PEBP1 (phosphatidylethanolamine binding protein 1)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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5037 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Phosphatidylethanolamine binding protein 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PEBP1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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HCNP, HCNPpp, HEL-210, HEL-S-34, HEL-S-96, PBP, PEBP, PEBP-1, RKIP |
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Chromosome
Chromosome number
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12 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12q24.23 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the phosphatidylethanolamine-binding family of proteins and has been shown to modulate multiple signaling pathways, including the MAP kinase (MAPK), NF-kappa B, and glycogen synthase kinase-3 (GSK-3) signaling pathways. The e |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | P30086 | ||||||||||
| Protein name | Phosphatidylethanolamine-binding protein 1 (PEBP-1) (HCNPpp) (Neuropolypeptide h3) (Prostatic-binding protein) (Raf kinase inhibitor protein) (RKIP) [Cleaved into: Hippocampal cholinergic neurostimulating peptide (HCNP)] | ||||||||||
| Protein function | Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activato | ||||||||||
| PDB | 1BD9 , 1BEH , 2L7W , 2QYQ | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 187 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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