PA2G4 (proliferation-associated 2G4)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 5036 |
| Gene name | Proliferation-associated 2G4 |
| Gene symbol | PA2G4 |
| Synonyms (NCBI Gene) |
EBP1HG4-1ITAF45p38-2G4
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| Chromosome | 12 |
| Chromosome location | 12q13.2 |
| Summary | This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA process |
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miRNA
miRNA information provided by mirtarbase database.
381
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9UQ80 | ||||||||||
| Protein name | Proliferation-associated protein 2G4 (Cell cycle protein p38-2G4 homolog) (hG4-1) (ErbB3-binding protein 1) | ||||||||||
| Protein function | May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription | ||||||||||
| PDB | 2Q8K , 3J2I , 6CHT , 6LSR , 6SXO , 6WM8 , 6Z6L , 6Z6M , 6Z6N , 6ZM7 , 6ZME , 6ZMI , 6ZMO , 7BHP , 8K2C , 8XSX , 8XSY , 8XSZ | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Isoform 2 is undetectable whereas isoform 1 is strongly expressed in cancer cells (at protein level). Isoform 1 and isoform 2 are widely expressed, including heart, brain, lung, pancreas, skeletal muscle, kidney, placenta and liver. {E | ||||||||||
| Sequence |
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| Sequence length | 394 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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