Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	4580
Gene name Gene Name - the full gene name approved by the HGNC.	Metaxin 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MTX1
Synonyms (NCBI Gene) Gene synonyms aliases	MTX, MTXN
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1q22

Show/Hide all(54)

miRTarBase ID	miRNA	Experiments	Reference
MIRT002819	hsa-miR-1-3p	pSILAC	18668040
MIRT002819	hsa-miR-1-3p	Microarray	15685193
MIRT002819	hsa-miR-1-3p	Proteomics	18668040
MIRT002819	hsa-miR-1-3p	Microarray	15685193
MIRT029412	hsa-miR-26b-5p	Microarray	19088304
MIRT1165785	hsa-miR-1	CLIP-seq
MIRT1165786	hsa-miR-1293	CLIP-seq
MIRT1165787	hsa-miR-1299	CLIP-seq
MIRT1165788	hsa-miR-151-5p	CLIP-seq
MIRT1165789	hsa-miR-151b	CLIP-seq
MIRT1165790	hsa-miR-206	CLIP-seq
MIRT1165791	hsa-miR-3065-3p	CLIP-seq
MIRT1165792	hsa-miR-3119	CLIP-seq
MIRT1165793	hsa-miR-3612	CLIP-seq
MIRT1165794	hsa-miR-3622a-5p	CLIP-seq
MIRT1165795	hsa-miR-3673	CLIP-seq
MIRT1165796	hsa-miR-4302	CLIP-seq
MIRT1165797	hsa-miR-4314	CLIP-seq
MIRT1165798	hsa-miR-4481	CLIP-seq
MIRT1165799	hsa-miR-4483	CLIP-seq
MIRT1165800	hsa-miR-4669	CLIP-seq
MIRT1165801	hsa-miR-4693-3p	CLIP-seq
MIRT1165802	hsa-miR-4695-5p	CLIP-seq
MIRT1165803	hsa-miR-4697-3p	CLIP-seq
MIRT1165804	hsa-miR-4712-3p	CLIP-seq
MIRT1165805	hsa-miR-4718	CLIP-seq
MIRT1165806	hsa-miR-4745-5p	CLIP-seq
MIRT1165807	hsa-miR-4757-5p	CLIP-seq
MIRT1165808	hsa-miR-4758-5p	CLIP-seq
MIRT1165809	hsa-miR-4778-5p	CLIP-seq
MIRT1165810	hsa-miR-564	CLIP-seq
MIRT1165811	hsa-miR-613	CLIP-seq
MIRT1165812	hsa-miR-650	CLIP-seq
MIRT1165813	hsa-miR-875-3p	CLIP-seq
MIRT1165814	hsa-miR-885-3p	CLIP-seq
MIRT1165785	hsa-miR-1	CLIP-seq
MIRT1165786	hsa-miR-1293	CLIP-seq
MIRT1165787	hsa-miR-1299	CLIP-seq
MIRT1165790	hsa-miR-206	CLIP-seq
MIRT1165791	hsa-miR-3065-3p	CLIP-seq
MIRT1165792	hsa-miR-3119	CLIP-seq
MIRT1165793	hsa-miR-3612	CLIP-seq
MIRT1165794	hsa-miR-3622a-5p	CLIP-seq
MIRT1165795	hsa-miR-3673	CLIP-seq
MIRT1165797	hsa-miR-4314	CLIP-seq
MIRT1165799	hsa-miR-4483	CLIP-seq
MIRT1165802	hsa-miR-4695-5p	CLIP-seq
MIRT1165807	hsa-miR-4757-5p	CLIP-seq
MIRT1165809	hsa-miR-4778-5p	CLIP-seq
MIRT1165810	hsa-miR-564	CLIP-seq
MIRT1165811	hsa-miR-613	CLIP-seq
MIRT1165812	hsa-miR-650	CLIP-seq
MIRT1165813	hsa-miR-875-3p	CLIP-seq
MIRT1165814	hsa-miR-885-3p	CLIP-seq

Show/Hide all(11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001401	Component	SAM complex	HDA	26477565
GO:0001401	Component	SAM complex	IBA	21873635
GO:0003674	Function	Molecular_function	ND
GO:0005515	Function	Protein binding	IPI	31644573
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0007005	Process	Mitochondrion organization	IBA	21873635
GO:0007007	Process	Inner mitochondrial membrane organization	IC	26477565
GO:0007595	Process	Lactation	IEA
GO:0015031	Process	Protein transport	IEA
GO:0016021	Component	Integral component of membrane	TAS	8660965
GO:0140275	Component	MIB complex	HDA	26477565

MIM	HGNC	e!Ensembl
600605	7504	ENSG00000173171

Protein

UniProt ID

Q13505

Protein name

Metaxin-1 (Mitochondrial outer membrane import complex protein 1)

Protein function

Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF10568	Tom37	172 → 293	Outer mitochondrial membrane transport complex protein	Family
PF17171	GST_C_6	323 → 386	Glutathione S-transferase, C-terminal domain	Domain

Sequence

MLLGGPPRSPRSGTSPKGPWSSTGHVQFGKSPQTWPRRTRPRSPEPAAPSGVRGSTWTRR
RDSPRRAGPTALSRYVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGISPGPLTAT
IGGAVAGGGPRQGRAEAHKEVFPGQRVGKMAAPMELFCWSGGWGLPSVDLDSLAVLTYAR
FTGAPLKVHKISNPWQSPSGTLPALRTSHGEVISVPHKIITHLRKEKYNADYDLSARQGA
DTLAFMSLLEEKLLPVLVHTFWIDTKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYMERL
QLLTGEHRPEDEEELEKELYREARECLTLLSQRLGSQKFFFGDAPASLDAFVFSYLALLL
QAKLPSGKLQVHLRGLHNLCAYCTHILSLYFPWDGAEVPPQRQTPAGPETEEEPYRRRNQ
ILSVLAGLAAMVGYALLSGIVSIQRATPARAPGTRTLGMAEEDEEE

Sequence length

466

Interactions

View interactions

	KEGG
	Mitophagy - animal

Show/Hide Causal Diseases (7)

Disease term	Disease name	dbSNP ID	References
Causal
Breast carcinoma	Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451 View all (71 more)	27197191
Colonic neoplasms	Malignant tumor of colon	rs267607789, rs774277300, rs781222233, rs1060502734, rs1060503333, rs1339238483	27197191
Colorectal cancer	Colorectal Carcinoma, Adenocarcinoma of large intestine	rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800 View all (467 more)	27197191
Colorectal neoplasms	Colorectal Neoplasms, Malignant neoplasm of large intestine	rs28929483, rs63751108, rs28929484, rs63749831, rs63750047, rs63751207, rs63749811, rs1553350126, rs63750875, rs63750955, rs587776706, rs63750871, rs587776715, rs63751466, rs63750049 View all (1682 more)	27197191
Lung carcinoma	Squamous cell carcinoma of lung, Carcinoma of lung	rs1805076, rs121909071, rs121913530, rs112445441, rs121913529, rs121913535, rs121913297, rs121913279, rs104886003, rs397516975, rs11554290, rs121913364, rs121913351, rs121913369, rs121913355 View all (44 more)	27197191
Lung adenocarcinoma	Adenocarcinoma of lung (disorder)	rs28934576, rs121913530, rs397516975, rs587776805, rs121913469, rs121913364, rs121913351, rs121913366, rs397516896, rs397516977, rs397516981, rs397517127, rs121913344, rs727504233, rs121913370 View all (5 more)	27197191
Prostate cancer	Prostate carcinoma	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	27197191

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Gout	Gout			GWAS

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References
Associations from Text Mining
Asymptomatic Diseases	Associate	36221101
Esophageal Neoplasms	Associate	29028942
Gout	Associate	36221101
Metabolic Syndrome	Associate	34638981

MTX1 (metaxin 1)