsa-miR-483-5p	PAR-CLIP	20371350
MIRT025813	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT569039	hsa-miR-766-5p	PAR-CLIP	20371350
MIRT194972	hsa-miR-7106-5p	PAR-CLIP	20371350
MIRT569038	hsa-miR-6781-5p	PAR-CLIP	20371350
MIRT569037	hsa-miR-3175	PAR-CLIP	20371350
MIRT569036	hsa-miR-1343-5p	PAR-CLIP	20371350
MIRT569035	hsa-miR-939-5p	PAR-CLIP	20371350
MIRT569034	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT569033	hsa-miR-128-1-5p	PAR-CLIP	20371350
MIRT569032	hsa-miR-128-2-5p	PAR-CLIP	20371350
MIRT569031	hsa-miR-2110	PAR-CLIP	20371350
MIRT569030	hsa-miR-6810-5p	PAR-CLIP	20371350
MIRT569029	hsa-miR-3150a-3p	PAR-CLIP	20371350
MIRT569027	hsa-miR-6763-5p	PAR-CLIP	20371350
MIRT569028	hsa-miR-6857-5p	PAR-CLIP	20371350
MIRT569026	hsa-miR-450a-2-3p	PAR-CLIP	20371350
MIRT569025	hsa-miR-4260	PAR-CLIP	20371350
MIRT569024	hsa-miR-5572	PAR-CLIP	20371350
MIRT569023	hsa-miR-4748	PAR-CLIP	20371350
MIRT569041	hsa-miR-6782-3p	PAR-CLIP	20371350
MIRT569040	hsa-miR-483-5p	PAR-CLIP	20371350
MIRT025813	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT569039	hsa-miR-766-5p	PAR-CLIP	20371350
MIRT194972	hsa-miR-7106-5p	PAR-CLIP	20371350
MIRT569038	hsa-miR-6781-5p	PAR-CLIP	20371350
MIRT569037	hsa-miR-3175	PAR-CLIP	20371350
MIRT569036	hsa-miR-1343-5p	PAR-CLIP	20371350
MIRT569035	hsa-miR-939-5p	PAR-CLIP	20371350
MIRT569034	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT569033	hsa-miR-128-1-5p	PAR-CLIP	20371350
MIRT569032	hsa-miR-128-2-5p	PAR-CLIP	20371350
MIRT569031	hsa-miR-2110	PAR-CLIP	20371350
MIRT569030	hsa-miR-6810-5p	PAR-CLIP	20371350
MIRT569029	hsa-miR-3150a-3p	PAR-CLIP	20371350
MIRT569027	hsa-miR-6763-5p	PAR-CLIP	20371350
MIRT569028	hsa-miR-6857-5p	PAR-CLIP	20371350
MIRT569026	hsa-miR-450a-2-3p	PAR-CLIP	20371350
MIRT569025	hsa-miR-4260	PAR-CLIP	20371350
MIRT569024	hsa-miR-5572	PAR-CLIP	20371350
MIRT569023	hsa-miR-4748	PAR-CLIP	20371350
MIRT142585	hsa-miR-30a-5p	HITS-CLIP	22473208
MIRT142590	hsa-miR-30b-5p	HITS-CLIP	22473208
MIRT142587	hsa-miR-30c-5p	HITS-CLIP	22473208
MIRT142588	hsa-miR-30d-5p	HITS-CLIP	22473208
MIRT142594	hsa-miR-30e-5p	HITS-CLIP	22473208
MIRT142585	hsa-miR-30a-5p	Luciferase reporter assay	27006279
MIRT142654	hsa-miR-8485	HITS-CLIP	23824327
MIRT142636	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT142638	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT618359	hsa-miR-501-3p	HITS-CLIP	23824327
MIRT618358	hsa-miR-502-3p	HITS-CLIP	23824327
MIRT618357	hsa-miR-8064	HITS-CLIP	23824327
MIRT618359	hsa-miR-501-3p	HITS-CLIP	23824327
MIRT618358	hsa-miR-502-3p	HITS-CLIP	23824327
MIRT142614	hsa-miR-3607-3p	HITS-CLIP	23824327
MIRT142585	hsa-miR-30a-5p	HITS-CLIP	23824327
MIRT142590	hsa-miR-30b-5p	HITS-CLIP	23824327
MIRT142587	hsa-miR-30c-5p	HITS-CLIP	23824327
MIRT142588	hsa-miR-30d-5p	HITS-CLIP	23824327
MIRT142594	hsa-miR-30e-5p	HITS-CLIP	23824327
MIRT142654	hsa-miR-8485	HITS-CLIP	23824327
MIRT142636	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT142638	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT618359	hsa-miR-501-3p	HITS-CLIP	23824327
MIRT618358	hsa-miR-502-3p	HITS-CLIP	23824327
MIRT618357	hsa-miR-8064	HITS-CLIP	23824327
MIRT142626	hsa-miR-4643	HITS-CLIP	23824327
MIRT618359	hsa-miR-501-3p	HITS-CLIP	23824327
MIRT618358	hsa-miR-502-3p	HITS-CLIP	23824327
MIRT618357	hsa-miR-8064	HITS-CLIP	23824327
MIRT142596	hsa-miR-448	HITS-CLIP	23824327
MIRT142654	hsa-miR-8485	HITS-CLIP	23824327
MIRT142626	hsa-miR-4643	HITS-CLIP	23824327
MIRT618359	hsa-miR-501-3p	HITS-CLIP	23824327
MIRT618358	hsa-miR-502-3p	HITS-CLIP	23824327
MIRT618357	hsa-miR-8064	HITS-CLIP	23824327
MIRT142596	hsa-miR-448	HITS-CLIP	23824327
MIRT569041	hsa-miR-6782-3p	PAR-CLIP	20371350
MIRT569040	hsa-miR-483-5p	PAR-CLIP	20371350
MIRT025813	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT569039	hsa-miR-766-5p	PAR-CLIP	20371350
MIRT194972	hsa-miR-7106-5p	PAR-CLIP	20371350
MIRT569038	hsa-miR-6781-5p	PAR-CLIP	20371350
MIRT569037	hsa-miR-3175	PAR-CLIP	20371350
MIRT569036	hsa-miR-1343-5p	PAR-CLIP	20371350
MIRT569035	hsa-miR-939-5p	PAR-CLIP	20371350
MIRT569034	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT569033	hsa-miR-128-1-5p	PAR-CLIP	20371350
MIRT569032	hsa-miR-128-2-5p	PAR-CLIP	20371350
MIRT569031	hsa-miR-2110	PAR-CLIP	20371350
MIRT569030	hsa-miR-6810-5p	PAR-CLIP	20371350
MIRT569029	hsa-miR-3150a-3p	PAR-CLIP	20371350
MIRT569027	hsa-miR-6763-5p	PAR-CLIP	20371350
MIRT569028	hsa-miR-6857-5p	PAR-CLIP	20371350
MIRT569026	hsa-miR-450a-2-3p	PAR-CLIP	20371350
MIRT569025	hsa-miR-4260	PAR-CLIP	20371350
MIRT569024	hsa-miR-5572	PAR-CLIP	20371350
MIRT569023	hsa-miR-4748	PAR-CLIP	20371350
MIRT569041	hsa-miR-6782-3p	PAR-CLIP	20371350
MIRT569040	hsa-miR-483-5p	PAR-CLIP	20371350
MIRT025813	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT569039	hsa-miR-766-5p	PAR-CLIP	20371350
MIRT194972	hsa-miR-7106-5p	PAR-CLIP	20371350
MIRT569038	hsa-miR-6781-5p	PAR-CLIP	20371350
MIRT569037	hsa-miR-3175	PAR-CLIP	20371350
MIRT569036	hsa-miR-1343-5p	PAR-CLIP	20371350
MIRT569035	hsa-miR-939-5p	PAR-CLIP	20371350
MIRT569034	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT569033	hsa-miR-128-1-5p	PAR-CLIP	20371350
MIRT569032	hsa-miR-128-2-5p	PAR-CLIP	20371350
MIRT569031	hsa-miR-2110	PAR-CLIP	20371350
MIRT569030	hsa-miR-6810-5p	PAR-CLIP	20371350
MIRT569029	hsa-miR-3150a-3p	PAR-CLIP	20371350
MIRT569027	hsa-miR-6763-5p	PAR-CLIP	20371350
MIRT569028	hsa-miR-6857-5p	PAR-CLIP	20371350
MIRT569026	hsa-miR-450a-2-3p	PAR-CLIP	20371350
MIRT569025	hsa-miR-4260	PAR-CLIP	20371350
MIRT569024	hsa-miR-5572	PAR-CLIP	20371350
MIRT569023	hsa-miR-4748	PAR-CLIP	20371350
MIRT569041	hsa-miR-6782-3p	PAR-CLIP	20371350
MIRT569040	hsa-miR-483-5p	PAR-CLIP	20371350
MIRT025813	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT569039	hsa-miR-766-5p	PAR-CLIP	20371350
MIRT194972	hsa-miR-7106-5p	PAR-CLIP	20371350
MIRT569038	hsa-miR-6781-5p	PAR-CLIP	20371350
MIRT569037	hsa-miR-3175	PAR-CLIP	20371350
MIRT569036	hsa-miR-1343-5p	PAR-CLIP	20371350
MIRT569035	hsa-miR-939-5p	PAR-CLIP	20371350
MIRT569034	hsa-miR-6825-5p	PAR-CLIP	20371350
MIRT569033	hsa-miR-128-1-5p	PAR-CLIP	20371350
MIRT569032	hsa-miR-128-2-5p	PAR-CLIP	20371350
MIRT569031	hsa-miR-2110	PAR-CLIP	20371350
MIRT569030	hsa-miR-6810-5p	PAR-CLIP	20371350
MIRT569029	hsa-miR-3150a-3p	PAR-CLIP	20371350
MIRT569027	hsa-miR-6763-5p	PAR-CLIP	20371350
MIRT569028	hsa-miR-6857-5p	PAR-CLIP	20371350
MIRT569026	hsa-miR-450a-2-3p	PAR-CLIP	20371350
MIRT569025	hsa-miR-4260	PAR-CLIP	20371350
MIRT569024	hsa-miR-5572	PAR-CLIP	20371350
MIRT569023	hsa-miR-4748	PAR-CLIP	20371350
MIRT1064518	hsa-miR-1252	CLIP-seq
MIRT1064519	hsa-miR-1286	CLIP-seq
MIRT1064520	hsa-miR-1343	CLIP-seq
MIRT1064521	hsa-miR-217	CLIP-seq
MIRT1064522	hsa-miR-3074-5p	CLIP-seq
MIRT1064523	hsa-miR-3124-3p	CLIP-seq
MIRT1064524	hsa-miR-3160-5p	CLIP-seq
MIRT1064525	hsa-miR-3169	CLIP-seq
MIRT1064526	hsa-miR-3192	CLIP-seq
MIRT1064527	hsa-miR-377	CLIP-seq
MIRT1064528	hsa-miR-3914	CLIP-seq
MIRT1064529	hsa-miR-4257	CLIP-seq
MIRT1064530	hsa-miR-4300	CLIP-seq
MIRT1064531	hsa-miR-4486	CLIP-seq
MIRT1064532	hsa-miR-4649-5p	CLIP-seq
MIRT1064533	hsa-miR-4705	CLIP-seq
MIRT1064534	hsa-miR-661	CLIP-seq
MIRT1064535	hsa-miR-920	CLIP-seq
MIRT1064536	hsa-miR-1184	CLIP-seq
MIRT1064537	hsa-miR-1205	CLIP-seq
MIRT1064538	hsa-miR-1245	CLIP-seq
MIRT1064539	hsa-miR-30a	CLIP-seq
MIRT1064540	hsa-miR-30b	CLIP-seq
MIRT1064541	hsa-miR-30c	CLIP-seq
MIRT1064542	hsa-miR-30d	CLIP-seq
MIRT1064543	hsa-miR-30e	CLIP-seq
MIRT1064544	hsa-miR-3120-5p	CLIP-seq
MIRT1064545	hsa-miR-3155	CLIP-seq
MIRT1064546	hsa-miR-3155b	CLIP-seq
MIRT1064547	hsa-miR-3158-5p	CLIP-seq
MIRT1064548	hsa-miR-3176	CLIP-seq
MIRT1064549	hsa-miR-3663-5p	CLIP-seq
MIRT1064550	hsa-miR-3664-5p	CLIP-seq
MIRT1064551	hsa-miR-3667-3p	CLIP-seq
MIRT1064552	hsa-miR-3672	CLIP-seq
MIRT1064553	hsa-miR-3677-5p	CLIP-seq
MIRT1064554	hsa-miR-371-5p	CLIP-seq
MIRT1064555	hsa-miR-371b-5p	CLIP-seq
MIRT1064556	hsa-miR-3922-3p	CLIP-seq
MIRT1064557	hsa-miR-3937	CLIP-seq
MIRT1064558	hsa-miR-4267	CLIP-seq
MIRT1064559	hsa-miR-4435	CLIP-seq
MIRT1064560	hsa-miR-4522	CLIP-seq
MIRT1064561	hsa-miR-4757-5p	CLIP-seq
MIRT1064562	hsa-miR-484	CLIP-seq
MIRT1064563	hsa-miR-640	CLIP-seq
MIRT1064536	hsa-miR-1184	CLIP-seq
MIRT2015340	hsa-miR-1224-3p	CLIP-seq
MIRT2015341	hsa-miR-1260	CLIP-seq
MIRT2015342	hsa-miR-1260b	CLIP-seq
MIRT2015343	hsa-miR-1280	CLIP-seq
MIRT2015344	hsa-miR-323-5p	CLIP-seq
MIRT2015345	hsa-miR-326	CLIP-seq
MIRT2015346	hsa-miR-330-5p	CLIP-seq
MIRT2015347	hsa-miR-34b	CLIP-seq
MIRT2015348	hsa-miR-3650	CLIP-seq
MIRT1064550	hsa-miR-3664-5p	CLIP-seq
MIRT1064558	hsa-miR-4267	CLIP-seq
MIRT2015349	hsa-miR-4283	CLIP-seq
MIRT2015350	hsa-miR-4489	CLIP-seq
MIRT2015351	hsa-miR-4656	CLIP-seq
MIRT2015352	hsa-miR-4662a-5p	CLIP-seq
MIRT2015353	hsa-miR-4667-5p	CLIP-seq
MIRT2015354	hsa-miR-4676-5p	CLIP-seq
MIRT2015355	hsa-miR-4700-5p	CLIP-seq
MIRT2015356	hsa-miR-4714-5p	CLIP-seq
MIRT2015357	hsa-miR-4738-5p	CLIP-seq
MIRT2015358	hsa-miR-4755-3p	CLIP-seq
MIRT1064561	hsa-miR-4757-5p	CLIP-seq
MIRT2015359	hsa-miR-532-3p	CLIP-seq
MIRT2015360	hsa-miR-550a	CLIP-seq
MIRT2015361	hsa-miR-575	CLIP-seq
MIRT2015362	hsa-miR-637	CLIP-seq
MIRT2015363	hsa-miR-766	CLIP-seq
MIRT2015364	hsa-miR-876-3p	CLIP-seq
MIRT2015340	hsa-miR-1224-3p	CLIP-seq
MIRT2015341	hsa-miR-1260	CLIP-seq
MIRT2015342	hsa-miR-1260b	CLIP-seq
MIRT2015343	hsa-miR-1280	CLIP-seq
MIRT1064521	hsa-miR-217	CLIP-seq
MIRT1064539	hsa-miR-30a	CLIP-seq
MIRT1064540	hsa-miR-30b	CLIP-seq
MIRT1064541	hsa-miR-30c	CLIP-seq
MIRT1064542	hsa-miR-30d	CLIP-seq
MIRT1064543	hsa-miR-30e	CLIP-seq
MIRT1064545	hsa-miR-3155	CLIP-seq
MIRT1064546	hsa-miR-3155b	CLIP-seq
MIRT1064531	hsa-miR-4486	CLIP-seq
MIRT2247674	hsa-miR-455-5p	CLIP-seq
MIRT1064532	hsa-miR-4649-5p	CLIP-seq
MIRT2247675	hsa-miR-4693-3p	CLIP-seq
MIRT2015357	hsa-miR-4738-5p	CLIP-seq
MIRT2247676	hsa-miR-4740-3p	CLIP-seq
MIRT2015358	hsa-miR-4755-3p	CLIP-seq
MIRT1064562	hsa-miR-484	CLIP-seq
MIRT2015359	hsa-miR-532-3p	CLIP-seq
MIRT1064534	hsa-miR-661	CLIP-seq
MIRT2015363	hsa-miR-766	CLIP-seq
MIRT2465490	hsa-miR-4477a	CLIP-seq
MIRT2465491	hsa-miR-498	CLIP-seq
MIRT1064537	hsa-miR-1205	CLIP-seq
MIRT2551107	hsa-miR-122	CLIP-seq
MIRT2551108	hsa-miR-125a-3p	CLIP-seq
MIRT2551109	hsa-miR-130a	CLIP-seq
MIRT2551110	hsa-miR-130b	CLIP-seq
MIRT1064520	hsa-miR-1343	CLIP-seq
MIRT2551111	hsa-miR-149	CLIP-seq
MIRT2551112	hsa-miR-23a	CLIP-seq
MIRT2551113	hsa-miR-23b	CLIP-seq
MIRT2551114	hsa-miR-23c	CLIP-seq
MIRT2551115	hsa-miR-24	CLIP-seq
MIRT2551116	hsa-miR-27a	CLIP-seq
MIRT2551117	hsa-miR-27b	CLIP-seq
MIRT2551118	hsa-miR-301a	CLIP-seq
MIRT2551119	hsa-miR-301b	CLIP-seq
MIRT2551120	hsa-miR-3064-5p	CLIP-seq
MIRT1064522	hsa-miR-3074-5p	CLIP-seq
MIRT1064539	hsa-miR-30a	CLIP-seq
MIRT1064540	hsa-miR-30b	CLIP-seq
MIRT1064541	hsa-miR-30c	CLIP-seq
MIRT1064542	hsa-miR-30d	CLIP-seq
MIRT1064543	hsa-miR-30e	CLIP-seq
MIRT1064544	hsa-miR-3120-5p	CLIP-seq
MIRT1064523	hsa-miR-3124-3p	CLIP-seq
MIRT2551121	hsa-miR-3135b	CLIP-seq
MIRT1064545	hsa-miR-3155	CLIP-seq
MIRT1064546	hsa-miR-3155b	CLIP-seq
MIRT1064524	hsa-miR-3160-5p	CLIP-seq
MIRT1064526	hsa-miR-3192	CLIP-seq
MIRT2015345	hsa-miR-326	CLIP-seq
MIRT2015346	hsa-miR-330-5p	CLIP-seq
MIRT2551122	hsa-miR-3652	CLIP-seq
MIRT1064550	hsa-miR-3664-5p	CLIP-seq
MIRT2551123	hsa-miR-3665	CLIP-seq
MIRT2551124	hsa-miR-3666	CLIP-seq
MIRT1064552	hsa-miR-3672	CLIP-seq
MIRT2551125	hsa-miR-3690	CLIP-seq
MIRT1064554	hsa-miR-371-5p	CLIP-seq
MIRT1064555	hsa-miR-371b-5p	CLIP-seq
MIRT2551126	hsa-miR-3934	CLIP-seq
MIRT2551127	hsa-miR-412	CLIP-seq
MIRT2551128	hsa-miR-4254	CLIP-seq
MIRT1064558	hsa-miR-4267	CLIP-seq
MIRT2551129	hsa-miR-4284	CLIP-seq
MIRT2551130	hsa-miR-4295	CLIP-seq
MIRT1064530	hsa-miR-4300	CLIP-seq
MIRT2551131	hsa-miR-4430	CLIP-seq
MIRT1064560	hsa-miR-4522	CLIP-seq
MIRT2551132	hsa-miR-454	CLIP-seq
MIRT2551133	hsa-miR-4690-3p	CLIP-seq
MIRT2551134	hsa-miR-4711-3p	CLIP-seq
MIRT2551135	hsa-miR-4726-3p	CLIP-seq
MIRT2551136	hsa-miR-4768-3p	CLIP-seq
MIRT2551137	hsa-miR-4786-5p	CLIP-seq
MIRT2551138	hsa-miR-4794	CLIP-seq
MIRT1064562	hsa-miR-484	CLIP-seq
MIRT2551139	hsa-miR-499-3p	CLIP-seq
MIRT2551140	hsa-miR-499a-3p	CLIP-seq
MIRT2551141	hsa-miR-548c-3p	CLIP-seq
MIRT2551142	hsa-miR-552	CLIP-seq
MIRT2551143	hsa-miR-593	CLIP-seq
MIRT2551144	hsa-miR-657	CLIP-seq
MIRT2551145	hsa-miR-663b	CLIP-seq
MIRT2551146	hsa-miR-665	CLIP-seq
MIRT2551147	hsa-miR-891a	CLIP-seq
MIRT1064535	hsa-miR-920	CLIP-seq
MIRT1064520	hsa-miR-1343	CLIP-seq
MIRT1064522	hsa-miR-3074-5p	CLIP-seq
MIRT1064544	hsa-miR-3120-5p	CLIP-seq
MIRT1064523	hsa-miR-3124-3p	CLIP-seq
MIRT1064524	hsa-miR-3160-5p	CLIP-seq
MIRT1064526	hsa-miR-3192	CLIP-seq
MIRT1064550	hsa-miR-3664-5p	CLIP-seq
MIRT1064552	hsa-miR-3672	CLIP-seq
MIRT1064554	hsa-miR-371-5p	CLIP-seq
MIRT1064555	hsa-miR-371b-5p	CLIP-seq
MIRT1064530	hsa-miR-4300	CLIP-seq
MIRT1064560	hsa-miR-4522	CLIP-seq
MIRT2551136	hsa-miR-4768-3p	CLIP-seq
MIRT1064535	hsa-miR-920	CLIP-seq

Show/Hide all(13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001532	Function	Interleukin-21 receptor activity	NAS	11081504
GO:0004888	Function	Transmembrane signaling receptor activity	IDA	11016959
GO:0004896	Function	Cytokine receptor activity	IBA
GO:0004896	Function	Cytokine receptor activity	IDA	11016959
GO:0004896	Function	Cytokine receptor activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005886	Component	Plasma membrane	TAS
GO:0009897	Component	External side of plasma membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	NAS	11081504
GO:0019221	Process	Cytokine-mediated signaling pathway	IBA
GO:0030101	Process	Natural killer cell activation	NAS	11081504
GO:0038114	Process	Interleukin-21-mediated signaling pathway	IEA

MIM	HGNC	e!Ensembl
605383	6006	ENSG00000103522

Protein

UniProt ID

Q9HBE5

Protein name

Interleukin-21 receptor (IL-21 receptor) (IL-21R) (Novel interleukin receptor) (CD antigen CD360)

Protein function

This is a receptor for interleukin-21.

PDB

3TGX , 4NZD , 6PLH , 7KQ7 , 8ENT

Family and domains

Tissue specificity

TISSUE SPECIFICITY: Selectively expressed in lymphoid tissues. Most highly expressed in thymus and spleen.

Sequence

MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD
EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP
APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS
RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL
LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS
LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG
SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD
AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS
PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS

Sequence length

538

Interactions

View interactions

	KEGG		Reactome
	Cytokine-cytokine receptor interaction JAK-STAT signaling pathway Th17 cell differentiation Inflammatory bowel disease		Interleukin-21 signaling

Show/Hide Unknown Diseases (8)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Asthma	Asthma in any disease, Asthma, Asthma (childhood onset), Atopic asthma	N/A	N/A	GWAS
Biliary Cholangitis	Primary biliary cholangitis	N/A	N/A	GWAS
Cholangitis	cryptosporidiosis-chronic cholangitis-liver disease syndrome	N/A	N/A	GenCC
Hypothyroidism	Hypothyroidism	N/A	N/A	GWAS
Inflammatory Bowel Disease	Inflammatory bowel disease	N/A	N/A	GWAS
Leprosy	Leprosy	N/A	N/A	GWAS
Ulcerative colitis	Ulcerative colitis	N/A	N/A	GWAS
Vitiligo	Vitiligo	N/A	N/A	GWAS

Show/Hide Text Mining Associations (53)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Ablepharon macrostomia syndrome	Associate	39457093
Arthritis Rheumatoid	Stimulate	17032244, 26482544
Arthritis Rheumatoid	Associate	24757284, 37107636
Brain Ischemia	Associate	26705256
Breast Neoplasms	Associate	36189580
Carcinoma Hepatocellular	Associate	30758075
Carcinoma Non Small Cell Lung	Associate	31573051
Chronic Disease	Associate	24757284
Colitis Ulcerative	Associate	37843347
Common Variable Immunodeficiency	Associate	18254984, 35570134
Congenital disorder of glycosylation type 1L	Inhibit	33929673
Coronary Aneurysm	Associate	27095356
COVID 19	Associate	35859327
Cryptosporidiosis	Associate	33929673
Cytomegalovirus Infections	Associate	33710028
Dermatomyositis	Associate	28836555
Diabetes Mellitus Type 2	Inhibit	27095356
Hepatitis B	Associate	30758075
Hereditary leiomyomatosis and renal cell cancer	Associate	18684866
HIV Infections	Associate	21531891, 33710028
HTLV I Infections	Associate	22530560
Immunologic Deficiency Syndromes	Associate	23440042, 24159173
Infections	Associate	33929673
Inflammatory Bowel Diseases	Associate	16682426, 24757284
Leukemia Lymphocytic Chronic B Cell	Associate	20081380, 26158860
Leukemia Lymphoma Adult T Cell	Associate	15638850
Liver Cirrhosis	Associate	30758075
Liver Cirrhosis Biliary	Associate	28425483
Lupus Erythematosus Systemic	Inhibit	19644854
Lupus Erythematosus Systemic	Associate	19644854
Lupus Erythematosus Systemic	Stimulate	36180106
Lymphatic Metastasis	Associate	30082491
Multiple Myeloma	Associate	11986233, 28057743
Multiple Sclerosis	Associate	21281812
Multiple Sclerosis	Stimulate	23469245
Neoplasms	Associate	18829491, 30103640, 33527196
Neoplasms	Inhibit	31573051
Organizing Pneumonia	Associate	33929673
Paroxysmal ventricular fibrillation	Associate	33305818
Peripheral Arterial Disease	Associate	26705256
Peripheral Arterial Disease	Stimulate	26705256
Polymyositis	Associate	28836555
Primary Immunodeficiency Diseases	Associate	23440042, 26162572
Sezary Syndrome	Associate	21938013
Sjogren's Syndrome	Associate	22030011
Sjogren's Syndrome	Stimulate	26884645
Squamous Cell Carcinoma of Head and Neck	Associate	32719094, 37210507, 37988195
Stomach Neoplasms	Associate	30103640
Tendinopathy	Associate	24757284
Triple Negative Breast Neoplasms	Associate	30082491
Virus Diseases	Associate	23830147
Waldenstrom Macroglobulinemia	Associate	22976953, 30402490
X Linked Combined Immunodeficiency Diseases	Associate	33929673

IL21R (interleukin 21 receptor)