Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
4664
Gene name Gene Name - the full gene name approved by the HGNC.
NGFI-A binding protein 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
NAB1
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2q32.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT018222 hsa-miR-335-5p Microarray 18185580
MIRT023860 hsa-miR-1-3p Microarray 18668037
MIRT024468 hsa-miR-215-5p Microarray 19074876
MIRT026655 hsa-miR-192-5p Microarray 19074876
MIRT051328 hsa-miR-15a-5p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001958 Process Endochondral ossification IEA
GO:0003712 Function Transcription coregulator activity IBA 21873635
GO:0005634 Component Nucleus IBA 21873635
GO:0005634 Component Nucleus NAS 8668170
GO:0006355 Process Regulation of transcription, DNA-templated IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
600800 7626 ENSG00000138386
Protein
UniProt ID Q13506
Protein name NGFI-A-binding protein 1 (EGR-1-binding protein 1) (Transcriptional regulatory protein p54)
Protein function Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2.
PDB 2YUF
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04904 NCD1 5 83 NAB conserved region 1 (NCD1) Domain
PF04905 NCD2 190 318 NAB conserved region 2 (NCD2) Family
PF04902 Nab1 322 486 Conserved region in Nab1 Family
Tissue specificity TISSUE SPECIFICITY: Isoform Short is found in myeloid leukemia cell line KG-1.
Sequence
Sequence length 487
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    NGF-stimulated transcription
EGR2 and SOX10-mediated initiation of Schwann cell myelination
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Biliary Cholangitis Biliary Cholangitis GWAS
Rheumatoid arthritis Rheumatoid arthritis GWAS
Hypertension Hypertension GWAS
Multiple Sclerosis Multiple Sclerosis GWAS
Associations from Text Mining
Disease Name Relationship Type References
Narcolepsy Associate 37188663
Neoplasms Associate 23025254
Sjogren's Syndrome Associate 35896530