Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	47
Gene name	ATP citrate lyase
Gene symbol	ACLY
Synonyms (NCBI Gene)	ACLATPCLCLATP
Chromosome	17
Chromosome location	17q21.2
Summary	ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acety

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miRTarBase ID	miRNA	Experiments	Reference
MIRT049373	hsa-miR-92a-3p	CLASH	23622248
MIRT049373	hsa-miR-92a-3p	CLASH	23622248
MIRT047450	hsa-miR-10b-5p	CLASH	23622248
MIRT045906	hsa-miR-125b-5p	CLASH	23622248
MIRT045416	hsa-miR-149-5p	CLASH	23622248
MIRT045416	hsa-miR-149-5p	CLASH	23622248
MIRT044080	hsa-miR-361-5p	CLASH	23622248
MIRT042918	hsa-miR-324-3p	CLASH	23622248
MIRT042069	hsa-miR-484	CLASH	23622248
MIRT040866	hsa-miR-18a-3p	CLASH	23622248
MIRT039123	hsa-miR-769-3p	CLASH	23622248
MIRT038850	hsa-miR-93-3p	CLASH	23622248
MIRT038673	hsa-miR-10a-3p	CLASH	23622248
MIRT037071	hsa-miR-877-3p	CLASH	23622248
MIRT036343	hsa-miR-1229-3p	CLASH	23622248
MIRT036222	hsa-miR-320b	CLASH	23622248
MIRT732501	hsa-miR-5580-3p	Microarray	32597160
MIRT756115	hsa-miR-214-3p	Luciferase reporter assayWestern blottingqRT-PCRFlow cytometry	37747441
MIRT762691	hsa-miR-1207-3p	CLIP-seq
MIRT762692	hsa-miR-1244	CLIP-seq
MIRT762693	hsa-miR-1253	CLIP-seq
MIRT762694	hsa-miR-1258	CLIP-seq
MIRT762695	hsa-miR-1275	CLIP-seq
MIRT762696	hsa-miR-1289	CLIP-seq
MIRT762697	hsa-miR-1324	CLIP-seq
MIRT762698	hsa-miR-2116	CLIP-seq
MIRT762699	hsa-miR-22	CLIP-seq
MIRT762700	hsa-miR-27a	CLIP-seq
MIRT762701	hsa-miR-27b	CLIP-seq
MIRT762702	hsa-miR-3152-3p	CLIP-seq
MIRT762703	hsa-miR-3160-5p	CLIP-seq
MIRT762704	hsa-miR-3179	CLIP-seq
MIRT762705	hsa-miR-3189-3p	CLIP-seq
MIRT762706	hsa-miR-3617	CLIP-seq
MIRT762707	hsa-miR-3655	CLIP-seq
MIRT762708	hsa-miR-3691-5p	CLIP-seq
MIRT762709	hsa-miR-369-3p	CLIP-seq
MIRT762710	hsa-miR-374c	CLIP-seq
MIRT762711	hsa-miR-3919	CLIP-seq
MIRT762712	hsa-miR-3925-5p	CLIP-seq
MIRT762713	hsa-miR-3936	CLIP-seq
MIRT762714	hsa-miR-3973	CLIP-seq
MIRT762715	hsa-miR-4266	CLIP-seq
MIRT762716	hsa-miR-4271	CLIP-seq
MIRT762717	hsa-miR-4293	CLIP-seq
MIRT762718	hsa-miR-4311	CLIP-seq
MIRT762719	hsa-miR-4499	CLIP-seq
MIRT762720	hsa-miR-4525	CLIP-seq
MIRT762721	hsa-miR-4535	CLIP-seq
MIRT762722	hsa-miR-4665-5p	CLIP-seq
MIRT762723	hsa-miR-4666-3p	CLIP-seq
MIRT762724	hsa-miR-4677-5p	CLIP-seq
MIRT762725	hsa-miR-4694-5p	CLIP-seq
MIRT762726	hsa-miR-4723-5p	CLIP-seq
MIRT762727	hsa-miR-4725-3p	CLIP-seq
MIRT762728	hsa-miR-4731-3p	CLIP-seq
MIRT762729	hsa-miR-4752	CLIP-seq
MIRT762730	hsa-miR-4764-5p	CLIP-seq
MIRT762731	hsa-miR-4776-5p	CLIP-seq
MIRT762732	hsa-miR-4781-3p	CLIP-seq
MIRT762733	hsa-miR-4797-5p	CLIP-seq
MIRT762734	hsa-miR-4801	CLIP-seq
MIRT762735	hsa-miR-4803	CLIP-seq
MIRT762736	hsa-miR-513a-5p	CLIP-seq
MIRT762737	hsa-miR-518a-5p	CLIP-seq
MIRT762738	hsa-miR-527	CLIP-seq
MIRT762739	hsa-miR-544	CLIP-seq
MIRT762740	hsa-miR-548c-3p	CLIP-seq
MIRT762741	hsa-miR-578	CLIP-seq
MIRT762742	hsa-miR-587	CLIP-seq
MIRT762743	hsa-miR-596	CLIP-seq
MIRT762744	hsa-miR-609	CLIP-seq
MIRT762745	hsa-miR-625	CLIP-seq
MIRT762746	hsa-miR-635	CLIP-seq
MIRT762747	hsa-miR-641	CLIP-seq
MIRT762748	hsa-miR-655	CLIP-seq
MIRT762749	hsa-miR-711	CLIP-seq
MIRT762750	hsa-miR-885-3p	CLIP-seq
MIRT762751	hsa-miR-935	CLIP-seq
MIRT762752	hsa-miR-101	CLIP-seq
MIRT762753	hsa-miR-1202	CLIP-seq
MIRT762691	hsa-miR-1207-3p	CLIP-seq
MIRT762692	hsa-miR-1244	CLIP-seq
MIRT762754	hsa-miR-1250	CLIP-seq
MIRT762694	hsa-miR-1258	CLIP-seq
MIRT762695	hsa-miR-1275	CLIP-seq
MIRT762696	hsa-miR-1289	CLIP-seq
MIRT762697	hsa-miR-1324	CLIP-seq
MIRT762755	hsa-miR-181a	CLIP-seq
MIRT762756	hsa-miR-181b	CLIP-seq
MIRT762757	hsa-miR-181c	CLIP-seq
MIRT762758	hsa-miR-181d	CLIP-seq
MIRT762759	hsa-miR-2115	CLIP-seq
MIRT762698	hsa-miR-2116	CLIP-seq
MIRT762760	hsa-miR-214	CLIP-seq
MIRT762699	hsa-miR-22	CLIP-seq
MIRT762761	hsa-miR-224	CLIP-seq
MIRT762700	hsa-miR-27a	CLIP-seq
MIRT762701	hsa-miR-27b	CLIP-seq
MIRT762762	hsa-miR-3120-3p	CLIP-seq
MIRT762763	hsa-miR-3120-5p	CLIP-seq
MIRT762764	hsa-miR-3148	CLIP-seq
MIRT762702	hsa-miR-3152-3p	CLIP-seq
MIRT762765	hsa-miR-3155	CLIP-seq
MIRT762766	hsa-miR-3155b	CLIP-seq
MIRT762703	hsa-miR-3160-5p	CLIP-seq
MIRT762704	hsa-miR-3179	CLIP-seq
MIRT762705	hsa-miR-3189-3p	CLIP-seq
MIRT762767	hsa-miR-3194-5p	CLIP-seq
MIRT762706	hsa-miR-3617	CLIP-seq
MIRT762768	hsa-miR-3619-5p	CLIP-seq
MIRT762769	hsa-miR-3660	CLIP-seq
MIRT762770	hsa-miR-3667-5p	CLIP-seq
MIRT762771	hsa-miR-3688-3p	CLIP-seq
MIRT762708	hsa-miR-3691-5p	CLIP-seq
MIRT762709	hsa-miR-369-3p	CLIP-seq
MIRT762772	hsa-miR-374a	CLIP-seq
MIRT762773	hsa-miR-374b	CLIP-seq
MIRT762710	hsa-miR-374c	CLIP-seq
MIRT762774	hsa-miR-3915	CLIP-seq
MIRT762711	hsa-miR-3919	CLIP-seq
MIRT762712	hsa-miR-3925-5p	CLIP-seq
MIRT762775	hsa-miR-3928	CLIP-seq
MIRT762713	hsa-miR-3936	CLIP-seq
MIRT762776	hsa-miR-3972	CLIP-seq
MIRT762714	hsa-miR-3973	CLIP-seq
MIRT762777	hsa-miR-4262	CLIP-seq
MIRT762715	hsa-miR-4266	CLIP-seq
MIRT762717	hsa-miR-4293	CLIP-seq
MIRT762778	hsa-miR-4422	CLIP-seq
MIRT762719	hsa-miR-4499	CLIP-seq
MIRT762779	hsa-miR-4526	CLIP-seq
MIRT762721	hsa-miR-4535	CLIP-seq
MIRT762780	hsa-miR-4645-3p	CLIP-seq
MIRT762781	hsa-miR-4645-5p	CLIP-seq
MIRT762722	hsa-miR-4665-5p	CLIP-seq
MIRT762723	hsa-miR-4666-3p	CLIP-seq
MIRT762782	hsa-miR-4673	CLIP-seq
MIRT762724	hsa-miR-4677-5p	CLIP-seq
MIRT762783	hsa-miR-4687-3p	CLIP-seq
MIRT762784	hsa-miR-4690-5p	CLIP-seq
MIRT762725	hsa-miR-4694-5p	CLIP-seq
MIRT762785	hsa-miR-4719	CLIP-seq
MIRT762728	hsa-miR-4731-3p	CLIP-seq
MIRT762729	hsa-miR-4752	CLIP-seq
MIRT762730	hsa-miR-4764-5p	CLIP-seq
MIRT762731	hsa-miR-4776-5p	CLIP-seq
MIRT762732	hsa-miR-4781-3p	CLIP-seq
MIRT762786	hsa-miR-4793-5p	CLIP-seq
MIRT762733	hsa-miR-4797-5p	CLIP-seq
MIRT762734	hsa-miR-4801	CLIP-seq
MIRT762735	hsa-miR-4803	CLIP-seq
MIRT762787	hsa-miR-486-5p	CLIP-seq
MIRT762736	hsa-miR-513a-5p	CLIP-seq
MIRT762788	hsa-miR-516a-3p	CLIP-seq
MIRT762737	hsa-miR-518a-5p	CLIP-seq
MIRT762738	hsa-miR-527	CLIP-seq
MIRT762739	hsa-miR-544	CLIP-seq
MIRT762789	hsa-miR-550a	CLIP-seq
MIRT762741	hsa-miR-578	CLIP-seq
MIRT762742	hsa-miR-587	CLIP-seq
MIRT762743	hsa-miR-596	CLIP-seq
MIRT762744	hsa-miR-609	CLIP-seq
MIRT762790	hsa-miR-614	CLIP-seq
MIRT762791	hsa-miR-626	CLIP-seq
MIRT762746	hsa-miR-635	CLIP-seq
MIRT762747	hsa-miR-641	CLIP-seq
MIRT762748	hsa-miR-655	CLIP-seq
MIRT762792	hsa-miR-7	CLIP-seq
MIRT762749	hsa-miR-711	CLIP-seq
MIRT762793	hsa-miR-761	CLIP-seq
MIRT762750	hsa-miR-885-3p	CLIP-seq
MIRT762751	hsa-miR-935	CLIP-seq
MIRT762759	hsa-miR-2115	CLIP-seq
MIRT762706	hsa-miR-3617	CLIP-seq
MIRT762709	hsa-miR-369-3p	CLIP-seq
MIRT762772	hsa-miR-374a	CLIP-seq
MIRT762773	hsa-miR-374b	CLIP-seq
MIRT762728	hsa-miR-4731-3p	CLIP-seq
MIRT762734	hsa-miR-4801	CLIP-seq
MIRT762735	hsa-miR-4803	CLIP-seq
MIRT762788	hsa-miR-516a-3p	CLIP-seq
MIRT762742	hsa-miR-587	CLIP-seq
MIRT762747	hsa-miR-641	CLIP-seq
MIRT762752	hsa-miR-101	CLIP-seq
MIRT762753	hsa-miR-1202	CLIP-seq
MIRT762691	hsa-miR-1207-3p	CLIP-seq
MIRT762695	hsa-miR-1275	CLIP-seq
MIRT1924845	hsa-miR-1298	CLIP-seq
MIRT762697	hsa-miR-1324	CLIP-seq
MIRT762755	hsa-miR-181a	CLIP-seq
MIRT762756	hsa-miR-181b	CLIP-seq
MIRT762757	hsa-miR-181c	CLIP-seq
MIRT762758	hsa-miR-181d	CLIP-seq
MIRT762759	hsa-miR-2115	CLIP-seq
MIRT762698	hsa-miR-2116	CLIP-seq
MIRT762760	hsa-miR-214	CLIP-seq
MIRT1924846	hsa-miR-217	CLIP-seq
MIRT762761	hsa-miR-224	CLIP-seq
MIRT762700	hsa-miR-27a	CLIP-seq
MIRT762701	hsa-miR-27b	CLIP-seq
MIRT762762	hsa-miR-3120-3p	CLIP-seq
MIRT762763	hsa-miR-3120-5p	CLIP-seq
MIRT762765	hsa-miR-3155	CLIP-seq
MIRT762766	hsa-miR-3155b	CLIP-seq
MIRT762703	hsa-miR-3160-5p	CLIP-seq
MIRT1924847	hsa-miR-3163	CLIP-seq
MIRT1924848	hsa-miR-3170	CLIP-seq
MIRT762767	hsa-miR-3194-5p	CLIP-seq
MIRT1924849	hsa-miR-340	CLIP-seq
MIRT1924850	hsa-miR-342-5p	CLIP-seq
MIRT762706	hsa-miR-3617	CLIP-seq
MIRT762768	hsa-miR-3619-5p	CLIP-seq
MIRT762707	hsa-miR-3655	CLIP-seq
MIRT762769	hsa-miR-3660	CLIP-seq
MIRT762770	hsa-miR-3667-5p	CLIP-seq
MIRT762709	hsa-miR-369-3p	CLIP-seq
MIRT762772	hsa-miR-374a	CLIP-seq
MIRT762773	hsa-miR-374b	CLIP-seq
MIRT762710	hsa-miR-374c	CLIP-seq
MIRT762711	hsa-miR-3919	CLIP-seq
MIRT762712	hsa-miR-3925-5p	CLIP-seq
MIRT1924851	hsa-miR-3938	CLIP-seq
MIRT762776	hsa-miR-3972	CLIP-seq
MIRT1924852	hsa-miR-410	CLIP-seq
MIRT762777	hsa-miR-4262	CLIP-seq
MIRT762716	hsa-miR-4271	CLIP-seq
MIRT1924853	hsa-miR-4328	CLIP-seq
MIRT1924854	hsa-miR-4418	CLIP-seq
MIRT1924855	hsa-miR-4521	CLIP-seq
MIRT762720	hsa-miR-4525	CLIP-seq
MIRT762779	hsa-miR-4526	CLIP-seq
MIRT762780	hsa-miR-4645-3p	CLIP-seq
MIRT1924856	hsa-miR-4651	CLIP-seq
MIRT1924857	hsa-miR-4664-5p	CLIP-seq
MIRT762722	hsa-miR-4665-5p	CLIP-seq
MIRT762723	hsa-miR-4666-3p	CLIP-seq
MIRT762724	hsa-miR-4677-5p	CLIP-seq
MIRT762783	hsa-miR-4687-3p	CLIP-seq
MIRT762784	hsa-miR-4690-5p	CLIP-seq
MIRT762785	hsa-miR-4719	CLIP-seq
MIRT762726	hsa-miR-4723-5p	CLIP-seq
MIRT762727	hsa-miR-4725-3p	CLIP-seq
MIRT762728	hsa-miR-4731-3p	CLIP-seq
MIRT762786	hsa-miR-4793-5p	CLIP-seq
MIRT762733	hsa-miR-4797-5p	CLIP-seq
MIRT762734	hsa-miR-4801	CLIP-seq
MIRT762735	hsa-miR-4803	CLIP-seq
MIRT1924858	hsa-miR-509-3-5p	CLIP-seq
MIRT1924859	hsa-miR-509-5p	CLIP-seq
MIRT1924860	hsa-miR-511	CLIP-seq
MIRT762736	hsa-miR-513a-5p	CLIP-seq
MIRT762788	hsa-miR-516a-3p	CLIP-seq
MIRT762739	hsa-miR-544	CLIP-seq
MIRT1924861	hsa-miR-567	CLIP-seq
MIRT762741	hsa-miR-578	CLIP-seq
MIRT762742	hsa-miR-587	CLIP-seq
MIRT1924862	hsa-miR-608	CLIP-seq
MIRT762745	hsa-miR-625	CLIP-seq
MIRT762791	hsa-miR-626	CLIP-seq
MIRT762746	hsa-miR-635	CLIP-seq
MIRT762747	hsa-miR-641	CLIP-seq
MIRT762748	hsa-miR-655	CLIP-seq
MIRT762793	hsa-miR-761	CLIP-seq
MIRT762751	hsa-miR-935	CLIP-seq
MIRT762752	hsa-miR-101	CLIP-seq
MIRT762753	hsa-miR-1202	CLIP-seq
MIRT762691	hsa-miR-1207-3p	CLIP-seq
MIRT762693	hsa-miR-1253	CLIP-seq
MIRT762695	hsa-miR-1275	CLIP-seq
MIRT2166055	hsa-miR-129-3p	CLIP-seq
MIRT2166056	hsa-miR-1304	CLIP-seq
MIRT762697	hsa-miR-1324	CLIP-seq
MIRT762755	hsa-miR-181a	CLIP-seq
MIRT762756	hsa-miR-181b	CLIP-seq
MIRT762757	hsa-miR-181c	CLIP-seq
MIRT762758	hsa-miR-181d	CLIP-seq
MIRT2166057	hsa-miR-2113	CLIP-seq
MIRT762759	hsa-miR-2115	CLIP-seq
MIRT762698	hsa-miR-2116	CLIP-seq
MIRT762760	hsa-miR-214	CLIP-seq
MIRT762699	hsa-miR-22	CLIP-seq
MIRT762761	hsa-miR-224	CLIP-seq
MIRT2166058	hsa-miR-2276	CLIP-seq
MIRT762700	hsa-miR-27a	CLIP-seq
MIRT762701	hsa-miR-27b	CLIP-seq
MIRT2166059	hsa-miR-297	CLIP-seq
MIRT762762	hsa-miR-3120-3p	CLIP-seq
MIRT762763	hsa-miR-3120-5p	CLIP-seq
MIRT2166060	hsa-miR-3145-5p	CLIP-seq
MIRT762765	hsa-miR-3155	CLIP-seq
MIRT762766	hsa-miR-3155b	CLIP-seq
MIRT2166061	hsa-miR-3156-5p	CLIP-seq
MIRT762703	hsa-miR-3160-5p	CLIP-seq
MIRT762767	hsa-miR-3194-5p	CLIP-seq
MIRT762706	hsa-miR-3617	CLIP-seq
MIRT762768	hsa-miR-3619-5p	CLIP-seq
MIRT762707	hsa-miR-3655	CLIP-seq
MIRT762769	hsa-miR-3660	CLIP-seq
MIRT762709	hsa-miR-369-3p	CLIP-seq
MIRT762772	hsa-miR-374a	CLIP-seq
MIRT762773	hsa-miR-374b	CLIP-seq
MIRT762710	hsa-miR-374c	CLIP-seq
MIRT762711	hsa-miR-3919	CLIP-seq
MIRT2166062	hsa-miR-3924	CLIP-seq
MIRT762712	hsa-miR-3925-5p	CLIP-seq
MIRT762776	hsa-miR-3972	CLIP-seq
MIRT1924852	hsa-miR-410	CLIP-seq
MIRT762777	hsa-miR-4262	CLIP-seq
MIRT762716	hsa-miR-4271	CLIP-seq
MIRT2166063	hsa-miR-4276	CLIP-seq
MIRT762719	hsa-miR-4499	CLIP-seq
MIRT2166064	hsa-miR-4504	CLIP-seq
MIRT1924855	hsa-miR-4521	CLIP-seq
MIRT762720	hsa-miR-4525	CLIP-seq
MIRT762779	hsa-miR-4526	CLIP-seq
MIRT2166065	hsa-miR-4527	CLIP-seq
MIRT762780	hsa-miR-4645-3p	CLIP-seq
MIRT2166066	hsa-miR-4654	CLIP-seq
MIRT762722	hsa-miR-4665-5p	CLIP-seq
MIRT762723	hsa-miR-4666-3p	CLIP-seq
MIRT762724	hsa-miR-4677-5p	CLIP-seq
MIRT762783	hsa-miR-4687-3p	CLIP-seq
MIRT762785	hsa-miR-4719	CLIP-seq
MIRT762726	hsa-miR-4723-5p	CLIP-seq
MIRT762727	hsa-miR-4725-3p	CLIP-seq
MIRT762728	hsa-miR-4731-3p	CLIP-seq
MIRT2166067	hsa-miR-4769-5p	CLIP-seq
MIRT2166068	hsa-miR-4772-3p	CLIP-seq
MIRT762733	hsa-miR-4797-5p	CLIP-seq
MIRT762734	hsa-miR-4801	CLIP-seq
MIRT762735	hsa-miR-4803	CLIP-seq
MIRT2166069	hsa-miR-508-5p	CLIP-seq
MIRT1924860	hsa-miR-511	CLIP-seq
MIRT762736	hsa-miR-513a-5p	CLIP-seq
MIRT762788	hsa-miR-516a-3p	CLIP-seq
MIRT2166070	hsa-miR-526b	CLIP-seq
MIRT2166071	hsa-miR-542-3p	CLIP-seq
MIRT762739	hsa-miR-544	CLIP-seq
MIRT762740	hsa-miR-548c-3p	CLIP-seq
MIRT1924861	hsa-miR-567	CLIP-seq
MIRT762741	hsa-miR-578	CLIP-seq
MIRT762742	hsa-miR-587	CLIP-seq
MIRT762745	hsa-miR-625	CLIP-seq
MIRT762791	hsa-miR-626	CLIP-seq
MIRT762746	hsa-miR-635	CLIP-seq
MIRT762747	hsa-miR-641	CLIP-seq
MIRT762748	hsa-miR-655	CLIP-seq
MIRT2166072	hsa-miR-758	CLIP-seq
MIRT762793	hsa-miR-761	CLIP-seq
MIRT762750	hsa-miR-885-3p	CLIP-seq
MIRT762751	hsa-miR-935	CLIP-seq
MIRT2166073	hsa-miR-938	CLIP-seq
MIRT762752	hsa-miR-101	CLIP-seq
MIRT762692	hsa-miR-1244	CLIP-seq
MIRT762755	hsa-miR-181a	CLIP-seq
MIRT762756	hsa-miR-181b	CLIP-seq
MIRT762757	hsa-miR-181c	CLIP-seq
MIRT762758	hsa-miR-181d	CLIP-seq
MIRT762759	hsa-miR-2115	CLIP-seq
MIRT762698	hsa-miR-2116	CLIP-seq
MIRT762769	hsa-miR-3660	CLIP-seq
MIRT762708	hsa-miR-3691-5p	CLIP-seq
MIRT762710	hsa-miR-374c	CLIP-seq
MIRT762714	hsa-miR-3973	CLIP-seq
MIRT762777	hsa-miR-4262	CLIP-seq
MIRT762779	hsa-miR-4526	CLIP-seq
MIRT762780	hsa-miR-4645-3p	CLIP-seq
MIRT762723	hsa-miR-4666-3p	CLIP-seq
MIRT762724	hsa-miR-4677-5p	CLIP-seq
MIRT762783	hsa-miR-4687-3p	CLIP-seq
MIRT762729	hsa-miR-4752	CLIP-seq
MIRT762786	hsa-miR-4793-5p	CLIP-seq
MIRT762788	hsa-miR-516a-3p	CLIP-seq
MIRT762737	hsa-miR-518a-5p	CLIP-seq
MIRT762738	hsa-miR-527	CLIP-seq
MIRT762740	hsa-miR-548c-3p	CLIP-seq
MIRT762742	hsa-miR-587	CLIP-seq
MIRT762748	hsa-miR-655	CLIP-seq
MIRT1924861	hsa-miR-567	CLIP-seq
MIRT762733	hsa-miR-4797-5p	CLIP-seq
MIRT762733	hsa-miR-4797-5p	CLIP-seq
MIRT1924861	hsa-miR-567	CLIP-seq
MIRT762752	hsa-miR-101	CLIP-seq
MIRT762691	hsa-miR-1207-3p	CLIP-seq
MIRT2468584	hsa-miR-1269	CLIP-seq
MIRT2468585	hsa-miR-1269b	CLIP-seq
MIRT2468586	hsa-miR-127-5p	CLIP-seq
MIRT2468587	hsa-miR-1288	CLIP-seq
MIRT2166055	hsa-miR-129-3p	CLIP-seq
MIRT2468588	hsa-miR-147	CLIP-seq
MIRT2166057	hsa-miR-2113	CLIP-seq
MIRT762759	hsa-miR-2115	CLIP-seq
MIRT762698	hsa-miR-2116	CLIP-seq
MIRT762760	hsa-miR-214	CLIP-seq
MIRT762761	hsa-miR-224	CLIP-seq
MIRT2166058	hsa-miR-2276	CLIP-seq
MIRT762700	hsa-miR-27a	CLIP-seq
MIRT762701	hsa-miR-27b	CLIP-seq
MIRT2166059	hsa-miR-297	CLIP-seq
MIRT762762	hsa-miR-3120-3p	CLIP-seq
MIRT2468589	hsa-miR-3138	CLIP-seq
MIRT2166060	hsa-miR-3145-5p	CLIP-seq
MIRT762702	hsa-miR-3152-3p	CLIP-seq
MIRT2166061	hsa-miR-3156-5p	CLIP-seq
MIRT762703	hsa-miR-3160-5p	CLIP-seq
MIRT1924847	hsa-miR-3163	CLIP-seq
MIRT762704	hsa-miR-3179	CLIP-seq
MIRT2468590	hsa-miR-3185	CLIP-seq
MIRT2468591	hsa-miR-3189-5p	CLIP-seq
MIRT1924849	hsa-miR-340	CLIP-seq
MIRT762706	hsa-miR-3617	CLIP-seq
MIRT762768	hsa-miR-3619-5p	CLIP-seq
MIRT2468592	hsa-miR-3663-5p	CLIP-seq
MIRT762709	hsa-miR-369-3p	CLIP-seq
MIRT762772	hsa-miR-374a	CLIP-seq
MIRT762773	hsa-miR-374b	CLIP-seq
MIRT762710	hsa-miR-374c	CLIP-seq
MIRT2468593	hsa-miR-3911	CLIP-seq
MIRT762711	hsa-miR-3919	CLIP-seq
MIRT2166062	hsa-miR-3924	CLIP-seq
MIRT762712	hsa-miR-3925-5p	CLIP-seq
MIRT762713	hsa-miR-3936	CLIP-seq
MIRT1924852	hsa-miR-410	CLIP-seq
MIRT2166063	hsa-miR-4276	CLIP-seq
MIRT762717	hsa-miR-4293	CLIP-seq
MIRT2468594	hsa-miR-4477a	CLIP-seq
MIRT2166064	hsa-miR-4504	CLIP-seq
MIRT2468595	hsa-miR-4515	CLIP-seq
MIRT2468596	hsa-miR-4517	CLIP-seq
MIRT1924855	hsa-miR-4521	CLIP-seq
MIRT2468597	hsa-miR-4522	CLIP-seq
MIRT2166065	hsa-miR-4527	CLIP-seq
MIRT762780	hsa-miR-4645-3p	CLIP-seq
MIRT2166066	hsa-miR-4654	CLIP-seq
MIRT762723	hsa-miR-4666-3p	CLIP-seq
MIRT762724	hsa-miR-4677-5p	CLIP-seq
MIRT762725	hsa-miR-4694-5p	CLIP-seq
MIRT762785	hsa-miR-4719	CLIP-seq
MIRT762728	hsa-miR-4731-3p	CLIP-seq
MIRT2468598	hsa-miR-4740-5p	CLIP-seq
MIRT2166067	hsa-miR-4769-5p	CLIP-seq
MIRT2166068	hsa-miR-4772-3p	CLIP-seq
MIRT762733	hsa-miR-4797-5p	CLIP-seq
MIRT2468599	hsa-miR-4800-5p	CLIP-seq
MIRT762734	hsa-miR-4801	CLIP-seq
MIRT762735	hsa-miR-4803	CLIP-seq
MIRT2166069	hsa-miR-508-5p	CLIP-seq
MIRT762736	hsa-miR-513a-5p	CLIP-seq
MIRT762788	hsa-miR-516a-3p	CLIP-seq
MIRT2166071	hsa-miR-542-3p	CLIP-seq
MIRT762739	hsa-miR-544	CLIP-seq
MIRT762740	hsa-miR-548c-3p	CLIP-seq
MIRT1924861	hsa-miR-567	CLIP-seq
MIRT762742	hsa-miR-587	CLIP-seq
MIRT762743	hsa-miR-596	CLIP-seq
MIRT2468600	hsa-miR-599	CLIP-seq
MIRT762744	hsa-miR-609	CLIP-seq
MIRT762747	hsa-miR-641	CLIP-seq
MIRT2468601	hsa-miR-644	CLIP-seq
MIRT762748	hsa-miR-655	CLIP-seq
MIRT2166072	hsa-miR-758	CLIP-seq
MIRT762793	hsa-miR-761	CLIP-seq
MIRT2166073	hsa-miR-938	CLIP-seq
MIRT762752	hsa-miR-101	CLIP-seq
MIRT762691	hsa-miR-1207-3p	CLIP-seq
MIRT2468584	hsa-miR-1269	CLIP-seq
MIRT2468585	hsa-miR-1269b	CLIP-seq
MIRT2468586	hsa-miR-127-5p	CLIP-seq
MIRT2468587	hsa-miR-1288	CLIP-seq
MIRT2166055	hsa-miR-129-3p	CLIP-seq
MIRT2468588	hsa-miR-147	CLIP-seq
MIRT2166057	hsa-miR-2113	CLIP-seq
MIRT762759	hsa-miR-2115	CLIP-seq
MIRT762698	hsa-miR-2116	CLIP-seq
MIRT762760	hsa-miR-214	CLIP-seq
MIRT762761	hsa-miR-224	CLIP-seq
MIRT2166058	hsa-miR-2276	CLIP-seq
MIRT762700	hsa-miR-27a	CLIP-seq
MIRT762701	hsa-miR-27b	CLIP-seq
MIRT2166059	hsa-miR-297	CLIP-seq
MIRT762762	hsa-miR-3120-3p	CLIP-seq
MIRT2468589	hsa-miR-3138	CLIP-seq
MIRT2166060	hsa-miR-3145-5p	CLIP-seq
MIRT762702	hsa-miR-3152-3p	CLIP-seq
MIRT2166061	hsa-miR-3156-5p	CLIP-seq
MIRT762703	hsa-miR-3160-5p	CLIP-seq
MIRT1924847	hsa-miR-3163	CLIP-seq
MIRT762704	hsa-miR-3179	CLIP-seq
MIRT2468590	hsa-miR-3185	CLIP-seq
MIRT2468591	hsa-miR-3189-5p	CLIP-seq
MIRT1924849	hsa-miR-340	CLIP-seq
MIRT762706	hsa-miR-3617	CLIP-seq
MIRT762768	hsa-miR-3619-5p	CLIP-seq
MIRT2468592	hsa-miR-3663-5p	CLIP-seq
MIRT762708	hsa-miR-3691-5p	CLIP-seq
MIRT762709	hsa-miR-369-3p	CLIP-seq
MIRT762772	hsa-miR-374a	CLIP-seq
MIRT762773	hsa-miR-374b	CLIP-seq
MIRT762710	hsa-miR-374c	CLIP-seq
MIRT2468593	hsa-miR-3911	CLIP-seq
MIRT762711	hsa-miR-3919	CLIP-seq
MIRT2166062	hsa-miR-3924	CLIP-seq
MIRT762712	hsa-miR-3925-5p	CLIP-seq
MIRT762713	hsa-miR-3936	CLIP-seq
MIRT1924852	hsa-miR-410	CLIP-seq
MIRT2166063	hsa-miR-4276	CLIP-seq
MIRT762717	hsa-miR-4293	CLIP-seq
MIRT2468594	hsa-miR-4477a	CLIP-seq
MIRT2166064	hsa-miR-4504	CLIP-seq
MIRT2468595	hsa-miR-4515	CLIP-seq
MIRT2468596	hsa-miR-4517	CLIP-seq
MIRT1924855	hsa-miR-4521	CLIP-seq
MIRT2468597	hsa-miR-4522	CLIP-seq
MIRT2166065	hsa-miR-4527	CLIP-seq
MIRT762780	hsa-miR-4645-3p	CLIP-seq
MIRT2166066	hsa-miR-4654	CLIP-seq
MIRT762723	hsa-miR-4666-3p	CLIP-seq
MIRT762724	hsa-miR-4677-5p	CLIP-seq
MIRT762725	hsa-miR-4694-5p	CLIP-seq
MIRT762785	hsa-miR-4719	CLIP-seq
MIRT762728	hsa-miR-4731-3p	CLIP-seq
MIRT2468598	hsa-miR-4740-5p	CLIP-seq
MIRT762729	hsa-miR-4752	CLIP-seq
MIRT762730	hsa-miR-4764-5p	CLIP-seq
MIRT2166067	hsa-miR-4769-5p	CLIP-seq
MIRT2166068	hsa-miR-4772-3p	CLIP-seq
MIRT762732	hsa-miR-4781-3p	CLIP-seq
MIRT762733	hsa-miR-4797-5p	CLIP-seq
MIRT2468599	hsa-miR-4800-5p	CLIP-seq
MIRT762734	hsa-miR-4801	CLIP-seq
MIRT762735	hsa-miR-4803	CLIP-seq
MIRT2166069	hsa-miR-508-5p	CLIP-seq
MIRT762736	hsa-miR-513a-5p	CLIP-seq
MIRT762788	hsa-miR-516a-3p	CLIP-seq
MIRT2166071	hsa-miR-542-3p	CLIP-seq
MIRT762739	hsa-miR-544	CLIP-seq
MIRT762740	hsa-miR-548c-3p	CLIP-seq
MIRT1924861	hsa-miR-567	CLIP-seq
MIRT762742	hsa-miR-587	CLIP-seq
MIRT762743	hsa-miR-596	CLIP-seq
MIRT2468600	hsa-miR-599	CLIP-seq
MIRT762744	hsa-miR-609	CLIP-seq
MIRT762747	hsa-miR-641	CLIP-seq
MIRT2468601	hsa-miR-644	CLIP-seq
MIRT762748	hsa-miR-655	CLIP-seq
MIRT2166072	hsa-miR-758	CLIP-seq
MIRT762793	hsa-miR-761	CLIP-seq
MIRT2166073	hsa-miR-938	CLIP-seq

Show/Hide all (1)

Transcription factor	Regulation	Reference
SREBF1	Activation	10777536

Show/Hide all (38)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0003824	Function	Catalytic activity	IEA
GO:0003878	Function	ATP citrate synthase activity	IBA
GO:0003878	Function	ATP citrate synthase activity	IDA	1371749, 9116495, 10653665, 19286649
GO:0003878	Function	ATP citrate synthase activity	IEA
GO:0003878	Function	ATP citrate synthase activity	TAS	23932781
GO:0005515	Function	Protein binding	IPI	23932781
GO:0005524	Function	ATP binding	IEA
GO:0005524	Function	ATP binding	TAS	1371749
GO:0005576	Component	Extracellular region	TAS
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA	9116495
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006085	Process	Acetyl-CoA biosynthetic process	IBA
GO:0006085	Process	Acetyl-CoA biosynthetic process	IDA	1371749
GO:0006085	Process	Acetyl-CoA biosynthetic process	IEA
GO:0006085	Process	Acetyl-CoA biosynthetic process	IMP	39881208
GO:0006101	Process	Citrate metabolic process	IDA	1371749
GO:0006101	Process	Citrate metabolic process	IEA
GO:0006107	Process	Oxaloacetate metabolic process	IDA	1371749
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006633	Process	Fatty acid biosynthetic process	IBA
GO:0006633	Process	Fatty acid biosynthetic process	IDA	10653665, 19286649
GO:0006695	Process	Cholesterol biosynthetic process	TAS	1371749
GO:0008610	Process	Lipid biosynthetic process	IDA	23932781
GO:0015936	Process	Coenzyme A metabolic process	TAS	1371749
GO:0016020	Component	Membrane	HDA	19946888
GO:0016740	Function	Transferase activity	IEA
GO:0035578	Component	Azurophil granule lumen	TAS
GO:0036064	Component	Ciliary basal body	IDA
GO:0046872	Function	Metal ion binding	IEA
GO:0046912	Function	Acyltransferase activity, acyl groups converted into alkyl on transfer	IEA
GO:0070062	Component	Extracellular exosome	HDA	19056867, 20458337, 23533145
GO:0110076	Process	Negative regulation of ferroptosis	IMP	39881208
GO:1904813	Component	Ficolin-1-rich granule lumen	TAS

MIM	HGNC	e!Ensembl
108728	115	ENSG00000131473

P53396

Protein name

ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (ACL) (Citrate cleavage enzyme)

Protein function

Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate in multiple biochemical reactions in protein, carbohydrate and lipid metabolism. {ECO:0000269|PubMed:10653665, ECO:0000269|PubMed:1371749,

PDB

3MWD , 3MWE , 3PFF , 5TDE , 5TDF , 5TDM , 5TDZ , 5TE1 , 5TEQ , 5TES , 5TET , 6HXH , 6HXK , 6HXL , 6HXM , 6O0H , 6POE , 6POF , 6QFB , 6UI9 , 6UIA , 6UUW , 6UUZ , 6UV5 , 6Z2H , 7LIW , 7LJ9 , 7LLA , 7RIG , 7RKZ , 7RMP , 8G1E , 8G1F , 8G5C , 8G5D

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF16114	Citrate_bind	244 → 421	ATP citrate lyase citrate-binding	Domain
PF02629	CoA_binding	494 → 600	CoA binding domain	Domain
PF00549	Ligase_CoA	660 → 785	CoA-ligase	Domain
PF00285	Citrate_synt	883 → 1086	Citrate synthase, C-terminal domain	Domain

Sequence

MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPD
QLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFY
VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEI
LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPP
PFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNE
LANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRA
IRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALG
HRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQDSVP
SPRSLQGKSTTLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQK
FYWGHKEILIPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEG
IPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYV
SRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIG
GTEEYKICRGIKEGRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALK
EAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASF
MTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADH
GPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFV
NKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPN
LILNVDGLIGVAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLK
QGLYRHPWDDISYVLPEHMSM

Sequence length

1101

Interactions

View interactions

	KEGG		Reactome
	Citrate cycle (TCA cycle) Metabolic pathways		ChREBP activates metabolic gene expression Neutrophil degranulation Fatty acyl-CoA biosynthesis

Show/Hide Unknown Diseases (8)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Familial cancer of breast	Likely benign	rs148168367	RCV005907705
Gastric cancer	Likely benign	rs148168367	RCV005907708
Lung cancer	Likely benign	rs148168367	RCV005907712
Malignant tumor of esophagus	Likely benign	rs148168367	RCV005907706
Melanoma	Likely benign	rs148168367	RCV005907711
Ovarian serous cystadenocarcinoma	Likely benign	rs148168367	RCV005907709
Pancreatic adenocarcinoma	Likely benign	rs148168367	RCV005907707
Thyroid cancer, nonmedullary, 1	Likely benign	rs148168367	RCV005907710

Show/Hide Text Mining Associations (53)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Arthritis Infectious	Stimulate	37414769
Behcet Syndrome	Stimulate	30050389
Breast Neoplasms	Associate	26928812, 28443474, 37899460
Breast Neoplasms	Stimulate	36562384
Carcinogenesis	Associate	35449157, 38009671
Carcinoma Hepatocellular	Associate	25735330, 29271183, 30176945, 34311471, 35227773, 35449157
Carcinoma Non Small Cell Lung	Associate	25227797, 25962060
Carcinoma Ovarian Epithelial	Associate	22266777
Carcinoma Pancreatic Ductal	Stimulate	34505339
Cardiovascular Diseases	Associate	30865797, 32231389
Cardiovascular Diseases	Inhibit	39202419
Cholangiocarcinoma	Associate	39399493
Colorectal Neoplasms	Stimulate	24132143
Colorectal Neoplasms	Associate	25890184, 33484818, 35177584
Corneal Endothelial Cell Loss	Inhibit	37414769
Death	Associate	25890184
Diabetes Mellitus Type 2	Stimulate	26367490
Diabetes Mellitus Type 2	Associate	39202419
Fatty Liver	Stimulate	37414769
Fatty Liver	Associate	37620891
Gallbladder Neoplasms	Associate	37747441
Gerstmann Syndrome	Associate	25227797, 25735330, 25826294
Hypoxia	Associate	26452058, 35227773
Inflammation	Associate	25619261, 37414769, 37620891
Leukemia	Associate	31077215
Leukemia Myeloid Acute	Associate	31077215
Liver Diseases	Associate	32054087
Lung Neoplasms	Associate	25227797, 38069382
Melanoma	Associate	37801083
Metabolic Diseases	Associate	37620891
Multiple Organ Failure	Associate	37414769
Myelodysplastic Syndromes	Associate	33462268
Neoplasm Metastasis	Associate	37122003
Neoplasm Metastasis	Stimulate	38009671
Neoplasms	Associate	16226706, 22266777, 23807225, 24980815, 25890184, 25962060, 26452058, 26477310, 28230778, 31077215, 31828117, 32849657, 33484818, 34573442, 36269753 View all (4 more)
Neoplasms	Stimulate	36064336, 37414769
Non alcoholic Fatty Liver Disease	Associate	23931760, 32054087
Oligodendroglioma	Associate	25277207
Oncogene Addiction	Stimulate	36494469
Osteoarthritis	Associate	29929979
Osteoarthritis Knee	Associate	29929979
Ovarian Neoplasms	Stimulate	22266777
Pancreatic Neoplasms	Associate	34505339
Peritonitis	Stimulate	38009671
Prostatic Neoplasms	Associate	24980815, 27248322
Prostatic Neoplasms Castration Resistant	Associate	27248322
Prostatitis	Associate	27248322
Protein S Deficiency	Inhibit	25277207
Sepsis	Associate	37414769
Sexual Dysfunction Physiological	Associate	37747441
Squamous Cell Carcinoma of Head and Neck	Associate	32597160
Stomach Neoplasms	Associate	36064336
Stomach Neoplasms	Stimulate	38009671

ACLY (ATP citrate lyase)