Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	4601
Gene name Gene Name - the full gene name approved by the HGNC.	MAX interactor 1, dimerization protein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MXI1
Synonyms (NCBI Gene) Gene synonyms aliases	MAD2, MXD2, MXI, bHLHc11
Chromosome Chromosome number	10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	10q25.2
Summary Summary of gene provided in NCBI Entrez Gene.	Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regu

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SNP ID	Visualize variation	Clinical significance	Consequence
rs137852603	A>C	Pathogenic	Missense variant, coding sequence variant
rs137852604	C>T	Pathogenic	Missense variant, coding sequence variant
rs387906417	T>C	Pathogenic	Splice donor variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT017857	hsa-miR-335-5p	Microarray	18185580
MIRT001748	hsa-miR-375	Other	15806104
MIRT020453	hsa-miR-106b-5p	Microarray	17242205
MIRT024480	hsa-miR-215-5p	Microarray	19074876
MIRT026461	hsa-miR-192-5p	Microarray	19074876
MIRT029559	hsa-miR-26b-5p	Microarray	19088304
MIRT047907	hsa-miR-30c-5p	CLASH	23622248
MIRT020453	hsa-miR-106b-5p	CLASH	23622248
MIRT040089	hsa-miR-615-3p	CLASH	23622248
MIRT039065	hsa-miR-769-3p	CLASH	23622248
MIRT053042	hsa-miR-24-3p	Luciferase reporter assay, qRT-PCR, Western blot	23254855
MIRT053042	hsa-miR-24-3p	Luciferase reporter assay, qRT-PCR, Western blot	23254855
MIRT053043	hsa-miR-27a-5p	Luciferase reporter assay, qRT-PCR, Western blot	23254855
MIRT053043	hsa-miR-27a-5p	Luciferase reporter assay, qRT-PCR, Western blot	23254855
MIRT053043	hsa-miR-27a-5p	Luciferase reporter assay, qRT-PCR, Western blot	23254855
MIRT053043	hsa-miR-27a-5p	Luciferase reporter assay, qRT-PCR, Western blot	23254855
MIRT438018	hsa-miR-155-5p	Luciferase reporter assay, qRT-PCR, Western blot	24376632
MIRT438018	hsa-miR-155-5p	Luciferase reporter assay, qRT-PCR, Western blot	24376632
MIRT438018	hsa-miR-155-5p	Luciferase reporter assay, qRT-PCR, Western blot	24376632
MIRT438018	hsa-miR-155-5p	Luciferase reporter assay, qRT-PCR, Western blot	24376632
MIRT438018	hsa-miR-155-5p	Luciferase reporter assay, qRT-PCR, Western blot	24376632
MIRT438018	hsa-miR-155-5p	Luciferase reporter assay, qRT-PCR, Western blot	24376632
MIRT438018	hsa-miR-155-5p	Luciferase reporter assay, qRT-PCR, Western blot	24376632
MIRT438018	hsa-miR-155-5p	Luciferase reporter assay, qRT-PCR, Western blot	24376632
MIRT642035	hsa-miR-590-3p	HITS-CLIP	23824327
MIRT642034	hsa-miR-4735-5p	HITS-CLIP	23824327
MIRT642033	hsa-miR-4775	HITS-CLIP	23824327
MIRT443502	hsa-miR-302f	PAR-CLIP	23446348
MIRT443498	hsa-miR-4768-3p	PAR-CLIP	23446348
MIRT443497	hsa-miR-219b-3p	PAR-CLIP	23446348
MIRT522413	hsa-miR-377-5p	PAR-CLIP	23446348
MIRT522412	hsa-miR-6086	PAR-CLIP	23446348
MIRT443495	hsa-miR-4722-5p	PAR-CLIP	23446348
MIRT522411	hsa-miR-6499-3p	PAR-CLIP	23446348
MIRT522410	hsa-miR-3689d	PAR-CLIP	23446348
MIRT522409	hsa-miR-6851-5p	PAR-CLIP	23446348
MIRT472715	hsa-miR-6880-5p	PAR-CLIP	23446348
MIRT472714	hsa-miR-7847-3p	PAR-CLIP	23446348
MIRT522408	hsa-miR-455-3p	PAR-CLIP	23446348
MIRT443494	hsa-miR-1273e	PAR-CLIP	23446348
MIRT522407	hsa-miR-6516-5p	PAR-CLIP	23446348
MIRT446664	hsa-miR-548g-3p	PAR-CLIP	22291592
MIRT446663	hsa-miR-216b-3p	PAR-CLIP	22291592
MIRT446662	hsa-miR-342-3p	PAR-CLIP	22291592
MIRT446661	hsa-miR-676-5p	PAR-CLIP	22291592
MIRT446660	hsa-miR-6715b-3p	PAR-CLIP	22291592
MIRT443502	hsa-miR-302f	PAR-CLIP	23592263
MIRT443500	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT443501	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT443499	hsa-miR-940	PAR-CLIP	23592263
MIRT443498	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT443497	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT443496	hsa-miR-1827	PAR-CLIP	23592263
MIRT443495	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT472715	hsa-miR-6880-5p	PAR-CLIP	23592263
MIRT472714	hsa-miR-7847-3p	PAR-CLIP	23592263
MIRT443494	hsa-miR-1273e	PAR-CLIP	23592263
MIRT446664	hsa-miR-548g-3p	PAR-CLIP	22100165
MIRT446663	hsa-miR-216b-3p	PAR-CLIP	22100165
MIRT446662	hsa-miR-342-3p	PAR-CLIP	22100165
MIRT446661	hsa-miR-676-5p	PAR-CLIP	22100165
MIRT446660	hsa-miR-6715b-3p	PAR-CLIP	22100165
MIRT446664	hsa-miR-548g-3p	PAR-CLIP	22100165
MIRT446663	hsa-miR-216b-3p	PAR-CLIP	22100165
MIRT446662	hsa-miR-342-3p	PAR-CLIP	22100165
MIRT446661	hsa-miR-676-5p	PAR-CLIP	22100165
MIRT446660	hsa-miR-6715b-3p	PAR-CLIP	22100165
MIRT443502	hsa-miR-302f	PAR-CLIP	22100165
MIRT443500	hsa-miR-6808-5p	PAR-CLIP	22100165
MIRT443501	hsa-miR-6893-5p	PAR-CLIP	22100165
MIRT443499	hsa-miR-940	PAR-CLIP	22100165
MIRT443498	hsa-miR-4768-3p	PAR-CLIP	22100165
MIRT443497	hsa-miR-219b-3p	PAR-CLIP	22100165
MIRT443496	hsa-miR-1827	PAR-CLIP	22100165
MIRT443495	hsa-miR-4722-5p	PAR-CLIP	22100165
MIRT443494	hsa-miR-1273e	PAR-CLIP	22100165
MIRT020453	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT440170	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT020453	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT727129	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT727128	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT727127	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT727126	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT440170	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT522410	hsa-miR-3689d	PAR-CLIP	27292025
MIRT522413	hsa-miR-377-5p	PAR-CLIP	27292025
MIRT522408	hsa-miR-455-3p	PAR-CLIP	27292025
MIRT522412	hsa-miR-6086	PAR-CLIP	27292025
MIRT522411	hsa-miR-6499-3p	PAR-CLIP	27292025
MIRT522407	hsa-miR-6516-5p	PAR-CLIP	27292025
MIRT522409	hsa-miR-6851-5p	PAR-CLIP	27292025
MIRT472715	hsa-miR-6880-5p	PAR-CLIP	27292025
MIRT472714	hsa-miR-7847-3p	PAR-CLIP	27292025
MIRT020453	hsa-miR-106b-5p	qRT-PCR	33773548
MIRT642035	hsa-miR-590-3p	HITS-CLIP	23824327
MIRT642034	hsa-miR-4735-5p	HITS-CLIP	23824327
MIRT642033	hsa-miR-4775	HITS-CLIP	23824327
MIRT443502	hsa-miR-302f	PAR-CLIP	23446348
MIRT443498	hsa-miR-4768-3p	PAR-CLIP	23446348
MIRT443497	hsa-miR-219b-3p	PAR-CLIP	23446348
MIRT522413	hsa-miR-377-5p	PAR-CLIP	23446348
MIRT522412	hsa-miR-6086	PAR-CLIP	23446348
MIRT443495	hsa-miR-4722-5p	PAR-CLIP	23446348
MIRT522411	hsa-miR-6499-3p	PAR-CLIP	23446348
MIRT522410	hsa-miR-3689d	PAR-CLIP	23446348
MIRT522409	hsa-miR-6851-5p	PAR-CLIP	23446348
MIRT472715	hsa-miR-6880-5p	PAR-CLIP	23446348
MIRT472714	hsa-miR-7847-3p	PAR-CLIP	23446348
MIRT522408	hsa-miR-455-3p	PAR-CLIP	23446348
MIRT443494	hsa-miR-1273e	PAR-CLIP	23446348
MIRT522407	hsa-miR-6516-5p	PAR-CLIP	23446348
MIRT446664	hsa-miR-548g-3p	PAR-CLIP	22291592
MIRT446663	hsa-miR-216b-3p	PAR-CLIP	22291592
MIRT446662	hsa-miR-342-3p	PAR-CLIP	22291592
MIRT446661	hsa-miR-676-5p	PAR-CLIP	22291592
MIRT446660	hsa-miR-6715b-3p	PAR-CLIP	22291592
MIRT443502	hsa-miR-302f	PAR-CLIP	23592263
MIRT443500	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT443501	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT443499	hsa-miR-940	PAR-CLIP	23592263
MIRT443498	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT443497	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT443496	hsa-miR-1827	PAR-CLIP	23592263
MIRT443495	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT472715	hsa-miR-6880-5p	PAR-CLIP	23592263
MIRT472714	hsa-miR-7847-3p	PAR-CLIP	23592263
MIRT443494	hsa-miR-1273e	PAR-CLIP	23592263
MIRT446664	hsa-miR-548g-3p	PAR-CLIP	22100165
MIRT446663	hsa-miR-216b-3p	PAR-CLIP	22100165
MIRT446662	hsa-miR-342-3p	PAR-CLIP	22100165
MIRT446661	hsa-miR-676-5p	PAR-CLIP	22100165
MIRT446660	hsa-miR-6715b-3p	PAR-CLIP	22100165
MIRT446664	hsa-miR-548g-3p	PAR-CLIP	22100165
MIRT446663	hsa-miR-216b-3p	PAR-CLIP	22100165
MIRT446662	hsa-miR-342-3p	PAR-CLIP	22100165
MIRT446661	hsa-miR-676-5p	PAR-CLIP	22100165
MIRT446660	hsa-miR-6715b-3p	PAR-CLIP	22100165
MIRT443502	hsa-miR-302f	PAR-CLIP	22100165
MIRT443500	hsa-miR-6808-5p	PAR-CLIP	22100165
MIRT443501	hsa-miR-6893-5p	PAR-CLIP	22100165
MIRT443499	hsa-miR-940	PAR-CLIP	22100165
MIRT443498	hsa-miR-4768-3p	PAR-CLIP	22100165
MIRT443497	hsa-miR-219b-3p	PAR-CLIP	22100165
MIRT443496	hsa-miR-1827	PAR-CLIP	22100165
MIRT443495	hsa-miR-4722-5p	PAR-CLIP	22100165
MIRT443494	hsa-miR-1273e	PAR-CLIP	22100165
MIRT1167059	hsa-miR-128	CLIP-seq
MIRT1167060	hsa-miR-1294	CLIP-seq
MIRT1167061	hsa-miR-1297	CLIP-seq
MIRT1167062	hsa-miR-2355-5p	CLIP-seq
MIRT1167063	hsa-miR-26a	CLIP-seq
MIRT1167064	hsa-miR-26b	CLIP-seq
MIRT1167065	hsa-miR-3121-3p	CLIP-seq
MIRT1167066	hsa-miR-3199	CLIP-seq
MIRT1167067	hsa-miR-320a	CLIP-seq
MIRT1167068	hsa-miR-320b	CLIP-seq
MIRT1167069	hsa-miR-320c	CLIP-seq
MIRT1167070	hsa-miR-320d	CLIP-seq
MIRT1167071	hsa-miR-3618	CLIP-seq
MIRT1167072	hsa-miR-3679-3p	CLIP-seq
MIRT1167073	hsa-miR-3915	CLIP-seq
MIRT1167074	hsa-miR-3928	CLIP-seq
MIRT1167075	hsa-miR-3974	CLIP-seq
MIRT1167076	hsa-miR-4316	CLIP-seq
MIRT1167077	hsa-miR-4429	CLIP-seq
MIRT1167078	hsa-miR-4446-5p	CLIP-seq
MIRT1167079	hsa-miR-4465	CLIP-seq
MIRT1167080	hsa-miR-4648	CLIP-seq
MIRT1167081	hsa-miR-4677-3p	CLIP-seq
MIRT1167082	hsa-miR-4711-3p	CLIP-seq
MIRT1167083	hsa-miR-4725-5p	CLIP-seq
MIRT1167084	hsa-miR-504	CLIP-seq
MIRT1167085	hsa-miR-555	CLIP-seq
MIRT1167086	hsa-miR-648	CLIP-seq
MIRT1167087	hsa-miR-934	CLIP-seq
MIRT1167059	hsa-miR-128	CLIP-seq
MIRT1167060	hsa-miR-1294	CLIP-seq
MIRT1167088	hsa-miR-185	CLIP-seq
MIRT1167089	hsa-miR-214	CLIP-seq
MIRT1167090	hsa-miR-2392	CLIP-seq
MIRT1167066	hsa-miR-3199	CLIP-seq
MIRT1167091	hsa-miR-3619-5p	CLIP-seq
MIRT1167073	hsa-miR-3915	CLIP-seq
MIRT1167074	hsa-miR-3928	CLIP-seq
MIRT1167092	hsa-miR-4306	CLIP-seq
MIRT1167076	hsa-miR-4316	CLIP-seq
MIRT1167093	hsa-miR-4436b-3p	CLIP-seq
MIRT1167094	hsa-miR-4493	CLIP-seq
MIRT1167095	hsa-miR-4528	CLIP-seq
MIRT1167096	hsa-miR-4534	CLIP-seq
MIRT1167097	hsa-miR-4539	CLIP-seq
MIRT1167098	hsa-miR-4644	CLIP-seq
MIRT1167080	hsa-miR-4648	CLIP-seq
MIRT1167081	hsa-miR-4677-3p	CLIP-seq
MIRT1167099	hsa-miR-4753-5p	CLIP-seq
MIRT1167100	hsa-miR-495	CLIP-seq
MIRT1167101	hsa-miR-580	CLIP-seq
MIRT1167086	hsa-miR-648	CLIP-seq
MIRT1167102	hsa-miR-761	CLIP-seq
MIRT1167061	hsa-miR-1297	CLIP-seq
MIRT1167063	hsa-miR-26a	CLIP-seq
MIRT1167064	hsa-miR-26b	CLIP-seq
MIRT2277181	hsa-miR-433	CLIP-seq
MIRT2277182	hsa-miR-4438	CLIP-seq
MIRT1167079	hsa-miR-4465	CLIP-seq
MIRT2277183	hsa-miR-4769-3p	CLIP-seq
MIRT2277184	hsa-miR-544	CLIP-seq
MIRT2277185	hsa-miR-548c-3p	CLIP-seq
MIRT2277186	hsa-miR-583	CLIP-seq
MIRT2391208	hsa-miR-1915	CLIP-seq
MIRT2391209	hsa-miR-2113	CLIP-seq
MIRT2391210	hsa-miR-3202	CLIP-seq
MIRT2391211	hsa-miR-4747-5p	CLIP-seq
MIRT1167100	hsa-miR-495	CLIP-seq
MIRT2391212	hsa-miR-570	CLIP-seq
MIRT2454642	hsa-miR-24	CLIP-seq
MIRT2454643	hsa-miR-3136-3p	CLIP-seq
MIRT2454644	hsa-miR-4284	CLIP-seq
MIRT2454645	hsa-miR-4474-3p	CLIP-seq
MIRT1167094	hsa-miR-4493	CLIP-seq
MIRT2277185	hsa-miR-548c-3p	CLIP-seq
MIRT2575987	hsa-miR-1245b-5p	CLIP-seq
MIRT2575988	hsa-miR-1269	CLIP-seq
MIRT2575989	hsa-miR-1269b	CLIP-seq
MIRT2575990	hsa-miR-1276	CLIP-seq
MIRT2575991	hsa-miR-1288	CLIP-seq
MIRT1167061	hsa-miR-1297	CLIP-seq
MIRT2575992	hsa-miR-1298	CLIP-seq
MIRT1167088	hsa-miR-185	CLIP-seq
MIRT2391208	hsa-miR-1915	CLIP-seq
MIRT2575993	hsa-miR-2052	CLIP-seq
MIRT1167089	hsa-miR-214	CLIP-seq
MIRT1167090	hsa-miR-2392	CLIP-seq
MIRT1167063	hsa-miR-26a	CLIP-seq
MIRT1167064	hsa-miR-26b	CLIP-seq
MIRT2575994	hsa-miR-29a	CLIP-seq
MIRT2575995	hsa-miR-29b	CLIP-seq
MIRT2575996	hsa-miR-29c	CLIP-seq
MIRT2575997	hsa-miR-3142	CLIP-seq
MIRT2575998	hsa-miR-3166	CLIP-seq
MIRT2575999	hsa-miR-328	CLIP-seq
MIRT1167091	hsa-miR-3619-5p	CLIP-seq
MIRT2576000	hsa-miR-3647-3p	CLIP-seq
MIRT2576001	hsa-miR-3655	CLIP-seq
MIRT2576002	hsa-miR-374c	CLIP-seq
MIRT2576003	hsa-miR-3929	CLIP-seq
MIRT2576004	hsa-miR-3942-5p	CLIP-seq
MIRT1167092	hsa-miR-4306	CLIP-seq
MIRT2576005	hsa-miR-4311	CLIP-seq
MIRT2576006	hsa-miR-4312	CLIP-seq
MIRT2576007	hsa-miR-4419b	CLIP-seq
MIRT1167093	hsa-miR-4436b-3p	CLIP-seq
MIRT1167079	hsa-miR-4465	CLIP-seq
MIRT2576008	hsa-miR-4478	CLIP-seq
MIRT2576009	hsa-miR-4515	CLIP-seq
MIRT1167095	hsa-miR-4528	CLIP-seq
MIRT1167096	hsa-miR-4534	CLIP-seq
MIRT2576010	hsa-miR-4633-3p	CLIP-seq
MIRT1167098	hsa-miR-4644	CLIP-seq
MIRT2576011	hsa-miR-4668-3p	CLIP-seq
MIRT2576012	hsa-miR-4682	CLIP-seq
MIRT2576013	hsa-miR-4703-5p	CLIP-seq
MIRT2576014	hsa-miR-4717-3p	CLIP-seq
MIRT1167083	hsa-miR-4725-5p	CLIP-seq
MIRT2576015	hsa-miR-4726-3p	CLIP-seq
MIRT2576016	hsa-miR-4740-5p	CLIP-seq
MIRT2576017	hsa-miR-4802-3p	CLIP-seq
MIRT2576018	hsa-miR-485-5p	CLIP-seq
MIRT1167084	hsa-miR-504	CLIP-seq
MIRT2576019	hsa-miR-511	CLIP-seq
MIRT2576020	hsa-miR-545	CLIP-seq
MIRT2576021	hsa-miR-578	CLIP-seq
MIRT2277186	hsa-miR-583	CLIP-seq
MIRT2576022	hsa-miR-633	CLIP-seq
MIRT2576023	hsa-miR-655	CLIP-seq
MIRT2576024	hsa-miR-663b	CLIP-seq
MIRT1167102	hsa-miR-761	CLIP-seq
MIRT2576025	hsa-miR-802	CLIP-seq
MIRT2576026	hsa-miR-885-5p	CLIP-seq
MIRT2685584	hsa-miR-106a	CLIP-seq
MIRT2685585	hsa-miR-106b	CLIP-seq
MIRT2575987	hsa-miR-1245b-5p	CLIP-seq
MIRT2575988	hsa-miR-1269	CLIP-seq
MIRT2575989	hsa-miR-1269b	CLIP-seq
MIRT2575990	hsa-miR-1276	CLIP-seq
MIRT1167059	hsa-miR-128	CLIP-seq
MIRT2575991	hsa-miR-1288	CLIP-seq
MIRT1167061	hsa-miR-1297	CLIP-seq
MIRT2575992	hsa-miR-1298	CLIP-seq
MIRT2685586	hsa-miR-17	CLIP-seq
MIRT2391208	hsa-miR-1915	CLIP-seq
MIRT2575993	hsa-miR-2052	CLIP-seq
MIRT2685587	hsa-miR-20a	CLIP-seq
MIRT2685588	hsa-miR-20b	CLIP-seq
MIRT1167089	hsa-miR-214	CLIP-seq
MIRT1167090	hsa-miR-2392	CLIP-seq
MIRT1167063	hsa-miR-26a	CLIP-seq
MIRT1167064	hsa-miR-26b	CLIP-seq
MIRT2575994	hsa-miR-29a	CLIP-seq
MIRT2575995	hsa-miR-29b	CLIP-seq
MIRT2575996	hsa-miR-29c	CLIP-seq
MIRT2575997	hsa-miR-3142	CLIP-seq
MIRT2575998	hsa-miR-3166	CLIP-seq
MIRT1167066	hsa-miR-3199	CLIP-seq
MIRT2575999	hsa-miR-328	CLIP-seq
MIRT1167091	hsa-miR-3619-5p	CLIP-seq
MIRT2576000	hsa-miR-3647-3p	CLIP-seq
MIRT2576001	hsa-miR-3655	CLIP-seq
MIRT2576002	hsa-miR-374c	CLIP-seq
MIRT2685589	hsa-miR-3913-3p	CLIP-seq
MIRT2576003	hsa-miR-3929	CLIP-seq
MIRT2685590	hsa-miR-3973	CLIP-seq
MIRT2576005	hsa-miR-4311	CLIP-seq
MIRT2576006	hsa-miR-4312	CLIP-seq
MIRT2576007	hsa-miR-4419b	CLIP-seq
MIRT1167093	hsa-miR-4436b-3p	CLIP-seq
MIRT1167079	hsa-miR-4465	CLIP-seq
MIRT2576008	hsa-miR-4478	CLIP-seq
MIRT2576009	hsa-miR-4515	CLIP-seq
MIRT1167095	hsa-miR-4528	CLIP-seq
MIRT2576010	hsa-miR-4633-3p	CLIP-seq
MIRT1167080	hsa-miR-4648	CLIP-seq
MIRT2576012	hsa-miR-4682	CLIP-seq
MIRT2576014	hsa-miR-4717-3p	CLIP-seq
MIRT1167083	hsa-miR-4725-5p	CLIP-seq
MIRT2576015	hsa-miR-4726-3p	CLIP-seq
MIRT2576016	hsa-miR-4740-5p	CLIP-seq
MIRT2576017	hsa-miR-4802-3p	CLIP-seq
MIRT2576018	hsa-miR-485-5p	CLIP-seq
MIRT2685591	hsa-miR-489	CLIP-seq
MIRT1167084	hsa-miR-504	CLIP-seq
MIRT2576019	hsa-miR-511	CLIP-seq
MIRT2685592	hsa-miR-513a-3p	CLIP-seq
MIRT2685593	hsa-miR-519a	CLIP-seq
MIRT2685594	hsa-miR-519b-3p	CLIP-seq
MIRT2685595	hsa-miR-519c-3p	CLIP-seq
MIRT2685596	hsa-miR-519d	CLIP-seq
MIRT2685597	hsa-miR-520g	CLIP-seq
MIRT2685598	hsa-miR-520h	CLIP-seq
MIRT2576021	hsa-miR-578	CLIP-seq
MIRT2277186	hsa-miR-583	CLIP-seq
MIRT2576022	hsa-miR-633	CLIP-seq
MIRT2576023	hsa-miR-655	CLIP-seq
MIRT2576024	hsa-miR-663b	CLIP-seq
MIRT1167102	hsa-miR-761	CLIP-seq
MIRT2576025	hsa-miR-802	CLIP-seq
MIRT2685599	hsa-miR-93	CLIP-seq

Transcription factors

Show/Hide all(1)

Transcription factor	Regulation	Reference
MYCN	Repression	24403858

Show/Hide all(15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	11875718
GO:0000785	Component	Chromatin	ISA
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	8425219
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	21873635
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	21873635
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	11875718
GO:0005515	Function	Protein binding	IPI	16189514, 25416956, 25609649, 27705803
GO:0005634	Component	Nucleus	TAS	8425219
GO:0005654	Component	Nucleoplasm	IDA
GO:0005730	Component	Nucleolus	IDA
GO:0005829	Component	Cytosol	IDA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA	21873635
GO:0046983	Function	Protein dimerization activity	IEA
GO:0090575	Component	RNA polymerase II transcription regulator complex	IDA	8425219

MIM	HGNC	e!Ensembl
600020	7534	ENSG00000119950

Protein

UniProt ID

P50539

Protein name

Max-interacting protein 1 (Max interactor 1) (Class C basic helix-loop-helix protein 11) (bHLHc11)

Protein function

Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00010	HLH	68 → 120	Helix-loop-helix DNA-binding domain	Domain

Tissue specificity

TISSUE SPECIFICITY: High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle.

Sequence

MERVKMINVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSG
SSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLE
EAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVD
VESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS

Sequence length

228

Interactions

View interactions

Show/Hide Causal Diseases (3)

Disease term	Disease name	dbSNP ID	References
Causal
Kidney disease	Kidney Diseases	rs74315342, rs749740335, rs757649673, rs112417755, rs35138315	23316056
Neurofibrosarcoma	Neurofibrosarcoma	rs137852604
Prostate cancer	Malignant neoplasm of prostate	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	7773287

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Evidence	Source
Unknown
Multiple myeloma	Multiple myeloma	MM cells lacking PSMC6 also developed resistance against Carfilzomib (CAR)	GWAS, CBGDA
Bipolar Disorder	Bipolar Disorder		GWAS

Show/Hide Text Mining Associations (22)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma	Associate	18493233
Brain Neoplasms	Associate	24376632
Carcinogenesis	Associate	11875718, 19018165
Carcinoma Non Small Cell Lung	Associate	35149174
Carcinoma Renal Cell	Stimulate	19018165
Desmoplastic Small Round Cell Tumor	Associate	32873880
Glioblastoma	Associate	11875718, 24376632, 26943771
Glioma	Inhibit	24376632
Glioma	Associate	37934565
Hypoxia	Associate	18087215
Kidney Neoplasms	Associate	19018165
Lung Neoplasms	Associate	29507620, 35149174
Lung Neoplasms	Inhibit	35501353
Medulloblastoma	Associate	23291781
Neoplasms	Inhibit	10470286, 11875718, 17559306, 29507620, 8838813
Neoplasms	Associate	10497252, 18493233, 19018165, 32873880, 39287260, 9460998
Neuroblastoma	Associate	24403858
Neurofibrosarcoma	Associate	10470286
Prostatic Hyperplasia	Associate	11351349
Prostatic Neoplasms	Associate	11351349, 24713434, 32784653, 33279858, 39287260
Prostatitis	Associate	11351349
Sleep Deprivation	Associate	17559306

MXI1 (MAX interactor 1, dimerization protein)