LRRC18 (leucine rich repeat containing 18)

Gene

• Entrez ID: 474354
• Gene name: Leucine rich repeat containing 18
• Gene symbol: LRRC18
• Synonyms (NCBI Gene): UNQ933, UNQ9338, VKGE9338
• Chromosome: 10
• Chromosome location: 10q11.23

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1118996	hsa-miR-1321	CLIP-seq
MIRT1118997	hsa-miR-3150b-3p	CLIP-seq
MIRT1118998	hsa-miR-3165	CLIP-seq
MIRT1118999	hsa-miR-3179	CLIP-seq
MIRT1119000	hsa-miR-3190	CLIP-seq
MIRT1119001	hsa-miR-3202	CLIP-seq
MIRT1119002	hsa-miR-3689d	CLIP-seq
MIRT1119003	hsa-miR-4419a	CLIP-seq
MIRT1119004	hsa-miR-4436b-5p	CLIP-seq
MIRT1119005	hsa-miR-4480	CLIP-seq
MIRT1119006	hsa-miR-4510	CLIP-seq
MIRT1119007	hsa-miR-4533	CLIP-seq
MIRT1119008	hsa-miR-4739	CLIP-seq
MIRT1119009	hsa-miR-4756-5p	CLIP-seq
MIRT1119010	hsa-miR-4784	CLIP-seq
MIRT1119011	hsa-miR-939	CLIP-seq
MIRT1920599	hsa-miR-193a-3p	CLIP-seq
MIRT1920600	hsa-miR-193b	CLIP-seq
MIRT1920601	hsa-miR-513a-3p	CLIP-seq
MIRT1920602	hsa-miR-892b	CLIP-seq
MIRT1920599	hsa-miR-193a-3p	CLIP-seq
MIRT1920600	hsa-miR-193b	CLIP-seq
MIRT1920601	hsa-miR-513a-3p	CLIP-seq
MIRT1920602	hsa-miR-892b	CLIP-seq
MIRT1920599	hsa-miR-193a-3p	CLIP-seq
MIRT1920600	hsa-miR-193b	CLIP-seq
MIRT1920601	hsa-miR-513a-3p	CLIP-seq
MIRT1920602	hsa-miR-892b	CLIP-seq
MIRT2033669	hsa-miR-759	CLIP-seq
MIRT1118998	hsa-miR-3165	CLIP-seq
MIRT1118999	hsa-miR-3179	CLIP-seq
MIRT1119000	hsa-miR-3190	CLIP-seq
MIRT1119001	hsa-miR-3202	CLIP-seq
MIRT1119004	hsa-miR-4436b-5p	CLIP-seq
MIRT1119007	hsa-miR-4533	CLIP-seq
MIRT2453322	hsa-miR-3074-3p	CLIP-seq
MIRT1118998	hsa-miR-3165	CLIP-seq
MIRT1118999	hsa-miR-3179	CLIP-seq
MIRT1119000	hsa-miR-3190	CLIP-seq
MIRT1119001	hsa-miR-3202	CLIP-seq
MIRT2453323	hsa-miR-365	CLIP-seq
MIRT1119004	hsa-miR-4436b-5p	CLIP-seq
MIRT1119007	hsa-miR-4533	CLIP-seq
MIRT2684180	hsa-miR-216a	CLIP-seq
MIRT2684181	hsa-miR-4450	CLIP-seq
MIRT2684182	hsa-miR-4667-5p	CLIP-seq
MIRT2684183	hsa-miR-4700-5p	CLIP-seq
MIRT2684184	hsa-miR-4762-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005737	Component	Cytoplasm	IEA
GO:0035556	Process	Intracellular signal transduction	IBA

Other IDs

• MIM: 619002
• HGNC: 23199
• e!Ensembl: ENSG00000165383

Protein

• UniProt ID: Q8N456
• Protein name: Leucine-rich repeat-containing protein 18
• Protein function: May be involved in the regulation of spermatogenesis and sperm maturation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13855	LRR_8	30 → 85	Leucine rich repeat	Repeat
  PF13855	LRR_8	50 → 108	Leucine rich repeat	Repeat
  PF13855	LRR_8	73 → 133	Leucine rich repeat	Repeat

• Sequence:

  MVKGEKGPKGKKITLKVARNCIKITFDGKKRLDLSKMGITTFPKCILRLSDMDELDLSRN
  LIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSLLYLNVSNNRLTSNGLPVELKQL
  KNIRAVNLGLNHLDSVPTTLGALKELHEVGLHDNLLNNIPVSISKLPKLKKLNIKRNPFP
  KPGESEIFIDSIRRLENLYVVEEKDLCAACLRKCQNARDNLNRIKNMATTTPRKTIFPNL
  ISPNSMAKDSWEDWRIRLTSS

• Sequence length: 261