Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
4697
Gene name Gene Name - the full gene name approved by the HGNC.
Cytochrome c oxidase associated subunit FA4
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
COXFA4
Synonyms (NCBI Gene) Gene synonyms aliases
CI-9k, CI-MLRQ, MC4DN21, MISTR1, MLRQ, MRCAF1, NDUFA4
Chromosome Chromosome number
7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7p21.3
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT021524 hsa-miR-145-5p Reporter assay;Microarray 21351259
MIRT025792 hsa-miR-7-5p Microarray 19073608
MIRT031645 hsa-miR-16-5p Sequencing 20371350
MIRT045020 hsa-miR-186-5p CLASH 23622248
MIRT037742 hsa-miR-147b CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 19822128, 31536960, 32814053
GO:0005739 Component Mitochondrion HTP 34800366
GO:0005739 Component Mitochondrion IDA 16729965
GO:0005739 Component Mitochondrion IEA
GO:0005743 Component Mitochondrial inner membrane IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
603833 7687 ENSG00000189043
Protein
UniProt ID O00483
Protein name Cytochrome c oxidase subunit NDUFA4 (Complex I-MLRQ) (CI-MLRQ) (NADH-ubiquinone oxidoreductase MLRQ subunit)
Protein function Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiqu
PDB 5Z62
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF06522 B12D 11 78 NADH-ubiquinone reductase complex 1 MLRQ subunit Family
Sequence
Sequence length 81
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Oxidative phosphorylation
Metabolic pathways
Thermogenesis
Retrograde endocannabinoid signaling
Non-alcoholic fatty liver disease
Alzheimer disease
Parkinson disease
Amyotrophic lateral sclerosis
Huntington disease
Prion disease
Pathways of neurodegeneration - multiple diseases
Chemical carcinogenesis - reactive oxygen species
Diabetic cardiomyopathy
  TP53 Regulates Metabolic Genes
Respiratory electron transport
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