NME1 (NME/NM23 nucleoside diphosphate kinase 1)

Gene

• Entrez ID: 4830
• Gene name: NME/NM23 nucleoside diphosphate kinase 1
• Gene symbol: NME1
• Synonyms (NCBI Gene): AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1
• Disease Acronyms (UniProt): NBS
• Chromosome: 17
• Chromosome location: 17q21.33
• Summary: This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of `A` (encoded by this gene) and `B` (encoded by NME2) isoforms. Mutations in this

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1187500	hsa-miR-1193	CLIP-seq
MIRT1187501	hsa-miR-1245b-3p	CLIP-seq
MIRT1187502	hsa-miR-1272	CLIP-seq
MIRT1187503	hsa-miR-1322	CLIP-seq
MIRT1187504	hsa-miR-141	CLIP-seq
MIRT1187505	hsa-miR-146a	CLIP-seq
MIRT1187506	hsa-miR-146b-5p	CLIP-seq
MIRT1187507	hsa-miR-1470	CLIP-seq
MIRT1187508	hsa-miR-1913	CLIP-seq
MIRT1187509	hsa-miR-200a	CLIP-seq
MIRT1187510	hsa-miR-28-3p	CLIP-seq
MIRT1187511	hsa-miR-3173-3p	CLIP-seq
MIRT1187512	hsa-miR-3192	CLIP-seq
MIRT1187513	hsa-miR-324-3p	CLIP-seq
MIRT1187514	hsa-miR-335	CLIP-seq
MIRT1187515	hsa-miR-346	CLIP-seq
MIRT1187516	hsa-miR-3607-3p	CLIP-seq
MIRT1187517	hsa-miR-3685	CLIP-seq
MIRT1187518	hsa-miR-3689a-3p	CLIP-seq
MIRT1187519	hsa-miR-3689c	CLIP-seq
MIRT1187520	hsa-miR-384	CLIP-seq
MIRT1187521	hsa-miR-3908	CLIP-seq
MIRT1187522	hsa-miR-3909	CLIP-seq
MIRT1187523	hsa-miR-4270	CLIP-seq
MIRT1187524	hsa-miR-4290	CLIP-seq
MIRT1187525	hsa-miR-4441	CLIP-seq
MIRT1187526	hsa-miR-4527	CLIP-seq
MIRT1187527	hsa-miR-4533	CLIP-seq
MIRT1187528	hsa-miR-4641	CLIP-seq
MIRT1187529	hsa-miR-4667-3p	CLIP-seq
MIRT1187530	hsa-miR-4670-3p	CLIP-seq
MIRT1187531	hsa-miR-4694-3p	CLIP-seq
MIRT1187532	hsa-miR-4728-3p	CLIP-seq
MIRT1187533	hsa-miR-4728-5p	CLIP-seq
MIRT1187534	hsa-miR-4731-5p	CLIP-seq
MIRT1187535	hsa-miR-4747-5p	CLIP-seq
MIRT1187536	hsa-miR-4764-5p	CLIP-seq
MIRT1187537	hsa-miR-4779	CLIP-seq
MIRT1187538	hsa-miR-486-5p	CLIP-seq
MIRT1187539	hsa-miR-542-5p	CLIP-seq
MIRT1187540	hsa-miR-642a	CLIP-seq
MIRT1187502	hsa-miR-1272	CLIP-seq
MIRT1187503	hsa-miR-1322	CLIP-seq
MIRT1187504	hsa-miR-141	CLIP-seq
MIRT1187505	hsa-miR-146a	CLIP-seq
MIRT1187506	hsa-miR-146b-5p	CLIP-seq
MIRT1187507	hsa-miR-1470	CLIP-seq
MIRT1187508	hsa-miR-1913	CLIP-seq
MIRT1187509	hsa-miR-200a	CLIP-seq
MIRT1187510	hsa-miR-28-3p	CLIP-seq
MIRT1187511	hsa-miR-3173-3p	CLIP-seq
MIRT1187512	hsa-miR-3192	CLIP-seq
MIRT1187513	hsa-miR-324-3p	CLIP-seq
MIRT1187514	hsa-miR-335	CLIP-seq
MIRT1187517	hsa-miR-3685	CLIP-seq
MIRT1187518	hsa-miR-3689a-3p	CLIP-seq
MIRT1187519	hsa-miR-3689c	CLIP-seq
MIRT1187520	hsa-miR-384	CLIP-seq
MIRT1187522	hsa-miR-3909	CLIP-seq
MIRT1187523	hsa-miR-4270	CLIP-seq
MIRT1187525	hsa-miR-4441	CLIP-seq
MIRT1187527	hsa-miR-4533	CLIP-seq
MIRT1187528	hsa-miR-4641	CLIP-seq
MIRT1187529	hsa-miR-4667-3p	CLIP-seq
MIRT1187530	hsa-miR-4670-3p	CLIP-seq
MIRT1187532	hsa-miR-4728-3p	CLIP-seq
MIRT1187533	hsa-miR-4728-5p	CLIP-seq
MIRT1187534	hsa-miR-4731-5p	CLIP-seq
MIRT1187535	hsa-miR-4747-5p	CLIP-seq
MIRT1187537	hsa-miR-4779	CLIP-seq
MIRT1187540	hsa-miR-642a	CLIP-seq
MIRT1187500	hsa-miR-1193	CLIP-seq
MIRT1187501	hsa-miR-1245b-3p	CLIP-seq
MIRT1187502	hsa-miR-1272	CLIP-seq
MIRT1187503	hsa-miR-1322	CLIP-seq
MIRT1187504	hsa-miR-141	CLIP-seq
MIRT1187505	hsa-miR-146a	CLIP-seq
MIRT1187506	hsa-miR-146b-5p	CLIP-seq
MIRT1187507	hsa-miR-1470	CLIP-seq
MIRT1187509	hsa-miR-200a	CLIP-seq
MIRT1187510	hsa-miR-28-3p	CLIP-seq
MIRT1187512	hsa-miR-3192	CLIP-seq
MIRT1187514	hsa-miR-335	CLIP-seq
MIRT1187516	hsa-miR-3607-3p	CLIP-seq
MIRT1187518	hsa-miR-3689a-3p	CLIP-seq
MIRT1187519	hsa-miR-3689c	CLIP-seq
MIRT1187523	hsa-miR-4270	CLIP-seq
MIRT1187525	hsa-miR-4441	CLIP-seq
MIRT1187529	hsa-miR-4667-3p	CLIP-seq
MIRT1187530	hsa-miR-4670-3p	CLIP-seq
MIRT1187532	hsa-miR-4728-3p	CLIP-seq
MIRT1187533	hsa-miR-4728-5p	CLIP-seq
MIRT1187534	hsa-miR-4731-5p	CLIP-seq
MIRT1187538	hsa-miR-486-5p	CLIP-seq
MIRT1187539	hsa-miR-542-5p	CLIP-seq
MIRT1187540	hsa-miR-642a	CLIP-seq
MIRT1187500	hsa-miR-1193	CLIP-seq
MIRT1187504	hsa-miR-141	CLIP-seq
MIRT1187509	hsa-miR-200a	CLIP-seq
MIRT1187539	hsa-miR-542-5p	CLIP-seq
MIRT1187507	hsa-miR-1470	CLIP-seq
MIRT1187514	hsa-miR-335	CLIP-seq
MIRT1187529	hsa-miR-4667-3p	CLIP-seq
MIRT1187540	hsa-miR-642a	CLIP-seq
MIRT1187502	hsa-miR-1272	CLIP-seq
MIRT1187503	hsa-miR-1322	CLIP-seq
MIRT1187507	hsa-miR-1470	CLIP-seq
MIRT1187510	hsa-miR-28-3p	CLIP-seq
MIRT1187514	hsa-miR-335	CLIP-seq
MIRT1187516	hsa-miR-3607-3p	CLIP-seq
MIRT1187517	hsa-miR-3685	CLIP-seq
MIRT1187520	hsa-miR-384	CLIP-seq
MIRT1187529	hsa-miR-4667-3p	CLIP-seq
MIRT1187530	hsa-miR-4670-3p	CLIP-seq
MIRT1187538	hsa-miR-486-5p	CLIP-seq
MIRT1187540	hsa-miR-642a	CLIP-seq
MIRT1187502	hsa-miR-1272	CLIP-seq
MIRT1187503	hsa-miR-1322	CLIP-seq
MIRT1187507	hsa-miR-1470	CLIP-seq
MIRT1187514	hsa-miR-335	CLIP-seq
MIRT1187529	hsa-miR-4667-3p	CLIP-seq
MIRT1187530	hsa-miR-4670-3p	CLIP-seq
MIRT1187538	hsa-miR-486-5p	CLIP-seq
MIRT1187540	hsa-miR-642a	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
STAT3	Activation	23583378
TP53	Unknown	12669312

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000287	Function	Magnesium ion binding	IDA	11555662
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IEA
GO:0002762	Process	Negative regulation of myeloid leukocyte differentiation	IEA
GO:0003697	Function	Single-stranded DNA binding	IEA
GO:0003723	Function	RNA binding	HDA	22658674
GO:0004536	Function	Deoxyribonuclease activity	IDA	11555662
GO:0004550	Function	Nucleoside diphosphate kinase activity	IBA	21873635
GO:0004550	Function	Nucleoside diphosphate kinase activity	IDA	12972261
GO:0005515	Function	Protein binding	IPI	10602478, 11701125, 15684389, 16189514, 17314099, 17975005, 18470881, 19060904, 21988832, 25416956, 27499296, 31515488, 31980649, 32296183
GO:0005524	Function	ATP binding	IDA	12972261
GO:0005525	Function	GTP binding	IDA	12972261
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005634	Component	Nucleus	IDA	16814409
GO:0005634	Component	Nucleus	TAS	16130169
GO:0005737	Component	Cytoplasm	TAS	16130169
GO:0005741	Component	Mitochondrial outer membrane	IEA
GO:0005813	Component	Centrosome	IEA
GO:0005829	Component	Cytosol	IDA	16814409
GO:0005829	Component	Cytosol	TAS
GO:0005882	Component	Intermediate filament	IEA
GO:0006165	Process	Nucleoside diphosphate phosphorylation	IEA
GO:0006183	Process	GTP biosynthetic process	IEA
GO:0006228	Process	UTP biosynthetic process	IEA
GO:0006241	Process	CTP biosynthetic process	IEA
GO:0006259	Process	DNA metabolic process	IEA
GO:0006897	Process	Endocytosis	IEA
GO:0007595	Process	Lactation	IEA
GO:0008285	Process	Negative regulation of cell population proliferation	TAS	1851158
GO:0010629	Process	Negative regulation of gene expression	IEA
GO:0010976	Process	Positive regulation of neuron projection development	IEA
GO:0014075	Process	Response to amine	IEA
GO:0015949	Process	Nucleobase-containing small molecule interconversion	TAS
GO:0016020	Component	Membrane	HDA	19946888
GO:0019215	Function	Intermediate filament binding	IEA
GO:0019899	Function	Enzyme binding	IEA
GO:0021766	Process	Hippocampus development	IEA
GO:0030154	Process	Cell differentiation	IEA
GO:0032587	Component	Ruffle membrane	IDA	16814409
GO:0033574	Process	Response to testosterone	IEA
GO:0035690	Process	Cellular response to drug	IEA
GO:0042802	Function	Identical protein binding	IPI	10602478, 16189514, 17314099, 25416956, 25502805, 25910212, 31515488, 32296183
GO:0042981	Process	Regulation of apoptotic process	TAS	16130169
GO:0043015	Function	Gamma-tubulin binding	IEA
GO:0043024	Function	Ribosomal small subunit binding	IPI	16814409
GO:0043388	Process	Positive regulation of DNA binding	IDA	17975005
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0050679	Process	Positive regulation of epithelial cell proliferation	IMP	16862176
GO:0051591	Process	Response to cAMP	IEA
GO:0070062	Component	Extracellular exosome	HDA	23533145
GO:0071333	Process	Cellular response to glucose stimulus	IEA
GO:0071398	Process	Cellular response to fatty acid	IEA

Other IDs

• MIM: 156490
• HGNC: 7849
• e!Ensembl: ENSG00000239672

Protein

• UniProt ID: P15531
• Protein name: Nucleoside diphosphate kinase A (NDK A) (NDP kinase A) (EC 2.7.4.6) (Granzyme A-activated DNase) (GAAD) (Metastasis inhibition factor nm23) (NM23-H1) (Tumor metastatic process-associated protein)
• Protein function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate
• PDB: 1JXV, 1UCN, 2HVD, 2HVE, 3L7U, 4ENO, 5UI4, 8OOV
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00334	NDK	5 → 139	Nucleoside diphosphate kinase	Domain

• Tissue specificity: TISSUE SPECIFICITY: Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression
• Sequence:

  MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPF
  FAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS
  DSVESAEKEIGLWFHPEELVDYTSCAQNWIYE

• Sequence length: 152

Pathways

KEGG:

Purine metabolism
Pyrimidine metabolism
Drug metabolism - other enzymes
Metabolic pathways
Nucleotide metabolism
Biosynthesis of cofactors

Reactome:

Interconversion of nucleotide di- and triphosphates

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Colorectal cancer	Colorectal Carcinoma	rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800, rs63750198, rs63751109, rs863223312, rs63750710, rs63751615, rs63750206, rs63750781, rs63750899, rs63750691, rs63750217, rs121912965, rs63749939, rs63751194, rs63750693, rs63750540, rs63751221, rs193922370, rs80359596, rs397514632, rs483352909, rs200495564, rs397514684, rs397516436, rs398122386, rs79512956, rs74953290, rs587779001, rs63750677, rs63749837, rs267607816, rs63751715, rs267607819, rs267607815, rs267607822, rs63749906, rs587778883, rs63750472, rs63751012, rs63750715, rs63750580, rs267607706, rs267607709, rs267607710, rs587778894, rs63750749, rs63750483, rs63751015, rs63751153, rs63751094, rs63751118, rs63750316, rs63749981, rs587778906, rs267607821, rs587778908, rs63750020, rs587778909, rs63750713, rs267607825, rs63751592, rs281864936, rs587778913, rs587778914, rs63749795, rs63750855, rs63749916, rs63749923, rs63751472, rs63751689, rs267607832, rs267607837, rs267607836, rs587778923, rs63750028, rs587778928, rs587778929, rs587778930, rs63751277, rs587778933, rs267607842, rs267607843, rs63750192, rs587778934, rs63750193, rs587778937, rs587778938, rs267607845, rs63751244, rs63751393, rs63751460, rs267607849, rs267607853, rs267607856, rs267607850, rs63751657, rs267607854, rs267607852, rs587778942, rs63750309, rs63750587, rs63749863, rs63751486, rs63750016, rs63749868, rs63750375, rs63750035, rs63750604, rs63750386, rs63750150, rs63750486, rs63751428, rs267607866, rs63749986, rs63751594, rs63750152, rs63750850, rs267607867, rs267607868, rs63751632, rs267607871, rs63751892, rs587778956, rs63750469, rs587778958, rs63749792, rs267607875, rs63751255, rs281864938, rs63751202, rs63750726, rs63751310, rs63749900, rs587778964, rs267607879, rs267607878, rs587778966, rs267607883, rs267607887, rs63750061, rs63750663, rs587778968, rs587778971, rs63750809, rs63749867, rs63750864, rs587778972, rs63751275, rs267607718, rs267607722, rs63750769, rs267607717, rs587778973, rs267607716, rs267607720, rs63749995, rs63750859, rs587778975, rs63750114, rs587778976, rs63750603, rs267607889, rs267607723, rs63750561, rs63750499, rs63751642, rs63751022, rs587778981, rs63750971, rs267607898, rs267607906, rs267607903, rs587778989, rs587778992, rs267607894, rs267607901, rs267607892, rs63750437, rs587778997, rs587778998, rs63750005, rs63750641, rs63751421, rs11541859, rs63750266, rs111052004, rs267607726, rs267607727, rs63750453, rs267607734, rs267607735, rs63751665, rs267607736, rs267607732, rs63749816, rs63750539, rs267607739, rs587779006, rs587779008, rs267607745, rs267607742, rs63751595, rs267607743, rs587779010, rs587779012, rs63750057, rs63749818, rs63751124, rs587779014, rs587779015, rs63749820, rs63751302, rs267607750, rs267607751, rs267607749, rs63750891, rs63749959, rs63749804, rs267607765, rs267607760, rs587779021, rs267607759, rs63750515, rs587779023, rs63751021, rs63751480, rs267607772, rs267607773, rs587779024, rs63751653, rs587779027, rs267607767, rs587779029, rs63750706, rs63750385, rs267607774, rs267607778, rs267607780, rs587779034, rs63751711, rs267607784, rs587779035, rs63750823, rs63750822, rs267607787, rs63750303, rs63749839, rs63749827, rs267607789, rs267607790, rs267607791, rs267607786, rs267607771, rs267607795, rs267607794, rs267607788, rs267607799, rs267607801, rs587779045, rs63750034, rs587779047, rs63750216, rs63751707, rs63751598, rs267607803, rs267607777, rs63750144, rs267607805, rs63750547, rs63750489, rs63750993, rs587779054, rs63751259, rs63749926, rs63750796, rs587779058, rs63750745, rs63750582, rs180177084, rs587779866, rs200389141, rs587779950, rs587780104, rs587780183, rs587778536, rs587780683, rs587781554, rs267607712, rs587777627, rs587783057, rs730881734, rs41542214, rs730881273, rs786203456, rs786201990, rs786202767, rs748005072, rs786204317, rs786204318, rs797045117, rs63750549, rs863225383, rs863225384, rs863225373, rs863225376, rs863225377, rs863225378, rs863225379, rs863225380, rs863225381, rs63750059, rs267607823, rs864622457, rs869312767, rs869312753, rs876661059, rs876658915, rs876658923, rs876660860, rs876660822, rs876660458, rs876660214, rs876658657, rs876658247, rs876659226, rs876658821, rs876660589, rs876659068, rs876659681, rs876659608, rs878853794, rs878853778, rs878853780, rs878853785, rs886039423, rs886039424, rs1057517543, rs1057517541, rs756843954, rs1057517617, rs1057517558, rs1057519256, rs1060500689, rs764085979, rs1060500707, rs1060500699, rs1060500706, rs1060500703, rs1064795341, rs1064793607, rs1064794348, rs1064795441, rs1064794373, rs1064793172, rs1064794122, rs1064795515, rs1064794331, rs63750978, rs1114167435, rs1553641362, rs63751448, rs1553648029, rs1553648058, rs587778903, rs1553653237, rs1553664353, rs267607744, rs1553647995, rs1553648047, rs1553653084, rs1553663750, rs1553664436, rs1553488015, rs1553637293, rs63750310, rs63750443, rs63751596, rs1553646681, rs550890395, rs1064796057, rs1553642079, rs1553648023, rs587782087, rs746536721, rs1553653037, rs1248251121, rs1553646602, rs1434898623, rs1553665683, rs1553648068, rs1553645331, rs1553644123, rs1553658246, rs1553651299, rs1553648149, rs1553663159, rs1302248679, rs1553664119, rs1553658009, rs1553665977, rs1416171624, rs1553663834, rs1553664617, rs1553664702, rs1553647969, rs1553648040, rs1437454428, rs1553641273, rs63751101, rs1553646764, rs1553648225, rs1554082118, rs1553648201, rs1553638868, rs1553665866, rs376736188, rs1553642707, rs1553645226, rs1553652883, rs63751435, rs1553653115, rs1553653195, rs63750300, rs1553662622, rs1553658104, rs1553648220, rs1559544064, rs63750584, rs267608083, rs1559551570, rs1559575107, rs1559553501, rs1565986506, rs1559524405, rs1559553492, rs1559554339, rs1559588540, rs1559558071, rs761329565, rs1559521039, rs1559574795, rs1567221417, rs1559578422, rs1481129490, rs1570714352, rs779783209, rs1575376830, rs1575469070, rs1575537843, rs1575620443, rs1575621506, rs587779022, rs1575414904, rs1575449093, rs1575469505, rs1575536254, rs1575537933, rs1575632112, rs1575639851, rs1575441094, rs1575449402, rs267607831, rs2081922847, rs2083403132, rs2085415927, rs2085469647, rs2043913790, rs147542208	15814641
Colorectal neoplasms	Colorectal Neoplasms	rs28929483, rs63751108, rs28929484, rs63749831, rs63750047, rs63751207, rs63749811, rs1553350126, rs63750875, rs63750955, rs587776706, rs63750871, rs587776715, rs63751466, rs63750049, rs63750451, rs121434629, rs63751247, rs63750710, rs63751615, rs63750781, rs63750899, rs63750691, rs63749939, rs63751194, rs63750693, rs63750540, rs63751221, rs193922370, rs63750245, rs193922372, rs63750393, rs63749932, rs193922375, rs193922376, rs193922343, rs397514684, rs397515875, rs267608094, rs587779204, rs267608077, rs587779206, rs63750439, rs63751405, rs63750741, rs63750854, rs63750909, rs587779212, rs587779215, rs587779216, rs587779219, rs63749874, rs267608076, rs587779220, rs267608050, rs63750735, rs63750564, rs71539659, rs267608082, rs63751167, rs267608057, rs587779227, rs267608068, rs63750075, rs587779228, rs63751419, rs587779231, rs587779232, rs267608058, rs63751442, rs63751127, rs63750647, rs63750138, rs587779235, rs267608065, rs63751321, rs587779241, rs587779243, rs63750904, rs63751017, rs587779246, rs267608063, rs63750140, rs63750940, rs63750111, rs587779250, rs63750258, rs63750563, rs267608073, rs63751407, rs267608059, rs63749999, rs267608042, rs63750833, rs587779255, rs587779256, rs63749821, rs63749843, rs63750617, rs267608078, rs587779259, rs267608092, rs587779260, rs267608086, rs1553331676, rs63750356, rs587779263, rs267608098, rs587779264, rs587779267, rs63750194, rs63751327, rs587779269, rs63751328, rs587779274, rs587779279, rs267608111, rs1553332996, rs587779284, rs63749942, rs587779288, rs63751058, rs63750554, rs267608114, rs267608118, rs63750139, rs63751319, rs267608128, rs587779295, rs267608127, rs267608126, rs63750767, rs267608120, rs587779299, rs267608121, rs587779301, rs267608131, rs267608122, rs63749873, rs63751077, rs1800937, rs587779315, rs587779318, rs63750019, rs267608066, rs63749980, rs63750552, rs1553412283, rs146816935, rs587779001, rs63750677, rs63750339, rs63751609, rs267607816, rs63751715, rs267607819, rs267607815, rs267607822, rs587778882, rs587778883, rs63751012, rs63750715, rs63750580, rs587778888, rs267607706, rs267607709, rs267607710, rs587778894, rs63750749, rs63750483, rs587778896, rs63751015, rs267607713, rs63751153, rs63751094, rs63751118, rs63750316, rs63749981, rs587778906, rs267607821, rs587778908, rs63750020, rs63750713, rs267607825, rs63751592, rs281864936, rs587778913, rs587778914, rs63749795, rs63750855, rs63749916, rs63749923, rs63751472, rs63751689, rs267607837, rs267607836, rs63750028, rs587778930, rs63751277, rs587778933, rs267607843, rs63750192, rs63750300, rs63750193, rs587778938, rs267607845, rs63751244, rs63751393, rs63751460, rs267607849, rs63751608, rs267607853, rs267607856, rs267607850, rs63751657, rs267607854, rs267607852, rs587778942, rs63750587, rs63749863, rs63749868, rs63750035, rs63750604, rs63750150, rs63750486, rs63751428, rs267607866, rs63749986, rs63750152, rs63750850, rs267607867, rs267607869, rs63751632, rs267607871, rs587778956, rs63749792, rs267607875, rs63750610, rs281864938, rs63751465, rs63751202, rs63750726, rs63751310, rs63749900, rs587778964, rs267607879, rs267607878, rs63751662, rs267607884, rs267607883, rs63750639, rs63750206, rs587778967, rs63750663, rs587778971, rs63750809, rs63749867, rs63750864, rs587778972, rs63751275, rs267607718, rs267607722, rs267607717, rs587778973, rs267607720, rs63749995, rs63750859, rs587778975, rs63750114, rs267607888, rs587778976, rs63750603, rs267607889, rs267607723, rs63750561, rs63751642, rs63751022, rs587778983, rs587778984, rs267607898, rs267607906, rs267607903, rs587778989, rs587778992, rs267607894, rs267607901, rs267607892, rs63749859, rs63750437, rs587778997, rs63749990, rs587778998, rs63750005, rs63750641, rs63751421, rs63750266, rs111052004, rs267607726, rs63750453, rs267607734, rs267607735, rs63751665, rs267607732, rs63749816, rs63750539, rs587779006, rs63751606, rs587779008, rs267607745, rs267607742, rs63751595, rs267607743, rs63750866, rs63750865, rs587779010, rs587779012, rs63750057, rs72481822, rs587779014, rs587779015, rs63751045, rs63749820, rs267607750, rs267607749, rs267607753, rs63750891, rs63749959, rs63749804, rs63750903, rs63750211, rs267607765, rs267607760, rs587779021, rs587779022, rs267607759, rs63750515, rs63750648, rs63751480, rs267607772, rs587779024, rs267607768, rs63751653, rs587779027, rs267607767, rs63750581, rs63750706, rs63750385, rs587779031, rs267607774, rs267607778, rs267607780, rs587779034, rs63751711, rs267607784, rs587779035, rs267607785, rs267607783, rs63750823, rs63750822, rs267607787, rs63750303, rs587779037, rs63750948, rs63749827, rs587779039, rs267607789, rs267607790, rs267607791, rs267607786, rs267607795, rs267607794, rs267607788, rs63750792, rs63749950, rs587779045, rs63750034, rs587779047, rs63750216, rs63750517, rs63751707, rs63751598, rs267607803, rs267607777, rs63750144, rs267607805, rs63750547, rs63750489, rs587779054, rs587779055, rs63751259, rs63749926, rs63750796, rs587779058, rs63751197, rs587779063, rs63750778, rs63751004, rs63751147, rs63751027, rs63750396, rs587779067, rs267607940, rs267607943, rs63751617, rs63750558, rs63750267, rs63749849, rs587779075, rs63750302, rs63750611, rs63750984, rs63750586, rs63751412, rs63751413, rs587779076, rs63751142, rs63750086, rs63750006, rs267607950, rs267607949, rs63751693, rs587779083, rs587779084, rs63750807, rs63749920, rs267607954, rs267607957, rs587779087, rs63750384, rs63750615, rs63750068, rs63749947, rs1114167806, rs63750936, rs267607962, rs587779097, rs63750780, rs63749930, rs63750224, rs63750094, rs63750337, rs63751656, rs267607969, rs267607972, rs63750597, rs267607970, rs267607971, rs587779101, rs587779103, rs63751149, rs63750474, rs587779105, rs63751411, rs587779108, rs267607976, rs63751140, rs587779110, rs267607977, rs63750200, rs63751236, rs267607985, rs63750951, rs587779112, rs63750493, rs267607984, rs63750312, rs63750508, rs63750280, rs63750160, rs63750203, rs63750960, rs63750893, rs63751317, rs587779119, rs267607986, rs267607987, rs587779125, rs267607988, rs267607990, rs63751640, rs63751123, rs587779129, rs587779131, rs267607995, rs63750199, rs587779133, rs63749993, rs63750232, rs63751432, rs267607994, rs63750961, rs63750398, rs587779136, rs267607915, rs267607914, rs267607917, rs587779138, rs63750636, rs63751453, rs587779139, rs63750572, rs267608002, rs267608006, rs267607979, rs267608001, rs63751155, rs63751477, rs63750042, rs63749854, rs587779143, rs63751105, rs63750346, rs63749848, rs63750618, rs63750149, rs63750233, rs63750803, rs63750463, rs63749983, rs63751018, rs63749917, rs267608010, rs267608012, rs63751621, rs63750623, rs63751117, rs63751447, rs587779148, rs63750857, rs587779149, rs63749830, rs63750849, rs63750291, rs63751618, rs267608019, rs267608017, rs63751624, rs267608020, rs587779153, rs63751469, rs267607920, rs63750084, rs63750808, rs63751007, rs63751429, rs63750970, rs63751099, rs63750318, rs587779157, rs63750501, rs63750614, rs587779159, rs63750458, rs267607924, rs267607925, rs63750924, rs63750704, rs63750408, rs63750910, rs63751426, rs63750624, rs63750214, rs63750582, rs587779163, rs63750843, rs63750933, rs63750070, rs587779164, rs63750382, rs63750551, rs63751444, rs63750088, rs587779165, rs63751326, rs63750682, rs63751110, rs63751136, rs587779167, rs63750574, rs63749984, rs63751622, rs63751274, rs267607689, rs587779169, rs267607930, rs267607929, rs63751602, rs587779170, rs63749897, rs63750426, rs281864944, rs63750488, rs63749832, rs63750347, rs267607934, rs587779185, rs63750091, rs63750276, rs63750097, rs587779189, rs587779190, rs587779191, rs63750934, rs63750885, rs63749915, rs63749914, rs63750640, rs587779193, rs587779195, rs12476364, rs587779198, rs63750502, rs63751044, rs63750630, rs63750468, rs63750828, rs267608156, rs587779326, rs587778617, rs587779330, rs267608169, rs63750477, rs63750793, rs63750250, rs63750490, rs63751422, rs201451115, rs587779333, rs267608170, rs267608161, rs267608172, rs63750695, rs587779336, rs267608173, rs267608160, rs1554306445, rs587779338, rs63751029, rs267608148, rs587779343, rs63750261, rs267608147, rs587779344, rs267608149, rs267608151, rs267608154, rs63750246, rs267608153, rs200640585, rs143277125, rs587779347, rs398123231, rs398123232, rs587779778, rs587779254, rs587779914, rs200492211, rs587779936, rs587779941, rs587779950, rs587779964, rs587779979, rs587780059, rs188006077, rs587780062, rs587780064, rs587780538, rs587778618, rs587780683, rs587780724, rs63751427, rs587781317, rs63750119, rs587781339, rs587781372, rs587781395, rs267608064, rs587781462, rs63750737, rs587781544, rs587781554, rs587781626, rs587781691, rs587781716, rs587782074, rs587782111, rs587782277, rs587782326, rs587782336, rs587782561, rs587782593, rs141577476, rs587782659, rs587782704, rs63751604, rs587782710, rs587782712, rs267607712, rs587782787, rs587783056, rs373885654, rs730881775, rs587779166, rs730881774, rs730881816, rs730881825, rs730881827, rs730881829, rs730881830, rs730881734, rs41542214, rs786202037, rs786203424, rs786203604, rs786201066, rs786203036, rs786201590, rs786203704, rs786201042, rs786203597, rs587782281, rs786202848, rs786201049, rs750528093, rs786202363, rs786202108, rs267608083, rs786201050, rs374230313, rs786203924, rs786202842, rs786203331, rs786201084, rs1553333738, rs267607716, rs786202328, rs786203456, rs786201990, rs786201039, rs786201062, rs778531080, rs786203073, rs63751228, rs786201047, rs573125799, rs786203954, rs786202098, rs587779340, rs763308607, rs786204082, rs786204144, rs786204050, rs786204252, rs786204104, rs786204321, rs869320619, rs863224481, rs863224833, rs863224473, rs863224829, rs863224474, rs863224475, rs863224476, rs863224480, rs63750549, rs863224498, rs863224497, rs863224496, rs267608159, rs863224450, rs863224676, rs863225397, rs863225386, rs863225387, rs267607953, rs863225389, rs863225390, rs370970617, rs759263820, rs863225392, rs863225394, rs863225395, rs863225402, rs863225421, rs863225398, rs863225399, rs863225400, rs863225403, rs863225404, rs863225406, rs587782562, rs863225408, rs863225409, rs863225412, rs863225416, rs863225418, rs863225383, rs863225384, rs863225377, rs863225378, rs863225381, rs864622041, rs63750059, rs1553350680, rs864622183, rs63749991, rs864622340, rs63750330, rs864622436, rs864622121, rs864622435, rs864622153, rs864622257, rs864622585, rs864622607, rs786203968, rs267607744, rs267607823, rs267607832, rs864622457, rs864622600, rs3209663, rs869312768, rs869312769, rs869312770, rs869312767, rs759151952, rs876657701, rs876661033, rs876661205, rs876661025, rs876661193, rs63749919, rs876661073, rs876661222, rs876661171, rs876661159, rs63749818, rs876658915, rs876661113, rs876661203, rs766389591, rs760228510, rs763939668, rs876660480, rs876658996, rs876660655, rs876658918, rs876658223, rs876660711, rs876658211, rs876660095, rs876658296, rs876660549, rs876658881, rs876660630, rs876659189, rs876660283, rs876660943, rs866771359, rs876658817, rs876658962, rs876658339, rs876658657, rs876658821, rs876659068, rs63750217, rs876659681, rs876659608, rs876659480, rs876659900, rs876660459, rs876658862, rs587782898, rs876658964, rs876659736, rs878853815, rs878853824, rs878853802, rs878853809, rs267608041, rs878853702, rs878853709, rs878853711, rs878853718, rs878853721, rs878853729, rs878853736, rs878853739, rs878853742, rs878853745, rs878853792, rs878853794, rs878853777, rs878853778, rs878853780, rs878853785, rs878853787, rs878854037, rs878854060, rs878854059, rs763872353, rs879254025, rs879254104, rs879253899, rs879254234, rs1553640314, rs886039424, rs886039646, rs886039615, rs886044911, rs63750058, rs1057517551, rs1057517541, rs756843954, rs1057517764, rs1057517763, rs1057517801, rs769742496, rs1057520605, rs1057520735, rs1057524433, rs786202083, rs1553350787, rs1060502035, rs267607694, rs1060502039, rs1060502014, rs1060502038, rs1060502032, rs1060502001, rs1060502000, rs1060502885, rs1060502941, rs1060502029, rs775464903, rs1064792951, rs1553413673, rs1060502918, rs1060502876, rs1060502888, rs1060502932, rs1060502901, rs1060502891, rs1060502940, rs1060502937, rs1060502926, rs1060502886, rs1060501993, rs1060501989, rs1060502890, rs1060502027, rs1060502023, rs1060501991, rs1060502903, rs1553333432, rs1060502875, rs1060502946, rs1060502882, rs1060502881, rs1060500689, rs764085979, rs1060500707, rs1064792918, rs1060500698, rs1060500699, rs1060500706, rs63750867, rs1060500688, rs1060500703, rs1060500692, rs1060500687, rs1060503142, rs111466480, rs1060503137, rs746766787, rs758304323, rs764342199, rs876659162, rs1554300763, rs730881920, rs1060503148, rs1060503110, rs1060503138, rs1064794155, rs1064794809, rs1553352505, rs267607939, rs876658187, rs1064793561, rs1064795653, rs1064795329, rs267608011, rs1064794075, rs1553411392, rs1023534466, rs1553412609, rs1064794388, rs1064793600, rs1064795256, rs1064795591, rs1064794055, rs1064794164, rs1553414010, rs1064793671, rs1064794943, rs876660853, rs1064793489, rs1064795629, rs1064794384, rs1553333072, rs1553333078, rs1553333127, rs1553333500, rs1064793895, rs760190301, rs1064795341, rs1064793607, rs587778968, rs1064795441, rs1064794612, rs1064795515, rs1064794267, rs1064793823, rs1064794331, rs63750978, rs1064796500, rs1064794566, rs1064793234, rs757324104, rs1064794905, rs1064795447, rs1064796190, rs1064793868, rs1554304940, rs1064794083, rs1064795705, rs1064794173, rs1064794152, rs1085308057, rs1114167435, rs1114167883, rs1114167831, rs1114167877, rs1114167855, rs587782537, rs1114167814, rs1114167848, rs1114167845, rs979212552, rs1114167809, rs1114167858, rs1553356720, rs1114167833, rs1114167852, rs1114167835, rs1114167854, rs1114167815, rs267607982, rs1114167844, rs1114167805, rs730881762, rs1114167857, rs1114167832, rs1114167826, rs1114167841, rs1114167828, rs1114167818, rs1114167719, rs1114167776, rs1114167689, rs1114167728, rs1114167692, rs1114167725, rs1114167704, rs1114167696, rs1114167748, rs1114167763, rs1114167804, rs1114167731, rs1114167801, rs753796271, rs1114167736, rs1114167756, rs267608055, rs1114167746, rs1114167715, rs587782706, rs1114167750, rs1114167702, rs1114167765, rs587780670, rs1114167766, rs777159874, rs587782638, rs1114167747, rs1114167709, rs1114167694, rs786204048, rs1114167771, rs1114167794, rs1114167714, rs765411990, rs587782862, rs1114167773, rs1114167724, rs1114167707, rs1114167782, rs1114167793, rs1114167767, rs766905993, rs1114167723, rs1114167755, rs752404604, rs1114167706, rs1114167717, rs1114167783, rs1114167760, rs1553333599, rs1553333615, rs1553333644, rs1114167790, rs587779297, rs1553351549, rs753075410, rs63751271, rs371776176, rs63750689, rs1553369164, rs202145681, rs1553370310, rs1230083633, rs1553412966, rs1553413710, rs1348956744, rs1553331290, rs1553333421, rs1553333598, rs1416452389, rs1553333707, rs1553641362, rs63751448, rs1553648058, rs587778937, rs1553662753, rs1554292880, rs988423880, rs1553353114, rs63751119, rs1553647995, rs1553663750, rs1458321358, rs730881919, rs1553413178, rs63750443, rs63751596, rs1554309086, rs1553348794, rs1553348882, rs1553348898, rs1553348901, rs1553370371, rs1553365799, rs1553370431, rs1553366510, rs1553408158, rs1553366680, rs1553370404, rs1553411419, rs1553408136, rs1553412397, rs869040863, rs1553348842, rs1553348904, rs1553413599, rs1553413655, rs1553413732, rs1553414022, rs767021188, rs1553350966, rs1553412409, rs796532309, rs587779064, rs1553365711, rs1553333017, rs1553412649, rs1553333175, rs1553333301, rs1553333605, rs1553369100, rs1553369131, rs1553331722, rs1324100572, rs1553332776, rs761037236, rs1553412755, rs1553333438, rs1553333449, rs1553412835, rs1553412735, rs1553413424, rs1553414131, rs1553331337, rs1553332297, rs773262801, rs1553333185, rs1553331454, rs1553332151, rs1553333530, rs1553333633, rs587779285, rs1553333310, rs1553333321, rs1553333497, rs1553646681, rs1553647894, rs1553648195, rs1553653158, rs550890395, rs1064796057, rs1553651130, rs1553662800, rs1553665467, rs1553642079, rs1553648023, rs587782087, rs746536721, rs1553653037, rs1248251121, rs1553646602, rs1553652930, rs1434898623, rs1553665683, rs1554298087, rs1554295967, rs1554297040, rs1554298741, rs1554294393, rs1554297523, rs1554293920, rs1554301486, rs1554304974, rs1553348896, rs1553368675, rs1203462814, rs1553369665, rs1553350721, rs1553369812, rs1553361261, rs1553370443, rs1553408388, rs1553413717, rs63749973, rs1553412064, rs1553408467, rs267608062, rs765873566, rs730881815, rs1553414578, rs1553331665, rs1553331366, rs1553332166, rs1553413663, rs1553332622, rs1553333164, rs63751137, rs1553642777, rs1553648068, rs1553332733, rs1553644123, rs1553648149, rs1302248679, rs1553658009, rs1553665977, rs1416171624, rs1553663834, rs1553664702, rs1553647969, rs1437454428, rs1231406078, rs1554293991, rs1554297488, rs1554297534, rs1064794577, rs1554297764, rs1554298082, rs876661256, rs1554298056, rs1554293810, rs939641251, rs1554304979, rs1554297058, rs1554298067, rs1554306288, rs151244108, rs1553412129, rs1054003194, rs1553412824, rs1553413253, rs1553332671, rs1553333168, rs1553333700, rs63751101, rs1553646764, rs1554300689, rs1554297877, rs1437858319, rs1432436629, rs1553648225, rs1553352462, rs1553332772, rs1553648201, rs1553333635, rs1554297125, rs753256070, rs1553414092, rs587779923, rs1554297962, rs1553361162, rs1554294448, rs1553412495, rs1253275403, rs1553350167, rs267607937, rs1553361231, rs730881755, rs1553408306, rs1553365719, rs1553370366, rs1553370397, rs1553412441, rs1553412960, rs1553411391, rs770110491, rs1553350466, rs1553350758, rs1553413116, rs1553413294, rs1553413074, rs1553361289, rs1553413640, rs1553413784, rs1553414488, rs1553331242, rs1553410300, rs1553414498, rs1553332312, rs1553412502, rs1114167705, rs1553331659, rs1553332768, rs1553414102, rs1553414395, rs1553414519, rs1553331228, rs1553333674, rs1553638868, rs1553663981, rs1553644277, rs1553665866, rs1554297082, rs1554297564, rs1394474494, rs1554293959, rs587782175, rs1554297285, rs1554298786, rs1553356605, rs1553356700, rs1553369034, rs1553370435, rs1553413305, rs1553331304, rs1553652883, rs63751435, rs1553653195, rs1553662622, rs1554293975, rs1554297164, rs1554297342, rs1554297636, rs1461669945, rs1553658104, rs1553350250, rs1553410230, rs1554304745, rs1554298756, rs1553648220, rs1559543768, rs745487791, rs1558438591, rs1558508067, rs1558508343, rs1558645195, rs1558658971, rs1558661368, rs1558663954, rs1558390582, rs1558392228, rs1558461615, rs1558466434, rs1558519611, rs1558521949, rs1558644886, rs587782101, rs1558661380, rs1558662873, rs1558392033, rs1558394093, rs1559544064, rs63750584, rs1558459096, rs1060501994, rs63751667, rs878853704, rs1558665297, rs1558387361, rs1558393006, rs1558394104, rs1559524070, rs1559530646, rs1553645226, rs1559551570, rs1559575107, rs1559597322, rs1558451119, rs1558459882, rs1558478567, rs1562605623, rs1562614946, rs781078805, rs1558644683, rs1558658980, rs1558659056, rs1558659699, rs1558667222, rs1558668156, rs1558668258, rs1558393070, rs1558394336, rs1562626204, rs1562629003, rs1562632035, rs587782602, rs1562634737, rs1562635799, rs1562669585, rs1060500702, rs1559539489, rs1559553501, rs1562616355, rs1562644987, rs764171734, rs1562711587, rs1562598658, rs1562604682, rs1562664845, rs1562678257, rs1558666177, rs1562633172, rs1559558071, rs1261282733, rs63750832, rs587778978, rs1064795063, rs1558511051, rs63751097, rs765763906, rs1562626070, rs1562671039, rs1558518588, rs1558461683, rs63751115, rs1558644995, rs1558659265, rs1558660612, rs1559521039, rs1559574795, rs1562626011, rs1562636427, rs1559578422, rs772491283, rs1573424223, rs730881784, rs1573446614, rs1573451108, rs1558464008, rs1573484655, rs1573566217, rs1573566488, rs1573567212, rs63750078, rs1573567340, rs1573567537, rs1573567630, rs1573569948, rs1573570621, rs1573574086, rs1573578423, rs1573578439, rs1573579206, rs1572698011, rs1572708636, rs1473648816, rs1276159036, rs1572716371, rs1572719776, rs1572719974, rs1572720016, rs1572720562, rs1572720704, rs778555956, rs1553412720, rs1572723270, rs1572723640, rs587779221, rs1572725436, rs1572725803, rs1572726309, rs1572726468, rs63750985, rs1572727440, rs1572727797, rs1572729033, rs367758473, rs587779253, rs1572730002, rs1572730065, rs1315445200, rs1572735072, rs1572735943, rs1572738865, rs1572745157, rs754469538, rs1572746365, rs1572747837, rs1575376458, rs1575376830, rs1575395515, rs63750507, rs1575469070, rs1575481212, rs1575537843, rs1575620443, rs1575621386, rs1575621506, rs63750740, rs1386031101, rs1575640892, rs1583285552, rs1583299686, rs1583318494, rs1583320992, rs1243063129, rs757679199, rs1583375182, rs762387250, rs36038802, rs267608035, rs1572716545, rs1572739097, rs1575628928, rs746306598, rs1572747278, rs1572747685, rs1583374709, rs1572708580, rs1572736122, rs1575414321, rs1573437173, rs1573456772, rs1583316404, rs1583363851, rs1572727176, rs1573423412, rs1573440880, rs1573442100, rs369670665, rs1573451078, rs1573547745, rs1573548065, rs1573553636, rs1573567132, rs63750234, rs63751409, rs138465383, rs1573573619, rs1572720192, rs1572720794, rs1572722737, rs1572723723, rs1572725235, rs745483465, rs1572728039, rs1572728112, rs1572728472, rs1572729161, rs1175196087, rs1572736128, rs1572738533, rs1572739043, rs891318615, rs1572741984, rs1572745084, rs1572746382, rs1572746488, rs1060504739, rs1575414904, rs1575448385, rs1575469505, rs1466223609, rs63750198, rs1575639851, rs1575640960, rs1583269216, rs1583285344, rs1583319050, rs1583334346, rs1562651617, rs1583410315, rs767028531, rs1573566175, rs1572739119, rs1572746025, rs1575449402, rs1325835006, rs1672250353, rs1672664863, rs1672951706, rs1673066717, rs1673067879, rs1673070318, rs1666728055, rs1667076589, rs63751433, rs1667245819, rs1667245915, rs1667313093, rs1667395869, rs1667504677, rs1668118988, rs1668692410, rs587779313, rs1669058948, rs1669059418, rs1669245178, rs1669252923, rs1669287624, rs1007311950, rs1669354866, rs1669364351, rs1669365820, rs41295270, rs1669441162, rs1669445829, rs1669451548, rs1669467747, rs1669486855, rs1669487701, rs1669491751, rs1669493890, rs1669760609, rs1669874125, rs1670044220, rs1670120965, rs2080898853, rs2080899985, rs2081922847, rs2083403132, rs2083405700, rs2085310643, rs2085311497, rs2085415927, rs2085469647, rs1782934080, rs1782947222, rs1782958183, rs1782962828, rs1064793426, rs63750456, rs1783004175, rs1783147885, rs1783516106, rs1344095646, rs1784299649, rs1784536095, rs1784802468, rs1784806713, rs1221485925, rs1299958102, rs1669882321, rs2082517369, rs1673083690, rs1667266283, rs1307026290, rs1672953209, rs1667575488	15814641
Hypertrophic cardiomyopathy	Hypertrophic Cardiomyopathy, Hypertrophic obstructive cardiomyopathy	rs63750743, rs104894655, rs121908987, rs587776643, rs28938173, rs121908989, rs121908991, rs267606977, rs267606978, rs193922384, rs121909374, rs886041030, rs886041031, rs121909375, rs121909377, rs2856655, rs587776700, rs387906397, rs104894204, rs121434470, rs104894828, rs121964855, rs121964856, rs121964858, rs74315380, rs104894724, rs104894725, rs104894727, rs104894728, rs104894729, rs104894730, rs267607127, rs2147283135, rs267607128, rs267607125, rs104894502, rs104894503, rs104894504, rs28933405, rs111033560, rs121434594, rs80338797, rs104893748, rs104894368, rs104894369, rs104894370, rs121913624, rs3218713, rs121913625, rs121913626, rs121913627, rs121913628, rs121913629, rs121913630, rs121913631, rs121913632, rs121913633, rs121913634, rs3218714, rs121913636, rs121913637, rs121913638, rs121913639, rs121913641, rs121913642, rs121913643, rs121913647, rs121913650, rs121913651, rs36211715, rs121913654, rs267606911, rs267606908, rs730880850, rs121912675, rs267606629, rs193922680, rs1600482909, rs387906898, rs199476398, rs387907079, rs199474815, rs199474703, rs199476305, rs199476306, rs199476315, rs199476316, rs199476317, rs199476321, rs199476311, rs193922649, rs36211723, rs187830361, rs193922383, rs193922386, rs193922390, rs193922697, rs387907267, rs397507520, rs727505017, rs397515888, rs397515889, rs397515891, rs397515893, rs397515894, rs397515895, rs397515896, rs397515897, rs397515903, rs397515905, rs375882485, rs397515907, rs397515910, rs397515912, rs397515916, rs397515920, rs397515925, rs397515926, rs397515931, rs397515933, rs397515934, rs397515935, rs397515937, rs397515942, rs397515943, rs397515944, rs397515947, rs397515948, rs397515952, rs397515954, rs112738974, rs111729952, rs397515960, rs397515963, rs397515965, rs397515966, rs397515970, rs397515972, rs397515973, rs397515974, rs397515975, rs397515977, rs376395543, rs397515979, rs397515982, rs397515987, rs397515990, rs397515991, rs397515992, rs397515995, rs397515997, rs397516001, rs397516005, rs113358486, rs397516006, rs397516007, rs397516008, rs397516010, rs397516013, rs397516014, rs373746463, rs397516019, rs397516020, rs397516022, rs397516023, rs397516029, rs397516031, rs397516032, rs397516035, rs397516037, rs397516038, rs397516040, rs397516042, rs397516044, rs397516047, rs397516049, rs397516052, rs397516056, rs397516057, rs397516058, rs397516059, rs397516061, rs397516067, rs397516068, rs397516070, rs397516072, rs397516073, rs397516074, rs397516076, rs397516077, rs397516080, rs201078659, rs397516082, rs397516083, rs1555122751, rs397516088, rs397516089, rs397516095, rs397516098, rs397516101, rs397516103, rs397516110, rs397516127, rs371898076, rs397516132, rs397516134, rs397516142, rs3218716, rs397516153, rs397516154, rs397516155, rs397516156, rs397516157, rs397516160, rs397516161, rs397516165, rs397516166, rs397516170, rs397516171, rs397516172, rs397516178, rs397516179, rs397516187, rs397516201, rs397516202, rs145213771, rs397516207, rs397516209, rs397516212, rs397516238, rs397516248, rs397516254, rs397516258, rs397516260, rs45516091, rs397516264, rs397516266, rs397516269, rs397516340, rs397516347, rs121917760, rs397516349, rs397516353, rs397516354, rs397516355, rs397516357, rs397516373, rs397516406, rs397516455, rs397516456, rs397516457, rs397516463, rs397516464, rs45525839, rs397516470, rs397516471, rs45578238, rs111377893, rs397516736, rs397516738, rs397516739, rs397516751, rs397516752, rs397516784, rs397517283, rs397514752, rs143697995, rs267607490, rs199472948, rs138193236, rs398123279, rs869320740, rs606231340, rs606231324, rs587779392, rs587779393, rs587782951, rs587782957, rs587782958, rs587782962, rs587782965, rs138049878, rs376897125, rs368765949, rs727504247, rs376923877, rs727504277, rs727504255, rs727504246, rs727504331, rs727503513, rs727504392, rs397516039, rs727504271, rs727504321, rs727504289, rs727504305, rs727503172, rs573821685, rs727503176, rs727503178, rs727504423, rs727503180, rs727504333, rs727503182, rs727504265, rs727503184, rs727503186, rs727503187, rs727504252, rs727504864, rs727504334, rs727503192, rs397515932, rs727504366, rs727504248, rs727504287, rs200411226, rs727503204, rs727504329, rs727504269, rs573916965, rs367947846, rs727503210, rs730880335, rs727503166, rs727504390, rs730880361, rs727504276, rs111683277, rs727503174, rs727503175, rs727504349, rs727504314, rs727504371, rs730880341, rs727504293, rs727503195, rs111437311, rs727503202, rs727503203, rs727504279, rs727505152, rs727503209, rs727503211, rs727503212, rs727503217, rs727503219, rs730880366, rs727503220, rs727504356, rs727504311, rs727503261, rs727503264, rs727504238, rs148808089, rs727503271, rs727504409, rs727503276, rs727504283, rs727503296, rs45544633, rs727503246, rs727503252, rs727503253, rs202141173, rs2754158, rs727504310, rs727503260, rs727504272, rs727504240, rs727503263, rs727504239, rs727504925, rs727504237, rs727504236, rs727505202, rs727504267, rs727503278, rs727504243, rs727504285, rs727503499, rs727503504, rs727504242, rs727504264, rs727504275, rs727503500, rs727503503, rs727503120, rs730880336, rs730880337, rs730880362, rs730880210, rs730880143, rs730880159, rs730881116, rs730881122, rs730880162, rs730880605, rs730880604, rs730880600, rs730880702, rs730880598, rs730880597, rs730880699, rs730880592, rs730880675, rs730880720, rs730880719, rs730880672, rs730880668, rs730880718, rs730880666, rs730880586, rs730880584, rs11570112, rs730880578, rs730880576, rs730880660, rs730880657, rs730880655, rs730880654, rs730880653, rs730880652, rs730880714, rs730880651, rs730880558, rs730880649, rs730880647, rs730880713, rs730880646, rs730880546, rs727503197, rs730880695, rs730880644, rs730880640, rs730880712, rs730880544, rs730880542, rs730880541, rs730880538, rs730880533, rs730880531, rs730880641, rs730880639, rs397515890, rs730880724, rs730880635, rs730880723, rs730880686, rs730880631, rs730880678, rs730880629, rs730880684, rs368121566, rs730880621, rs730880681, rs375607980, rs730880618, rs730880680, rs730880679, rs730880677, rs730880704, rs730880703, rs730880721, rs730880698, rs730880664, rs730880663, rs730880662, rs730880659, rs730880916, rs727504558, rs730880759, rs730880756, rs730880750, rs730880749, rs730880748, rs730880736, rs727504241, rs727504299, rs730880732, rs730880883, rs730880930, rs730880929, rs730880875, rs370310929, rs730880926, rs730880864, rs730880856, rs397516268, rs730880922, rs730880845, rs730880388, rs730881091, rs786204352, rs786204339, rs786204338, rs786204336, rs786204329, rs2069544, rs281865416, rs773317399, rs121913648, rs730880809, rs863224483, rs863224899, rs863224900, rs863225120, rs863225121, rs863225107, rs863225114, rs863225113, rs863225104, rs863225105, rs863225112, rs863225106, rs863225109, rs863225111, rs863225100, rs863225103, rs863225102, rs863225097, rs863225101, rs730880876, rs863225272, rs863225271, rs190228518, rs863225269, rs761507504, rs864622224, rs1057515421, rs869025470, rs869025469, rs869025461, rs869025468, rs869025460, rs869025467, rs869025466, rs869025465, rs869025464, rs869025463, rs869025459, rs869025462, rs727503512, rs876657706, rs876657705, rs876657703, rs876657702, rs727503213, rs876657884, rs878854428, rs878853831, rs878853842, rs1562999443, rs1563003848, rs1562991002, rs879255639, rs886037900, rs886037902, rs886037901, rs886038822, rs886039030, rs886039185, rs754664923, rs141019458, rs1057517766, rs1057517767, rs779650200, rs1057518030, rs1057517711, rs1057519503, rs1057520814, rs1060499673, rs1060501480, rs1060501484, rs1060501481, rs1060501478, rs1064792936, rs1060501475, rs1060501479, rs1064792935, rs1060501436, rs1060501448, rs1060501443, rs1060501452, rs1060505018, rs1060499604, rs781135153, rs1064796231, rs1064793202, rs977277400, rs1064793429, rs771929829, rs745811346, rs1114167419, rs1114167361, rs1555409659, rs1555123389, rs1131691514, rs1131692185, rs1131692058, rs1553279294, rs1555120920, rs1555121924, rs1555338319, rs1555120300, rs1555121488, rs373792537, rs1444727212, rs1555338462, rs1555120937, rs1555123629, rs794727046, rs1555123633, rs1555121172, rs1555123438, rs1555336467, rs1555338658, rs1213930919, rs1432810664, rs1555122188, rs764743402, rs974671846, rs1420159591, rs745688425, rs1555338080, rs200889953, rs1555120258, rs1298025872, rs767039057, rs1555120529, rs1555121247, rs774521272, rs1555122156, rs1555123473, rs1555123496, rs1555123597, rs1555337701, rs2856897, rs869312381, rs1555122928, rs1555123743, rs1554401581, rs1555120651, rs868819340, rs1555122053, rs730880742, rs758891557, rs1555337794, rs1555338378, rs1555338758, rs1245885836, rs1566530698, rs1566513862, rs1565629792, rs730880751, rs727504294, rs1563001548, rs1565622952, rs1565625473, rs1565626409, rs1565627536, rs1565628062, rs1565628486, rs1565631430, rs1391622163, rs1131691685, rs749007293, rs1566535491, rs1565624090, rs1565625777, rs1565631428, rs1568858210, rs1566537070, rs1565627566, rs1567864804, rs1563161306, rs1565622703, rs190765116, rs1595843598, rs1565625795, rs1565628078, rs774316050, rs1565631381, rs1565631424, rs1566531421, rs730880872, rs730880870, rs1566536418, rs1566536436, rs1565623216, rs1265248322, rs113276889, rs1562998062, rs1419032418, rs1565627615, rs1565624196, rs1595843640, rs1595846398, rs764950910, rs1600448065, rs1600462474, rs1417887060, rs1600477808, rs1600480573, rs1050997719, rs1420394583, rs1595840648, rs1595841063, rs1595843549, rs1595843758, rs1595845565, rs1595845888, rs1595846344, rs1595846475, rs1595849931, rs1595070747, rs1246272841, rs730880741, rs1173617248, rs1595085409, rs730880879, rs1299079662, rs1595848628, rs1595849603, rs1450218521, rs1571627587, rs1603037717, rs1603038411, rs1595850762, rs777702465, rs1595841736, rs1595842238, rs1595845204, rs1025692267, rs1595070689, rs1198682781, rs2095879705, rs201911056, rs727504425, rs141414377, rs1596303148, rs1595841206, rs1595844714, rs1595842632, rs1595843828, rs113709679, rs1595841552, rs1595849742, rs754529157, rs1709195189, rs1342121466, rs2095880935, rs2095883508, rs2095884984, rs2095889902, rs2095891411, rs2095898532, rs780625785, rs1892592854, rs1892948780, rs2095879167, rs1956121988, rs2095893477, rs2095894178, rs1801002279, rs1892956157	9527842

Unknown
Disease term	Disease name	Evidence	References	Source
Myocardial Infarction	Myocardial Infarction			GWAS

Associations from Text Mining
Disease Name	Relationship Type	References
Adenocarcinoma	Associate	1325827, 9823779
Adenocarcinoma	Stimulate	15334673
Adenocarcinoma Follicular	Associate	25048347
Adenocarcinoma of Lung	Associate	29522283, 32795291, 7928630
Adenoma	Stimulate	27222072
Adenomatous Polyps	Associate	17278192
Allan Herndon Dudley syndrome	Stimulate	9555115
Alzheimer Disease	Associate	25311278, 30268934, 36142676
Arthritis Rheumatoid	Inhibit	8660103
Asthma	Associate	39217320
Ataxia Telangiectasia	Associate	16891807
Autoimmune Diseases	Associate	30268934
Bloom Syndrome	Stimulate	36293204
Bone Neoplasms	Associate	7593131
Brain Neoplasms	Inhibit	15592684, 8641989
Breast Neoplasms	Associate	10082974, 1356959, 15592684, 15684389, 1714241, 17591363, 18676749, 21738817, 21838876, 22290468, 22451184, 23818346, 29203642, 31839604, 33402463, 34876614, 35939247, 8104920, 8855975, 9038158, 9569056
Breast Neoplasms	Inhibit	11694515, 12163590, 16415009, 16631833, 17695492, 25048347, 28991262, 33436746, 8394105
Burkitt Lymphoma	Associate	12515726
Burkitt Lymphoma	Inhibit	16415009
Calcinosis Cutis	Associate	11337376, 15592684, 18661008, 19414372, 7981081
Calcinosis Cutis	Inhibit	12163590
Carcinogenesis	Associate	12801264, 17359290, 32795291, 9569056
Carcinoma Ductal	Associate	1714241
Carcinoma Ductal Breast	Associate	1714241, 23725501
Carcinoma Hepatocellular	Associate	15761980, 20841469, 25472720, 29271183, 35438846
Carcinoma in Situ	Associate	20841469
Carcinoma Intraductal Noninfiltrating	Inhibit	1714241
Carcinoma Non Small Cell Lung	Associate	10733773, 11267948, 11896068, 19152459
Carcinoma Ovarian Epithelial	Associate	10817501, 12950146, 7669582
Carcinoma Renal Cell	Associate	20515575, 7614395, 8593205, 9341897
Carcinoma Squamous Cell	Associate	17359290
Central Nervous System Diseases	Associate	36430274
Cerebral Intraventricular Hemorrhage	Associate	36430274
Cholangiocarcinoma	Associate	29271183
Chondrosarcoma	Associate	7593131
Colonic Diseases	Associate	20841469
Colonic Neoplasms	Associate	15563674, 16425351, 20841469, 7981087
Colorectal Neoplasms	Associate	10450731, 15334673, 15563674, 16554912, 17278192, 19125701, 21225146, 23679306, 27888614, 29700912, 7947079, 7947085, 7981087, 8217591, 8549951
Colorectal Neoplasms	Stimulate	27222072
Digestive System Neoplasms	Associate	18810774
Endometrial Neoplasms	Associate	30827726, 8855975
Endometriosis	Associate	24133580
Epstein Barr Virus Infections	Associate	16415009
Esophageal Neoplasms	Associate	17708612
Esophageal Squamous Cell Carcinoma	Associate	10507772, 11027435, 11319942
Fetal Growth Retardation	Associate	36293204, 36430274
Fetal Growth Retardation	Stimulate	36768287
Fibrosarcoma	Associate	16814409
Gastrointestinal Diseases	Associate	19152459
Gastrointestinal Neoplasms	Associate	19152459
Glioma	Inhibit	16475705
Glioma	Associate	17057884, 33721446
Hematologic Neoplasms	Stimulate	10910925, 16232196
Hereditary Breast and Ovarian Cancer Syndrome	Associate	8855975
Hereditary leiomyomatosis and renal cell cancer	Associate	18647967
Hodgkin Disease	Associate	18647967, 8956779
Hydatidiform Mole	Associate	15228429
Hypopharyngeal Neoplasms	Associate	9555115
Ichthyosis prematurity syndrome	Associate	36768287
Kidney Neoplasms	Associate	7614395
Laryngeal Neoplasms	Associate	9555115
Laryngitis	Associate	9555115
Leukemia	Associate	10910925, 1311721, 7612661
Leukemia Monocytic Acute	Associate	9490665
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	9490665
Leukemia Myeloid	Inhibit	9490665
Leukemia Myeloid Acute	Associate	10910925, 1311721, 33284559, 9490665, 9649149
Lewy Body Disease	Associate	30448004
Liver Cirrhosis	Associate	20841469
Liver Failure	Associate	10450731
Lung Neoplasms	Associate	29970055, 32795291, 7928630
Lymphatic Metastasis	Associate	15040016, 15150613, 15334673, 16425351, 16554912, 22903495, 23679306, 23725501, 24858271, 32795291, 7669582, 7903963, 7981081, 8924224
Lymphatic Metastasis	Inhibit	17504447, 18810774, 29187211
Lymphoma	Associate	14616965, 28991262, 8956779
Lymphoma Follicular	Stimulate	18647967
Lymphoma Non Hodgkin	Associate	14616965, 16891807
Lymphoma Non Hodgkin	Stimulate	8956779
Lymphoma T Cell Peripheral	Associate	14616965
Medulloblastoma	Associate	39251709
Melanoma	Inhibit	11694515, 28991262, 8394105
Melanoma	Associate	19152459, 25048347, 25808322, 30396920, 31462745, 32824412, 7981081, 8648172, 8855975
Mesothelioma	Associate	19662092
Mitochondrial Diseases	Stimulate	34876614
Myelodysplastic Syndromes	Associate	10910925
Neoplasm Invasiveness	Associate	22451184
Neoplasm Metastasis	Associate	10450731, 10507772, 10631462, 11267948, 12628186, 1311721, 14960567, 15040016, 16425351, 16475705, 16537673, 17278192, 18676749, 20713695, 22451184, 23679306, 25957329, 26716410, 29863788, 37731021, 7612661, 7902105, 7947085, 8132589, 8389529, 8593205, 8924224, 8956779, 9823779
Neoplasm Metastasis	Inhibit	11337376, 11694515, 11896068, 12105213, 12192599, 12490715, 14998490, 15181008, 15563674, 15592684, 15650182, 15684389, 16140886, 16277028, 16415009, 16631833, 16814409, 17314099, 17504447, 17591363, 17695492, 17708612, 18408655, 19152459, 19331130, 19662092, 20448457, 2056128, 20602252, 20841469, 21270158, 21838876, 22290468, 22691413, 23725501, 24133580, 24260116, 25048347, 25686823, 25808322, 28376369, 28656791, 28991262, 30396920, 32824412, 33436746, 34156643, 35939247, 7981087, 8096503, 8217591, 8394105, 8529641, 8641989, 8660103, 8956793, 9099969, 9514051, 9569056
Neoplasm Seeding	Associate	18408655
Neoplasms	Associate	10428867, 10817501, 11027435, 11121025, 11208341, 11267948, 11896068, 12950146, 1311721, 14998490, 15040016, 15150613, 15228429, 15650182, 15785755, 16425351, 16442775, 16537673, 16814409, 16891807, 17155928, 17278192, 17359290, 17433065, 17708612, 19125701, 19152459, 20713695, 21270158, 23679306, 23725501, 24858271, 25957329, 27222072, 28962550, 28991262, 29700912, 29970055, 30827726, 32795291, 33402463, 35939247, 37731021, 7614395, 7669582, 7928630, 7947079, 7981087, 8030752, 8389529, 8593205, 8641989, 8912537, 8932344, 8956779, 9514051, 9555115, 9569056, 9823779
Neoplasms	Inhibit	11337376, 15563674, 16277028, 17532757, 18810774, 20841469, 24811176, 28376369, 30396920, 33436746, 7734302, 8549951, 8648172, 9443089
Neoplasms	Stimulate	31462745
Neoplasms Cystic Mucinous and Serous	Associate	7669582
Nerve Degeneration	Associate	36430274
Neuroblastoma	Associate	10400630, 16232196, 16442775, 17155928, 19186179, 2056128, 21573212, 22328561, 28991262, 8932344, 9038158, 9188446
Neurofibrosarcoma	Associate	19414372
Neurologic Manifestations	Associate	36430274
Non Muscle Invasive Bladder Neoplasms	Associate	19171060, 8104920
Osteosarcoma	Associate	7593131
Ovarian Diseases	Associate	19152459
Ovarian Neoplasms	Associate	10631462, 10817501, 12950146, 17433065, 18408655, 19152459, 19487548, 21469425, 7669582
Personality Disorders	Associate	12950146
Prodromal Symptoms	Associate	10733773, 29700912
Prostatic Hyperplasia	Associate	7693635
Prostatic Neoplasms	Associate	24858271
Prostatitis	Associate	19152459, 7693635
Sarcoma	Associate	9099969
Sarcoma Kaposi	Associate	21270158
Sick Sinus Syndrome	Inhibit	8389529
Small Cell Lung Carcinoma	Associate	10219898
Squamous Cell Carcinoma of Head and Neck	Associate	11337376, 15150613, 25277180, 29187211, 35655921
Squamous Intraepithelial Lesions	Associate	12801264
Stomach Neoplasms	Associate	15040016, 16425351, 17504447, 17532757, 17695492, 20205286, 22799386, 22903495, 23725501, 37402315, 7902105, 8096503, 8641989, 8924224
Tertiary Lymphoid Structures	Inhibit	16277028, 23012578, 8641989, 8855975
Tertiary Lymphoid Structures	Associate	16425351, 33402463
Thymoma	Associate	12049674
Thyroid Cancer Papillary	Inhibit	8389529
Thyroid Carcinoma Anaplastic	Associate	8394105
Thyroid Neoplasms	Associate	25048347, 8030752, 8394105
Urinary Bladder Neoplasms	Associate	19171060, 7614395
Uterine Cervical Dysplasia	Inhibit	16537673
Uterine Cervical Neoplasms	Associate	16537673, 17359290, 26716410, 8855975
Uterine Cervicitis	Associate	9823779
Uterine Neoplasms	Associate	8855975
Uveal melanoma	Associate	34782661