NBL1 (NBL1, DAN family BMP antagonist)

Gene

• Entrez ID: 4681
• Gene name: NBL1, DAN family BMP antagonist
• Gene symbol: NBL1
• Synonyms (NCBI Gene): D1S1733E, DAN, DAND1, NB, NO3
• Chromosome: 1
• Chromosome location: 1p36.13
• Summary: This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins ar

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT023164	hsa-miR-124-3p	Microarray	18668037
MIRT024064	hsa-miR-1-3p	Microarray	18668037
MIRT025945	hsa-miR-7-5p	Microarray	19073608
MIRT472444	hsa-miR-4779	PAR-CLIP	23592263
MIRT472443	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT472442	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT472441	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT472439	hsa-miR-4270	PAR-CLIP	23592263
MIRT472440	hsa-miR-4441	PAR-CLIP	23592263
MIRT472438	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT472437	hsa-miR-6891-5p	PAR-CLIP	23592263
MIRT472444	hsa-miR-4779	PAR-CLIP	23592263
MIRT472443	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT472442	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT472441	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT472439	hsa-miR-4270	PAR-CLIP	23592263
MIRT472440	hsa-miR-4441	PAR-CLIP	23592263
MIRT472438	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT472437	hsa-miR-6891-5p	PAR-CLIP	23592263
MIRT1174802	hsa-miR-1275	CLIP-seq
MIRT1174803	hsa-miR-323b-5p	CLIP-seq
MIRT1174804	hsa-miR-4646-3p	CLIP-seq
MIRT1174805	hsa-miR-4665-5p	CLIP-seq
MIRT1174806	hsa-miR-4667-3p	CLIP-seq
MIRT1174807	hsa-miR-635	CLIP-seq
MIRT2050554	hsa-miR-103a	CLIP-seq
MIRT2050555	hsa-miR-107	CLIP-seq
MIRT2050556	hsa-miR-1179	CLIP-seq
MIRT2050557	hsa-miR-1297	CLIP-seq
MIRT2050558	hsa-miR-1471	CLIP-seq
MIRT2050559	hsa-miR-26a	CLIP-seq
MIRT2050560	hsa-miR-26b	CLIP-seq
MIRT2050561	hsa-miR-361-3p	CLIP-seq
MIRT2050562	hsa-miR-4286	CLIP-seq
MIRT2050563	hsa-miR-4310	CLIP-seq
MIRT2050564	hsa-miR-4465	CLIP-seq
MIRT2438862	hsa-miR-1238	CLIP-seq
MIRT2438863	hsa-miR-1251	CLIP-seq
MIRT2438864	hsa-miR-1285	CLIP-seq
MIRT2438865	hsa-miR-1296	CLIP-seq
MIRT2438866	hsa-miR-1324	CLIP-seq
MIRT2050558	hsa-miR-1471	CLIP-seq
MIRT2438867	hsa-miR-1587	CLIP-seq
MIRT2438868	hsa-miR-1915	CLIP-seq
MIRT2438869	hsa-miR-1972	CLIP-seq
MIRT2438870	hsa-miR-214	CLIP-seq
MIRT2438871	hsa-miR-2278	CLIP-seq
MIRT2438872	hsa-miR-2682	CLIP-seq
MIRT2438873	hsa-miR-296-5p	CLIP-seq
MIRT2438874	hsa-miR-3130-3p	CLIP-seq
MIRT2438875	hsa-miR-3135	CLIP-seq
MIRT2438876	hsa-miR-3143	CLIP-seq
MIRT2438877	hsa-miR-3160-5p	CLIP-seq
MIRT2438878	hsa-miR-3166	CLIP-seq
MIRT2438879	hsa-miR-3184	CLIP-seq
MIRT2438880	hsa-miR-3187-5p	CLIP-seq
MIRT2438881	hsa-miR-34a	CLIP-seq
MIRT2438882	hsa-miR-34c-5p	CLIP-seq
MIRT2050561	hsa-miR-361-3p	CLIP-seq
MIRT2438883	hsa-miR-3619-5p	CLIP-seq
MIRT2438884	hsa-miR-3620	CLIP-seq
MIRT2438885	hsa-miR-3649	CLIP-seq
MIRT2438886	hsa-miR-3675-3p	CLIP-seq
MIRT2438887	hsa-miR-3690	CLIP-seq
MIRT2438888	hsa-miR-3909	CLIP-seq
MIRT2438889	hsa-miR-3940-3p	CLIP-seq
MIRT2438890	hsa-miR-423-5p	CLIP-seq
MIRT2438891	hsa-miR-4254	CLIP-seq
MIRT2438892	hsa-miR-4258	CLIP-seq
MIRT2438893	hsa-miR-4291	CLIP-seq
MIRT2438894	hsa-miR-4292	CLIP-seq
MIRT2438895	hsa-miR-4326	CLIP-seq
MIRT2438896	hsa-miR-4417	CLIP-seq
MIRT2438897	hsa-miR-4459	CLIP-seq
MIRT2438898	hsa-miR-4468	CLIP-seq
MIRT2438899	hsa-miR-4492	CLIP-seq
MIRT2438900	hsa-miR-4498	CLIP-seq
MIRT2438901	hsa-miR-449a	CLIP-seq
MIRT2438902	hsa-miR-449b	CLIP-seq
MIRT2438903	hsa-miR-449c	CLIP-seq
MIRT2438904	hsa-miR-4512	CLIP-seq
MIRT2438905	hsa-miR-4640-5p	CLIP-seq
MIRT2438906	hsa-miR-4645-5p	CLIP-seq
MIRT2438907	hsa-miR-4653-3p	CLIP-seq
MIRT2438908	hsa-miR-4656	CLIP-seq
MIRT2438909	hsa-miR-4659a-3p	CLIP-seq
MIRT2438910	hsa-miR-4659b-3p	CLIP-seq
MIRT2438911	hsa-miR-4673	CLIP-seq
MIRT2438912	hsa-miR-4675	CLIP-seq
MIRT2438913	hsa-miR-4691-3p	CLIP-seq
MIRT2438914	hsa-miR-4717-5p	CLIP-seq
MIRT2438915	hsa-miR-4722-5p	CLIP-seq
MIRT2438916	hsa-miR-4726-5p	CLIP-seq
MIRT2438917	hsa-miR-4731-5p	CLIP-seq
MIRT2438918	hsa-miR-4732-3p	CLIP-seq
MIRT2438919	hsa-miR-4741	CLIP-seq
MIRT2438920	hsa-miR-4755-3p	CLIP-seq
MIRT2438921	hsa-miR-4786-3p	CLIP-seq
MIRT2438922	hsa-miR-4793-3p	CLIP-seq
MIRT2438923	hsa-miR-512-3p	CLIP-seq
MIRT2438924	hsa-miR-543	CLIP-seq
MIRT2438925	hsa-miR-612	CLIP-seq
MIRT2438926	hsa-miR-665	CLIP-seq
MIRT2438927	hsa-miR-761	CLIP-seq
MIRT2438928	hsa-miR-762	CLIP-seq
MIRT2438929	hsa-miR-885-3p	CLIP-seq
MIRT2438930	hsa-miR-891a	CLIP-seq
MIRT2438931	hsa-miR-922	CLIP-seq
MIRT2438932	hsa-miR-943	CLIP-seq
MIRT2442402	hsa-miR-1255a	CLIP-seq
MIRT2442403	hsa-miR-1255b	CLIP-seq
MIRT2442404	hsa-miR-1470	CLIP-seq
MIRT2050558	hsa-miR-1471	CLIP-seq
MIRT2442405	hsa-miR-150	CLIP-seq
MIRT2438867	hsa-miR-1587	CLIP-seq
MIRT2438869	hsa-miR-1972	CLIP-seq
MIRT2438872	hsa-miR-2682	CLIP-seq
MIRT2442406	hsa-miR-3126-5p	CLIP-seq
MIRT2438881	hsa-miR-34a	CLIP-seq
MIRT2438882	hsa-miR-34c-5p	CLIP-seq
MIRT2442407	hsa-miR-3692	CLIP-seq
MIRT2438896	hsa-miR-4417	CLIP-seq
MIRT2438897	hsa-miR-4459	CLIP-seq
MIRT2438899	hsa-miR-4492	CLIP-seq
MIRT2438900	hsa-miR-4498	CLIP-seq
MIRT2438901	hsa-miR-449a	CLIP-seq
MIRT2438902	hsa-miR-449b	CLIP-seq
MIRT2438903	hsa-miR-449c	CLIP-seq
MIRT2442408	hsa-miR-4525	CLIP-seq
MIRT2438905	hsa-miR-4640-5p	CLIP-seq
MIRT2438906	hsa-miR-4645-5p	CLIP-seq
MIRT2438908	hsa-miR-4656	CLIP-seq
MIRT2438911	hsa-miR-4673	CLIP-seq
MIRT2438912	hsa-miR-4675	CLIP-seq
MIRT2438914	hsa-miR-4717-5p	CLIP-seq
MIRT2438915	hsa-miR-4722-5p	CLIP-seq
MIRT2438916	hsa-miR-4726-5p	CLIP-seq
MIRT2438919	hsa-miR-4741	CLIP-seq
MIRT2438920	hsa-miR-4755-3p	CLIP-seq
MIRT2438924	hsa-miR-543	CLIP-seq
MIRT2438926	hsa-miR-665	CLIP-seq
MIRT2438928	hsa-miR-762	CLIP-seq
MIRT2438929	hsa-miR-885-3p	CLIP-seq
MIRT2578327	hsa-miR-1193	CLIP-seq
MIRT2578328	hsa-miR-1227	CLIP-seq
MIRT2578329	hsa-miR-1270	CLIP-seq
MIRT2578330	hsa-miR-1273f	CLIP-seq
MIRT2578331	hsa-miR-128	CLIP-seq
MIRT2442404	hsa-miR-1470	CLIP-seq
MIRT2050558	hsa-miR-1471	CLIP-seq
MIRT2578332	hsa-miR-148a	CLIP-seq
MIRT2578333	hsa-miR-148b	CLIP-seq
MIRT2442405	hsa-miR-150	CLIP-seq
MIRT2578334	hsa-miR-152	CLIP-seq
MIRT2438868	hsa-miR-1915	CLIP-seq
MIRT2438869	hsa-miR-1972	CLIP-seq
MIRT2438870	hsa-miR-214	CLIP-seq
MIRT2438872	hsa-miR-2682	CLIP-seq
MIRT2442406	hsa-miR-3126-5p	CLIP-seq
MIRT2578335	hsa-miR-3127-5p	CLIP-seq
MIRT2438874	hsa-miR-3130-3p	CLIP-seq
MIRT2438876	hsa-miR-3143	CLIP-seq
MIRT2438877	hsa-miR-3160-5p	CLIP-seq
MIRT2578336	hsa-miR-3180	CLIP-seq
MIRT2578337	hsa-miR-3180-3p	CLIP-seq
MIRT2578338	hsa-miR-3196	CLIP-seq
MIRT2438881	hsa-miR-34a	CLIP-seq
MIRT2438882	hsa-miR-34c-5p	CLIP-seq
MIRT2050561	hsa-miR-361-3p	CLIP-seq
MIRT2438883	hsa-miR-3619-5p	CLIP-seq
MIRT2438885	hsa-miR-3649	CLIP-seq
MIRT2438889	hsa-miR-3940-3p	CLIP-seq
MIRT2578339	hsa-miR-4252	CLIP-seq
MIRT2438891	hsa-miR-4254	CLIP-seq
MIRT2578340	hsa-miR-4260	CLIP-seq
MIRT2578341	hsa-miR-4263	CLIP-seq
MIRT2578342	hsa-miR-4276	CLIP-seq
MIRT2438893	hsa-miR-4291	CLIP-seq
MIRT2438894	hsa-miR-4292	CLIP-seq
MIRT2578343	hsa-miR-4308	CLIP-seq
MIRT2578344	hsa-miR-4314	CLIP-seq
MIRT2578345	hsa-miR-432	CLIP-seq
MIRT2438897	hsa-miR-4459	CLIP-seq
MIRT2438901	hsa-miR-449a	CLIP-seq
MIRT2438902	hsa-miR-449b	CLIP-seq
MIRT2438903	hsa-miR-449c	CLIP-seq
MIRT2442408	hsa-miR-4525	CLIP-seq
MIRT2438905	hsa-miR-4640-5p	CLIP-seq
MIRT2438906	hsa-miR-4645-5p	CLIP-seq
MIRT1174806	hsa-miR-4667-3p	CLIP-seq
MIRT2578346	hsa-miR-4667-5p	CLIP-seq
MIRT2438911	hsa-miR-4673	CLIP-seq
MIRT2578347	hsa-miR-4683	CLIP-seq
MIRT2578348	hsa-miR-4700-5p	CLIP-seq
MIRT2578349	hsa-miR-4706	CLIP-seq
MIRT2438914	hsa-miR-4717-5p	CLIP-seq
MIRT2438915	hsa-miR-4722-5p	CLIP-seq
MIRT2438916	hsa-miR-4726-5p	CLIP-seq
MIRT2578350	hsa-miR-4747-5p	CLIP-seq
MIRT2578351	hsa-miR-4749-5p	CLIP-seq
MIRT2438920	hsa-miR-4755-3p	CLIP-seq
MIRT2578352	hsa-miR-4757-5p	CLIP-seq
MIRT2438922	hsa-miR-4793-3p	CLIP-seq
MIRT2578353	hsa-miR-4795-5p	CLIP-seq
MIRT2578354	hsa-miR-486-3p	CLIP-seq
MIRT2438924	hsa-miR-543	CLIP-seq
MIRT2578355	hsa-miR-576-5p	CLIP-seq
MIRT2578356	hsa-miR-620	CLIP-seq
MIRT1174807	hsa-miR-635	CLIP-seq
MIRT2578357	hsa-miR-637	CLIP-seq
MIRT2438926	hsa-miR-665	CLIP-seq
MIRT2578358	hsa-miR-670	CLIP-seq
MIRT2578359	hsa-miR-744	CLIP-seq
MIRT2438927	hsa-miR-761	CLIP-seq
MIRT2438929	hsa-miR-885-3p	CLIP-seq
MIRT2438931	hsa-miR-922	CLIP-seq
MIRT2685857	hsa-miR-106a	CLIP-seq
MIRT2685858	hsa-miR-106b	CLIP-seq
MIRT2578327	hsa-miR-1193	CLIP-seq
MIRT2578328	hsa-miR-1227	CLIP-seq
MIRT2578329	hsa-miR-1270	CLIP-seq
MIRT2578330	hsa-miR-1273f	CLIP-seq
MIRT1174802	hsa-miR-1275	CLIP-seq
MIRT2578331	hsa-miR-128	CLIP-seq
MIRT2685859	hsa-miR-1301	CLIP-seq
MIRT2442404	hsa-miR-1470	CLIP-seq
MIRT2050558	hsa-miR-1471	CLIP-seq
MIRT2578332	hsa-miR-148a	CLIP-seq
MIRT2578333	hsa-miR-148b	CLIP-seq
MIRT2442405	hsa-miR-150	CLIP-seq
MIRT2578334	hsa-miR-152	CLIP-seq
MIRT2438867	hsa-miR-1587	CLIP-seq
MIRT2685860	hsa-miR-17	CLIP-seq
MIRT2438868	hsa-miR-1915	CLIP-seq
MIRT2438869	hsa-miR-1972	CLIP-seq
MIRT2685861	hsa-miR-20a	CLIP-seq
MIRT2685862	hsa-miR-20b	CLIP-seq
MIRT2438870	hsa-miR-214	CLIP-seq
MIRT2438872	hsa-miR-2682	CLIP-seq
MIRT2442406	hsa-miR-3126-5p	CLIP-seq
MIRT2578335	hsa-miR-3127-5p	CLIP-seq
MIRT2438874	hsa-miR-3130-3p	CLIP-seq
MIRT2438876	hsa-miR-3143	CLIP-seq
MIRT2438877	hsa-miR-3160-5p	CLIP-seq
MIRT2578336	hsa-miR-3180	CLIP-seq
MIRT2578337	hsa-miR-3180-3p	CLIP-seq
MIRT2685863	hsa-miR-3192	CLIP-seq
MIRT2578338	hsa-miR-3196	CLIP-seq
MIRT1174803	hsa-miR-323b-5p	CLIP-seq
MIRT2685864	hsa-miR-342-5p	CLIP-seq
MIRT2438881	hsa-miR-34a	CLIP-seq
MIRT2438882	hsa-miR-34c-5p	CLIP-seq
MIRT2685865	hsa-miR-3609	CLIP-seq
MIRT2050561	hsa-miR-361-3p	CLIP-seq
MIRT2438883	hsa-miR-3619-5p	CLIP-seq
MIRT2438885	hsa-miR-3649	CLIP-seq
MIRT2438889	hsa-miR-3940-3p	CLIP-seq
MIRT2578339	hsa-miR-4252	CLIP-seq
MIRT2438891	hsa-miR-4254	CLIP-seq
MIRT2578340	hsa-miR-4260	CLIP-seq
MIRT2578341	hsa-miR-4263	CLIP-seq
MIRT2578342	hsa-miR-4276	CLIP-seq
MIRT2438893	hsa-miR-4291	CLIP-seq
MIRT2438894	hsa-miR-4292	CLIP-seq
MIRT2578343	hsa-miR-4308	CLIP-seq
MIRT2578344	hsa-miR-4314	CLIP-seq
MIRT2578345	hsa-miR-432	CLIP-seq
MIRT2438896	hsa-miR-4417	CLIP-seq
MIRT2438897	hsa-miR-4459	CLIP-seq
MIRT2438899	hsa-miR-4492	CLIP-seq
MIRT2438900	hsa-miR-4498	CLIP-seq
MIRT2438901	hsa-miR-449a	CLIP-seq
MIRT2438902	hsa-miR-449b	CLIP-seq
MIRT2438903	hsa-miR-449c	CLIP-seq
MIRT2442408	hsa-miR-4525	CLIP-seq
MIRT2438905	hsa-miR-4640-5p	CLIP-seq
MIRT2438906	hsa-miR-4645-5p	CLIP-seq
MIRT2685866	hsa-miR-4651	CLIP-seq
MIRT2438908	hsa-miR-4656	CLIP-seq
MIRT2685867	hsa-miR-4664-5p	CLIP-seq
MIRT1174805	hsa-miR-4665-5p	CLIP-seq
MIRT2578346	hsa-miR-4667-5p	CLIP-seq
MIRT2438911	hsa-miR-4673	CLIP-seq
MIRT2438912	hsa-miR-4675	CLIP-seq
MIRT2578347	hsa-miR-4683	CLIP-seq
MIRT2438913	hsa-miR-4691-3p	CLIP-seq
MIRT2578348	hsa-miR-4700-5p	CLIP-seq
MIRT2578349	hsa-miR-4706	CLIP-seq
MIRT2438914	hsa-miR-4717-5p	CLIP-seq
MIRT2438915	hsa-miR-4722-5p	CLIP-seq
MIRT2438916	hsa-miR-4726-5p	CLIP-seq
MIRT2438919	hsa-miR-4741	CLIP-seq
MIRT2578350	hsa-miR-4747-5p	CLIP-seq
MIRT2578351	hsa-miR-4749-5p	CLIP-seq
MIRT2438920	hsa-miR-4755-3p	CLIP-seq
MIRT2438922	hsa-miR-4793-3p	CLIP-seq
MIRT2578353	hsa-miR-4795-5p	CLIP-seq
MIRT2685868	hsa-miR-4796-3p	CLIP-seq
MIRT2578354	hsa-miR-486-3p	CLIP-seq
MIRT2685869	hsa-miR-519a	CLIP-seq
MIRT2685870	hsa-miR-519d	CLIP-seq
MIRT2438924	hsa-miR-543	CLIP-seq
MIRT2685871	hsa-miR-548ah	CLIP-seq
MIRT2578355	hsa-miR-576-5p	CLIP-seq
MIRT2685872	hsa-miR-608	CLIP-seq
MIRT2578356	hsa-miR-620	CLIP-seq
MIRT1174807	hsa-miR-635	CLIP-seq
MIRT2578357	hsa-miR-637	CLIP-seq
MIRT2438926	hsa-miR-665	CLIP-seq
MIRT2578358	hsa-miR-670	CLIP-seq
MIRT2578359	hsa-miR-744	CLIP-seq
MIRT2438927	hsa-miR-761	CLIP-seq
MIRT2438928	hsa-miR-762	CLIP-seq
MIRT2438929	hsa-miR-885-3p	CLIP-seq
MIRT2438931	hsa-miR-922	CLIP-seq
MIRT2685873	hsa-miR-93	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 32296183, 32814053
GO:0005576	Component	Extracellular region	IEA
GO:0005615	Component	Extracellular space	IBA
GO:0005615	Component	Extracellular space	IC	23063586
GO:0005615	Component	Extracellular space	IDA	11594460
GO:0007165	Process	Signal transduction	IEA
GO:0007399	Process	Nervous system development	IEA
GO:0007399	Process	Nervous system development	ISS
GO:0016015	Function	Morphogen activity	IEA
GO:0016015	Function	Morphogen activity	ISS
GO:0030182	Process	Neuron differentiation	IEA
GO:0030514	Process	Negative regulation of BMP signaling pathway	IDA	23063586
GO:0030514	Process	Negative regulation of BMP signaling pathway	IEA
GO:0030514	Process	Negative regulation of BMP signaling pathway	IEA
GO:0030514	Process	Negative regulation of BMP signaling pathway	IMP	25561725
GO:0035581	Process	Sequestering of extracellular ligand from receptor	IEA
GO:0035582	Process	Sequestering of BMP in extracellular matrix	IEA
GO:0035582	Process	Sequestering of BMP in extracellular matrix	ISS
GO:0036122	Function	BMP binding	IBA
GO:0036122	Function	BMP binding	IEA
GO:0036122	Function	BMP binding	ISS
GO:0038098	Process	Sequestering of BMP from receptor via BMP binding	IBA
GO:0038098	Process	Sequestering of BMP from receptor via BMP binding	IDA	23063586
GO:0042802	Function	Identical protein binding	IMP	23063586
GO:0045666	Process	Positive regulation of neuron differentiation	IEA
GO:0045666	Process	Positive regulation of neuron differentiation	ISS
GO:0048018	Function	Receptor ligand activity	IBA
GO:0048263	Process	Determination of dorsal identity	IEA
GO:0048263	Process	Determination of dorsal identity	ISS
GO:0048812	Process	Neuron projection morphogenesis	IEA
GO:0048812	Process	Neuron projection morphogenesis	ISS
GO:0090027	Process	Negative regulation of monocyte chemotaxis	IEA
GO:0090027	Process	Negative regulation of monocyte chemotaxis	ISS

Other IDs

• MIM: 600613
• HGNC: 7650
• e!Ensembl: ENSG00000158747

Interactions View interactions

Pathways

KEGG:

TGF-beta signaling pathway