PAEP (progestagen associated endometrial protein)

Gene
Gene Transcription factors Gene ontology Other IDs Protein
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
5047
Gene name Gene Name - the full gene name approved by the HGNC.
Progestagen associated endometrial protein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PAEP
Synonyms (NCBI Gene) Gene synonyms aliases
GD, GdA, GdF, GdS, PAEG, PEP, PP14, ZIF-1
Chromosome Chromosome number
9
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
9q34.3
Summary Summary of gene provided in NCBI Entrez Gene.
This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromo
Transcription factors
Gene Transcription factors Gene ontology Other IDs Protein
Show/Hide all(1)
Transcription factor Regulation Reference
GATA3 Activation 19483726
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Transcription factors Gene ontology Other IDs Protein
Show/Hide all(8)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956, 29892012, 31515488, 32296183
GO:0005576 Component Extracellular region IDA 3667877, 12672671
GO:0005576 Component Extracellular region IEA
GO:0006915 Process Apoptotic process IDA 18996219
GO:0032725 Process Positive regulation of granulocyte macrophage colony-stimulating factor production IDA 19945098
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Transcription factors Gene ontology Other IDs Protein
MIM HGNC e!Ensembl
173310 8573 ENSG00000122133
Protein
Gene Transcription factors Gene ontology Other IDs Protein
UniProt ID P09466
Protein name Glycodelin (GD) (Placental protein 14) (PP14) (Pregnancy-associated endometrial alpha-2 globulin) (PAEG) (PEG) (Progestagen-associated endometrial protein) (Progesterone-associated endometrial protein) (Zona-binding inhibitory factor-1) (ZIF-1)
Protein function Glycoprotein that regulates critical steps during fertilization and also has immunomonomodulatory effects. Four glycoforms, namely glycodelin-S, -A, -F and -C have been identified in reproductive tissues that differ in glycosylation and biologic
PDB 4R0B
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00061 Lipocalin 34 → 175 Lipocalin / cytosolic fatty-acid binding protein family Domain
Tissue specificity TISSUE SPECIFICITY: This protein is, the main protein synthesized and secreted in the endometrium from mid-luteal phase of the menstrual cycle and during the first semester of pregnancy (PubMed:3667877). Glycodelin-A is expressed in amniotic fluid, endome
Sequence
Sequence length 180
Interactions View interactions
<