Gene Gene information from NCBI Gene database.
Entrez ID 4549
Gene name Mitochondrially encoded 12S RNA
Gene symbol RNR1
Synonyms (NCBI Gene)
MTRNR1
Chromosome MT
Chromosome location -
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
561000 7470 HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
A0A0C5B5G6
Protein name Mitochondrial-derived peptide MOTS-c (Mitochondrial open reading frame of the 12S rRNA-c)
Protein function Regulates insulin sensitivity and metabolic homeostasis (PubMed:25738459, PubMed:33468709). Inhibits the folate cycle, thereby reducing de novo purine biosynthesis which leads to the accumulation of the de novo purine synthesis intermediate 5-am
Family and domains
Tissue specificity TISSUE SPECIFICITY: Detected in plasma (at protein level) (PubMed:25738459, PubMed:32182209). Also expressed in skeletal muscle (at protein level) (PubMed:32182209). {ECO:0000269|PubMed:25738459, ECO:0000269|PubMed:32182209}.
Sequence
MRWQEMGYIFYPRKLR
Sequence length 16
Interactions View interactions