MTX1 (metaxin 1)

Gene

• Entrez ID: 4580
• Gene name: Metaxin 1
• Gene symbol: MTX1
• Synonyms (NCBI Gene): MTX, MTXN
• Chromosome: 1
• Chromosome location: 1q22

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT002819	hsa-miR-1-3p	pSILAC	18668040
MIRT002819	hsa-miR-1-3p	Microarray	15685193
MIRT002819	hsa-miR-1-3p	Proteomics	18668040
MIRT002819	hsa-miR-1-3p	Microarray	15685193
MIRT029412	hsa-miR-26b-5p	Microarray	19088304
MIRT1165785	hsa-miR-1	CLIP-seq
MIRT1165786	hsa-miR-1293	CLIP-seq
MIRT1165787	hsa-miR-1299	CLIP-seq
MIRT1165788	hsa-miR-151-5p	CLIP-seq
MIRT1165789	hsa-miR-151b	CLIP-seq
MIRT1165790	hsa-miR-206	CLIP-seq
MIRT1165791	hsa-miR-3065-3p	CLIP-seq
MIRT1165792	hsa-miR-3119	CLIP-seq
MIRT1165793	hsa-miR-3612	CLIP-seq
MIRT1165794	hsa-miR-3622a-5p	CLIP-seq
MIRT1165795	hsa-miR-3673	CLIP-seq
MIRT1165796	hsa-miR-4302	CLIP-seq
MIRT1165797	hsa-miR-4314	CLIP-seq
MIRT1165798	hsa-miR-4481	CLIP-seq
MIRT1165799	hsa-miR-4483	CLIP-seq
MIRT1165800	hsa-miR-4669	CLIP-seq
MIRT1165801	hsa-miR-4693-3p	CLIP-seq
MIRT1165802	hsa-miR-4695-5p	CLIP-seq
MIRT1165803	hsa-miR-4697-3p	CLIP-seq
MIRT1165804	hsa-miR-4712-3p	CLIP-seq
MIRT1165805	hsa-miR-4718	CLIP-seq
MIRT1165806	hsa-miR-4745-5p	CLIP-seq
MIRT1165807	hsa-miR-4757-5p	CLIP-seq
MIRT1165808	hsa-miR-4758-5p	CLIP-seq
MIRT1165809	hsa-miR-4778-5p	CLIP-seq
MIRT1165810	hsa-miR-564	CLIP-seq
MIRT1165811	hsa-miR-613	CLIP-seq
MIRT1165812	hsa-miR-650	CLIP-seq
MIRT1165813	hsa-miR-875-3p	CLIP-seq
MIRT1165814	hsa-miR-885-3p	CLIP-seq
MIRT1165785	hsa-miR-1	CLIP-seq
MIRT1165786	hsa-miR-1293	CLIP-seq
MIRT1165787	hsa-miR-1299	CLIP-seq
MIRT1165790	hsa-miR-206	CLIP-seq
MIRT1165791	hsa-miR-3065-3p	CLIP-seq
MIRT1165792	hsa-miR-3119	CLIP-seq
MIRT1165793	hsa-miR-3612	CLIP-seq
MIRT1165794	hsa-miR-3622a-5p	CLIP-seq
MIRT1165795	hsa-miR-3673	CLIP-seq
MIRT1165797	hsa-miR-4314	CLIP-seq
MIRT1165799	hsa-miR-4483	CLIP-seq
MIRT1165802	hsa-miR-4695-5p	CLIP-seq
MIRT1165807	hsa-miR-4757-5p	CLIP-seq
MIRT1165809	hsa-miR-4778-5p	CLIP-seq
MIRT1165810	hsa-miR-564	CLIP-seq
MIRT1165811	hsa-miR-613	CLIP-seq
MIRT1165812	hsa-miR-650	CLIP-seq
MIRT1165813	hsa-miR-875-3p	CLIP-seq
MIRT1165814	hsa-miR-885-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001401	Component	SAM complex	HDA	26477565
GO:0001401	Component	SAM complex	IBA
GO:0001401	Component	SAM complex	IEA
GO:0001401	Component	SAM complex	IPI	17510655
GO:0005515	Function	Protein binding	IPI	31644573
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IEA
GO:0005741	Component	Mitochondrial outer membrane	IEA
GO:0005741	Component	Mitochondrial outer membrane	NAS	31387448
GO:0007005	Process	Mitochondrion organization	IBA
GO:0007007	Process	Inner mitochondrial membrane organization	IC	26477565
GO:0007595	Process	Lactation	IEA
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	TAS	8660965
GO:0045040	Process	Protein insertion into mitochondrial outer membrane	NAS	31387448
GO:0140275	Component	MIB complex	HDA	26477565

Other IDs

• MIM: 600605
• HGNC: 7504
• e!Ensembl: ENSG00000173171

Protein

• UniProt ID: Q13505
• Protein name: Metaxin-1 (Mitochondrial outer membrane import complex protein 1)
• Protein function: Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity).
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF10568	Tom37	172 → 293	Outer mitochondrial membrane transport complex protein	Family
  PF17171	GST_C_6	323 → 386	Glutathione S-transferase, C-terminal domain	Domain

• Sequence:

  MLLGGPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAAPSGVRGSTWTRR
  RDSPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGISPGPLTAT
  IGGAVAGGGPRQGRAEAHKEVFPGQRVGKMAAPMELFCWSGGWGLPSVDLDSLAVLTYAR
  FTGAPLKVHKISNPWQSPSGTLPALRTSHGEVISVPHKIITHLRKEKYNADYDLSARQGA
  DTLAFMSLLEEKLLPVLVHTFWIDTKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYMERL
  QLLTGEHRPEDEEELEKELYREARECLTLLSQRLGSQKFFFGDAPASLDAFVFSYLALLL
  QAKLPSGKLQVHLRGLHNLCAYCTHILSLYFPWDGAEVPPQRQTPAGPETEEEPYRRRNQ
  ILSVLAGLAAMVGYALLSGIVSIQRATPARAPGTRTLGMAEEDEEE

• Sequence length: 466

Pathways

KEGG:

Mitophagy - animal