NQO2 (N-ribosyldihydronicotinamide:quinone dehydrogenase 2)
|
Gene
Gene information from NCBI Gene database.
|
|
| Entrez ID | 4835 |
| Gene name | N-ribosyldihydronicotinamide:quinone dehydrogenase 2 |
| Gene symbol | NQO2 |
| Synonyms (NCBI Gene) |
DHQVDIA6NMOR2QR2
|
| Chromosome | 6 |
| Chromosome location | 6p25.2 |
| Summary | This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutati |
|
miRNA
miRNA information provided by mirtarbase database.
249
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Transcription factors
Transcription factors information provided by TRRUST V2 database.
2
|
||||||||||
|
||||||||||
|
Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
22
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
|
|||||||
|
|||||||
|
Protein
Protein information from UniProt database.
|
|||||||||||
|
UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
|
P16083 | ||||||||||
| Protein name | Ribosyldihydronicotinamide dehydrogenase [quinone] (EC 1.10.5.1) (NRH dehydrogenase [quinone] 2) (NRH:quinone oxidoreductase 2) (Quinone reductase 2) (QR2) | ||||||||||
| Protein function | The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutama | ||||||||||
| PDB | 1QR2 , 1SG0 , 1XI2 , 1ZX1 , 2BZS , 2QMY , 2QMZ , 2QR2 , 2QWX , 2QX4 , 2QX6 , 2QX8 , 2QX9 , 3FW1 , 3G5M , 3GAM , 3NFR , 3NHF , 3NHJ , 3NHK , 3NHL , 3NHP , 3NHR , 3NHS , 3NHU , 3NHW , 3NHY , 3O2N , 3O73 , 3OVM , 3OWH , 3OWX , 3OX1 , 3OX2 , 3OX3 , 3TE7 , 3TEM , 3TZB , 3UXE , 3UXH , 4FGJ , 4FGK , 4FGL , 4GQI , 4GR9 , 4QOD , 4QOE , 4QOF , 4QOG , 4QOH , 4QOI | ||||||||||
| Family and domains |
Pfam
|
||||||||||
| Sequence |
|
||||||||||
| Sequence length | 231 | ||||||||||
| Interactions | View interactions | ||||||||||
|
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
|||||||
|
|||||||
|
Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
|
|||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||