Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
494324
Gene name Gene Name - the full gene name approved by the HGNC.
MicroRNA 375
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MIR375
Synonyms (NCBI Gene) Gene synonyms aliases
MIRN375, hsa-mir-375, miRNA375, mir-375
Chromosome Chromosome number
2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2q35
Summary Summary of gene provided in NCBI Entrez Gene.
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT737054 hsa-miR-375 Luciferase reporter assay, Western blotting, Immunohistochemistry (IHC), qRT-PCR 31802830
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005615 Component Extracellular space HDA 26646931
GO:0016442 Component RISC complex IEA
GO:0035195 Process MiRNA-mediated post-transcriptional gene silencing IEA
GO:0051898 Process Negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction ISS
GO:1903671 Process Negative regulation of sprouting angiogenesis IGI 26235810
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
611173 31868 ENSG00000198973
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  MicroRNAs in cancer  
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Diabetes Type 2 diabetes (adjusted for BMI), Type 2 diabetes, Type 2 diabetes mellitus adjusted for BMI or coronary artery disease (pleiotropy) N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Adenocarcinoma Stimulate 19789312, 26642205
Adenocarcinoma Associate 22302717, 23466817, 24625834, 25695220, 33866108, 37686123
Adenocarcinoma of Lung Associate 21351266, 29932500, 30621620, 31983094, 32965722, 35984198, 37801008
Adenocarcinoma of Lung Stimulate 28533502
Adenoma Inhibit 30258124
Alzheimer Disease Associate 25992776
Asthma Inhibit 32308108
Asthma Associate 36000159
Barrett Esophagus Inhibit 19789312
Barrett Esophagus Associate 23466817