Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	5054
Gene name Gene Name - the full gene name approved by the HGNC.	Serpin family E member 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SERPINE1
Synonyms (NCBI Gene) Gene synonyms aliases	PAI, PAI-1, PAI1, PLANH1
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7q22.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as

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SNP ID	Visualize variation	Clinical significance	Consequence
rs1799762	->G	Pathogenic, other	Upstream transcript variant
rs1194865614	->TA	Pathogenic	Coding sequence variant, frameshift variant
rs1554362148	->C	Pathogenic	Coding sequence variant, frameshift variant
rs1584902091	ACATGAGTTCATCTATTTCCTGCCCACATCTGGTATAAAAGGAGGCAGTGGCCCACAGAGGAGCACAGCTGTGTTTGGCTGCAGGGCCAAGAGCGCTGTCAAGAAGACCCACACGCCCCCCTCCAGCAGCTGAATTCCTGCAGCTCAGCAGCCGCCGCCAGAGCAGGACGAACCGCCAATCGCAAGGCACCTCTGAGAACTTCAGGTAGGAGAAAAGCAAACTCCCTCCAACCTCTTACTTCGGGCTTAAGGCAG	Likely-pathogenic	5 prime UTR variant, upstream transcript variant, intron variant, splice donor variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT005844	hsa-miR-204-5p	Microarray	21282569
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay	21175428
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay	21175428
MIRT005972	hsa-miR-301a-3p	Luciferase reporter assay	21175428
MIRT005972	hsa-miR-301a-3p	Luciferase reporter assay	21175428
MIRT005973	hsa-miR-99a-5p	Luciferase reporter assay	21175428
MIRT005973	hsa-miR-99a-5p	Luciferase reporter assay	21175428
MIRT006316	hsa-miR-143-3p	Immunoblot, Luciferase reporter assay, qRT-PCR, Western blot	22108519
MIRT006317	hsa-miR-145-5p	Immunoblot, Luciferase reporter assay, qRT-PCR, Western blot	22108519
MIRT006316	hsa-miR-143-3p	Immunoblot, Luciferase reporter assay, qRT-PCR, Western blot	22108519
MIRT006317	hsa-miR-145-5p	Immunoblot, Luciferase reporter assay, qRT-PCR, Western blot	22108519
MIRT006316	hsa-miR-143-3p	Immunoblot, Luciferase reporter assay, qRT-PCR, Western blot	22108519
MIRT006317	hsa-miR-145-5p	Immunoblot, Luciferase reporter assay, qRT-PCR, Western blot	22108519
MIRT021688	hsa-miR-138-5p	qRT-PCR	21770894
MIRT022189	hsa-miR-124-3p	Microarray	18668037
MIRT053477	hsa-miR-148a-3p	Luciferase reporter assay, Microarray, qRT-PCR	21703006
MIRT054106	hsa-miR-486-5p	qRT-PCR	22995304
MIRT054139	hsa-miR-30b-5p	GFP reporter assay, Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	25170877
MIRT054139	hsa-miR-30b-5p	GFP reporter assay, Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	25170877
MIRT006317	hsa-miR-145-5p	qRT-PCR	23312222
MIRT006317	hsa-miR-145-5p	qRT-PCR	23312222
MIRT244294	hsa-miR-224-5p	PAR-CLIP	22012620
MIRT244292	hsa-miR-30a-5p	PAR-CLIP	22012620
MIRT054139	hsa-miR-30b-5p	PAR-CLIP	22012620
MIRT005971	hsa-miR-30c-5p	PAR-CLIP	22012620
MIRT244293	hsa-miR-30d-5p	PAR-CLIP	22012620
MIRT244295	hsa-miR-30e-5p	PAR-CLIP	22012620
MIRT534387	hsa-miR-1273d	PAR-CLIP	22012620
MIRT244297	hsa-miR-6882-5p	PAR-CLIP	22012620
MIRT534386	hsa-miR-3145-5p	PAR-CLIP	22012620
MIRT534385	hsa-miR-519d-5p	PAR-CLIP	22012620
MIRT534384	hsa-miR-3977	PAR-CLIP	22012620
MIRT731180	hsa-miR-10a-5p	qRT-PCR, ELISA, Luciferase reporter assay, Western blot	25554417
MIRT731180	hsa-miR-10a-5p	qRT-PCR, ELISA, Luciferase reporter assay, Western blot	25554417
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT005971	hsa-miR-30c-5p	Luciferase reporter assay, qRT-PCR, Western blot	27819307
MIRT006316	hsa-miR-143-3p	Luciferase reporter assay, Western blot	26817521
MIRT006316	hsa-miR-143-3p	Luciferase reporter assay, Western blot	26817521
MIRT006317	hsa-miR-145-5p	Luciferase reporter assay, Western blotting, Immunoprecipitaion (IP), Immunohistochemistry (IHC), qRT-PCR, In situ hybridization	33512745
MIRT006317	hsa-miR-145-5p	Luciferase reporter assay, Western blotting, qRT-PCR	34249676
MIRT737068	hsa-miR-181c-5p	Luciferase reporter assay, Western blotting, qRT-PCR	33680908
MIRT244294	hsa-miR-224-5p	PAR-CLIP	22012620
MIRT244292	hsa-miR-30a-5p	PAR-CLIP	22012620
MIRT054139	hsa-miR-30b-5p	PAR-CLIP	22012620
MIRT005971	hsa-miR-30c-5p	PAR-CLIP	22012620
MIRT244293	hsa-miR-30d-5p	PAR-CLIP	22012620
MIRT244295	hsa-miR-30e-5p	PAR-CLIP	22012620
MIRT534387	hsa-miR-1273d	PAR-CLIP	22012620
MIRT244297	hsa-miR-6882-5p	PAR-CLIP	22012620
MIRT534386	hsa-miR-3145-5p	PAR-CLIP	22012620
MIRT534385	hsa-miR-519d-5p	PAR-CLIP	22012620
MIRT534384	hsa-miR-3977	PAR-CLIP	22012620
MIRT005973	hsa-miR-99a-5p	Luciferase reporter assay, Western blotting, qRT-PCR, In situ hybridization, Flow cytometry	37531026
MIRT755774	hsa-miR-30e-3p	Luciferase reporter assay, Western blotting, qRT-PCR, Immunohistochemistry (IHC)	35409173
MIRT244293	hsa-miR-30d-5p	Luciferase reporter assay, Western blotting, qRT-PCR	38393683
MIRT1338847	hsa-miR-2277-5p	CLIP-seq
MIRT1338848	hsa-miR-3178	CLIP-seq
MIRT1338849	hsa-miR-3184	CLIP-seq
MIRT1338850	hsa-miR-423-5p	CLIP-seq
MIRT1338851	hsa-miR-4488	CLIP-seq
MIRT1338852	hsa-miR-4634	CLIP-seq
MIRT1338853	hsa-miR-4697-5p	CLIP-seq
MIRT1338854	hsa-miR-583	CLIP-seq
MIRT1338855	hsa-miR-1244	CLIP-seq
MIRT1338856	hsa-miR-1343	CLIP-seq
MIRT1338857	hsa-miR-181a	CLIP-seq
MIRT1338858	hsa-miR-181b	CLIP-seq
MIRT1338859	hsa-miR-181c	CLIP-seq
MIRT1338860	hsa-miR-181d	CLIP-seq
MIRT1338861	hsa-miR-2117	CLIP-seq
MIRT1338862	hsa-miR-23a	CLIP-seq
MIRT1338863	hsa-miR-23b	CLIP-seq
MIRT1338864	hsa-miR-23c	CLIP-seq
MIRT1338865	hsa-miR-3168	CLIP-seq
MIRT1338866	hsa-miR-34a	CLIP-seq
MIRT1338867	hsa-miR-34c-5p	CLIP-seq
MIRT1338868	hsa-miR-3545-3p	CLIP-seq
MIRT1338869	hsa-miR-3663-5p	CLIP-seq
MIRT1338870	hsa-miR-378g	CLIP-seq
MIRT1338871	hsa-miR-425	CLIP-seq
MIRT1338872	hsa-miR-4258	CLIP-seq
MIRT1338873	hsa-miR-4262	CLIP-seq
MIRT1338874	hsa-miR-4265	CLIP-seq
MIRT1338875	hsa-miR-4296	CLIP-seq
MIRT1338876	hsa-miR-4302	CLIP-seq
MIRT1338877	hsa-miR-4322	CLIP-seq
MIRT1338878	hsa-miR-4417	CLIP-seq
MIRT1338879	hsa-miR-4423-5p	CLIP-seq
MIRT1338880	hsa-miR-4437	CLIP-seq
MIRT1338881	hsa-miR-4457	CLIP-seq
MIRT1338882	hsa-miR-449a	CLIP-seq
MIRT1338883	hsa-miR-449b	CLIP-seq
MIRT1338884	hsa-miR-4635	CLIP-seq
MIRT1338885	hsa-miR-4674	CLIP-seq
MIRT1338886	hsa-miR-4680-5p	CLIP-seq
MIRT1338887	hsa-miR-4753-3p	CLIP-seq
MIRT1338888	hsa-miR-4760-5p	CLIP-seq
MIRT1338889	hsa-miR-4761-5p	CLIP-seq
MIRT1338890	hsa-miR-4768-5p	CLIP-seq
MIRT1338891	hsa-miR-4781-3p	CLIP-seq
MIRT1338892	hsa-miR-579	CLIP-seq
MIRT1338893	hsa-miR-624	CLIP-seq
MIRT1338894	hsa-miR-642b	CLIP-seq
MIRT1338895	hsa-miR-664	CLIP-seq
MIRT1553379	hsa-miR-103a	CLIP-seq
MIRT1553380	hsa-miR-107	CLIP-seq
MIRT1553381	hsa-miR-1179	CLIP-seq
MIRT1553382	hsa-miR-1184	CLIP-seq
MIRT1553383	hsa-miR-1200	CLIP-seq
MIRT1553384	hsa-miR-1208	CLIP-seq
MIRT1553385	hsa-miR-1226	CLIP-seq
MIRT1338855	hsa-miR-1244	CLIP-seq
MIRT1553386	hsa-miR-1245b-3p	CLIP-seq
MIRT1553387	hsa-miR-1252	CLIP-seq
MIRT1553388	hsa-miR-1270	CLIP-seq
MIRT1553389	hsa-miR-1273f	CLIP-seq
MIRT1553390	hsa-miR-1275	CLIP-seq
MIRT1553391	hsa-miR-128	CLIP-seq
MIRT1553392	hsa-miR-1290	CLIP-seq
MIRT1553393	hsa-miR-130a	CLIP-seq
MIRT1553394	hsa-miR-130b	CLIP-seq
MIRT1553395	hsa-miR-143	CLIP-seq
MIRT1553396	hsa-miR-145	CLIP-seq
MIRT1553397	hsa-miR-148a	CLIP-seq
MIRT1553398	hsa-miR-148b	CLIP-seq
MIRT1553399	hsa-miR-150	CLIP-seq
MIRT1553400	hsa-miR-152	CLIP-seq
MIRT1553401	hsa-miR-1587	CLIP-seq
MIRT1338857	hsa-miR-181a	CLIP-seq
MIRT1338858	hsa-miR-181b	CLIP-seq
MIRT1338859	hsa-miR-181c	CLIP-seq
MIRT1338860	hsa-miR-181d	CLIP-seq
MIRT1553402	hsa-miR-1825	CLIP-seq
MIRT1553403	hsa-miR-1915	CLIP-seq
MIRT1553404	hsa-miR-193a-3p	CLIP-seq
MIRT1553405	hsa-miR-193b	CLIP-seq
MIRT1553406	hsa-miR-1972	CLIP-seq
MIRT1553407	hsa-miR-199a-5p	CLIP-seq
MIRT1553408	hsa-miR-199b-5p	CLIP-seq
MIRT1553409	hsa-miR-19a	CLIP-seq
MIRT1553410	hsa-miR-19b	CLIP-seq
MIRT1338861	hsa-miR-2117	CLIP-seq
MIRT1553411	hsa-miR-218	CLIP-seq
MIRT1553412	hsa-miR-2355-3p	CLIP-seq
MIRT1553413	hsa-miR-2355-5p	CLIP-seq
MIRT1338862	hsa-miR-23a	CLIP-seq
MIRT1338863	hsa-miR-23b	CLIP-seq
MIRT1338864	hsa-miR-23c	CLIP-seq
MIRT1553414	hsa-miR-28-5p	CLIP-seq
MIRT1553415	hsa-miR-297	CLIP-seq
MIRT1553416	hsa-miR-299-5p	CLIP-seq
MIRT1553417	hsa-miR-301a	CLIP-seq
MIRT1553418	hsa-miR-301b	CLIP-seq
MIRT1553419	hsa-miR-3064-3p	CLIP-seq
MIRT1553420	hsa-miR-3065-3p	CLIP-seq
MIRT1553421	hsa-miR-3124-3p	CLIP-seq
MIRT1553422	hsa-miR-3139	CLIP-seq
MIRT1553423	hsa-miR-3147	CLIP-seq
MIRT1553424	hsa-miR-3149	CLIP-seq
MIRT1553425	hsa-miR-3150a-3p	CLIP-seq
MIRT1553426	hsa-miR-3163	CLIP-seq
MIRT1338865	hsa-miR-3168	CLIP-seq
MIRT1553427	hsa-miR-3173-3p	CLIP-seq
MIRT1553428	hsa-miR-3175	CLIP-seq
MIRT1553429	hsa-miR-3176	CLIP-seq
MIRT1553430	hsa-miR-3186-5p	CLIP-seq
MIRT1553431	hsa-miR-3201	CLIP-seq
MIRT1553432	hsa-miR-331-3p	CLIP-seq
MIRT1553433	hsa-miR-331-5p	CLIP-seq
MIRT1553434	hsa-miR-337-3p	CLIP-seq
MIRT1553435	hsa-miR-3605-5p	CLIP-seq
MIRT1553436	hsa-miR-3613-3p	CLIP-seq
MIRT1553437	hsa-miR-3652	CLIP-seq
MIRT1553438	hsa-miR-3666	CLIP-seq
MIRT1553439	hsa-miR-3679-3p	CLIP-seq
MIRT1553440	hsa-miR-3691-5p	CLIP-seq
MIRT1553441	hsa-miR-378	CLIP-seq
MIRT1553442	hsa-miR-378b	CLIP-seq
MIRT1553443	hsa-miR-378c	CLIP-seq
MIRT1553444	hsa-miR-378d	CLIP-seq
MIRT1553445	hsa-miR-378e	CLIP-seq
MIRT1553446	hsa-miR-378f	CLIP-seq
MIRT1553447	hsa-miR-378h	CLIP-seq
MIRT1553448	hsa-miR-378i	CLIP-seq
MIRT1553449	hsa-miR-3920	CLIP-seq
MIRT1553450	hsa-miR-3921	CLIP-seq
MIRT1553451	hsa-miR-3922-3p	CLIP-seq
MIRT1553452	hsa-miR-3925-3p	CLIP-seq
MIRT1553453	hsa-miR-421	CLIP-seq
MIRT1553454	hsa-miR-422a	CLIP-seq
MIRT1553455	hsa-miR-4251	CLIP-seq
MIRT1553456	hsa-miR-4259	CLIP-seq
MIRT1338873	hsa-miR-4262	CLIP-seq
MIRT1553457	hsa-miR-4272	CLIP-seq
MIRT1553458	hsa-miR-4276	CLIP-seq
MIRT1553459	hsa-miR-4286	CLIP-seq
MIRT1553460	hsa-miR-4295	CLIP-seq
MIRT1553461	hsa-miR-4314	CLIP-seq
MIRT1553462	hsa-miR-432	CLIP-seq
MIRT1553463	hsa-miR-4324	CLIP-seq
MIRT1553464	hsa-miR-4328	CLIP-seq
MIRT1553465	hsa-miR-4329	CLIP-seq
MIRT1338878	hsa-miR-4417	CLIP-seq
MIRT1553466	hsa-miR-4419a	CLIP-seq
MIRT1553467	hsa-miR-4422	CLIP-seq
MIRT1553468	hsa-miR-4428	CLIP-seq
MIRT1553469	hsa-miR-4430	CLIP-seq
MIRT1553470	hsa-miR-4434	CLIP-seq
MIRT1553471	hsa-miR-4435	CLIP-seq
MIRT1553472	hsa-miR-4436b-5p	CLIP-seq
MIRT1553473	hsa-miR-4475	CLIP-seq
MIRT1553474	hsa-miR-4492	CLIP-seq
MIRT1553475	hsa-miR-4493	CLIP-seq
MIRT1553476	hsa-miR-4498	CLIP-seq
MIRT1553477	hsa-miR-4505	CLIP-seq
MIRT1553478	hsa-miR-4510	CLIP-seq
MIRT1553479	hsa-miR-4516	CLIP-seq
MIRT1553480	hsa-miR-452	CLIP-seq
MIRT1553481	hsa-miR-4522	CLIP-seq
MIRT1553482	hsa-miR-4525	CLIP-seq
MIRT1553483	hsa-miR-4531	CLIP-seq
MIRT1553484	hsa-miR-454	CLIP-seq
MIRT1553485	hsa-miR-4639-3p	CLIP-seq
MIRT1553486	hsa-miR-4640-5p	CLIP-seq
MIRT1553487	hsa-miR-4646-3p	CLIP-seq
MIRT1553488	hsa-miR-4653-5p	CLIP-seq
MIRT1553489	hsa-miR-4656	CLIP-seq
MIRT1553490	hsa-miR-4659a-3p	CLIP-seq
MIRT1553491	hsa-miR-4659b-3p	CLIP-seq
MIRT1553492	hsa-miR-4665-5p	CLIP-seq
MIRT1553493	hsa-miR-4666-3p	CLIP-seq
MIRT1553494	hsa-miR-4667-5p	CLIP-seq
MIRT1553495	hsa-miR-4675	CLIP-seq
MIRT1553496	hsa-miR-4676-3p	CLIP-seq
MIRT1553497	hsa-miR-4700-5p	CLIP-seq
MIRT1553498	hsa-miR-4704-5p	CLIP-seq
MIRT1553499	hsa-miR-4708-5p	CLIP-seq
MIRT1553500	hsa-miR-4713-5p	CLIP-seq
MIRT1553501	hsa-miR-4714-5p	CLIP-seq
MIRT1553502	hsa-miR-4715-3p	CLIP-seq
MIRT1553503	hsa-miR-4723-5p	CLIP-seq
MIRT1553504	hsa-miR-4726-5p	CLIP-seq
MIRT1553505	hsa-miR-4727-5p	CLIP-seq
MIRT1553506	hsa-miR-4728-5p	CLIP-seq
MIRT1553507	hsa-miR-4741	CLIP-seq
MIRT1553508	hsa-miR-4752	CLIP-seq
MIRT1338887	hsa-miR-4753-3p	CLIP-seq
MIRT1553509	hsa-miR-4755-3p	CLIP-seq
MIRT1338888	hsa-miR-4760-5p	CLIP-seq
MIRT1553510	hsa-miR-4768-3p	CLIP-seq
MIRT1338890	hsa-miR-4768-5p	CLIP-seq
MIRT1553511	hsa-miR-4769-3p	CLIP-seq
MIRT1553512	hsa-miR-4770	CLIP-seq
MIRT1553513	hsa-miR-4778-3p	CLIP-seq
MIRT1553514	hsa-miR-4791	CLIP-seq
MIRT1553515	hsa-miR-4795-3p	CLIP-seq
MIRT1553516	hsa-miR-4802-3p	CLIP-seq
MIRT1553517	hsa-miR-483-5p	CLIP-seq
MIRT1553518	hsa-miR-488	CLIP-seq
MIRT1553519	hsa-miR-514	CLIP-seq
MIRT1553520	hsa-miR-514b-3p	CLIP-seq
MIRT1553521	hsa-miR-532-3p	CLIP-seq
MIRT1553522	hsa-miR-541	CLIP-seq
MIRT1553523	hsa-miR-544b	CLIP-seq
MIRT1553524	hsa-miR-548ac	CLIP-seq
MIRT1553525	hsa-miR-548c-3p	CLIP-seq
MIRT1553526	hsa-miR-548d-3p	CLIP-seq
MIRT1553527	hsa-miR-548z	CLIP-seq
MIRT1553528	hsa-miR-571	CLIP-seq
MIRT1338892	hsa-miR-579	CLIP-seq
MIRT1338854	hsa-miR-583	CLIP-seq
MIRT1553529	hsa-miR-593	CLIP-seq
MIRT1553530	hsa-miR-609	CLIP-seq
MIRT1553531	hsa-miR-617	CLIP-seq
MIRT1553532	hsa-miR-620	CLIP-seq
MIRT1553533	hsa-miR-625	CLIP-seq
MIRT1553534	hsa-miR-636	CLIP-seq
MIRT1553535	hsa-miR-637	CLIP-seq
MIRT1553536	hsa-miR-640	CLIP-seq
MIRT1338894	hsa-miR-642b	CLIP-seq
MIRT1553537	hsa-miR-654-5p	CLIP-seq
MIRT1553538	hsa-miR-656	CLIP-seq
MIRT1338895	hsa-miR-664	CLIP-seq
MIRT1553539	hsa-miR-665	CLIP-seq
MIRT1553540	hsa-miR-708	CLIP-seq
MIRT1553541	hsa-miR-762	CLIP-seq
MIRT1553542	hsa-miR-766	CLIP-seq
MIRT1553543	hsa-miR-939	CLIP-seq
MIRT1553384	hsa-miR-1208	CLIP-seq
MIRT1553390	hsa-miR-1275	CLIP-seq
MIRT1553406	hsa-miR-1972	CLIP-seq
MIRT1557015	hsa-miR-224	CLIP-seq
MIRT1553423	hsa-miR-3147	CLIP-seq
MIRT1553425	hsa-miR-3150a-3p	CLIP-seq
MIRT1557016	hsa-miR-33a	CLIP-seq
MIRT1557017	hsa-miR-33b	CLIP-seq
MIRT1553456	hsa-miR-4259	CLIP-seq
MIRT1553461	hsa-miR-4314	CLIP-seq
MIRT1553471	hsa-miR-4435	CLIP-seq
MIRT1553480	hsa-miR-452	CLIP-seq
MIRT1553483	hsa-miR-4531	CLIP-seq
MIRT1553486	hsa-miR-4640-5p	CLIP-seq
MIRT1553492	hsa-miR-4665-5p	CLIP-seq
MIRT1553494	hsa-miR-4667-5p	CLIP-seq
MIRT1553496	hsa-miR-4676-3p	CLIP-seq
MIRT1553497	hsa-miR-4700-5p	CLIP-seq
MIRT1553504	hsa-miR-4726-5p	CLIP-seq
MIRT1553509	hsa-miR-4755-3p	CLIP-seq
MIRT1553510	hsa-miR-4768-3p	CLIP-seq
MIRT1557018	hsa-miR-544	CLIP-seq
MIRT1553528	hsa-miR-571	CLIP-seq
MIRT1553535	hsa-miR-637	CLIP-seq
MIRT1553539	hsa-miR-665	CLIP-seq
MIRT1553379	hsa-miR-103a	CLIP-seq
MIRT1553380	hsa-miR-107	CLIP-seq
MIRT1553382	hsa-miR-1184	CLIP-seq
MIRT2100176	hsa-miR-2682	CLIP-seq
MIRT1553420	hsa-miR-3065-3p	CLIP-seq
MIRT1553426	hsa-miR-3163	CLIP-seq
MIRT2100177	hsa-miR-449c	CLIP-seq
MIRT2100178	hsa-miR-4692	CLIP-seq
MIRT1553502	hsa-miR-4715-3p	CLIP-seq
MIRT1553525	hsa-miR-548c-3p	CLIP-seq
MIRT1338857	hsa-miR-181a	CLIP-seq
MIRT1338858	hsa-miR-181b	CLIP-seq
MIRT1338859	hsa-miR-181c	CLIP-seq
MIRT1338860	hsa-miR-181d	CLIP-seq
MIRT1553402	hsa-miR-1825	CLIP-seq
MIRT1338873	hsa-miR-4262	CLIP-seq
MIRT2432997	hsa-miR-106a	CLIP-seq
MIRT2432998	hsa-miR-106b	CLIP-seq
MIRT1553381	hsa-miR-1179	CLIP-seq
MIRT1553384	hsa-miR-1208	CLIP-seq
MIRT1338855	hsa-miR-1244	CLIP-seq
MIRT1553386	hsa-miR-1245b-3p	CLIP-seq
MIRT1553389	hsa-miR-1273f	CLIP-seq
MIRT1553391	hsa-miR-128	CLIP-seq
MIRT1553393	hsa-miR-130a	CLIP-seq
MIRT1553394	hsa-miR-130b	CLIP-seq
MIRT1338856	hsa-miR-1343	CLIP-seq
MIRT1553395	hsa-miR-143	CLIP-seq
MIRT1553396	hsa-miR-145	CLIP-seq
MIRT1553397	hsa-miR-148a	CLIP-seq
MIRT1553398	hsa-miR-148b	CLIP-seq
MIRT1553399	hsa-miR-150	CLIP-seq
MIRT1553400	hsa-miR-152	CLIP-seq
MIRT2432999	hsa-miR-17	CLIP-seq
MIRT1338857	hsa-miR-181a	CLIP-seq
MIRT1338858	hsa-miR-181b	CLIP-seq
MIRT1338859	hsa-miR-181c	CLIP-seq
MIRT1338860	hsa-miR-181d	CLIP-seq
MIRT1553402	hsa-miR-1825	CLIP-seq
MIRT1553407	hsa-miR-199a-5p	CLIP-seq
MIRT1553408	hsa-miR-199b-5p	CLIP-seq
MIRT1553409	hsa-miR-19a	CLIP-seq
MIRT1553410	hsa-miR-19b	CLIP-seq
MIRT2433000	hsa-miR-20a	CLIP-seq
MIRT2433001	hsa-miR-20b	CLIP-seq
MIRT2433002	hsa-miR-2110	CLIP-seq
MIRT1338861	hsa-miR-2117	CLIP-seq
MIRT1553412	hsa-miR-2355-3p	CLIP-seq
MIRT1338862	hsa-miR-23a	CLIP-seq
MIRT1338863	hsa-miR-23b	CLIP-seq
MIRT1338864	hsa-miR-23c	CLIP-seq
MIRT1553414	hsa-miR-28-5p	CLIP-seq
MIRT1553417	hsa-miR-301a	CLIP-seq
MIRT1553418	hsa-miR-301b	CLIP-seq
MIRT1553419	hsa-miR-3064-3p	CLIP-seq
MIRT1553421	hsa-miR-3124-3p	CLIP-seq
MIRT1553422	hsa-miR-3139	CLIP-seq
MIRT1553425	hsa-miR-3150a-3p	CLIP-seq
MIRT2433003	hsa-miR-3153	CLIP-seq
MIRT1553426	hsa-miR-3163	CLIP-seq
MIRT1338865	hsa-miR-3168	CLIP-seq
MIRT1553428	hsa-miR-3175	CLIP-seq
MIRT1553431	hsa-miR-3201	CLIP-seq
MIRT1553433	hsa-miR-331-5p	CLIP-seq
MIRT1553434	hsa-miR-337-3p	CLIP-seq
MIRT1557016	hsa-miR-33a	CLIP-seq
MIRT1557017	hsa-miR-33b	CLIP-seq
MIRT1338868	hsa-miR-3545-3p	CLIP-seq
MIRT2433004	hsa-miR-3609	CLIP-seq
MIRT1553436	hsa-miR-3613-3p	CLIP-seq
MIRT1553438	hsa-miR-3666	CLIP-seq
MIRT1553440	hsa-miR-3691-5p	CLIP-seq
MIRT1338870	hsa-miR-378g	CLIP-seq
MIRT1553449	hsa-miR-3920	CLIP-seq
MIRT1553450	hsa-miR-3921	CLIP-seq
MIRT1553452	hsa-miR-3925-3p	CLIP-seq
MIRT1553453	hsa-miR-421	CLIP-seq
MIRT1553455	hsa-miR-4251	CLIP-seq
MIRT1338872	hsa-miR-4258	CLIP-seq
MIRT1338873	hsa-miR-4262	CLIP-seq
MIRT2433005	hsa-miR-4268	CLIP-seq
MIRT2433006	hsa-miR-4269	CLIP-seq
MIRT2433007	hsa-miR-4271	CLIP-seq
MIRT1553457	hsa-miR-4272	CLIP-seq
MIRT2433008	hsa-miR-4282	CLIP-seq
MIRT1553460	hsa-miR-4295	CLIP-seq
MIRT1553461	hsa-miR-4314	CLIP-seq
MIRT1553464	hsa-miR-4328	CLIP-seq
MIRT1553465	hsa-miR-4329	CLIP-seq
MIRT1553466	hsa-miR-4419a	CLIP-seq
MIRT1553467	hsa-miR-4422	CLIP-seq
MIRT1338880	hsa-miR-4437	CLIP-seq
MIRT2433009	hsa-miR-4448	CLIP-seq
MIRT1553475	hsa-miR-4493	CLIP-seq
MIRT1553478	hsa-miR-4510	CLIP-seq
MIRT2433010	hsa-miR-4512	CLIP-seq
MIRT1553480	hsa-miR-452	CLIP-seq
MIRT1553481	hsa-miR-4522	CLIP-seq
MIRT1553484	hsa-miR-454	CLIP-seq
MIRT2433011	hsa-miR-4645-5p	CLIP-seq
MIRT1553487	hsa-miR-4646-3p	CLIP-seq
MIRT1553488	hsa-miR-4653-5p	CLIP-seq
MIRT1553490	hsa-miR-4659a-3p	CLIP-seq
MIRT1553491	hsa-miR-4659b-3p	CLIP-seq
MIRT1553493	hsa-miR-4666-3p	CLIP-seq
MIRT2433012	hsa-miR-4666-5p	CLIP-seq
MIRT1553494	hsa-miR-4667-5p	CLIP-seq
MIRT2433013	hsa-miR-4673	CLIP-seq
MIRT1338885	hsa-miR-4674	CLIP-seq
MIRT1553496	hsa-miR-4676-3p	CLIP-seq
MIRT1338886	hsa-miR-4680-5p	CLIP-seq
MIRT1553497	hsa-miR-4700-5p	CLIP-seq
MIRT1553498	hsa-miR-4704-5p	CLIP-seq
MIRT1553499	hsa-miR-4708-5p	CLIP-seq
MIRT1553500	hsa-miR-4713-5p	CLIP-seq
MIRT1553501	hsa-miR-4714-5p	CLIP-seq
MIRT2433014	hsa-miR-4725-3p	CLIP-seq
MIRT1553506	hsa-miR-4728-5p	CLIP-seq
MIRT1553508	hsa-miR-4752	CLIP-seq
MIRT1338887	hsa-miR-4753-3p	CLIP-seq
MIRT2433015	hsa-miR-4757-5p	CLIP-seq
MIRT1338888	hsa-miR-4760-5p	CLIP-seq
MIRT1338890	hsa-miR-4768-5p	CLIP-seq
MIRT1553512	hsa-miR-4770	CLIP-seq
MIRT1553513	hsa-miR-4778-3p	CLIP-seq
MIRT1553514	hsa-miR-4791	CLIP-seq
MIRT2433016	hsa-miR-4793-5p	CLIP-seq
MIRT1553515	hsa-miR-4795-3p	CLIP-seq
MIRT1553516	hsa-miR-4802-3p	CLIP-seq
MIRT1553517	hsa-miR-483-5p	CLIP-seq
MIRT1553518	hsa-miR-488	CLIP-seq
MIRT2433017	hsa-miR-494	CLIP-seq
MIRT1553519	hsa-miR-514	CLIP-seq
MIRT1553520	hsa-miR-514b-3p	CLIP-seq
MIRT2433018	hsa-miR-518a-5p	CLIP-seq
MIRT2433019	hsa-miR-519a	CLIP-seq
MIRT2433020	hsa-miR-519b-3p	CLIP-seq
MIRT2433021	hsa-miR-519c-3p	CLIP-seq
MIRT2433022	hsa-miR-519d	CLIP-seq
MIRT2433023	hsa-miR-520g	CLIP-seq
MIRT2433024	hsa-miR-520h	CLIP-seq
MIRT2433025	hsa-miR-527	CLIP-seq
MIRT1553521	hsa-miR-532-3p	CLIP-seq
MIRT1557018	hsa-miR-544	CLIP-seq
MIRT2433026	hsa-miR-548ah	CLIP-seq
MIRT1553525	hsa-miR-548c-3p	CLIP-seq
MIRT2433027	hsa-miR-548t	CLIP-seq
MIRT1338892	hsa-miR-579	CLIP-seq
MIRT1553530	hsa-miR-609	CLIP-seq
MIRT1553535	hsa-miR-637	CLIP-seq
MIRT1338894	hsa-miR-642b	CLIP-seq
MIRT1553538	hsa-miR-656	CLIP-seq
MIRT1338895	hsa-miR-664	CLIP-seq
MIRT1553540	hsa-miR-708	CLIP-seq
MIRT2433028	hsa-miR-764	CLIP-seq
MIRT1553542	hsa-miR-766	CLIP-seq
MIRT2433029	hsa-miR-767-3p	CLIP-seq
MIRT2433030	hsa-miR-93	CLIP-seq
MIRT1553543	hsa-miR-939	CLIP-seq
MIRT2433031	hsa-miR-942	CLIP-seq
MIRT1338856	hsa-miR-1343	CLIP-seq
MIRT1338868	hsa-miR-3545-3p	CLIP-seq
MIRT1338869	hsa-miR-3663-5p	CLIP-seq
MIRT1338870	hsa-miR-378g	CLIP-seq
MIRT1338872	hsa-miR-4258	CLIP-seq
MIRT1553459	hsa-miR-4286	CLIP-seq
MIRT1338880	hsa-miR-4437	CLIP-seq
MIRT1338884	hsa-miR-4635	CLIP-seq
MIRT1338885	hsa-miR-4674	CLIP-seq
MIRT1338886	hsa-miR-4680-5p	CLIP-seq
MIRT1553459	hsa-miR-4286	CLIP-seq
MIRT1553379	hsa-miR-103a	CLIP-seq
MIRT1553380	hsa-miR-107	CLIP-seq
MIRT1553382	hsa-miR-1184	CLIP-seq
MIRT1553384	hsa-miR-1208	CLIP-seq
MIRT1553385	hsa-miR-1226	CLIP-seq
MIRT2620656	hsa-miR-1227	CLIP-seq
MIRT1338855	hsa-miR-1244	CLIP-seq
MIRT1553386	hsa-miR-1245b-3p	CLIP-seq
MIRT1553389	hsa-miR-1273f	CLIP-seq
MIRT1553390	hsa-miR-1275	CLIP-seq
MIRT1553391	hsa-miR-128	CLIP-seq
MIRT1553392	hsa-miR-1290	CLIP-seq
MIRT1553393	hsa-miR-130a	CLIP-seq
MIRT1553394	hsa-miR-130b	CLIP-seq
MIRT2620657	hsa-miR-141	CLIP-seq
MIRT1553395	hsa-miR-143	CLIP-seq
MIRT1553396	hsa-miR-145	CLIP-seq
MIRT1553397	hsa-miR-148a	CLIP-seq
MIRT1553398	hsa-miR-148b	CLIP-seq
MIRT1553400	hsa-miR-152	CLIP-seq
MIRT1553401	hsa-miR-1587	CLIP-seq
MIRT1338857	hsa-miR-181a	CLIP-seq
MIRT1338858	hsa-miR-181b	CLIP-seq
MIRT1338859	hsa-miR-181c	CLIP-seq
MIRT1338860	hsa-miR-181d	CLIP-seq
MIRT1553402	hsa-miR-1825	CLIP-seq
MIRT1553403	hsa-miR-1915	CLIP-seq
MIRT1553406	hsa-miR-1972	CLIP-seq
MIRT1553407	hsa-miR-199a-5p	CLIP-seq
MIRT1553408	hsa-miR-199b-5p	CLIP-seq
MIRT1553409	hsa-miR-19a	CLIP-seq
MIRT1553410	hsa-miR-19b	CLIP-seq
MIRT2620658	hsa-miR-200a	CLIP-seq
MIRT1338861	hsa-miR-2117	CLIP-seq
MIRT1553412	hsa-miR-2355-3p	CLIP-seq
MIRT1553414	hsa-miR-28-5p	CLIP-seq
MIRT1553417	hsa-miR-301a	CLIP-seq
MIRT1553418	hsa-miR-301b	CLIP-seq
MIRT1553419	hsa-miR-3064-3p	CLIP-seq
MIRT1553420	hsa-miR-3065-3p	CLIP-seq
MIRT1553421	hsa-miR-3124-3p	CLIP-seq
MIRT1553422	hsa-miR-3139	CLIP-seq
MIRT1553423	hsa-miR-3147	CLIP-seq
MIRT1553425	hsa-miR-3150a-3p	CLIP-seq
MIRT1338865	hsa-miR-3168	CLIP-seq
MIRT1553428	hsa-miR-3175	CLIP-seq
MIRT1553430	hsa-miR-3186-5p	CLIP-seq
MIRT1553431	hsa-miR-3201	CLIP-seq
MIRT1553436	hsa-miR-3613-3p	CLIP-seq
MIRT1553438	hsa-miR-3666	CLIP-seq
MIRT1553440	hsa-miR-3691-5p	CLIP-seq
MIRT1553449	hsa-miR-3920	CLIP-seq
MIRT1553450	hsa-miR-3921	CLIP-seq
MIRT1553452	hsa-miR-3925-3p	CLIP-seq
MIRT1553455	hsa-miR-4251	CLIP-seq
MIRT1553456	hsa-miR-4259	CLIP-seq
MIRT1338873	hsa-miR-4262	CLIP-seq
MIRT2433006	hsa-miR-4269	CLIP-seq
MIRT1553458	hsa-miR-4276	CLIP-seq
MIRT2433008	hsa-miR-4282	CLIP-seq
MIRT1553459	hsa-miR-4286	CLIP-seq
MIRT1553460	hsa-miR-4295	CLIP-seq
MIRT1553461	hsa-miR-4314	CLIP-seq
MIRT1553464	hsa-miR-4328	CLIP-seq
MIRT1553465	hsa-miR-4329	CLIP-seq
MIRT1338878	hsa-miR-4417	CLIP-seq
MIRT1553466	hsa-miR-4419a	CLIP-seq
MIRT1553470	hsa-miR-4434	CLIP-seq
MIRT1553471	hsa-miR-4435	CLIP-seq
MIRT1553474	hsa-miR-4492	CLIP-seq
MIRT1553475	hsa-miR-4493	CLIP-seq
MIRT1553476	hsa-miR-4498	CLIP-seq
MIRT1553478	hsa-miR-4510	CLIP-seq
MIRT1553479	hsa-miR-4516	CLIP-seq
MIRT1553480	hsa-miR-452	CLIP-seq
MIRT1553481	hsa-miR-4522	CLIP-seq
MIRT1553482	hsa-miR-4525	CLIP-seq
MIRT1553483	hsa-miR-4531	CLIP-seq
MIRT1553484	hsa-miR-454	CLIP-seq
MIRT1553485	hsa-miR-4639-3p	CLIP-seq
MIRT1553486	hsa-miR-4640-5p	CLIP-seq
MIRT2433011	hsa-miR-4645-5p	CLIP-seq
MIRT1553487	hsa-miR-4646-3p	CLIP-seq
MIRT2620659	hsa-miR-4651	CLIP-seq
MIRT1553488	hsa-miR-4653-5p	CLIP-seq
MIRT1553489	hsa-miR-4656	CLIP-seq
MIRT1553490	hsa-miR-4659a-3p	CLIP-seq
MIRT1553491	hsa-miR-4659b-3p	CLIP-seq
MIRT1553492	hsa-miR-4665-5p	CLIP-seq
MIRT1553494	hsa-miR-4667-5p	CLIP-seq
MIRT2433013	hsa-miR-4673	CLIP-seq
MIRT1553495	hsa-miR-4675	CLIP-seq
MIRT1553496	hsa-miR-4676-3p	CLIP-seq
MIRT1553497	hsa-miR-4700-5p	CLIP-seq
MIRT1553498	hsa-miR-4704-5p	CLIP-seq
MIRT1553499	hsa-miR-4708-5p	CLIP-seq
MIRT1553501	hsa-miR-4714-5p	CLIP-seq
MIRT1553502	hsa-miR-4715-3p	CLIP-seq
MIRT1553503	hsa-miR-4723-5p	CLIP-seq
MIRT1553504	hsa-miR-4726-5p	CLIP-seq
MIRT1553505	hsa-miR-4727-5p	CLIP-seq
MIRT1553506	hsa-miR-4728-5p	CLIP-seq
MIRT1553507	hsa-miR-4741	CLIP-seq
MIRT1553508	hsa-miR-4752	CLIP-seq
MIRT1338887	hsa-miR-4753-3p	CLIP-seq
MIRT1553509	hsa-miR-4755-3p	CLIP-seq
MIRT1338888	hsa-miR-4760-5p	CLIP-seq
MIRT1553510	hsa-miR-4768-3p	CLIP-seq
MIRT1338890	hsa-miR-4768-5p	CLIP-seq
MIRT1553511	hsa-miR-4769-3p	CLIP-seq
MIRT1553512	hsa-miR-4770	CLIP-seq
MIRT1553513	hsa-miR-4778-3p	CLIP-seq
MIRT1553514	hsa-miR-4791	CLIP-seq
MIRT1553515	hsa-miR-4795-3p	CLIP-seq
MIRT1553516	hsa-miR-4802-3p	CLIP-seq
MIRT1553518	hsa-miR-488	CLIP-seq
MIRT1553522	hsa-miR-541	CLIP-seq
MIRT1553524	hsa-miR-548ac	CLIP-seq
MIRT1553526	hsa-miR-548d-3p	CLIP-seq
MIRT1553527	hsa-miR-548z	CLIP-seq
MIRT1553528	hsa-miR-571	CLIP-seq
MIRT1338854	hsa-miR-583	CLIP-seq
MIRT2620660	hsa-miR-608	CLIP-seq
MIRT1553530	hsa-miR-609	CLIP-seq
MIRT1553533	hsa-miR-625	CLIP-seq
MIRT1553535	hsa-miR-637	CLIP-seq
MIRT1338894	hsa-miR-642b	CLIP-seq
MIRT1553537	hsa-miR-654-5p	CLIP-seq
MIRT1553538	hsa-miR-656	CLIP-seq
MIRT1553539	hsa-miR-665	CLIP-seq
MIRT1553540	hsa-miR-708	CLIP-seq
MIRT1553541	hsa-miR-762	CLIP-seq
MIRT1553542	hsa-miR-766	CLIP-seq
MIRT1553543	hsa-miR-939	CLIP-seq
MIRT1553379	hsa-miR-103a	CLIP-seq
MIRT1553380	hsa-miR-107	CLIP-seq
MIRT1553382	hsa-miR-1184	CLIP-seq
MIRT1553384	hsa-miR-1208	CLIP-seq
MIRT1553385	hsa-miR-1226	CLIP-seq
MIRT2620656	hsa-miR-1227	CLIP-seq
MIRT1553386	hsa-miR-1245b-3p	CLIP-seq
MIRT1553389	hsa-miR-1273f	CLIP-seq
MIRT1553390	hsa-miR-1275	CLIP-seq
MIRT1553391	hsa-miR-128	CLIP-seq
MIRT1553392	hsa-miR-1290	CLIP-seq
MIRT1553393	hsa-miR-130a	CLIP-seq
MIRT1553394	hsa-miR-130b	CLIP-seq
MIRT2620657	hsa-miR-141	CLIP-seq
MIRT1553396	hsa-miR-145	CLIP-seq
MIRT1553397	hsa-miR-148a	CLIP-seq
MIRT1553398	hsa-miR-148b	CLIP-seq
MIRT1553400	hsa-miR-152	CLIP-seq
MIRT1338857	hsa-miR-181a	CLIP-seq
MIRT1338858	hsa-miR-181b	CLIP-seq
MIRT1338859	hsa-miR-181c	CLIP-seq
MIRT1338860	hsa-miR-181d	CLIP-seq
MIRT1553402	hsa-miR-1825	CLIP-seq
MIRT1553406	hsa-miR-1972	CLIP-seq
MIRT1553407	hsa-miR-199a-5p	CLIP-seq
MIRT1553408	hsa-miR-199b-5p	CLIP-seq
MIRT1553409	hsa-miR-19a	CLIP-seq
MIRT1553410	hsa-miR-19b	CLIP-seq
MIRT2620658	hsa-miR-200a	CLIP-seq
MIRT1553412	hsa-miR-2355-3p	CLIP-seq
MIRT1553417	hsa-miR-301a	CLIP-seq
MIRT1553418	hsa-miR-301b	CLIP-seq
MIRT1553419	hsa-miR-3064-3p	CLIP-seq
MIRT1553420	hsa-miR-3065-3p	CLIP-seq
MIRT1553421	hsa-miR-3124-3p	CLIP-seq
MIRT1553423	hsa-miR-3147	CLIP-seq
MIRT1553425	hsa-miR-3150a-3p	CLIP-seq
MIRT1553428	hsa-miR-3175	CLIP-seq
MIRT1553430	hsa-miR-3186-5p	CLIP-seq
MIRT1553436	hsa-miR-3613-3p	CLIP-seq
MIRT1553438	hsa-miR-3666	CLIP-seq
MIRT1553440	hsa-miR-3691-5p	CLIP-seq
MIRT1553450	hsa-miR-3921	CLIP-seq
MIRT1553452	hsa-miR-3925-3p	CLIP-seq
MIRT1553455	hsa-miR-4251	CLIP-seq
MIRT1553456	hsa-miR-4259	CLIP-seq
MIRT1338873	hsa-miR-4262	CLIP-seq
MIRT2433006	hsa-miR-4269	CLIP-seq
MIRT2433008	hsa-miR-4282	CLIP-seq
MIRT1553460	hsa-miR-4295	CLIP-seq
MIRT1553461	hsa-miR-4314	CLIP-seq
MIRT1553464	hsa-miR-4328	CLIP-seq
MIRT1553465	hsa-miR-4329	CLIP-seq
MIRT1553466	hsa-miR-4419a	CLIP-seq
MIRT1553471	hsa-miR-4435	CLIP-seq
MIRT1553475	hsa-miR-4493	CLIP-seq
MIRT1553478	hsa-miR-4510	CLIP-seq
MIRT1553480	hsa-miR-452	CLIP-seq
MIRT1553481	hsa-miR-4522	CLIP-seq
MIRT1553482	hsa-miR-4525	CLIP-seq
MIRT1553484	hsa-miR-454	CLIP-seq
MIRT1553485	hsa-miR-4639-3p	CLIP-seq
MIRT1553486	hsa-miR-4640-5p	CLIP-seq
MIRT2433011	hsa-miR-4645-5p	CLIP-seq
MIRT1553487	hsa-miR-4646-3p	CLIP-seq
MIRT2620659	hsa-miR-4651	CLIP-seq
MIRT1553488	hsa-miR-4653-5p	CLIP-seq
MIRT1553490	hsa-miR-4659a-3p	CLIP-seq
MIRT1553491	hsa-miR-4659b-3p	CLIP-seq
MIRT1553492	hsa-miR-4665-5p	CLIP-seq
MIRT1553494	hsa-miR-4667-5p	CLIP-seq
MIRT2433013	hsa-miR-4673	CLIP-seq
MIRT1553496	hsa-miR-4676-3p	CLIP-seq
MIRT1553497	hsa-miR-4700-5p	CLIP-seq
MIRT1553498	hsa-miR-4704-5p	CLIP-seq
MIRT1553501	hsa-miR-4714-5p	CLIP-seq
MIRT1553502	hsa-miR-4715-3p	CLIP-seq
MIRT1553503	hsa-miR-4723-5p	CLIP-seq
MIRT1553504	hsa-miR-4726-5p	CLIP-seq
MIRT1553505	hsa-miR-4727-5p	CLIP-seq
MIRT1553506	hsa-miR-4728-5p	CLIP-seq
MIRT1553508	hsa-miR-4752	CLIP-seq
MIRT1553509	hsa-miR-4755-3p	CLIP-seq
MIRT1553510	hsa-miR-4768-3p	CLIP-seq
MIRT1553511	hsa-miR-4769-3p	CLIP-seq
MIRT1553513	hsa-miR-4778-3p	CLIP-seq
MIRT1553516	hsa-miR-4802-3p	CLIP-seq
MIRT1553524	hsa-miR-548ac	CLIP-seq
MIRT1553526	hsa-miR-548d-3p	CLIP-seq
MIRT1553527	hsa-miR-548z	CLIP-seq
MIRT1553528	hsa-miR-571	CLIP-seq
MIRT1338854	hsa-miR-583	CLIP-seq
MIRT2620660	hsa-miR-608	CLIP-seq
MIRT1553533	hsa-miR-625	CLIP-seq
MIRT1553535	hsa-miR-637	CLIP-seq
MIRT1338894	hsa-miR-642b	CLIP-seq
MIRT1553539	hsa-miR-665	CLIP-seq
MIRT1553542	hsa-miR-766	CLIP-seq
MIRT1553543	hsa-miR-939	CLIP-seq

Transcription factors

Show/Hide all(26)

Transcription factor	Regulation	Reference
ARNTL2	Activation	22198637
E2F1	Repression	11402043;11559366
EPAS1	Activation	15039136
ESR1	Activation	15217907
ESR2	Repression	15217907
HIF1A	Unknown	11877282;14567996;17570486
HSF1	Activation	17259369;19401454
KLF10	Activation	12173049
NFKB1	Activation	11757833;12675842
NFKB1	Repression	15631825
NR4A1	Unknown	12506026
PARP1	Activation	22159350
PPARA	Activation	15631825
PPARA	Unknown	12667383
PPARG	Unknown	10073956
RELA	Activation	11757833;12675842
RELA	Repression	15631825
SMAD3	Activation	17761371;24330518;9765209
SMAD3	Unknown	10557285
SMAD4	Activation	9765209
SP1	Activation	15039136
SP1	Unknown	10880342;11251188
SRF	Repression	15514113
TGIF1	Repression	19524896
USF1	Activation	16902162
USF1	Unknown	12235287

Show/Hide all(48)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001525	Process	Angiogenesis	IEP	11866539
GO:0002020	Function	Protease binding	IPI	2503541, 8508955, 8626514, 12114510, 15853774
GO:0002576	Process	Platelet degranulation	TAS
GO:0004867	Function	Serine-type endopeptidase inhibitor activity	IBA	21873635
GO:0004867	Function	Serine-type endopeptidase inhibitor activity	IDA	1695900, 8508955
GO:0005102	Function	Signaling receptor binding	IPI	8626514
GO:0005515	Function	Protein binding	IPI	16272158, 25416956, 28296156, 32296183
GO:0005576	Component	Extracellular region	IDA	9386191
GO:0005576	Component	Extracellular region	TAS
GO:0005615	Component	Extracellular space	IBA	21873635
GO:0005615	Component	Extracellular space	IDA	1695900, 18835034
GO:0005886	Component	Plasma membrane	TAS
GO:0007623	Process	Circadian rhythm	TAS
GO:0010469	Process	Regulation of signaling receptor activity	IDA	8837777
GO:0010757	Process	Negative regulation of plasminogen activation	IDA	8508955
GO:0010757	Process	Negative regulation of plasminogen activation	IMP	18835034, 19855083
GO:0010951	Process	Negative regulation of endopeptidase activity	IBA	21873635
GO:0010951	Process	Negative regulation of endopeptidase activity	IDA	1695900
GO:0014912	Process	Negative regulation of smooth muscle cell migration	IDA	8837777
GO:0030194	Process	Positive regulation of blood coagulation	IMP	9207454
GO:0030195	Process	Negative regulation of blood coagulation	IC	1695900
GO:0030198	Process	Extracellular matrix organization	TAS
GO:0030336	Process	Negative regulation of cell migration	IDA	10902815
GO:0031093	Component	Platelet alpha granule lumen	TAS
GO:0032757	Process	Positive regulation of interleukin-8 production	IMP	19916862
GO:0033629	Process	Negative regulation of cell adhesion mediated by integrin	IDA	8837777
GO:0035491	Process	Positive regulation of leukotriene production involved in inflammatory response	IMP	19916862
GO:0042730	Process	Fibrinolysis	TAS
GO:0045766	Process	Positive regulation of angiogenesis	IMP	18835034
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	TAS
GO:0048260	Process	Positive regulation of receptor-mediated endocytosis	IDA	8626514
GO:0050729	Process	Positive regulation of inflammatory response	IGI	17032919
GO:0050829	Process	Defense response to Gram-negative bacterium	IGI	17032919
GO:0051918	Process	Negative regulation of fibrinolysis	IDA	2503541
GO:0061044	Process	Negative regulation of vascular wound healing	IGI	9386191
GO:0061045	Process	Negative regulation of wound healing	IC	8837777
GO:0062023	Component	Collagen-containing extracellular matrix	HDA	23979707
GO:0062023	Component	Collagen-containing extracellular matrix	HDA	28327460
GO:0062023	Component	Collagen-containing extracellular matrix	IDA	1632457
GO:0070062	Component	Extracellular exosome	IDA	21276792
GO:0071222	Process	Cellular response to lipopolysaccharide	IMP	19916862
GO:0090026	Process	Positive regulation of monocyte chemotaxis	IMP	19916862
GO:0090399	Process	Replicative senescence	IMP	16862142
GO:0097187	Process	Dentinogenesis	IDA	27046084
GO:1901331	Process	Positive regulation of odontoblast differentiation	IDA	27046084
GO:1902042	Process	Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	IMP	18835034
GO:2000098	Process	Negative regulation of smooth muscle cell-matrix adhesion	IDA	8837777
GO:2000352	Process	Negative regulation of endothelial cell apoptotic process	IMP	18835034

MIM	HGNC	e!Ensembl
173360	8583	ENSG00000106366

Protein

UniProt ID

P05121

Protein name

Plasminogen activator inhibitor 1 (PAI) (PAI-1) (Endothelial plasminogen activator inhibitor) (Serpin E1)

Protein function

Serine protease inhibitor. Inhibits TMPRSS7 (PubMed:15853774). Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation

PDB

1A7C , 1B3K , 1C5G , 1DB2 , 1DVM , 1DVN , 1LJ5 , 1OC0 , 3CVM , 3EOX , 3PB1 , 3Q02 , 3Q03 , 3R4L , 3UT3 , 4AQH , 4G8O , 4G8R , 4IC0 , 5BRR , 5ZLZ , 6GWN , 6GWP , 6GWQ , 6I8S , 6ZRV , 7AQF , 7AQG , 9PAI

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00079	Serpin	33 → 402	Serpin (serine protease inhibitor)	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in endothelial cells (PubMed:2430793, PubMed:3097076). Found in plasma, platelets, and hepatoma and fibrosarcoma cells. {ECO:0000269|PubMed:2430793, ECO:0000269|PubMed:3097076}.

Sequence

MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPY
GVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAI
FVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAV
DQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPD
GHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPK
FSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASS
STAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP

Sequence length

402

Interactions

View interactions

	KEGG		Reactome
	HIF-1 signaling pathway p53 signaling pathway Cellular senescence Apelin signaling pathway Hippo signaling pathway Complement and coagulation cascades AGE-RAGE signaling pathway in diabetic complications Chagas disease		Platelet degranulation BMAL1:CLOCK,NPAS2 activates circadian gene expression SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription ECM proteoglycans Dissolution of Fibrin Clot

Show/Hide Causal Diseases (8)

Disease term	Disease name	dbSNP ID	References
Causal
Autism	Autistic Disorder	rs121964908, rs62643608, rs181327458, rs797046134, rs869312704, rs1555013332, rs876657679, rs1057518999, rs1057518658, rs771827120, rs1555187899, rs773080572, rs753871454, rs1684130791, rs1684180699 View all (8 more)	19360663
Behcet syndrome	Behcet Syndrome	rs886040969, rs886039866, rs746055479, rs752615209, rs774164456, rs751454741	12074830
Cholestasis	Cholestasis	rs121909103, rs751511532, rs376368459, rs762702807, rs1578490102, rs1578499691, rs1578504946, rs1317656688, rs199791850, rs1452792080, rs1578491039	21224055
Gastric cancer	Hereditary Diffuse Gastric Cancer	rs137854571, rs63751108, rs34612342, rs121908383, rs121909144, rs121909775, rs121909219, rs121909223, rs63750871, rs80359530, rs121964873, rs121913530, rs606231203, rs121918505, rs587776802 View all (244 more)	16367923
Hypertension	Hypertensive disease	rs13306026	21051829, 22352330
Nephrotic syndrome	Nephrotic Syndrome	rs876657369, rs121912601, rs121912602, rs876657370, rs121912603, rs121912604, rs121912605, rs121907900, rs121907901, rs28941778, rs587776576, rs28942089, rs587776577, rs28941777, rs121907910 View all (152 more)	17513194
Obesity	Obesity	rs74315349, rs1474810899, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562 View all (27 more)	23819014
Prostate cancer	Malignant neoplasm of prostate	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	16172807

Show/Hide Unknown Diseases (7)

Disease term	Disease name	References	Source
Unknown
Atherosclerosis	Atherosclerosis	12677255	ClinVar
Congenital plasminogen activator inhibitor deficiency	Congenital plasminogen activator inhibitor type 1 deficiency		ClinVar
Congestive heart failure	Congestive heart failure	22352330	ClinVar
Heart failure	Heart failure, Left-Sided Heart Failure, Heart Failure, Right-Sided	22352330	ClinVar
Mental depression	Unipolar Depression, Major Depressive Disorder	18794724	ClinVar
Myocardial infarction	Myocardial Failure	22352330	ClinVar
Diabetes	Diabetes		GWAS

Show/Hide Text Mining Associations (420)

Disease Name	Relationship Type	References
Associations from Text Mining
3 Methylglutaconic Aciduria Type I	Stimulate	15158909
Abortion Habitual	Associate	24189965, 24484533, 27504943, 30680517
Abortion Spontaneous	Associate	24189965, 27504943, 29264983, 34360543, 35955896, 38057822
Acidosis Renal Tubular	Associate	37758806
Acute Coronary Syndrome	Stimulate	20061546
Acute Coronary Syndrome	Associate	25788758, 35109843, 40257950
Acute Kidney Injury	Associate	32496420
Acute Lung Injury	Associate	19387177
Adenocarcinoma	Associate	17264880
Adenocarcinoma of Lung	Associate	35710585
Adenoma	Associate	20496126, 23940598
Adenomyosis	Associate	33683668
Aging Premature	Associate	28356730
Agnosia	Associate	16945123
Airway Obstruction	Associate	27713627, 28543872
Airway Remodeling	Associate	25041788
Alzheimer Disease	Associate	26402107, 28466654, 36565112, 40725474
Alzheimer Disease	Stimulate	30775986
Ameloblastoma	Associate	36507758
Amyloidosis	Associate	19033264
Amyotrophic Lateral Sclerosis	Associate	26198021
Anemia Diamond Blackfan	Associate	26258650
Anemia Hemolytic	Associate	12028454
Anemia Sickle Cell	Stimulate	21175428
Aneurysm	Associate	12027469, 14522424
Aneurysm Ascending Aorta	Associate	19580662
Angina Pectoris Variant	Stimulate	8130024
Angina Unstable	Associate	21034162
Antithrombin III Deficiency	Associate	15164384
Aortic Aneurysm Abdominal	Associate	10805895, 12027469, 14522424, 24452721, 7552526
Aortic Aneurysm Familial Abdominal 1	Associate	10805895
Aortic Valve Stenosis	Associate	37408236
Arterial Occlusive Diseases	Associate	14522424
Arteriovenous Fistula	Associate	21332339
Arthritis	Associate	8646430
Arthritis Infectious	Associate	32154187
Arthritis Rheumatoid	Associate	8646430
Ascites	Associate	34614287
Asthma	Associate	10975829, 17765897, 27556405, 28543872, 30707970, 34088958, 36572355
Astrocytoma	Associate	26673168
Ataxia Telangiectasia	Stimulate	32366930
Atherosclerosis	Associate	10751199, 12063175, 12506026, 1495992, 15863881, 17604327, 18065585, 18796547, 19033264, 20558613, 21322770, 22011808, 23089338, 28818858, 29253845, 34741085, 8188696 View all (2 more)
Atherosclerosis	Stimulate	14620928
Atrial Fibrillation	Associate	30518720, 34587750
Atypical Squamous Cells of the Cervix	Associate	29887999
Autism Spectrum Disorder	Associate	19360663
Autism Spectrum Disorder	Stimulate	35113965
Bacteriuria	Associate	17065267
Bile Duct Diseases	Stimulate	19878580
Biliary Atresia	Associate	35774294
Bipolar Disorder	Associate	36878995
Blood Coagulation Disorders	Stimulate	29769125
Blood Coagulation Disorders	Associate	33822421, 37726016, 39729750
Bone Resorption	Associate	25278075
Brain Edema	Associate	31268630
Brain Ischemia	Associate	31268630
Brain Neoplasms	Associate	19336886, 20924077, 33991013
Breast Neoplasms	Associate	10389993, 11021826, 11786417, 12176977, 12556966, 12698185, 16403812, 16945123, 17696882, 19752858, 22467324, 22792263, 23236990, 23803051, 24409301 View all (17 more)
Breast Neoplasms	Inhibit	19400944, 31142059
Bronchopulmonary Dysplasia	Associate	30001393
Budd Chiari Syndrome	Stimulate	19965669
Calcinosis Cutis	Associate	14998856, 19776673, 22552268, 23985164, 37146419
Carcinogenesis	Associate	20549826, 25337248, 34215248, 34997317
Carcinoma Ductal Breast	Associate	14578188
Carcinoma Hepatocellular	Associate	10470287, 27092498, 3026837, 3097076, 31640087, 33960267, 36212175, 36407083, 37181805, 37960718, 37993470, 8387542, 8939896
Carcinoma Hepatocellular	Stimulate	34195849
Carcinoma Intraductal Noninfiltrating	Associate	14578188, 15226768
Carcinoma Non Small Cell Lung	Associate	10811500, 15153803, 29253845
Carcinoma Ovarian Epithelial	Associate	16617562
Carcinoma Pancreatic Ductal	Associate	30539907, 31986125, 32899691
Carcinoma Renal Cell	Associate	15086463, 21129210, 33828127, 34596153, 36959648
Carcinoma Renal Cell	Stimulate	16436671
Carcinoma Squamous Cell	Associate	1918364, 34659450, 37415190, 37746966
Carcinoma Transitional Cell	Associate	20564745
Cardiomyopathies	Stimulate	20392463
Cardiomyopathies	Associate	33432417, 33439236, 39294340
Cardiomyopathy Dilated	Associate	20392463, 30368515, 35662090
Cardiovascular Diseases	Associate	10520809, 11179976, 11733024, 12911596, 15237001, 15575342, 17763167, 20558613, 24497664, 26884864, 30320542, 32125188, 32492148, 36947703
Cardiovascular Diseases	Stimulate	27861608
Carotid Artery Thrombosis	Associate	10803689, 11037896, 12353306
Carotid Stenosis	Associate	22982001
Cataract Age Related Nuclear	Associate	36028501
Cerebral Infarction	Associate	28460568, 29378352, 31013014, 34087973, 34741085, 37175749
Cerebral Palsy	Associate	37726016
Chemical and Drug Induced Liver Injury	Associate	18641190
Cholangiocarcinoma	Inhibit	32212809
Cholangitis Sclerosing	Associate	24390753
Chondrosarcoma	Associate	19734846, 23415961
Choroidal Effusions	Associate	15640330
Chronic Disease	Stimulate	35218958
Chronic Limb Threatening Ischemia	Associate	23770264
Clinical Deterioration	Associate	31268630
Cognition Disorders	Associate	22214620
Cognitive Dysfunction	Stimulate	30775986
Colitis Associated Neoplasms	Associate	22921465
Colitis Ulcerative	Associate	37960728
Colonic Neoplasms	Associate	20931209, 32936304, 34224332, 36221049, 38238555
Colorectal Neoplasms	Associate	12218297, 16091756, 17201153, 17804466, 23626689, 27959430, 29197895, 30581274, 32570732, 32936304, 34215248, 36076991, 36755247, 36941538, 36991138, 37122535, 37986009, 40004552, 7737909 View all (4 more)
Colorectal Neoplasms	Stimulate	38224823
Coma	Associate	31268630
Communication Disorders	Associate	17761618
Constriction Pathologic	Associate	16931622
Corneal Endothelial Cell Loss	Associate	20392463
Coronary Artery Disease	Associate	10803689, 14629464, 22011808, 22990020, 24353175, 25501306, 27805237, 32525847, 39519081
Coronary Artery Disease	Stimulate	26884864, 37175749, 37939716
Coronary Disease	Associate	17604327, 20737565, 22388798, 7892190, 9844142
Coronary Occlusion	Associate	26273123
Coronary Restenosis	Associate	11558839
Coronary Stenosis	Associate	22011808
COVID 19	Associate	33662681, 34003736, 34064104, 35213582, 35532162, 36555850, 37169126, 37924708, 39280271, 39281671
COVID 19	Stimulate	35780481
Coxa Magna	Associate	21752301, 24135164
Cryoglobulinemia Familial Mixed	Associate	33799903
Cystic Fibrosis	Associate	2891140
Cytomegalovirus Infections	Stimulate	19553556
Death	Associate	12027469, 22842942, 37726016
Death	Stimulate	20051950, 21702998
Death	Inhibit	24999729
Dermatitis Atopic 1	Associate	37860000
Diabetes Gestational	Associate	30301460, 34190178, 34930438
Diabetes Gestational	Stimulate	31061324
Diabetes Mellitus	Stimulate	12444310, 30256013
Diabetes Mellitus	Associate	15863881, 16855181, 25966737, 29152572, 30670722, 32633259, 35109843, 37268982, 37758806, 9844142
Diabetes Mellitus Type 2	Associate	10652041, 15575342, 16855181, 20353610, 22577291, 22990020, 23249721, 23304115, 26616527, 28271069, 30669119, 36044519, 36947703
Diabetic Foot	Associate	37380899
Diabetic Foot	Inhibit	38107519
Diabetic Nephropathies	Associate	10652041, 12028454, 15198928, 22629296, 26616527, 35363774, 9844142
Diarrhea 5 With Tufting Enteropathy Congenital	Associate	30937621
Disease	Associate	21079357, 8619400
Disseminated Intravascular Coagulation	Associate	17697137
Drug Hypersensitivity	Associate	38299390
Drug Related Side Effects and Adverse Reactions	Associate	27165605
Dyslipidemias	Associate	22459021, 25788758, 28356730
Dysmenorrhea	Associate	33683668
Emphysematous Cholecystitis	Associate	24479666
Endometrial Hyperplasia	Associate	8989921
Endometrial Neoplasms	Associate	33053339, 33683668, 8989921
Endometriosis	Associate	21306344, 31315131, 33683668
Endotoxemia	Associate	12529760
Enteritis	Associate	15178550
Eosinophilic Esophagitis	Associate	27212082
Epilepsy Temporal Lobe	Associate	30669988
Epileptic Syndromes	Associate	10927066
Erosive Adenomatosis of the Nipple	Associate	22296682
Erythema elevatum diutinum	Inhibit	16014034
Esophageal Neoplasms	Associate	34160902, 36433943
Esophageal Squamous Cell Carcinoma	Associate	15736404, 24833884, 32217514, 33311557, 34404882
Essential Hypertension	Associate	15606380
Familial Mediterranean Fever	Associate	19033264
Fanconi Syndrome	Associate	34110636
Fatty Liver	Associate	37657050
Femur Head Necrosis	Associate	35662090
Fetal Death	Associate	19909951
Fetal Growth Retardation	Associate	26903689
Fetal Growth Retardation	Stimulate	30313110, 8018914
Fibrosarcoma	Associate	12848892, 9933644
Fibrosis	Associate	12675842, 16931622, 21193525, 24141615, 26785615, 27212082, 27967206, 28543872, 28818858, 33245228, 33439236, 33683668, 37758806
Fibrosis	Inhibit	33432417
Gangrene	Associate	33462011
Gastritis	Associate	18519558
Genetic Diseases Inborn	Associate	30256258
Giant Cell Tumor of Bone	Associate	7495280
Glaucoma	Associate	33746571
Glaucoma Open Angle	Stimulate	18615155
Glioblastoma	Associate	10783396, 18819934, 26434837, 30894197, 34761619, 35258403, 35720420, 36159811
Glioma	Associate	16357523, 17855624, 19336886, 26164207, 26673168, 30894197, 33723286, 33947134, 37439825
Gliosarcoma	Associate	7485395
Glomerulonephritis	Associate	16014034, 32921106
Glucose Intolerance	Associate	22459021
Graft vs Host Disease	Stimulate	31300420
Granuloma	Associate	34456926
Granulosa cell tumor of the ovary	Associate	14998856
Hantavirus Infections	Associate	29930915
Hantavirus Pulmonary Syndrome	Associate	29930915
Head and Neck Neoplasms	Associate	26359694, 36510962
Headache	Associate	34254656
Hearing Loss Sensorineural	Associate	15869586
Heart Failure	Associate	30368515
Helicobacter Infections	Stimulate	18519558
Hemangioendothelioma	Associate	25043949, 30256258, 31243110, 33377124
Hemangiosarcoma	Associate	23599148
Hematologic Diseases	Associate	19764075
Hematoma	Associate	9502412
Hemolytic Uremic Syndrome	Stimulate	12675842
Hemorrhage	Associate	12589088, 29378352, 32742523
Hepatic Veno Occlusive Disease	Associate	21330458
Hereditary Angioedema Type III	Associate	31359505
Hyperglycemic Hyperosmolar Nonketotic Coma	Associate	24204837
Hyperhomocysteinemia	Associate	23826780
Hyperinsulinism	Stimulate	17342262
Hyperinsulinism	Associate	8387542
Hyperlipidemias	Associate	23789212
Hyperlipoproteinemia Type II	Stimulate	15840021
Hyperoxia	Stimulate	31411059
Hyperplasia	Associate	27212082
Hypertension	Associate	10652041, 14620928, 15194475, 19401121, 22459021, 25973747, 28271069, 31268630
Hypertension	Stimulate	39595551
Hypertension Pregnancy Induced	Associate	19838007
Hypertriglyceridemia	Associate	28356730
Hypertriglyceridemic Waist	Associate	8548432
Hypoxia	Stimulate	11877282, 12086154, 15328163, 16014034, 17609976, 17663760, 25618585, 29123322, 34456926, 37146419
Hypoxia	Associate	26903689, 32192527, 34249015, 34596153
Hypoxia Brain	Inhibit	16309542
Hypoxia Brain	Stimulate	17663760
Idiopathic Interstitial Pneumonias	Associate	12765340
Idiopathic Pulmonary Fibrosis	Associate	20061390, 32899090, 33214209
Immune System Diseases	Associate	36336725
Immunologic Deficiency Syndromes	Associate	17469143
Infant Newborn Diseases	Associate	23162020
Infarction	Associate	34741085
Infections	Associate	17761618, 19553556, 27556405, 32683889
Inferior Wall Myocardial Infarction	Associate	34741085
Infertility	Associate	21306344, 27855570
Inflammation	Associate	16279946, 19033264, 19855086, 19934269, 22556343, 22952991, 24107402, 24827991, 26268131, 26421388, 27713627, 28356730, 29930915, 31829037, 32154187 View all (11 more)
Inflammation	Stimulate	19916862, 30402041, 32035284
Inflammatory Bowel Diseases	Associate	24496159
Insulin Resistance	Associate	11240843, 14629464, 21959347, 22459021, 23089338, 23871496, 28356730, 33164985, 34554929, 36065507
Insulin Resistance	Stimulate	12444310, 22491740, 26123797, 31612734, 8387542
Intestinal Diseases	Associate	16435385
Intracranial Hemorrhages	Associate	31637872
Intracranial Thrombosis	Associate	17456624, 23222167, 29168367
Invasive Pulmonary Aspergillosis	Associate	22731696
Ischemia	Associate	29378352
Ischemic Attack Transient	Associate	34741085
Keloid	Associate	18832570, 32327724
Kidney Diseases	Associate	10652041, 17469143, 34110636
Kidney Failure Chronic	Associate	23304115
Kidney Neoplasms	Stimulate	33828127
Klinefelter Syndrome	Stimulate	21057745
Klinefelter Syndrome	Associate	30334491
Leiomyoma	Associate	29747655, 37231028
Leiomyosarcoma	Associate	22556343
Leukemia	Associate	33146708
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	35491124, 38103082
Livedoid Vasculopathy	Associate	14620928, 28186689
Liver Cirrhosis	Associate	26785615
Lung Diseases	Associate	12765340, 27713627
Lung Diseases Interstitial	Associate	12765340
Lung Injury	Associate	26663441, 28211612
Lung Neoplasms	Stimulate	10645902
Lung Neoplasms	Associate	12086154, 24175756, 24955483, 26230665, 28211612, 34325549, 9743310
Lupus Erythematosus Systemic	Associate	11260416, 31829037
Lupus Nephritis	Associate	11260416, 17469143, 27716443
Lymphatic Metastasis	Associate	12556966, 23988121, 24833884, 37415190, 7737909
Lymphatic Metastasis	Stimulate	16091756, 25687870, 36959648
Lymphoma Non Hodgkin	Associate	34790823
Macular Degeneration	Associate	35681461
Melanoma	Associate	22716255, 34688409, 36087066, 37838724, 8291613
Melanoma	Stimulate	37481560
Meningioma	Associate	25400818, 26943583
Meningococcal Infections	Associate	17697137, 34273240
Menorrhagia	Associate	10785231
Mental Disorders	Associate	27556405
Mesothelioma	Associate	19855086
Mesothelioma Malignant	Associate	19855086, 7485395
Metabolic Syndrome	Associate	15677734, 19164335, 19619703, 22459021, 22577291, 33059731, 36947703
Metabolic Syndrome	Stimulate	19619703, 28271069
Metrorrhagia	Inhibit	35238278
Microcephaly	Associate	33822234
Mitochondrial Myopathy with a Defect in Mitochondrial Protein Transport	Associate	36028501
Mitral Valve Insufficiency	Associate	33810615
Mouth Diseases	Associate	28186689, 8943484
Mouth Neoplasms	Associate	21549012, 25029526, 36510962
Multiple Myeloma	Associate	20658475, 34774067
Multiple Organ Failure	Associate	20429897
Multiple Sclerosis	Associate	15793294, 31687051, 32192527
Muscular Dystrophy Duchenne	Associate	11204271
Myeloproliferative Disorder Chronic with Eosinophilia	Associate	18563738
Myocardial Infarction	Associate	10971410, 11018023, 14629464, 15119966, 15234427, 16706983, 16998253, 19401121, 21624046, 26273123, 31772617, 33228791, 34273240, 7892190, 8388372
Myocardial Ischemia	Associate	10520809, 33952801
Myopathies Structural Congenital	Stimulate	29253845
Myotonic Dystrophy	Associate	11422656, 31829037
Myotonic Dystrophy	Stimulate	35363774
Nasal Polyps	Associate	36841712
Nasopharyngeal Carcinoma	Associate	38050231
Nausea	Associate	24496159
Neoplasm Invasiveness	Associate	15153803, 32680567
Neoplasm Metastasis	Associate	10692390, 10811500, 11331280, 12556966, 15153803, 16617562, 18519558, 19055748, 20564745, 20797318, 20924077, 20931209, 22552268, 23236396, 23988121 View all (21 more)
Neoplasm Metastasis	Stimulate	16630137, 16945123, 20544684, 22716255, 32344898
Neoplasm Metastasis	Inhibit	7737909
Neoplasm Residual	Associate	36907506
Neoplasms	Associate	10389993, 10692390, 10811500, 10817507, 11021826, 11179976, 11376560, 11733024, 11786417, 12086154, 12218297, 12556966, 12708473, 12743121, 12841684 View all (95 more)
Neoplasms	Inhibit	19400944, 27092498, 27975070
Neoplasms	Stimulate	22921465, 27755560, 32632664, 38393683
Neoplasms Adipose Tissue	Associate	19033264, 19553556, 21959347, 23871496, 33053339, 36233135, 36565112
Neoplasms Germ Cell and Embryonal	Associate	20737565
Neoplasms Glandular and Epithelial	Associate	18469003
Neoplasms Mesothelial	Associate	19855086
Neoplasms Squamous Cell	Associate	15736404
Neuralgia	Associate	29672183
Neuroblastoma	Associate	19147537
Neuroendocrine Tumors	Associate	21193525
Neuroinflammatory Diseases	Associate	32035284
Niemann Pick Disease Type C	Associate	36608914
Non alcoholic Fatty Liver Disease	Associate	18641190, 36407083
Obesity	Associate	16460444, 17898989, 19553556, 20825686, 21911891, 21959347, 22459021, 23089338, 23871496, 25370852, 28356730, 28543872, 29887999, 34273240, 34620218, 36233135, 36572355 View all (2 more)
Obesity	Stimulate	21273999, 21996594, 26123797, 26884864, 31652917, 36835525, 37455922
Osteoarthritis	Associate	20060952
Osteonecrosis	Associate	18285546, 21079357, 23589033, 27356609, 34042331, 34273240, 35662090
Osteoporosis	Associate	32080087
Osteoporotic Fractures	Associate	27941685
Ovarian Diseases	Associate	36336725, 40301911
Ovarian Neoplasms	Associate	12496270, 12743121, 16617562, 17070899, 20797318, 20924077, 23988121, 25587663, 29482638, 32977853, 37621654
Overweight	Stimulate	21996594, 26123797, 26268131
Pancreatic Neoplasms	Associate	15479693, 16547153, 21263190, 22331587, 30539907, 31986125, 34290570
Papillomavirus Infections	Stimulate	36425786
Parkinson Disease	Associate	32035284
Paroxysmal ventricular fibrillation	Associate	32399796
Peptic Ulcer	Associate	12589088, 32742523
Peptic Ulcer Perforation	Associate	32742523
Peripheral Arterial Disease	Associate	15768007, 32633259
Peripheral Vascular Diseases	Associate	11237788, 20737565
Peritonitis	Associate	12743121
Pheochromocytoma	Associate	33828526
Placental Insufficiency	Associate	26903689
Plaque Atherosclerotic	Associate	22982001, 8188696, 8362983
Plasminogen Activator Inhibitor 1 Deficiency	Associate	33439236
Pneumonia	Associate	17761618, 19387177, 20429897
Polycystic Ovary Syndrome	Associate	17661167, 21824047, 21996594, 23898913, 28337819, 34273240
Polycystic Ovary Syndrome	Stimulate	26123797
Polycythemia Vera	Associate	32683889
Polydactyly preaxial 4	Associate	17065267
Post Acute COVID 19 Syndrome	Associate	37924708
Pre Eclampsia	Associate	12716314, 18443340, 26010865, 37545924, 8018914, 8863672
Pre Eclampsia	Stimulate	32898274
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	18285546
Pregnancy Complications	Associate	26903689
Primary Graft Dysfunction	Associate	26663441
Primary Ovarian Insufficiency	Associate	24355042
Progeria	Associate	36028501
Prostatic Neoplasms	Associate	15928670, 24264315, 26944191
Proteinuria	Associate	11260416
Pulmonary Disease Chronic Obstructive	Stimulate	19916862, 27713627
Pulmonary Disease Chronic Obstructive	Associate	27073968, 27856929, 28356730
Pulmonary Edema	Associate	19387177
Pulmonary edema of mountaineers	Associate	26436397
Pulmonary Embolism	Associate	29093435, 36064077
Pulmonary Fibrosis	Associate	12765340
Pulmonary Heart Disease	Associate	24141615
Purpura Thrombocytopenic Idiopathic	Associate	29215956
Radiation Pneumonitis	Associate	28211612, 33109238
Rectal Neoplasms	Associate	19776673
Rectal Neoplasms	Stimulate	32344898
Recurrence	Associate	27504943
Renal Insufficiency	Associate	24189965, 27855570, 31723100
Renal Insufficiency Chronic	Associate	20353610, 22214620
Reperfusion Injury	Associate	37105441
Respiratory Distress Syndrome	Associate	20460339
Respiratory Distress Syndrome Newborn	Associate	20460339
Respiratory Insufficiency	Stimulate	34003736
Respiratory System Abnormalities	Associate	17697137, 27713627
Respiratory Tract Infections	Associate	27556405
Retinal Dysplasia	Stimulate	22921465
Retinal Vein Occlusion	Associate	12353306, 16244763, 19825918, 23222167, 36907506
Rhegmatogenous Retinal Detachment Autosomal Dominant	Associate	29641463
Sarcoma	Associate	17523079, 20051950, 21702998
Sarcoma Synovial	Inhibit	31562358
Schizophrenia	Associate	39940697
Scleroderma Diffuse	Stimulate	20943061
Scleroderma Diffuse	Associate	29858547
Scleroderma Localized	Associate	38324287
Scleroderma Systemic	Associate	24141615
Sclerosis	Associate	12028454
Sepsis	Associate	16444434, 20429897, 22842942
Sepsis	Stimulate	32496420
Severe Acute Respiratory Syndrome	Associate	23589033
Shock Septic	Associate	20429897, 20825686
Sick Sinus Syndrome	Associate	9409572
Sinus Thrombosis Intracranial	Associate	27287941, 34254656
Skin Diseases	Associate	29858547
Sleep Apnea Obstructive	Stimulate	24497664
Sleep Apnea Obstructive	Associate	27861608, 35887329
Squamous Cell Carcinoma of Head and Neck	Associate	24999729, 25268377, 25337248, 26359694, 30431092, 30589034, 30937621, 31562292, 31927533, 32623386, 33820852, 34502382, 34599215, 35409173, 35432823 View all (6 more)
ST Elevation Myocardial Infarction	Associate	19401121, 21624046
Status Asthmaticus	Associate	10975829, 21478212, 27556405, 30707970, 37860000
Status Asthmaticus	Stimulate	33245228, 34088958
Stomach Neoplasms	Associate	16435385, 16630137, 18381294, 20549826, 25687870, 31127138, 31747387, 32908579, 33754626, 33780362, 34249015, 35691615, 35954218, 36697459, 37100457 View all (5 more)
Stomach Neoplasms	Stimulate	39527470
Stomach Ulcer	Associate	12589088
Stroke	Associate	10971410, 24189452, 28460568, 34087973, 36315566, 37175749
Subarachnoid Hemorrhage	Associate	16998253, 31268630
Tachycardia Atrioventricular Nodal Reentry	Associate	12556966
Takayasu Arteritis	Associate	34523592
Temporomandibular Joint Dysfunction Syndrome	Associate	31340134
Tertiary Lymphoid Structures	Stimulate	16630137
Tertiary Lymphoid Structures	Associate	16945123
Testicular Neoplasms	Associate	20737565
Thrombocythemia Essential	Associate	25989112
Thrombocytopenia	Associate	32683889
Thromboembolism	Associate	20724304, 2891140
Thrombophilia	Associate	11091191, 14653439, 15678268, 19909951, 23324841, 24569626, 27223647, 27855570, 34360543, 34523592, 37241083
Thrombophilia hereditary	Associate	14653439
Thrombosis	Associate	10381497, 10577569, 10751199, 11037896, 12028454, 12218992, 12353306, 1309426, 14653439, 15164384, 16846490, 16931622, 18285546, 20558613, 20724304 View all (19 more)
Thrombosis	Inhibit	11122093, 11786505, 36044519
Thrombosis	Stimulate	30518720
Thrombotic Microangiopathies	Stimulate	8943484
Thrombotic Stroke	Associate	23162020
Thyroid Carcinoma Anaplastic	Associate	40157360
Thyroid Neoplasms	Associate	40157360
Tissue Adhesions	Associate	37385390
Triple Negative Breast Neoplasms	Associate	27286449, 34997317
Trophoblastic Neoplasms	Associate	8863672
Tumor Lysis Syndrome	Associate	31637872, 37201530
Ulcer	Associate	22565455, 28186689
Urinary Bladder Neoplasms	Associate	20564745, 22108519, 25387487, 35842542, 36902377
Uterine Cervical Neoplasms	Associate	23873179
Uterine Cervical Neoplasms	Stimulate	37580647
Varicose Ulcer	Associate	20724304, 21057745, 22565455
Varicose Ulcer	Stimulate	27994710
Vascular Diseases	Associate	10722838, 11786505, 12506026, 16855181, 24435163, 28460568, 30402041, 34003736, 39281671, 8188696
Vasospasm Intracranial	Associate	31268630
Venous Insufficiency	Associate	20926026
Venous Thromboembolism	Associate	18160588, 20737565, 31827635, 34325549, 35255511, 39729750
Venous Thrombosis	Associate	11091191, 12643326, 1391943, 14653439, 19419975, 22565455, 22952991, 24715181, 27287941, 29321050, 30334491, 34273240, 36907506, 37951941
von Hippel Lindau Disease	Associate	33828526
Weight Loss	Associate	20102484, 24141897
Werner Syndrome	Stimulate	18312663
Wieacker syndrome	Inhibit	27070589
Wolfram Like Syndrome Autosomal Dominant	Associate	21624046
Wounds and Injuries	Associate	12027469, 33439236

SERPINE1 (serpin family E member 1)