ORM1 (orosomucoid 1)

Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
5004
Gene name Gene Name - the full gene name approved by the HGNC.
Orosomucoid 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ORM1
Synonyms (NCBI Gene) Gene synonyms aliases
A1AG1, AGP-A, AGP1, HEL-S-153w, ORM
Chromosome Chromosome number
9
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
9q32
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(1)
miRTarBase ID miRNA Experiments Reference
MIRT734893 hsa-miR-362-3p Luciferase reporter assay, Western blotting, qRT-PCR 33459949
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(23)
GO ID Ontology Definition Evidence Reference
GO:0002576 Process Platelet degranulation TAS
GO:0002682 Process Regulation of immune system process IEA
GO:0005515 Function Protein binding IPI 16272158
GO:0005576 Component Extracellular region HDA 27068509
GO:0005576 Component Extracellular region NAS 14718574
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
138600 8498 ENSG00000229314
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID P02763
Protein name Alpha-1-acid glycoprotein 1 (AGP 1) (Orosomucoid-1) (OMD 1)
Protein function Functions as a transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating t
PDB 3KQ0
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00061 Lipocalin 40 → 180 Lipocalin / cytosolic fatty-acid binding protein family Domain
Tissue specificity TISSUE SPECIFICITY: Expressed by the liver and secreted in plasma.
Sequence
Sequence length 201
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
  Reactome
    Platelet degranulation
Neutrophil degranulation
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Liver failure Liver Failure rs118203990, rs118203991, rs118203992, rs387907022, rs201861847, rs796065037, rs759315662, rs368196005, rs796052121, rs369437593, rs367683258, rs766314948, rs368085185, rs770446752, rs753039116
View all (10 more)		 18256743
Show/Hide Text Mining Associations (51)
Associations from Text Mining
Disease Name Relationship Type References
Acute Coronary Syndrome Associate 34002800
Adenoma Liver Cell Associate 34963738
Alzheimer Disease Associate 40471493
Arthritis Rheumatoid Stimulate 26915672
Arthritis Rheumatoid Associate 35603148
Asthma Associate 20182505
Atherosclerosis Associate 24526693
Breast Neoplasms Stimulate 34654351
Breast Neoplasms Associate 35188865
Carcinogenesis Associate 35765957