Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	474354
Gene name Gene Name - the full gene name approved by the HGNC.	Leucine rich repeat containing 18
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LRRC18
Synonyms (NCBI Gene) Gene synonyms aliases	UNQ933, UNQ9338, VKGE9338
Chromosome Chromosome number	10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	10q11.23

Show/Hide all(48)

miRTarBase ID	miRNA	Experiments
MIRT1118996	hsa-miR-1321	CLIP-seq
MIRT1118997	hsa-miR-3150b-3p	CLIP-seq
MIRT1118998	hsa-miR-3165	CLIP-seq
MIRT1118999	hsa-miR-3179	CLIP-seq
MIRT1119000	hsa-miR-3190	CLIP-seq
MIRT1119001	hsa-miR-3202	CLIP-seq
MIRT1119002	hsa-miR-3689d	CLIP-seq
MIRT1119003	hsa-miR-4419a	CLIP-seq
MIRT1119004	hsa-miR-4436b-5p	CLIP-seq
MIRT1119005	hsa-miR-4480	CLIP-seq
MIRT1119006	hsa-miR-4510	CLIP-seq
MIRT1119007	hsa-miR-4533	CLIP-seq
MIRT1119008	hsa-miR-4739	CLIP-seq
MIRT1119009	hsa-miR-4756-5p	CLIP-seq
MIRT1119010	hsa-miR-4784	CLIP-seq
MIRT1119011	hsa-miR-939	CLIP-seq
MIRT1920599	hsa-miR-193a-3p	CLIP-seq
MIRT1920600	hsa-miR-193b	CLIP-seq
MIRT1920601	hsa-miR-513a-3p	CLIP-seq
MIRT1920602	hsa-miR-892b	CLIP-seq
MIRT1920599	hsa-miR-193a-3p	CLIP-seq
MIRT1920600	hsa-miR-193b	CLIP-seq
MIRT1920601	hsa-miR-513a-3p	CLIP-seq
MIRT1920602	hsa-miR-892b	CLIP-seq
MIRT1920599	hsa-miR-193a-3p	CLIP-seq
MIRT1920600	hsa-miR-193b	CLIP-seq
MIRT1920601	hsa-miR-513a-3p	CLIP-seq
MIRT1920602	hsa-miR-892b	CLIP-seq
MIRT2033669	hsa-miR-759	CLIP-seq
MIRT1118998	hsa-miR-3165	CLIP-seq
MIRT1118999	hsa-miR-3179	CLIP-seq
MIRT1119000	hsa-miR-3190	CLIP-seq
MIRT1119001	hsa-miR-3202	CLIP-seq
MIRT1119004	hsa-miR-4436b-5p	CLIP-seq
MIRT1119007	hsa-miR-4533	CLIP-seq
MIRT2453322	hsa-miR-3074-3p	CLIP-seq
MIRT1118998	hsa-miR-3165	CLIP-seq
MIRT1118999	hsa-miR-3179	CLIP-seq
MIRT1119000	hsa-miR-3190	CLIP-seq
MIRT1119001	hsa-miR-3202	CLIP-seq
MIRT2453323	hsa-miR-365	CLIP-seq
MIRT1119004	hsa-miR-4436b-5p	CLIP-seq
MIRT1119007	hsa-miR-4533	CLIP-seq
MIRT2684180	hsa-miR-216a	CLIP-seq
MIRT2684181	hsa-miR-4450	CLIP-seq
MIRT2684182	hsa-miR-4667-5p	CLIP-seq
MIRT2684183	hsa-miR-4700-5p	CLIP-seq
MIRT2684184	hsa-miR-4762-5p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005737	Component	Cytoplasm	IEA

MIM	HGNC	e!Ensembl
619002	23199	ENSG00000165383

Protein

UniProt ID

Q8N456

Protein name

Leucine-rich repeat-containing protein 18

Protein function

May be involved in the regulation of spermatogenesis and sperm maturation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13855	LRR_8	30 → 85	Leucine rich repeat	Repeat
PF13855	LRR_8	50 → 108	Leucine rich repeat	Repeat
PF13855	LRR_8	73 → 133	Leucine rich repeat	Repeat

Sequence

MVKGEKGPKGKKITLKVARNCIKITFDGKKRLDLSKMGITTFPKCILRLSDMDELDLSRN
LIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSLLYLNVSNNRLTSNGLPVELKQL
KNIRAVNLGLNHLDSVPTTLGALKELHEVGLHDNLLNNIPVSISKLPKLKKLNIKRNPFP
KPGESEIFIDSIRRLENLYVVEEKDLCAACLRKCQNARDNLNRIKNMATTTPRKTIFPNL
ISPNSMAKDSWEDWRIRLTSS

Sequence length

261

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Rheumatoid arthritis	Rheumatoid Arthritis	rs587776843	19503088

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Systemic lupus erythematosus	Systemic lupus erythematosus			GWAS

Show/Hide Text Mining Associations (2)

Disease Name	Relationship Type	References
Associations from Text Mining
Coronary Artery Disease	Associate	33686958
Pulmonary edema of mountaineers	Associate	35885976

LRRC18 (leucine rich repeat containing 18)