G0S2 (G0/G1 switch 2)

Gene
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
50486
Gene name Gene Name - the full gene name approved by the HGNC.
G0/G1 switch 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
G0S2
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1q32.2
Transcription factors
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(2)
Transcription factor Regulation Reference
NCOR1 Repression 23098689
PPARA Unknown 20110263
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(10)
GO ID Ontology Definition Evidence Reference
GO:0003674 Function Molecular_function ND
GO:0005515 Function Protein binding IPI 19706769, 32296183
GO:0005739 Component Mitochondrion IBA 21873635
GO:0005739 Component Mitochondrion IDA 19706769
GO:0005811 Component Lipid droplet TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
614447 30229 ENSG00000123689
Protein
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID P27469
Protein name G0/G1 switch protein 2 (G0/G1 switch regulatory protein 2) (Putative lymphocyte G0/G1 switch gene)
Protein function Promotes apoptosis by binding to BCL2, hence preventing the formation of protective BCL2-BAX heterodimers.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15103 G0-G1_switch_2 1 → 103 G0/G1 switch protein 2 Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed with highest levels in peripheral blood, skeletal muscle and heart, followed by kidney and liver. {ECO:0000269|PubMed:19706769}.
Sequence
Sequence length 103
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
  Reactome
    PPARA activates gene expression
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Carcinoma Carcinoma, Carcinoma, Spindle-Cell, Undifferentiated carcinoma rs121912654, rs555607708, rs786202962, rs1564055259 16316942
Show/Hide Text Mining Associations (38)
Associations from Text Mining
Disease Name Relationship Type References
Adenoma Associate 30175151
Adrenocortical Carcinoma Associate 30770352
Arthritis Rheumatoid Associate 17082220
Asthma Associate 33878997, 35501805
Autoimmune Diseases Stimulate 22771791
Brain Ischemia Associate 38049739
Carcinogenesis Associate 29073263
Carcinoma Non Small Cell Lung Associate 26318046
Carcinoma Squamous Cell Associate 29073263
Cerebral Arterial Diseases Associate 38049739