Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	490
Gene name	ATPase plasma membrane Ca2+ transporting 1
Gene symbol	ATP2B1
Synonyms (NCBI Gene)	MRD66PMCA1PMCA1kb
Chromosome	12
Chromosome location	12q21.33
Summary	The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells

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miRTarBase ID	miRNA	Experiments	Reference
MIRT005818	hsa-miR-204-5p	Microarray	21282569
MIRT052579	hsa-let-7a-5p	CLASH	23622248
MIRT039645	hsa-miR-615-3p	CLASH	23622248
MIRT724532	hsa-miR-483-3p	HITS-CLIP	19536157
MIRT136414	hsa-miR-6892-3p	HITS-CLIP	19536157
MIRT724531	hsa-miR-2276-5p	HITS-CLIP	19536157
MIRT724530	hsa-miR-3183	HITS-CLIP	19536157
MIRT724529	hsa-miR-4723-3p	HITS-CLIP	19536157
MIRT724528	hsa-miR-6769b-3p	HITS-CLIP	19536157
MIRT136366	hsa-miR-150-5p	HITS-CLIP	19536157
MIRT724527	hsa-miR-532-3p	HITS-CLIP	19536157
MIRT724526	hsa-miR-2116-3p	HITS-CLIP	19536157
MIRT724525	hsa-miR-4469	HITS-CLIP	19536157
MIRT724524	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT384907	hsa-miR-7110-3p	HITS-CLIP	19536157
MIRT384905	hsa-miR-6817-3p	HITS-CLIP	19536157
MIRT724523	hsa-miR-642a-5p	HITS-CLIP	19536157
MIRT724522	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT136399	hsa-miR-4713-5p	HITS-CLIP	19536157
MIRT384906	hsa-miR-6873-3p	HITS-CLIP	19536157
MIRT561127	hsa-miR-4282	PAR-CLIP	20371350
MIRT561128	hsa-miR-3606-3p	PAR-CLIP	20371350
MIRT561126	hsa-miR-513a-3p	PAR-CLIP	20371350
MIRT561125	hsa-miR-513c-3p	PAR-CLIP	20371350
MIRT561124	hsa-miR-5697	PAR-CLIP	20371350
MIRT561123	hsa-miR-1297	PAR-CLIP	20371350
MIRT561122	hsa-miR-26a-5p	PAR-CLIP	20371350
MIRT561121	hsa-miR-26b-5p	PAR-CLIP	20371350
MIRT561119	hsa-miR-4465	PAR-CLIP	20371350
MIRT561120	hsa-miR-498	PAR-CLIP	20371350
MIRT441151	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT441152	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT441150	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT441151	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT441152	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT728259	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT728258	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT728257	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT728255	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT728256	hsa-miR-181a-5p	HITS-CLIP	22473208
MIRT728254	hsa-miR-181b-5p	HITS-CLIP	22473208
MIRT728253	hsa-miR-181c-5p	HITS-CLIP	22473208
MIRT728252	hsa-miR-181d-5p	HITS-CLIP	22473208
MIRT441150	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT724532	hsa-miR-483-3p	HITS-CLIP	19536157
MIRT136414	hsa-miR-6892-3p	HITS-CLIP	19536157
MIRT724531	hsa-miR-2276-5p	HITS-CLIP	19536157
MIRT724530	hsa-miR-3183	HITS-CLIP	19536157
MIRT724529	hsa-miR-4723-3p	HITS-CLIP	19536157
MIRT724528	hsa-miR-6769b-3p	HITS-CLIP	19536157
MIRT136366	hsa-miR-150-5p	HITS-CLIP	19536157
MIRT724527	hsa-miR-532-3p	HITS-CLIP	19536157
MIRT724526	hsa-miR-2116-3p	HITS-CLIP	19536157
MIRT724525	hsa-miR-4469	HITS-CLIP	19536157
MIRT724524	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT384907	hsa-miR-7110-3p	HITS-CLIP	19536157
MIRT384905	hsa-miR-6817-3p	HITS-CLIP	19536157
MIRT724523	hsa-miR-642a-5p	HITS-CLIP	19536157
MIRT724522	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT136399	hsa-miR-4713-5p	HITS-CLIP	19536157
MIRT384906	hsa-miR-6873-3p	HITS-CLIP	19536157
MIRT561127	hsa-miR-4282	PAR-CLIP	20371350
MIRT561128	hsa-miR-3606-3p	PAR-CLIP	20371350
MIRT561126	hsa-miR-513a-3p	PAR-CLIP	20371350
MIRT561125	hsa-miR-513c-3p	PAR-CLIP	20371350
MIRT561124	hsa-miR-5697	PAR-CLIP	20371350
MIRT561123	hsa-miR-1297	PAR-CLIP	20371350
MIRT561122	hsa-miR-26a-5p	PAR-CLIP	20371350
MIRT561121	hsa-miR-26b-5p	PAR-CLIP	20371350
MIRT561119	hsa-miR-4465	PAR-CLIP	20371350
MIRT561120	hsa-miR-498	PAR-CLIP	20371350
MIRT807482	hsa-miR-106a	CLIP-seq
MIRT807483	hsa-miR-106b	CLIP-seq
MIRT807484	hsa-miR-1185	CLIP-seq
MIRT807485	hsa-miR-1197	CLIP-seq
MIRT807486	hsa-miR-1208	CLIP-seq
MIRT807487	hsa-miR-1224-3p	CLIP-seq
MIRT807488	hsa-miR-1225-5p	CLIP-seq
MIRT807489	hsa-miR-1260	CLIP-seq
MIRT807490	hsa-miR-1260b	CLIP-seq
MIRT807491	hsa-miR-1264	CLIP-seq
MIRT807492	hsa-miR-1267	CLIP-seq
MIRT807493	hsa-miR-1279	CLIP-seq
MIRT807494	hsa-miR-128	CLIP-seq
MIRT807495	hsa-miR-1280	CLIP-seq
MIRT807496	hsa-miR-129-5p	CLIP-seq
MIRT807497	hsa-miR-1301	CLIP-seq
MIRT807498	hsa-miR-130a	CLIP-seq
MIRT807499	hsa-miR-130b	CLIP-seq
MIRT807500	hsa-miR-150	CLIP-seq
MIRT807501	hsa-miR-17	CLIP-seq
MIRT807502	hsa-miR-181a	CLIP-seq
MIRT807503	hsa-miR-181b	CLIP-seq
MIRT807504	hsa-miR-181c	CLIP-seq
MIRT807505	hsa-miR-181d	CLIP-seq
MIRT807506	hsa-miR-197	CLIP-seq
MIRT807507	hsa-miR-203	CLIP-seq
MIRT807508	hsa-miR-2052	CLIP-seq
MIRT807509	hsa-miR-20a	CLIP-seq
MIRT807510	hsa-miR-20b	CLIP-seq
MIRT807511	hsa-miR-216a	CLIP-seq
MIRT807512	hsa-miR-216b	CLIP-seq
MIRT807513	hsa-miR-223	CLIP-seq
MIRT807514	hsa-miR-27a	CLIP-seq
MIRT807515	hsa-miR-27b	CLIP-seq
MIRT807516	hsa-miR-301a	CLIP-seq
MIRT807517	hsa-miR-301b	CLIP-seq
MIRT807518	hsa-miR-3117-3p	CLIP-seq
MIRT807519	hsa-miR-3130-5p	CLIP-seq
MIRT807520	hsa-miR-3152-3p	CLIP-seq
MIRT807521	hsa-miR-3152-5p	CLIP-seq
MIRT807522	hsa-miR-3169	CLIP-seq
MIRT807523	hsa-miR-3187-3p	CLIP-seq
MIRT807524	hsa-miR-3194-3p	CLIP-seq
MIRT807525	hsa-miR-320a	CLIP-seq
MIRT807526	hsa-miR-320b	CLIP-seq
MIRT807527	hsa-miR-320c	CLIP-seq
MIRT807528	hsa-miR-320d	CLIP-seq
MIRT807529	hsa-miR-338-5p	CLIP-seq
MIRT807530	hsa-miR-340	CLIP-seq
MIRT807531	hsa-miR-34c-3p	CLIP-seq
MIRT807532	hsa-miR-3591-3p	CLIP-seq
MIRT807533	hsa-miR-3605-5p	CLIP-seq
MIRT807534	hsa-miR-3616-5p	CLIP-seq
MIRT807535	hsa-miR-3617	CLIP-seq
MIRT807536	hsa-miR-3619-3p	CLIP-seq
MIRT807537	hsa-miR-3647-3p	CLIP-seq
MIRT807538	hsa-miR-3647-5p	CLIP-seq
MIRT807539	hsa-miR-3653	CLIP-seq
MIRT807540	hsa-miR-3658	CLIP-seq
MIRT807541	hsa-miR-3666	CLIP-seq
MIRT807542	hsa-miR-3667-5p	CLIP-seq
MIRT807543	hsa-miR-3675-5p	CLIP-seq
MIRT807544	hsa-miR-3679-5p	CLIP-seq
MIRT807545	hsa-miR-374c	CLIP-seq
MIRT807546	hsa-miR-380	CLIP-seq
MIRT807547	hsa-miR-3913-3p	CLIP-seq
MIRT807548	hsa-miR-3920	CLIP-seq
MIRT807549	hsa-miR-3973	CLIP-seq
MIRT807550	hsa-miR-4262	CLIP-seq
MIRT807551	hsa-miR-4263	CLIP-seq
MIRT807552	hsa-miR-4277	CLIP-seq
MIRT807553	hsa-miR-4283	CLIP-seq
MIRT807554	hsa-miR-4293	CLIP-seq
MIRT807555	hsa-miR-4295	CLIP-seq
MIRT807556	hsa-miR-4307	CLIP-seq
MIRT807557	hsa-miR-4317	CLIP-seq
MIRT807558	hsa-miR-4429	CLIP-seq
MIRT807559	hsa-miR-4435	CLIP-seq
MIRT807560	hsa-miR-4436a	CLIP-seq
MIRT807561	hsa-miR-4453	CLIP-seq
MIRT807562	hsa-miR-4477a	CLIP-seq
MIRT807563	hsa-miR-4482	CLIP-seq
MIRT807564	hsa-miR-4489	CLIP-seq
MIRT807565	hsa-miR-4501	CLIP-seq
MIRT807566	hsa-miR-4502	CLIP-seq
MIRT807567	hsa-miR-4503	CLIP-seq
MIRT807568	hsa-miR-4509	CLIP-seq
MIRT807569	hsa-miR-452	CLIP-seq
MIRT807570	hsa-miR-4538	CLIP-seq
MIRT807571	hsa-miR-454	CLIP-seq
MIRT807572	hsa-miR-4635	CLIP-seq
MIRT807573	hsa-miR-4652-3p	CLIP-seq
MIRT807574	hsa-miR-4660	CLIP-seq
MIRT807575	hsa-miR-4661-5p	CLIP-seq
MIRT807576	hsa-miR-4675	CLIP-seq
MIRT807577	hsa-miR-4676-3p	CLIP-seq
MIRT807578	hsa-miR-4687-3p	CLIP-seq
MIRT807579	hsa-miR-4693-5p	CLIP-seq
MIRT807580	hsa-miR-4697-3p	CLIP-seq
MIRT807581	hsa-miR-4699-3p	CLIP-seq
MIRT807582	hsa-miR-4701-5p	CLIP-seq
MIRT807583	hsa-miR-4729	CLIP-seq
MIRT807584	hsa-miR-4740-5p	CLIP-seq
MIRT807585	hsa-miR-4741	CLIP-seq
MIRT807586	hsa-miR-4744	CLIP-seq
MIRT807587	hsa-miR-4773	CLIP-seq
MIRT807588	hsa-miR-4774-3p	CLIP-seq
MIRT807589	hsa-miR-4775	CLIP-seq
MIRT807590	hsa-miR-4799-5p	CLIP-seq
MIRT807591	hsa-miR-4803	CLIP-seq
MIRT807592	hsa-miR-499-3p	CLIP-seq
MIRT807593	hsa-miR-499a-3p	CLIP-seq
MIRT807594	hsa-miR-5047	CLIP-seq
MIRT807595	hsa-miR-518a-3p	CLIP-seq
MIRT807596	hsa-miR-518b	CLIP-seq
MIRT807597	hsa-miR-518c	CLIP-seq
MIRT807598	hsa-miR-518d-3p	CLIP-seq
MIRT807599	hsa-miR-518f	CLIP-seq
MIRT807600	hsa-miR-519a	CLIP-seq
MIRT807601	hsa-miR-519b-3p	CLIP-seq
MIRT807602	hsa-miR-519c-3p	CLIP-seq
MIRT807603	hsa-miR-519d	CLIP-seq
MIRT807604	hsa-miR-520g	CLIP-seq
MIRT807605	hsa-miR-520h	CLIP-seq
MIRT807606	hsa-miR-544b	CLIP-seq
MIRT807607	hsa-miR-548c-3p	CLIP-seq
MIRT807608	hsa-miR-548s	CLIP-seq
MIRT807609	hsa-miR-548u	CLIP-seq
MIRT807610	hsa-miR-571	CLIP-seq
MIRT807611	hsa-miR-573	CLIP-seq
MIRT807612	hsa-miR-576-5p	CLIP-seq
MIRT807613	hsa-miR-577	CLIP-seq
MIRT807614	hsa-miR-579	CLIP-seq
MIRT807615	hsa-miR-582-5p	CLIP-seq
MIRT807616	hsa-miR-588	CLIP-seq
MIRT807617	hsa-miR-591	CLIP-seq
MIRT807618	hsa-miR-641	CLIP-seq
MIRT807619	hsa-miR-648	CLIP-seq
MIRT807620	hsa-miR-653	CLIP-seq
MIRT807621	hsa-miR-655	CLIP-seq
MIRT807622	hsa-miR-767-3p	CLIP-seq
MIRT807623	hsa-miR-93	CLIP-seq
MIRT807624	hsa-miR-944	CLIP-seq
MIRT807487	hsa-miR-1224-3p	CLIP-seq
MIRT807488	hsa-miR-1225-5p	CLIP-seq
MIRT807489	hsa-miR-1260	CLIP-seq
MIRT807490	hsa-miR-1260b	CLIP-seq
MIRT807495	hsa-miR-1280	CLIP-seq
MIRT1938455	hsa-miR-1299	CLIP-seq
MIRT1938456	hsa-miR-144	CLIP-seq
MIRT807500	hsa-miR-150	CLIP-seq
MIRT1938457	hsa-miR-155	CLIP-seq
MIRT807513	hsa-miR-223	CLIP-seq
MIRT807521	hsa-miR-3152-5p	CLIP-seq
MIRT807524	hsa-miR-3194-3p	CLIP-seq
MIRT807529	hsa-miR-338-5p	CLIP-seq
MIRT807532	hsa-miR-3591-3p	CLIP-seq
MIRT807537	hsa-miR-3647-3p	CLIP-seq
MIRT1938458	hsa-miR-3682-3p	CLIP-seq
MIRT807548	hsa-miR-3920	CLIP-seq
MIRT1938459	hsa-miR-4264	CLIP-seq
MIRT807552	hsa-miR-4277	CLIP-seq
MIRT1938460	hsa-miR-431	CLIP-seq
MIRT1938461	hsa-miR-4424	CLIP-seq
MIRT1938462	hsa-miR-4452	CLIP-seq
MIRT807562	hsa-miR-4477a	CLIP-seq
MIRT807566	hsa-miR-4502	CLIP-seq
MIRT807569	hsa-miR-452	CLIP-seq
MIRT807575	hsa-miR-4661-5p	CLIP-seq
MIRT807577	hsa-miR-4676-3p	CLIP-seq
MIRT1938463	hsa-miR-4682	CLIP-seq
MIRT807579	hsa-miR-4693-5p	CLIP-seq
MIRT807580	hsa-miR-4697-3p	CLIP-seq
MIRT1938464	hsa-miR-4703-3p	CLIP-seq
MIRT1938465	hsa-miR-4711-5p	CLIP-seq
MIRT1938466	hsa-miR-4768-5p	CLIP-seq
MIRT807587	hsa-miR-4773	CLIP-seq
MIRT807588	hsa-miR-4774-3p	CLIP-seq
MIRT807589	hsa-miR-4775	CLIP-seq
MIRT807614	hsa-miR-579	CLIP-seq
MIRT807615	hsa-miR-582-5p	CLIP-seq
MIRT1938467	hsa-miR-590-3p	CLIP-seq
MIRT1938468	hsa-miR-640	CLIP-seq
MIRT1938469	hsa-miR-875-3p	CLIP-seq
MIRT1938470	hsa-miR-922	CLIP-seq
MIRT1938471	hsa-miR-935	CLIP-seq
MIRT807624	hsa-miR-944	CLIP-seq
MIRT2177812	hsa-miR-103a	CLIP-seq
MIRT807482	hsa-miR-106a	CLIP-seq
MIRT807483	hsa-miR-106b	CLIP-seq
MIRT2177813	hsa-miR-107	CLIP-seq
MIRT807485	hsa-miR-1197	CLIP-seq
MIRT807486	hsa-miR-1208	CLIP-seq
MIRT807487	hsa-miR-1224-3p	CLIP-seq
MIRT807488	hsa-miR-1225-5p	CLIP-seq
MIRT807489	hsa-miR-1260	CLIP-seq
MIRT807490	hsa-miR-1260b	CLIP-seq
MIRT807491	hsa-miR-1264	CLIP-seq
MIRT807494	hsa-miR-128	CLIP-seq
MIRT807495	hsa-miR-1280	CLIP-seq
MIRT2177814	hsa-miR-1283	CLIP-seq
MIRT1938455	hsa-miR-1299	CLIP-seq
MIRT807498	hsa-miR-130a	CLIP-seq
MIRT807499	hsa-miR-130b	CLIP-seq
MIRT2177815	hsa-miR-1323	CLIP-seq
MIRT2177816	hsa-miR-137	CLIP-seq
MIRT807500	hsa-miR-150	CLIP-seq
MIRT1938457	hsa-miR-155	CLIP-seq
MIRT807501	hsa-miR-17	CLIP-seq
MIRT807506	hsa-miR-197	CLIP-seq
MIRT807509	hsa-miR-20a	CLIP-seq
MIRT807510	hsa-miR-20b	CLIP-seq
MIRT807513	hsa-miR-223	CLIP-seq
MIRT2177817	hsa-miR-25	CLIP-seq
MIRT807514	hsa-miR-27a	CLIP-seq
MIRT807515	hsa-miR-27b	CLIP-seq
MIRT807516	hsa-miR-301a	CLIP-seq
MIRT807517	hsa-miR-301b	CLIP-seq
MIRT2177818	hsa-miR-3065-3p	CLIP-seq
MIRT2177819	hsa-miR-3074-3p	CLIP-seq
MIRT2177820	hsa-miR-30a	CLIP-seq
MIRT2177821	hsa-miR-30b	CLIP-seq
MIRT2177822	hsa-miR-30c	CLIP-seq
MIRT2177823	hsa-miR-30d	CLIP-seq
MIRT2177824	hsa-miR-30e	CLIP-seq
MIRT807518	hsa-miR-3117-3p	CLIP-seq
MIRT2177825	hsa-miR-3129-3p	CLIP-seq
MIRT807519	hsa-miR-3130-5p	CLIP-seq
MIRT807524	hsa-miR-3194-3p	CLIP-seq
MIRT2177826	hsa-miR-32	CLIP-seq
MIRT807529	hsa-miR-338-5p	CLIP-seq
MIRT807531	hsa-miR-34c-3p	CLIP-seq
MIRT807534	hsa-miR-3616-5p	CLIP-seq
MIRT807535	hsa-miR-3617	CLIP-seq
MIRT807536	hsa-miR-3619-3p	CLIP-seq
MIRT2177827	hsa-miR-363	CLIP-seq
MIRT807538	hsa-miR-3647-5p	CLIP-seq
MIRT807541	hsa-miR-3666	CLIP-seq
MIRT807542	hsa-miR-3667-5p	CLIP-seq
MIRT2177828	hsa-miR-367	CLIP-seq
MIRT807545	hsa-miR-374c	CLIP-seq
MIRT807547	hsa-miR-3913-3p	CLIP-seq
MIRT807549	hsa-miR-3973	CLIP-seq
MIRT2177829	hsa-miR-4272	CLIP-seq
MIRT807552	hsa-miR-4277	CLIP-seq
MIRT807555	hsa-miR-4295	CLIP-seq
MIRT807560	hsa-miR-4436a	CLIP-seq
MIRT807562	hsa-miR-4477a	CLIP-seq
MIRT807563	hsa-miR-4482	CLIP-seq
MIRT807565	hsa-miR-4501	CLIP-seq
MIRT807569	hsa-miR-452	CLIP-seq
MIRT807571	hsa-miR-454	CLIP-seq
MIRT2177830	hsa-miR-4639-3p	CLIP-seq
MIRT807577	hsa-miR-4676-3p	CLIP-seq
MIRT807579	hsa-miR-4693-5p	CLIP-seq
MIRT807580	hsa-miR-4697-3p	CLIP-seq
MIRT807587	hsa-miR-4773	CLIP-seq
MIRT807590	hsa-miR-4799-5p	CLIP-seq
MIRT807592	hsa-miR-499-3p	CLIP-seq
MIRT807593	hsa-miR-499a-3p	CLIP-seq
MIRT807600	hsa-miR-519a	CLIP-seq
MIRT807601	hsa-miR-519b-3p	CLIP-seq
MIRT807602	hsa-miR-519c-3p	CLIP-seq
MIRT807603	hsa-miR-519d	CLIP-seq
MIRT807604	hsa-miR-520g	CLIP-seq
MIRT807605	hsa-miR-520h	CLIP-seq
MIRT2177831	hsa-miR-548aa	CLIP-seq
MIRT2177832	hsa-miR-548o	CLIP-seq
MIRT2177833	hsa-miR-562	CLIP-seq
MIRT807611	hsa-miR-573	CLIP-seq
MIRT807614	hsa-miR-579	CLIP-seq
MIRT807615	hsa-miR-582-5p	CLIP-seq
MIRT807617	hsa-miR-591	CLIP-seq
MIRT1938468	hsa-miR-640	CLIP-seq
MIRT807618	hsa-miR-641	CLIP-seq
MIRT2177834	hsa-miR-642a	CLIP-seq
MIRT807620	hsa-miR-653	CLIP-seq
MIRT807621	hsa-miR-655	CLIP-seq
MIRT1938469	hsa-miR-875-3p	CLIP-seq
MIRT1938470	hsa-miR-922	CLIP-seq
MIRT2177835	hsa-miR-92a	CLIP-seq
MIRT2177836	hsa-miR-92b	CLIP-seq
MIRT807623	hsa-miR-93	CLIP-seq
MIRT1938471	hsa-miR-935	CLIP-seq
MIRT807624	hsa-miR-944	CLIP-seq
MIRT2177837	hsa-miR-95	CLIP-seq
MIRT807500	hsa-miR-150	CLIP-seq
MIRT807569	hsa-miR-452	CLIP-seq
MIRT807577	hsa-miR-4676-3p	CLIP-seq
MIRT807579	hsa-miR-4693-5p	CLIP-seq
MIRT807614	hsa-miR-579	CLIP-seq
MIRT2177829	hsa-miR-4272	CLIP-seq
MIRT1938460	hsa-miR-431	CLIP-seq
MIRT807562	hsa-miR-4477a	CLIP-seq
MIRT2426555	hsa-miR-4685-5p	CLIP-seq
MIRT2426556	hsa-miR-511	CLIP-seq
MIRT1938470	hsa-miR-922	CLIP-seq
MIRT2177837	hsa-miR-95	CLIP-seq
MIRT807486	hsa-miR-1208	CLIP-seq
MIRT807488	hsa-miR-1225-5p	CLIP-seq
MIRT2481175	hsa-miR-2117	CLIP-seq
MIRT807524	hsa-miR-3194-3p	CLIP-seq
MIRT807525	hsa-miR-320a	CLIP-seq
MIRT807526	hsa-miR-320b	CLIP-seq
MIRT807527	hsa-miR-320c	CLIP-seq
MIRT807528	hsa-miR-320d	CLIP-seq
MIRT2481176	hsa-miR-3613-3p	CLIP-seq
MIRT807536	hsa-miR-3619-3p	CLIP-seq
MIRT807537	hsa-miR-3647-3p	CLIP-seq
MIRT1938458	hsa-miR-3682-3p	CLIP-seq
MIRT807545	hsa-miR-374c	CLIP-seq
MIRT807547	hsa-miR-3913-3p	CLIP-seq
MIRT2481177	hsa-miR-4426	CLIP-seq
MIRT807558	hsa-miR-4429	CLIP-seq
MIRT807560	hsa-miR-4436a	CLIP-seq
MIRT807566	hsa-miR-4502	CLIP-seq
MIRT2481178	hsa-miR-4647	CLIP-seq
MIRT2481179	hsa-miR-4662b	CLIP-seq
MIRT1938464	hsa-miR-4703-3p	CLIP-seq
MIRT2481180	hsa-miR-4753-3p	CLIP-seq
MIRT2481181	hsa-miR-489	CLIP-seq
MIRT807609	hsa-miR-548u	CLIP-seq
MIRT807613	hsa-miR-577	CLIP-seq
MIRT807617	hsa-miR-591	CLIP-seq
MIRT1938468	hsa-miR-640	CLIP-seq
MIRT2481182	hsa-miR-643	CLIP-seq
MIRT807621	hsa-miR-655	CLIP-seq
MIRT807486	hsa-miR-1208	CLIP-seq
MIRT807488	hsa-miR-1225-5p	CLIP-seq
MIRT2675649	hsa-miR-1253	CLIP-seq
MIRT2481175	hsa-miR-2117	CLIP-seq
MIRT2675650	hsa-miR-3185	CLIP-seq
MIRT807524	hsa-miR-3194-3p	CLIP-seq
MIRT807525	hsa-miR-320a	CLIP-seq
MIRT807526	hsa-miR-320b	CLIP-seq
MIRT807527	hsa-miR-320c	CLIP-seq
MIRT807528	hsa-miR-320d	CLIP-seq
MIRT2481176	hsa-miR-3613-3p	CLIP-seq
MIRT807536	hsa-miR-3619-3p	CLIP-seq
MIRT807537	hsa-miR-3647-3p	CLIP-seq
MIRT1938458	hsa-miR-3682-3p	CLIP-seq
MIRT807545	hsa-miR-374c	CLIP-seq
MIRT807547	hsa-miR-3913-3p	CLIP-seq
MIRT2675651	hsa-miR-3927	CLIP-seq
MIRT807549	hsa-miR-3973	CLIP-seq
MIRT2675652	hsa-miR-4311	CLIP-seq
MIRT2481177	hsa-miR-4426	CLIP-seq
MIRT807558	hsa-miR-4429	CLIP-seq
MIRT807560	hsa-miR-4436a	CLIP-seq
MIRT807566	hsa-miR-4502	CLIP-seq
MIRT2481178	hsa-miR-4647	CLIP-seq
MIRT2481179	hsa-miR-4662b	CLIP-seq
MIRT1938464	hsa-miR-4703-3p	CLIP-seq
MIRT2481180	hsa-miR-4753-3p	CLIP-seq
MIRT2481181	hsa-miR-489	CLIP-seq
MIRT807604	hsa-miR-520g	CLIP-seq
MIRT807605	hsa-miR-520h	CLIP-seq
MIRT807609	hsa-miR-548u	CLIP-seq
MIRT807613	hsa-miR-577	CLIP-seq
MIRT807617	hsa-miR-591	CLIP-seq
MIRT1938468	hsa-miR-640	CLIP-seq
MIRT2481182	hsa-miR-643	CLIP-seq
MIRT807621	hsa-miR-655	CLIP-seq

Show/Hide all (60)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0001772	Component	Immunological synapse	IEA
GO:0001772	Component	Immunological synapse	ISS
GO:0001818	Process	Negative regulation of cytokine production	IEA
GO:0001818	Process	Negative regulation of cytokine production	ISS
GO:0003056	Process	Regulation of vascular associated smooth muscle contraction	IEA
GO:0003056	Process	Regulation of vascular associated smooth muscle contraction	ISS
GO:0005388	Function	P-type calcium transporter activity	IBA
GO:0005388	Function	P-type calcium transporter activity	IEA
GO:0005388	Function	P-type calcium transporter activity	TAS	8396145
GO:0005515	Function	Protein binding	IPI	12763866, 18029012, 22084111, 30126976, 30190470
GO:0005516	Function	Calmodulin binding	IEA
GO:0005524	Function	ATP binding	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	18029012
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS	8396145
GO:0006811	Process	Monoatomic ion transport	IEA
GO:0006816	Process	Calcium ion transport	IEA
GO:0006874	Process	Intracellular calcium ion homeostasis	IEA
GO:0008217	Process	Regulation of blood pressure	IEA
GO:0008217	Process	Regulation of blood pressure	ISS
GO:0015085	Function	Calcium ion transmembrane transporter activity	IDA	18029012
GO:0015085	Function	Calcium ion transmembrane transporter activity	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IEA
GO:0016323	Component	Basolateral plasma membrane	IEA
GO:0016323	Component	Basolateral plasma membrane	ISS
GO:0016887	Function	ATP hydrolysis activity	IDA	30190470
GO:0016887	Function	ATP hydrolysis activity	IEA
GO:0030501	Process	Positive regulation of bone mineralization	IEA
GO:0030501	Process	Positive regulation of bone mineralization	ISS
GO:0030672	Component	Synaptic vesicle membrane	IEA
GO:0030672	Component	Synaptic vesicle membrane	ISS
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0034220	Process	Monoatomic ion transmembrane transport	TAS
GO:0042734	Component	Presynaptic membrane	IEA
GO:0042734	Component	Presynaptic membrane	ISS
GO:0042995	Component	Cell projection	IEA
GO:0043231	Component	Intracellular membrane-bounded organelle	IBA
GO:0045202	Component	Synapse	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0051480	Process	Regulation of cytosolic calcium ion concentration	IBA
GO:0051480	Process	Regulation of cytosolic calcium ion concentration	IDA	18029012
GO:0051480	Process	Regulation of cytosolic calcium ion concentration	IEA
GO:0051481	Process	Negative regulation of cytosolic calcium ion concentration	IEA
GO:0051481	Process	Negative regulation of cytosolic calcium ion concentration	IMP	29104511
GO:0051481	Process	Negative regulation of cytosolic calcium ion concentration	ISS
GO:0051928	Process	Positive regulation of calcium ion transport	IEA
GO:0051928	Process	Positive regulation of calcium ion transport	ISS
GO:0070062	Component	Extracellular exosome	HDA	20458337
GO:0070588	Process	Calcium ion transmembrane transport	IEA
GO:0098684	Component	Photoreceptor ribbon synapse	IEA
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0140678	Function	Molecular function inhibitor activity	IDA	30190470
GO:1900076	Process	Regulation of cellular response to insulin stimulus	IMP	29104511
GO:1903779	Process	Regulation of cardiac conduction	IEA
GO:1903779	Process	Regulation of cardiac conduction	TAS
GO:1990034	Process	Calcium ion export across plasma membrane	IDA	18029012

MIM	HGNC	e!Ensembl
108731	814	ENSG00000070961

P20020

Protein name

Plasma membrane calcium-transporting ATPase 1 (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 1) (PMCA1) (Plasma membrane calcium pump isoform 1)

Protein function

Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis (PubMed:35358416). Plays a role in blood pressure regulation through regula

PDB

6A69

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00690	Cation_ATPase_N	51 → 121	Cation transporter/ATPase, N-terminus	Domain
PF00122	E1-E2_ATPase	189 → 307		Family
PF00122	E1-E2_ATPase	347 → 453		Family
PF13246	Cation_ATPase	482 → 614		Family
PF00702	Hydrolase	658 → 809		Domain
PF00689	Cation_ATPase_C	879 → 1061	Cation transporting ATPase, C-terminus	Family
PF12424	ATP_Ca_trans_C	1103 → 1149	Plasma membrane calcium transporter ATPase C terminal	Family

Tissue specificity

TISSUE SPECIFICITY: Isoform B: Ubiquitously expressed. Isoform C: Found in brain cortex, skeletal muscle and heart muscle. Isoform D: Has only been found in fetal skeletal muscle. Isoform K: Found in small intestine and liver. Abundantly expressed in the

Sequence

MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGIC
TKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIV
SLGLSFYQPPEGDNALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQ
FRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDE
SSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEK
KDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKS
VLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFF
IIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTL
TMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGLPRH
VGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFS
KGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEP
EPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIAT
KCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGI
IDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVK
AVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASL
ALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGR
NAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVVQ
IIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEE
IPEEELAEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVNAFRSSLYEGLEKPESRSS
IHNFMTHPEFRIEDSEPHIPLIDDTDAEDDAPTKRNSSPPPSPNKNNNAVDSGIHLTIEM
NKSATSSSPGSPLHSLETSL

Sequence length

1220

Interactions

View interactions

	KEGG		Reactome
	Calcium signaling pathway cGMP-PKG signaling pathway cAMP signaling pathway Adrenergic signaling in cardiomyocytes Aldosterone synthesis and secretion Endocrine and other factor-regulated calcium reabsorption Salivary secretion Pancreatic secretion Mineral absorption		Reduction of cytosolic Ca++ levels Ion homeostasis Ion transport by P-type ATPases

Show/Hide Causal Diseases (9)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
ATP2B1-related disorder	Likely pathogenic	rs2540804470	RCV003397499
Clubfoot	Likely pathogenic	rs2135942244, rs370810713	RCV002266029 RCV002266030
Hypocalcemia	Likely pathogenic	rs2135942244, rs370810713	RCV002266029 RCV002266030
Intellectual developmental disorder, autosomal dominant 66	Likely pathogenic; Pathogenic	rs2136192267, rs2136158725, rs2136106360, rs1033577592, rs2136193860, rs2136050284, rs1883642606, rs2540804225, rs1879993052	RCV002260718 RCV002260719 RCV002260720 RCV002260721 RCV002260722 RCV002294523 RCV003387661 RCV003484444 RCV004762034
Intellectual disability, autosomal dominant 30	Likely pathogenic	rs1876205424	RCV003330165
Isolated Pierre-Robin syndrome	Likely pathogenic	rs2135942244, rs370810713	RCV002266029 RCV002266030
Neurodevelopmental delay	Likely pathogenic	rs2135942244, rs370810713	RCV002266029 RCV002266030
Neurodevelopmental disorder	Likely pathogenic; Pathogenic	rs2136192267, rs2136158725, rs2136106360, rs2135949570, rs1033577592, rs2136193860, rs1879711772, rs2540763693, rs1879993052	RCV002226602 RCV002226603 RCV002226604 RCV002226606 RCV002226608 RCV002226609 RCV002226610 RCV003389188 RCV001262498
Periventricular nodular heterotopia	Likely pathogenic	rs2135942244, rs370810713	RCV002266029 RCV002266030

Show/Hide Text Mining Associations (40)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Atherosclerosis	Associate	29902063
Autistic Disorder	Associate	35358416
Breast Neoplasms	Associate	35031021
Cardio Renal Syndrome	Associate	26534935
Cardiotoxicity	Associate	28851949
Cardiotoxicity	Inhibit	28851949
Cerebellar Ataxia	Associate	36207321
Cerebral Infarction	Associate	31173308
Colorectal Neoplasms	Associate	35194111, 37629096
Constriction Pathologic	Associate	29902063
Coronary Artery Disease	Associate	25740055, 26534935, 29902063
Coronary Disease	Associate	23727086
Developmental Disabilities	Associate	35358416
Diabetic Retinopathy	Inhibit	34935307
Dystonia	Associate	21868014
Eclampsia	Associate	31858526, 35253182
Edema	Associate	31858526
Esophageal Squamous Cell Carcinoma	Associate	37666951
Essential Hypertension	Associate	26933664, 31242870, 32555714
Hearing Loss	Associate	36207321
Heart Diseases	Associate	33760199
Hematologic Diseases	Associate	36718908
Hypersensitivity Delayed	Associate	35358416, 36207321
Hypertension	Associate	20921432, 23727086, 25385345, 26933664, 27149052, 28851949, 29902063, 29982197, 31242870, 31858526, 37175507, 39684400
Hypertension	Inhibit	33760199
Limb Deficiencies Distal with Micrognathia	Associate	35358416
Muscular Dystrophy Duchenne	Associate	36619896
Myalgia	Associate	21868014
Myocardial Infarction	Associate	23727086
Myocardial Ischemia	Associate	25385345
Necrosis	Inhibit	22733819
Neoplasms	Associate	28544176
Pre Eclampsia	Associate	24642721, 33760199
Pulmonary Arterial Hypertension	Associate	37176017
Renal Artery Obstruction	Associate	29902063
Seizures	Associate	35358416
Stiff Skin Syndrome	Associate	29902063
Stomach Neoplasms	Associate	36793271
Stroke	Associate	29902063
Vascular Diseases	Associate	34935307

ATP2B1 (ATPase plasma membrane Ca2+ transporting 1)