MTR (5-methyltetrahydrofolate-homocysteine methyltransferase)

Gene

• Entrez ID: 4548
• Gene name: 5-methyltetrahydrofolate-homocysteine methyltransferase
• Gene symbol: MTR
• Synonyms (NCBI Gene): HMAG, MS, cblG
• Chromosome: 1
• Chromosome location: 1q43
• Summary: This gene encodes the 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs1805087	A>G	Benign, risk-factor, uncertain-significance	Coding sequence variant, missense variant
rs116836001	C>G,T	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Missense variant, coding sequence variant
rs121913578	C>T	Likely-pathogenic, pathogenic, pathogenic-likely-pathogenic	Missense variant, coding sequence variant
rs121913580	C>T	Pathogenic	Stop gained, coding sequence variant
rs121913581	G>T	Pathogenic	Stop gained, coding sequence variant
rs121913582	G>C	Pathogenic	Missense variant, coding sequence variant
rs145006491	G>A,T	Conflicting-interpretations-of-pathogenicity, uncertain-significance, benign	Coding sequence variant, 5 prime UTR variant, missense variant
rs201718371	C>T	Pathogenic	Coding sequence variant, stop gained
rs794727395	TG>-	Pathogenic	Coding sequence variant, frameshift variant
rs797044443	AAT>-	Pathogenic	Coding sequence variant, inframe deletion
rs797044444	TC>-	Pathogenic	Coding sequence variant, intron variant, frameshift variant
rs797044445	->A	Pathogenic	Coding sequence variant, frameshift variant
rs1064796330	A>-	Likely-pathogenic	Coding sequence variant, frameshift variant
rs1190777785	G>C	Likely-pathogenic	5 prime UTR variant, upstream transcript variant, coding sequence variant, missense variant, genic upstream transcript variant
rs1242741686	A>G	Likely-pathogenic	Missense variant, coding sequence variant
rs1346847201	C>-	Pathogenic	Coding sequence variant, frameshift variant
rs1367402633	AT>-	Likely-pathogenic	Genic upstream transcript variant, 5 prime UTR variant, frameshift variant, initiator codon variant, coding sequence variant
rs1413989228	G>A	Likely-pathogenic	Missense variant, intron variant, coding sequence variant
rs1572218599	G>C	Likely-pathogenic	Splice donor variant, intron variant
rs1572278166	->ATCA	Pathogenic	Coding sequence variant, frameshift variant
rs1572309822	A>-	Pathogenic	Coding sequence variant, intron variant, stop gained

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT047589	hsa-miR-10a-5p	CLASH	23622248
MIRT044357	hsa-miR-106b-5p	CLASH	23622248
MIRT042208	hsa-miR-484	CLASH	23622248
MIRT041354	hsa-miR-193b-3p	CLASH	23622248
MIRT041354	hsa-miR-193b-3p	CLASH	23622248
MIRT497504	hsa-miR-4635	PAR-CLIP	22291592
MIRT497503	hsa-miR-548ao-5p	PAR-CLIP	22291592
MIRT497502	hsa-miR-548ax	PAR-CLIP	22291592
MIRT497501	hsa-miR-5585-5p	PAR-CLIP	22291592
MIRT497500	hsa-miR-3616-5p	PAR-CLIP	22291592
MIRT497499	hsa-miR-573	PAR-CLIP	22291592
MIRT497498	hsa-miR-3064-3p	PAR-CLIP	22291592
MIRT497497	hsa-miR-4715-3p	PAR-CLIP	22291592
MIRT440197	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440197	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT134329	hsa-miR-30a-5p	HITS-CLIP	22473208
MIRT134332	hsa-miR-30b-5p	HITS-CLIP	22473208
MIRT134330	hsa-miR-30c-5p	HITS-CLIP	22473208
MIRT134331	hsa-miR-30d-5p	HITS-CLIP	22473208
MIRT134335	hsa-miR-30e-5p	HITS-CLIP	22473208
MIRT497504	hsa-miR-4635	PAR-CLIP	22291592
MIRT497503	hsa-miR-548ao-5p	PAR-CLIP	22291592
MIRT497502	hsa-miR-548ax	PAR-CLIP	22291592
MIRT497501	hsa-miR-5585-5p	PAR-CLIP	22291592
MIRT497500	hsa-miR-3616-5p	PAR-CLIP	22291592
MIRT497499	hsa-miR-573	PAR-CLIP	22291592
MIRT497498	hsa-miR-3064-3p	PAR-CLIP	22291592
MIRT497497	hsa-miR-4715-3p	PAR-CLIP	22291592
MIRT1164912	hsa-let-7a	CLIP-seq
MIRT1164913	hsa-let-7b	CLIP-seq
MIRT1164914	hsa-let-7c	CLIP-seq
MIRT1164915	hsa-let-7d	CLIP-seq
MIRT1164916	hsa-let-7e	CLIP-seq
MIRT1164917	hsa-let-7f	CLIP-seq
MIRT1164918	hsa-let-7g	CLIP-seq
MIRT1164919	hsa-let-7i	CLIP-seq
MIRT1164920	hsa-miR-103b	CLIP-seq
MIRT1164921	hsa-miR-1184	CLIP-seq
MIRT1164922	hsa-miR-1200	CLIP-seq
MIRT1164923	hsa-miR-1207-5p	CLIP-seq
MIRT1164924	hsa-miR-1224-3p	CLIP-seq
MIRT1164925	hsa-miR-124	CLIP-seq
MIRT1164926	hsa-miR-1255a	CLIP-seq
MIRT1164927	hsa-miR-1255b	CLIP-seq
MIRT1164928	hsa-miR-1260	CLIP-seq
MIRT1164929	hsa-miR-1260b	CLIP-seq
MIRT1164930	hsa-miR-1262	CLIP-seq
MIRT1164931	hsa-miR-1280	CLIP-seq
MIRT1164932	hsa-miR-1283	CLIP-seq
MIRT1164933	hsa-miR-1293	CLIP-seq
MIRT1164934	hsa-miR-1294	CLIP-seq
MIRT1164935	hsa-miR-129-5p	CLIP-seq
MIRT1164936	hsa-miR-1298	CLIP-seq
MIRT1164937	hsa-miR-1324	CLIP-seq
MIRT1164938	hsa-miR-141	CLIP-seq
MIRT1164939	hsa-miR-154	CLIP-seq
MIRT1164940	hsa-miR-15a	CLIP-seq
MIRT1164941	hsa-miR-15b	CLIP-seq
MIRT1164942	hsa-miR-16	CLIP-seq
MIRT1164943	hsa-miR-1827	CLIP-seq
MIRT1164944	hsa-miR-195	CLIP-seq
MIRT1164945	hsa-miR-1976	CLIP-seq
MIRT1164946	hsa-miR-19a	CLIP-seq
MIRT1164947	hsa-miR-19b	CLIP-seq
MIRT1164948	hsa-miR-200a	CLIP-seq
MIRT1164949	hsa-miR-200b	CLIP-seq
MIRT1164950	hsa-miR-200c	CLIP-seq
MIRT1164951	hsa-miR-202	CLIP-seq
MIRT1164952	hsa-miR-203	CLIP-seq
MIRT1164953	hsa-miR-205	CLIP-seq
MIRT1164954	hsa-miR-2114	CLIP-seq
MIRT1164955	hsa-miR-2115	CLIP-seq
MIRT1164956	hsa-miR-214	CLIP-seq
MIRT1164957	hsa-miR-2276	CLIP-seq
MIRT1164958	hsa-miR-2355-5p	CLIP-seq
MIRT1164959	hsa-miR-24	CLIP-seq
MIRT1164960	hsa-miR-3074-5p	CLIP-seq
MIRT1164961	hsa-miR-30a	CLIP-seq
MIRT1164962	hsa-miR-30b	CLIP-seq
MIRT1164963	hsa-miR-30c	CLIP-seq
MIRT1164964	hsa-miR-30d	CLIP-seq
MIRT1164965	hsa-miR-30e	CLIP-seq
MIRT1164966	hsa-miR-3119	CLIP-seq
MIRT1164967	hsa-miR-3120-3p	CLIP-seq
MIRT1164968	hsa-miR-3124-3p	CLIP-seq
MIRT1164969	hsa-miR-3125	CLIP-seq
MIRT1164970	hsa-miR-3127-5p	CLIP-seq
MIRT1164971	hsa-miR-3140-3p	CLIP-seq
MIRT1164972	hsa-miR-3140-5p	CLIP-seq
MIRT1164973	hsa-miR-3148	CLIP-seq
MIRT1164974	hsa-miR-3149	CLIP-seq
MIRT1164975	hsa-miR-3152-5p	CLIP-seq
MIRT1164976	hsa-miR-3153	CLIP-seq
MIRT1164977	hsa-miR-3155	CLIP-seq
MIRT1164978	hsa-miR-3155b	CLIP-seq
MIRT1164979	hsa-miR-3157-3p	CLIP-seq
MIRT1164980	hsa-miR-3158-3p	CLIP-seq
MIRT1164981	hsa-miR-3168	CLIP-seq
MIRT1164982	hsa-miR-3170	CLIP-seq
MIRT1164983	hsa-miR-3180-5p	CLIP-seq
MIRT1164984	hsa-miR-3184	CLIP-seq
MIRT1164985	hsa-miR-3192	CLIP-seq
MIRT1164986	hsa-miR-3202	CLIP-seq
MIRT1164987	hsa-miR-326	CLIP-seq
MIRT1164988	hsa-miR-330-5p	CLIP-seq
MIRT1164989	hsa-miR-342-5p	CLIP-seq
MIRT1164990	hsa-miR-34c-3p	CLIP-seq
MIRT1164991	hsa-miR-3545-3p	CLIP-seq
MIRT1164992	hsa-miR-3612	CLIP-seq
MIRT1164993	hsa-miR-3614-5p	CLIP-seq
MIRT1164994	hsa-miR-3617	CLIP-seq
MIRT1164995	hsa-miR-3619-5p	CLIP-seq
MIRT1164996	hsa-miR-3622b-5p	CLIP-seq
MIRT1164997	hsa-miR-3646	CLIP-seq
MIRT1164998	hsa-miR-3647-3p	CLIP-seq
MIRT1164999	hsa-miR-3663-3p	CLIP-seq
MIRT1165000	hsa-miR-3664-5p	CLIP-seq
MIRT1165001	hsa-miR-3689a-3p	CLIP-seq
MIRT1165002	hsa-miR-3689c	CLIP-seq
MIRT1165003	hsa-miR-3690	CLIP-seq
MIRT1165004	hsa-miR-369-3p	CLIP-seq
MIRT1165005	hsa-miR-370	CLIP-seq
MIRT1165006	hsa-miR-3714	CLIP-seq
MIRT1165007	hsa-miR-371-5p	CLIP-seq
MIRT1165008	hsa-miR-374a	CLIP-seq
MIRT1165009	hsa-miR-374b	CLIP-seq
MIRT1165010	hsa-miR-377	CLIP-seq
MIRT1165011	hsa-miR-380	CLIP-seq
MIRT1165012	hsa-miR-3910	CLIP-seq
MIRT1165013	hsa-miR-3914	CLIP-seq
MIRT1165014	hsa-miR-3916	CLIP-seq
MIRT1165015	hsa-miR-3928	CLIP-seq
MIRT1165016	hsa-miR-3929	CLIP-seq
MIRT1165017	hsa-miR-423-3p	CLIP-seq
MIRT1165018	hsa-miR-423-5p	CLIP-seq
MIRT1165019	hsa-miR-424	CLIP-seq
MIRT1165020	hsa-miR-4251	CLIP-seq
MIRT1165021	hsa-miR-4254	CLIP-seq
MIRT1165022	hsa-miR-4260	CLIP-seq
MIRT1165023	hsa-miR-4261	CLIP-seq
MIRT1165024	hsa-miR-4263	CLIP-seq
MIRT1165025	hsa-miR-4274	CLIP-seq
MIRT1165026	hsa-miR-4277	CLIP-seq
MIRT1165027	hsa-miR-4279	CLIP-seq
MIRT1165028	hsa-miR-4284	CLIP-seq
MIRT1165029	hsa-miR-429	CLIP-seq
MIRT1165030	hsa-miR-4291	CLIP-seq
MIRT1165031	hsa-miR-4303	CLIP-seq
MIRT1165032	hsa-miR-431	CLIP-seq
MIRT1165033	hsa-miR-4314	CLIP-seq
MIRT1165034	hsa-miR-4316	CLIP-seq
MIRT1165035	hsa-miR-4329	CLIP-seq
MIRT1165036	hsa-miR-4418	CLIP-seq
MIRT1165037	hsa-miR-4419a	CLIP-seq
MIRT1165038	hsa-miR-4419b	CLIP-seq
MIRT1165039	hsa-miR-4427	CLIP-seq
MIRT1165040	hsa-miR-4436b-5p	CLIP-seq
MIRT1165041	hsa-miR-4443	CLIP-seq
MIRT1165042	hsa-miR-4446-3p	CLIP-seq
MIRT1165043	hsa-miR-4455	CLIP-seq
MIRT1165044	hsa-miR-4458	CLIP-seq
MIRT1165045	hsa-miR-4459	CLIP-seq
MIRT1165046	hsa-miR-4468	CLIP-seq
MIRT1165047	hsa-miR-4477b	CLIP-seq
MIRT1165048	hsa-miR-4478	CLIP-seq
MIRT1165049	hsa-miR-4483	CLIP-seq
MIRT1165050	hsa-miR-4495	CLIP-seq
MIRT1165051	hsa-miR-4500	CLIP-seq
MIRT1165052	hsa-miR-4510	CLIP-seq
MIRT1165053	hsa-miR-4517	CLIP-seq
MIRT1165054	hsa-miR-451b	CLIP-seq
MIRT1165055	hsa-miR-4533	CLIP-seq
MIRT1165056	hsa-miR-4642	CLIP-seq
MIRT1165057	hsa-miR-4643	CLIP-seq
MIRT1165058	hsa-miR-4646-5p	CLIP-seq
MIRT1165059	hsa-miR-4649-3p	CLIP-seq
MIRT1165060	hsa-miR-4651	CLIP-seq
MIRT1165061	hsa-miR-4655-5p	CLIP-seq
MIRT1165062	hsa-miR-4659a-3p	CLIP-seq
MIRT1165063	hsa-miR-4659a-5p	CLIP-seq
MIRT1165064	hsa-miR-4659b-3p	CLIP-seq
MIRT1165065	hsa-miR-4659b-5p	CLIP-seq
MIRT1165066	hsa-miR-466	CLIP-seq
MIRT1165067	hsa-miR-4664-5p	CLIP-seq
MIRT1165068	hsa-miR-4668-5p	CLIP-seq
MIRT1165069	hsa-miR-4694-3p	CLIP-seq
MIRT1165070	hsa-miR-4695-5p	CLIP-seq
MIRT1165071	hsa-miR-4701-3p	CLIP-seq
MIRT1165072	hsa-miR-4703-3p	CLIP-seq
MIRT1165073	hsa-miR-4714-5p	CLIP-seq
MIRT1165074	hsa-miR-4717-3p	CLIP-seq
MIRT1165075	hsa-miR-4722-3p	CLIP-seq
MIRT1165076	hsa-miR-4722-5p	CLIP-seq
MIRT1165077	hsa-miR-4724-3p	CLIP-seq
MIRT1165078	hsa-miR-4724-5p	CLIP-seq
MIRT1165079	hsa-miR-4728-5p	CLIP-seq
MIRT1165080	hsa-miR-4732-5p	CLIP-seq
MIRT1165081	hsa-miR-4755-3p	CLIP-seq
MIRT1165082	hsa-miR-4762-3p	CLIP-seq
MIRT1165083	hsa-miR-4763-3p	CLIP-seq
MIRT1165084	hsa-miR-4768-3p	CLIP-seq
MIRT1165085	hsa-miR-4768-5p	CLIP-seq
MIRT1165086	hsa-miR-4773	CLIP-seq
MIRT1165087	hsa-miR-4774-3p	CLIP-seq
MIRT1165088	hsa-miR-4778-3p	CLIP-seq
MIRT1165089	hsa-miR-4789-3p	CLIP-seq
MIRT1165090	hsa-miR-4802-3p	CLIP-seq
MIRT1165091	hsa-miR-485-5p	CLIP-seq
MIRT1165092	hsa-miR-487a	CLIP-seq
MIRT1165093	hsa-miR-493	CLIP-seq
MIRT1165094	hsa-miR-497	CLIP-seq
MIRT1165095	hsa-miR-500a	CLIP-seq
MIRT1165096	hsa-miR-501-3p	CLIP-seq
MIRT1165097	hsa-miR-502-3p	CLIP-seq
MIRT1165098	hsa-miR-506	CLIP-seq
MIRT1165099	hsa-miR-509-3-5p	CLIP-seq
MIRT1165100	hsa-miR-509-5p	CLIP-seq
MIRT1165101	hsa-miR-512-5p	CLIP-seq
MIRT1165102	hsa-miR-514	CLIP-seq
MIRT1165103	hsa-miR-514b-3p	CLIP-seq
MIRT1165104	hsa-miR-516b	CLIP-seq
MIRT1165105	hsa-miR-520a-5p	CLIP-seq
MIRT1165106	hsa-miR-525-5p	CLIP-seq
MIRT1165107	hsa-miR-532-3p	CLIP-seq
MIRT1165108	hsa-miR-541	CLIP-seq
MIRT1165109	hsa-miR-548a-3p	CLIP-seq
MIRT1165110	hsa-miR-548ae	CLIP-seq
MIRT1165111	hsa-miR-548aj	CLIP-seq
MIRT1165112	hsa-miR-548am	CLIP-seq
MIRT1165113	hsa-miR-548an	CLIP-seq
MIRT1165114	hsa-miR-548e	CLIP-seq
MIRT1165115	hsa-miR-548f	CLIP-seq
MIRT1165116	hsa-miR-548g	CLIP-seq
MIRT1165117	hsa-miR-548l	CLIP-seq
MIRT1165118	hsa-miR-548x	CLIP-seq
MIRT1165119	hsa-miR-562	CLIP-seq
MIRT1165120	hsa-miR-577	CLIP-seq
MIRT1165121	hsa-miR-608	CLIP-seq
MIRT1165122	hsa-miR-609	CLIP-seq
MIRT1165123	hsa-miR-635	CLIP-seq
MIRT1165124	hsa-miR-641	CLIP-seq
MIRT1165125	hsa-miR-650	CLIP-seq
MIRT1165126	hsa-miR-653	CLIP-seq
MIRT1165127	hsa-miR-654-5p	CLIP-seq
MIRT1165128	hsa-miR-664	CLIP-seq
MIRT1165129	hsa-miR-665	CLIP-seq
MIRT1165130	hsa-miR-758	CLIP-seq
MIRT1165131	hsa-miR-761	CLIP-seq
MIRT1165132	hsa-miR-767-3p	CLIP-seq
MIRT1165133	hsa-miR-875-3p	CLIP-seq
MIRT1165134	hsa-miR-885-3p	CLIP-seq
MIRT1165135	hsa-miR-889	CLIP-seq
MIRT1165136	hsa-miR-922	CLIP-seq
MIRT1165137	hsa-miR-935	CLIP-seq
MIRT1165138	hsa-miR-940	CLIP-seq
MIRT1165139	hsa-miR-98	CLIP-seq
MIRT1164920	hsa-miR-103b	CLIP-seq
MIRT1164923	hsa-miR-1207-5p	CLIP-seq
MIRT2047667	hsa-miR-1226	CLIP-seq
MIRT2047668	hsa-miR-1229	CLIP-seq
MIRT2047669	hsa-miR-1269	CLIP-seq
MIRT2047670	hsa-miR-1269b	CLIP-seq
MIRT2047671	hsa-miR-1273	CLIP-seq
MIRT2047672	hsa-miR-1279	CLIP-seq
MIRT1164935	hsa-miR-129-5p	CLIP-seq
MIRT2047673	hsa-miR-1297	CLIP-seq
MIRT1164936	hsa-miR-1298	CLIP-seq
MIRT2047674	hsa-miR-1301	CLIP-seq
MIRT2047675	hsa-miR-1304	CLIP-seq
MIRT1164937	hsa-miR-1324	CLIP-seq
MIRT2047676	hsa-miR-140-3p	CLIP-seq
MIRT2047677	hsa-miR-145	CLIP-seq
MIRT1164940	hsa-miR-15a	CLIP-seq
MIRT1164941	hsa-miR-15b	CLIP-seq
MIRT1164942	hsa-miR-16	CLIP-seq
MIRT1164943	hsa-miR-1827	CLIP-seq
MIRT2047678	hsa-miR-1908	CLIP-seq
MIRT1164944	hsa-miR-195	CLIP-seq
MIRT1164946	hsa-miR-19a	CLIP-seq
MIRT1164947	hsa-miR-19b	CLIP-seq
MIRT1164953	hsa-miR-205	CLIP-seq
MIRT1164954	hsa-miR-2114	CLIP-seq
MIRT1164955	hsa-miR-2115	CLIP-seq
MIRT1164956	hsa-miR-214	CLIP-seq
MIRT2047679	hsa-miR-221	CLIP-seq
MIRT2047680	hsa-miR-222	CLIP-seq
MIRT1164957	hsa-miR-2276	CLIP-seq
MIRT2047681	hsa-miR-26a	CLIP-seq
MIRT2047682	hsa-miR-26b	CLIP-seq
MIRT2047683	hsa-miR-299-5p	CLIP-seq
MIRT2047684	hsa-miR-29a	CLIP-seq
MIRT2047685	hsa-miR-29b	CLIP-seq
MIRT2047686	hsa-miR-29c	CLIP-seq
MIRT1164967	hsa-miR-3120-3p	CLIP-seq
MIRT2047687	hsa-miR-3122	CLIP-seq
MIRT1164970	hsa-miR-3127-5p	CLIP-seq
MIRT1164974	hsa-miR-3149	CLIP-seq
MIRT1164977	hsa-miR-3155	CLIP-seq
MIRT1164978	hsa-miR-3155b	CLIP-seq
MIRT1164980	hsa-miR-3158-3p	CLIP-seq
MIRT2047688	hsa-miR-3163	CLIP-seq
MIRT1164983	hsa-miR-3180-5p	CLIP-seq
MIRT2047689	hsa-miR-338-3p	CLIP-seq
MIRT2047690	hsa-miR-339-3p	CLIP-seq
MIRT2047691	hsa-miR-340	CLIP-seq
MIRT1164992	hsa-miR-3612	CLIP-seq
MIRT2047692	hsa-miR-361-5p	CLIP-seq
MIRT1164994	hsa-miR-3617	CLIP-seq
MIRT1164995	hsa-miR-3619-5p	CLIP-seq
MIRT2047693	hsa-miR-3657	CLIP-seq
MIRT2047694	hsa-miR-3662	CLIP-seq
MIRT1165000	hsa-miR-3664-5p	CLIP-seq
MIRT2047695	hsa-miR-3667-3p	CLIP-seq
MIRT2047696	hsa-miR-3677-5p	CLIP-seq
MIRT1165001	hsa-miR-3689a-3p	CLIP-seq
MIRT1165002	hsa-miR-3689c	CLIP-seq
MIRT2047697	hsa-miR-3913-5p	CLIP-seq
MIRT1165013	hsa-miR-3914	CLIP-seq
MIRT1165016	hsa-miR-3929	CLIP-seq
MIRT2047698	hsa-miR-3944-5p	CLIP-seq
MIRT1165019	hsa-miR-424	CLIP-seq
MIRT2047699	hsa-miR-4266	CLIP-seq
MIRT2047700	hsa-miR-4272	CLIP-seq
MIRT1165025	hsa-miR-4274	CLIP-seq
MIRT1165028	hsa-miR-4284	CLIP-seq
MIRT1165030	hsa-miR-4291	CLIP-seq
MIRT2047701	hsa-miR-4310	CLIP-seq
MIRT2047702	hsa-miR-432	CLIP-seq
MIRT1165038	hsa-miR-4419b	CLIP-seq
MIRT2047703	hsa-miR-4421	CLIP-seq
MIRT1165039	hsa-miR-4427	CLIP-seq
MIRT1165040	hsa-miR-4436b-5p	CLIP-seq
MIRT1165041	hsa-miR-4443	CLIP-seq
MIRT1165042	hsa-miR-4446-3p	CLIP-seq
MIRT1165045	hsa-miR-4459	CLIP-seq
MIRT2047704	hsa-miR-4465	CLIP-seq
MIRT1165048	hsa-miR-4478	CLIP-seq
MIRT2047705	hsa-miR-4486	CLIP-seq
MIRT2047706	hsa-miR-4494	CLIP-seq
MIRT2047707	hsa-miR-4519	CLIP-seq
MIRT2047708	hsa-miR-4529-3p	CLIP-seq
MIRT1165059	hsa-miR-4649-3p	CLIP-seq
MIRT2047709	hsa-miR-4649-5p	CLIP-seq
MIRT1165062	hsa-miR-4659a-3p	CLIP-seq
MIRT1165064	hsa-miR-4659b-3p	CLIP-seq
MIRT2047710	hsa-miR-4660	CLIP-seq
MIRT2047711	hsa-miR-4668-3p	CLIP-seq
MIRT2047712	hsa-miR-4684-5p	CLIP-seq
MIRT2047713	hsa-miR-4691-5p	CLIP-seq
MIRT2047714	hsa-miR-4696	CLIP-seq
MIRT2047715	hsa-miR-4698	CLIP-seq
MIRT1165073	hsa-miR-4714-5p	CLIP-seq
MIRT1165076	hsa-miR-4722-5p	CLIP-seq
MIRT1165077	hsa-miR-4724-3p	CLIP-seq
MIRT1165078	hsa-miR-4724-5p	CLIP-seq
MIRT1165079	hsa-miR-4728-5p	CLIP-seq
MIRT2047716	hsa-miR-4729	CLIP-seq
MIRT2047717	hsa-miR-4733-3p	CLIP-seq
MIRT1165082	hsa-miR-4762-3p	CLIP-seq
MIRT1165083	hsa-miR-4763-3p	CLIP-seq
MIRT1165084	hsa-miR-4768-3p	CLIP-seq
MIRT2047718	hsa-miR-4772-3p	CLIP-seq
MIRT2047719	hsa-miR-4775	CLIP-seq
MIRT2047720	hsa-miR-4793-3p	CLIP-seq
MIRT1165090	hsa-miR-4802-3p	CLIP-seq
MIRT1165091	hsa-miR-485-5p	CLIP-seq
MIRT1165094	hsa-miR-497	CLIP-seq
MIRT2047721	hsa-miR-499a-5p	CLIP-seq
MIRT1165095	hsa-miR-500a	CLIP-seq
MIRT2047722	hsa-miR-5047	CLIP-seq
MIRT2047723	hsa-miR-508-5p	CLIP-seq
MIRT2047724	hsa-miR-5096	CLIP-seq
MIRT2047725	hsa-miR-513a-5p	CLIP-seq
MIRT1165104	hsa-miR-516b	CLIP-seq
MIRT1165105	hsa-miR-520a-5p	CLIP-seq
MIRT1165106	hsa-miR-525-5p	CLIP-seq
MIRT2047726	hsa-miR-532-5p	CLIP-seq
MIRT2047727	hsa-miR-539	CLIP-seq
MIRT1165108	hsa-miR-541	CLIP-seq
MIRT2047728	hsa-miR-544	CLIP-seq
MIRT2047729	hsa-miR-548v	CLIP-seq
MIRT2047730	hsa-miR-552	CLIP-seq
MIRT2047731	hsa-miR-590-3p	CLIP-seq
MIRT2047732	hsa-miR-617	CLIP-seq
MIRT1165124	hsa-miR-641	CLIP-seq
MIRT1165125	hsa-miR-650	CLIP-seq
MIRT1165127	hsa-miR-654-5p	CLIP-seq
MIRT2047733	hsa-miR-659	CLIP-seq
MIRT2047734	hsa-miR-660	CLIP-seq
MIRT2047735	hsa-miR-661	CLIP-seq
MIRT2047736	hsa-miR-663	CLIP-seq
MIRT1165131	hsa-miR-761	CLIP-seq
MIRT2047737	hsa-miR-766	CLIP-seq
MIRT2047738	hsa-miR-767-5p	CLIP-seq
MIRT2047739	hsa-miR-873	CLIP-seq
MIRT1165137	hsa-miR-935	CLIP-seq
MIRT1165138	hsa-miR-940	CLIP-seq
MIRT2047740	hsa-miR-942	CLIP-seq
MIRT1164920	hsa-miR-103b	CLIP-seq
MIRT1164921	hsa-miR-1184	CLIP-seq
MIRT1164923	hsa-miR-1207-5p	CLIP-seq
MIRT2047668	hsa-miR-1229	CLIP-seq
MIRT1164926	hsa-miR-1255a	CLIP-seq
MIRT1164927	hsa-miR-1255b	CLIP-seq
MIRT2047669	hsa-miR-1269	CLIP-seq
MIRT2047670	hsa-miR-1269b	CLIP-seq
MIRT2276485	hsa-miR-1270	CLIP-seq
MIRT2047671	hsa-miR-1273	CLIP-seq
MIRT2276486	hsa-miR-1273f	CLIP-seq
MIRT2047672	hsa-miR-1279	CLIP-seq
MIRT2276487	hsa-miR-128	CLIP-seq
MIRT1164935	hsa-miR-129-5p	CLIP-seq
MIRT2047673	hsa-miR-1297	CLIP-seq
MIRT1164936	hsa-miR-1298	CLIP-seq
MIRT2276488	hsa-miR-1321	CLIP-seq
MIRT1164937	hsa-miR-1324	CLIP-seq
MIRT2047676	hsa-miR-140-3p	CLIP-seq
MIRT2276489	hsa-miR-146a	CLIP-seq
MIRT2276490	hsa-miR-146b-5p	CLIP-seq
MIRT1164940	hsa-miR-15a	CLIP-seq
MIRT1164941	hsa-miR-15b	CLIP-seq
MIRT1164942	hsa-miR-16	CLIP-seq
MIRT1164943	hsa-miR-1827	CLIP-seq
MIRT2047678	hsa-miR-1908	CLIP-seq
MIRT1164944	hsa-miR-195	CLIP-seq
MIRT1164946	hsa-miR-19a	CLIP-seq
MIRT1164947	hsa-miR-19b	CLIP-seq
MIRT1164952	hsa-miR-203	CLIP-seq
MIRT1164953	hsa-miR-205	CLIP-seq
MIRT1164954	hsa-miR-2114	CLIP-seq
MIRT1164955	hsa-miR-2115	CLIP-seq
MIRT1164957	hsa-miR-2276	CLIP-seq
MIRT2047681	hsa-miR-26a	CLIP-seq
MIRT2047682	hsa-miR-26b	CLIP-seq
MIRT2276491	hsa-miR-28-3p	CLIP-seq
MIRT2276492	hsa-miR-3074-3p	CLIP-seq
MIRT1164961	hsa-miR-30a	CLIP-seq
MIRT1164962	hsa-miR-30b	CLIP-seq
MIRT1164963	hsa-miR-30c	CLIP-seq
MIRT1164964	hsa-miR-30d	CLIP-seq
MIRT1164965	hsa-miR-30e	CLIP-seq
MIRT2276493	hsa-miR-31	CLIP-seq
MIRT2276494	hsa-miR-3117-5p	CLIP-seq
MIRT1164967	hsa-miR-3120-3p	CLIP-seq
MIRT2276495	hsa-miR-3121-3p	CLIP-seq
MIRT2047687	hsa-miR-3122	CLIP-seq
MIRT1164968	hsa-miR-3124-3p	CLIP-seq
MIRT1164970	hsa-miR-3127-5p	CLIP-seq
MIRT1164972	hsa-miR-3140-5p	CLIP-seq
MIRT1164974	hsa-miR-3149	CLIP-seq
MIRT2276496	hsa-miR-3157-5p	CLIP-seq
MIRT1164980	hsa-miR-3158-3p	CLIP-seq
MIRT2276497	hsa-miR-3160-5p	CLIP-seq
MIRT2276498	hsa-miR-3162-5p	CLIP-seq
MIRT1164982	hsa-miR-3170	CLIP-seq
MIRT1164983	hsa-miR-3180-5p	CLIP-seq
MIRT2276499	hsa-miR-324-5p	CLIP-seq
MIRT2047689	hsa-miR-338-3p	CLIP-seq
MIRT1164990	hsa-miR-34c-3p	CLIP-seq
MIRT2276500	hsa-miR-3607-3p	CLIP-seq
MIRT1164992	hsa-miR-3612	CLIP-seq
MIRT2276501	hsa-miR-3613-3p	CLIP-seq
MIRT1164993	hsa-miR-3614-5p	CLIP-seq
MIRT2047692	hsa-miR-361-5p	CLIP-seq
MIRT1164994	hsa-miR-3617	CLIP-seq
MIRT2276502	hsa-miR-3622a-3p	CLIP-seq
MIRT2276503	hsa-miR-3622b-3p	CLIP-seq
MIRT1164996	hsa-miR-3622b-5p	CLIP-seq
MIRT2047693	hsa-miR-3657	CLIP-seq
MIRT1164999	hsa-miR-3663-3p	CLIP-seq
MIRT1165000	hsa-miR-3664-5p	CLIP-seq
MIRT2047695	hsa-miR-3667-3p	CLIP-seq
MIRT2276504	hsa-miR-3686	CLIP-seq
MIRT1165001	hsa-miR-3689a-3p	CLIP-seq
MIRT1165002	hsa-miR-3689c	CLIP-seq
MIRT1165005	hsa-miR-370	CLIP-seq
MIRT1165007	hsa-miR-371-5p	CLIP-seq
MIRT2047697	hsa-miR-3913-5p	CLIP-seq
MIRT1165013	hsa-miR-3914	CLIP-seq
MIRT2276505	hsa-miR-3925-5p	CLIP-seq
MIRT1165015	hsa-miR-3928	CLIP-seq
MIRT1165016	hsa-miR-3929	CLIP-seq
MIRT2276506	hsa-miR-3936	CLIP-seq
MIRT1165019	hsa-miR-424	CLIP-seq
MIRT1165020	hsa-miR-4251	CLIP-seq
MIRT1165025	hsa-miR-4274	CLIP-seq
MIRT1165030	hsa-miR-4291	CLIP-seq
MIRT2047701	hsa-miR-4310	CLIP-seq
MIRT2276507	hsa-miR-4315	CLIP-seq
MIRT2047702	hsa-miR-432	CLIP-seq
MIRT1165036	hsa-miR-4418	CLIP-seq
MIRT1165038	hsa-miR-4419b	CLIP-seq
MIRT2047703	hsa-miR-4421	CLIP-seq
MIRT1165039	hsa-miR-4427	CLIP-seq
MIRT1165041	hsa-miR-4443	CLIP-seq
MIRT1165042	hsa-miR-4446-3p	CLIP-seq
MIRT1165043	hsa-miR-4455	CLIP-seq
MIRT1165045	hsa-miR-4459	CLIP-seq
MIRT2047704	hsa-miR-4465	CLIP-seq
MIRT2276508	hsa-miR-4475	CLIP-seq
MIRT1165048	hsa-miR-4478	CLIP-seq
MIRT2047705	hsa-miR-4486	CLIP-seq
MIRT1165054	hsa-miR-451b	CLIP-seq
MIRT2276509	hsa-miR-4521	CLIP-seq
MIRT2047708	hsa-miR-4529-3p	CLIP-seq
MIRT2276510	hsa-miR-4531	CLIP-seq
MIRT1165056	hsa-miR-4642	CLIP-seq
MIRT1165059	hsa-miR-4649-3p	CLIP-seq
MIRT2047709	hsa-miR-4649-5p	CLIP-seq
MIRT1165060	hsa-miR-4651	CLIP-seq
MIRT1165061	hsa-miR-4655-5p	CLIP-seq
MIRT2276511	hsa-miR-4662a-5p	CLIP-seq
MIRT2276512	hsa-miR-4670-3p	CLIP-seq
MIRT2276513	hsa-miR-4675	CLIP-seq
MIRT2276514	hsa-miR-4677-5p	CLIP-seq
MIRT2276515	hsa-miR-4683	CLIP-seq
MIRT2047712	hsa-miR-4684-5p	CLIP-seq
MIRT2276516	hsa-miR-4691-3p	CLIP-seq
MIRT2047713	hsa-miR-4691-5p	CLIP-seq
MIRT2276517	hsa-miR-4693-3p	CLIP-seq
MIRT2276518	hsa-miR-4694-5p	CLIP-seq
MIRT1165070	hsa-miR-4695-5p	CLIP-seq
MIRT1165073	hsa-miR-4714-5p	CLIP-seq
MIRT1165074	hsa-miR-4717-3p	CLIP-seq
MIRT1165076	hsa-miR-4722-5p	CLIP-seq
MIRT1165078	hsa-miR-4724-5p	CLIP-seq
MIRT1165079	hsa-miR-4728-5p	CLIP-seq
MIRT2047716	hsa-miR-4729	CLIP-seq
MIRT2276519	hsa-miR-4739	CLIP-seq
MIRT2276520	hsa-miR-4741	CLIP-seq
MIRT2276521	hsa-miR-4756-5p	CLIP-seq
MIRT1165083	hsa-miR-4763-3p	CLIP-seq
MIRT1165084	hsa-miR-4768-3p	CLIP-seq
MIRT1165086	hsa-miR-4773	CLIP-seq
MIRT2047720	hsa-miR-4793-3p	CLIP-seq
MIRT2276522	hsa-miR-4797-5p	CLIP-seq
MIRT1165090	hsa-miR-4802-3p	CLIP-seq
MIRT1165091	hsa-miR-485-5p	CLIP-seq
MIRT1165092	hsa-miR-487a	CLIP-seq
MIRT1165094	hsa-miR-497	CLIP-seq
MIRT2047723	hsa-miR-508-5p	CLIP-seq
MIRT1165099	hsa-miR-509-3-5p	CLIP-seq
MIRT1165100	hsa-miR-509-5p	CLIP-seq
MIRT2047725	hsa-miR-513a-5p	CLIP-seq
MIRT1165104	hsa-miR-516b	CLIP-seq
MIRT1165105	hsa-miR-520a-5p	CLIP-seq
MIRT1165106	hsa-miR-525-5p	CLIP-seq
MIRT2047727	hsa-miR-539	CLIP-seq
MIRT1165108	hsa-miR-541	CLIP-seq
MIRT2276523	hsa-miR-545	CLIP-seq
MIRT1165109	hsa-miR-548a-3p	CLIP-seq
MIRT2276524	hsa-miR-548aa	CLIP-seq
MIRT2276525	hsa-miR-548ac	CLIP-seq
MIRT1165110	hsa-miR-548ae	CLIP-seq
MIRT2276526	hsa-miR-548ag	CLIP-seq
MIRT2276527	hsa-miR-548ai	CLIP-seq
MIRT1165111	hsa-miR-548aj	CLIP-seq
MIRT1165112	hsa-miR-548am	CLIP-seq
MIRT2276528	hsa-miR-548d-3p	CLIP-seq
MIRT1165114	hsa-miR-548e	CLIP-seq
MIRT1165115	hsa-miR-548f	CLIP-seq
MIRT2276529	hsa-miR-548m	CLIP-seq
MIRT1165118	hsa-miR-548x	CLIP-seq
MIRT2276530	hsa-miR-548z	CLIP-seq
MIRT2276531	hsa-miR-556-5p	CLIP-seq
MIRT1165120	hsa-miR-577	CLIP-seq
MIRT2276532	hsa-miR-589	CLIP-seq
MIRT2276533	hsa-miR-593	CLIP-seq
MIRT2276534	hsa-miR-595	CLIP-seq
MIRT1165121	hsa-miR-608	CLIP-seq
MIRT2047732	hsa-miR-617	CLIP-seq
MIRT2276535	hsa-miR-620	CLIP-seq
MIRT1165123	hsa-miR-635	CLIP-seq
MIRT1165124	hsa-miR-641	CLIP-seq
MIRT1165125	hsa-miR-650	CLIP-seq
MIRT1165127	hsa-miR-654-5p	CLIP-seq
MIRT2047735	hsa-miR-661	CLIP-seq
MIRT2047736	hsa-miR-663	CLIP-seq
MIRT1165129	hsa-miR-665	CLIP-seq
MIRT2276536	hsa-miR-759	CLIP-seq
MIRT2047737	hsa-miR-766	CLIP-seq
MIRT1165132	hsa-miR-767-3p	CLIP-seq
MIRT2047738	hsa-miR-767-5p	CLIP-seq
MIRT2047739	hsa-miR-873	CLIP-seq
MIRT2276537	hsa-miR-9	CLIP-seq
MIRT1165138	hsa-miR-940	CLIP-seq
MIRT2047740	hsa-miR-942	CLIP-seq
MIRT2047669	hsa-miR-1269	CLIP-seq
MIRT2047670	hsa-miR-1269b	CLIP-seq
MIRT2391172	hsa-miR-1273e	CLIP-seq
MIRT2047674	hsa-miR-1301	CLIP-seq
MIRT1164943	hsa-miR-1827	CLIP-seq
MIRT1164946	hsa-miR-19a	CLIP-seq
MIRT1164947	hsa-miR-19b	CLIP-seq
MIRT1164954	hsa-miR-2114	CLIP-seq
MIRT2047687	hsa-miR-3122	CLIP-seq
MIRT1164983	hsa-miR-3180-5p	CLIP-seq
MIRT2047689	hsa-miR-338-3p	CLIP-seq
MIRT1164992	hsa-miR-3612	CLIP-seq
MIRT1164996	hsa-miR-3622b-5p	CLIP-seq
MIRT1165000	hsa-miR-3664-5p	CLIP-seq
MIRT1165001	hsa-miR-3689a-3p	CLIP-seq
MIRT1165002	hsa-miR-3689c	CLIP-seq
MIRT2047697	hsa-miR-3913-5p	CLIP-seq
MIRT1165016	hsa-miR-3929	CLIP-seq
MIRT2047698	hsa-miR-3944-5p	CLIP-seq
MIRT2391173	hsa-miR-4287	CLIP-seq
MIRT2047701	hsa-miR-4310	CLIP-seq
MIRT2047702	hsa-miR-432	CLIP-seq
MIRT1165038	hsa-miR-4419b	CLIP-seq
MIRT1165041	hsa-miR-4443	CLIP-seq
MIRT1165045	hsa-miR-4459	CLIP-seq
MIRT1165048	hsa-miR-4478	CLIP-seq
MIRT2047708	hsa-miR-4529-3p	CLIP-seq
MIRT1165059	hsa-miR-4649-3p	CLIP-seq
MIRT2047710	hsa-miR-4660	CLIP-seq
MIRT2276515	hsa-miR-4683	CLIP-seq
MIRT2391174	hsa-miR-4685-3p	CLIP-seq
MIRT2047713	hsa-miR-4691-5p	CLIP-seq
MIRT1165073	hsa-miR-4714-5p	CLIP-seq
MIRT1165076	hsa-miR-4722-5p	CLIP-seq
MIRT1165079	hsa-miR-4728-5p	CLIP-seq
MIRT1165084	hsa-miR-4768-3p	CLIP-seq
MIRT2391175	hsa-miR-4793-5p	CLIP-seq
MIRT1165091	hsa-miR-485-5p	CLIP-seq
MIRT1165096	hsa-miR-501-3p	CLIP-seq
MIRT1165097	hsa-miR-502-3p	CLIP-seq
MIRT2047722	hsa-miR-5047	CLIP-seq
MIRT1165104	hsa-miR-516b	CLIP-seq
MIRT1165105	hsa-miR-520a-5p	CLIP-seq
MIRT1165106	hsa-miR-525-5p	CLIP-seq
MIRT1165108	hsa-miR-541	CLIP-seq
MIRT2047732	hsa-miR-617	CLIP-seq
MIRT1165125	hsa-miR-650	CLIP-seq
MIRT1165127	hsa-miR-654-5p	CLIP-seq
MIRT1165129	hsa-miR-665	CLIP-seq
MIRT2047738	hsa-miR-767-5p	CLIP-seq
MIRT1165138	hsa-miR-940	CLIP-seq
MIRT2431289	hsa-miR-2909	CLIP-seq
MIRT2431290	hsa-miR-3064-5p	CLIP-seq
MIRT2431291	hsa-miR-3682-5p	CLIP-seq
MIRT2431292	hsa-miR-4278	CLIP-seq
MIRT2431293	hsa-miR-4682	CLIP-seq
MIRT2431294	hsa-miR-892b	CLIP-seq
MIRT1164924	hsa-miR-1224-3p	CLIP-seq
MIRT2047667	hsa-miR-1226	CLIP-seq
MIRT1164928	hsa-miR-1260	CLIP-seq
MIRT1164929	hsa-miR-1260b	CLIP-seq
MIRT1164931	hsa-miR-1280	CLIP-seq
MIRT2047683	hsa-miR-299-5p	CLIP-seq
MIRT2047687	hsa-miR-3122	CLIP-seq
MIRT1164972	hsa-miR-3140-5p	CLIP-seq
MIRT2047689	hsa-miR-338-3p	CLIP-seq
MIRT1164998	hsa-miR-3647-3p	CLIP-seq
MIRT1165001	hsa-miR-3689a-3p	CLIP-seq
MIRT1165002	hsa-miR-3689c	CLIP-seq
MIRT2047697	hsa-miR-3913-5p	CLIP-seq
MIRT1165016	hsa-miR-3929	CLIP-seq
MIRT2047701	hsa-miR-4310	CLIP-seq
MIRT1165038	hsa-miR-4419b	CLIP-seq
MIRT1165039	hsa-miR-4427	CLIP-seq
MIRT2454581	hsa-miR-4438	CLIP-seq
MIRT1165048	hsa-miR-4478	CLIP-seq
MIRT1165079	hsa-miR-4728-5p	CLIP-seq
MIRT2047717	hsa-miR-4733-3p	CLIP-seq
MIRT1165091	hsa-miR-485-5p	CLIP-seq
MIRT1165096	hsa-miR-501-3p	CLIP-seq
MIRT1165097	hsa-miR-502-3p	CLIP-seq
MIRT2454582	hsa-miR-5095	CLIP-seq
MIRT1165107	hsa-miR-532-3p	CLIP-seq
MIRT1165108	hsa-miR-541	CLIP-seq
MIRT2454583	hsa-miR-629	CLIP-seq
MIRT1165127	hsa-miR-654-5p	CLIP-seq
MIRT2047667	hsa-miR-1226	CLIP-seq
MIRT1164998	hsa-miR-3647-3p	CLIP-seq
MIRT2047717	hsa-miR-4733-3p	CLIP-seq
MIRT1165096	hsa-miR-501-3p	CLIP-seq
MIRT1165097	hsa-miR-502-3p	CLIP-seq
MIRT1164921	hsa-miR-1184	CLIP-seq
MIRT2575360	hsa-miR-1205	CLIP-seq
MIRT1164924	hsa-miR-1224-3p	CLIP-seq
MIRT2047667	hsa-miR-1226	CLIP-seq
MIRT1164928	hsa-miR-1260	CLIP-seq
MIRT1164929	hsa-miR-1260b	CLIP-seq
MIRT2047669	hsa-miR-1269	CLIP-seq
MIRT2047670	hsa-miR-1269b	CLIP-seq
MIRT2047671	hsa-miR-1273	CLIP-seq
MIRT2047672	hsa-miR-1279	CLIP-seq
MIRT2276487	hsa-miR-128	CLIP-seq
MIRT1164931	hsa-miR-1280	CLIP-seq
MIRT2575361	hsa-miR-1287	CLIP-seq
MIRT2575362	hsa-miR-129-3p	CLIP-seq
MIRT1164935	hsa-miR-129-5p	CLIP-seq
MIRT2276489	hsa-miR-146a	CLIP-seq
MIRT2276490	hsa-miR-146b-5p	CLIP-seq
MIRT1164943	hsa-miR-1827	CLIP-seq
MIRT2575363	hsa-miR-18a	CLIP-seq
MIRT2575364	hsa-miR-18b	CLIP-seq
MIRT2047678	hsa-miR-1908	CLIP-seq
MIRT1164953	hsa-miR-205	CLIP-seq
MIRT1164954	hsa-miR-2114	CLIP-seq
MIRT2047683	hsa-miR-299-5p	CLIP-seq
MIRT2276494	hsa-miR-3117-5p	CLIP-seq
MIRT2047687	hsa-miR-3122	CLIP-seq
MIRT2575365	hsa-miR-3135b	CLIP-seq
MIRT1164971	hsa-miR-3140-3p	CLIP-seq
MIRT1164972	hsa-miR-3140-5p	CLIP-seq
MIRT2575366	hsa-miR-3143	CLIP-seq
MIRT1164974	hsa-miR-3149	CLIP-seq
MIRT2575367	hsa-miR-3158-5p	CLIP-seq
MIRT2575368	hsa-miR-3177-3p	CLIP-seq
MIRT1164983	hsa-miR-3180-5p	CLIP-seq
MIRT2047689	hsa-miR-338-3p	CLIP-seq
MIRT2047690	hsa-miR-339-3p	CLIP-seq
MIRT1164992	hsa-miR-3612	CLIP-seq
MIRT2276501	hsa-miR-3613-3p	CLIP-seq
MIRT2047693	hsa-miR-3657	CLIP-seq
MIRT1165000	hsa-miR-3664-5p	CLIP-seq
MIRT2047696	hsa-miR-3677-5p	CLIP-seq
MIRT1165001	hsa-miR-3689a-3p	CLIP-seq
MIRT1165002	hsa-miR-3689c	CLIP-seq
MIRT2047697	hsa-miR-3913-5p	CLIP-seq
MIRT2276505	hsa-miR-3925-5p	CLIP-seq
MIRT1165016	hsa-miR-3929	CLIP-seq
MIRT2575369	hsa-miR-3941	CLIP-seq
MIRT2575370	hsa-miR-3974	CLIP-seq
MIRT1165020	hsa-miR-4251	CLIP-seq
MIRT2575371	hsa-miR-4282	CLIP-seq
MIRT1165032	hsa-miR-431	CLIP-seq
MIRT2047701	hsa-miR-4310	CLIP-seq
MIRT2047702	hsa-miR-432	CLIP-seq
MIRT1165038	hsa-miR-4419b	CLIP-seq
MIRT2047703	hsa-miR-4421	CLIP-seq
MIRT1165039	hsa-miR-4427	CLIP-seq
MIRT2454581	hsa-miR-4438	CLIP-seq
MIRT1165041	hsa-miR-4443	CLIP-seq
MIRT1165043	hsa-miR-4455	CLIP-seq
MIRT1165048	hsa-miR-4478	CLIP-seq
MIRT2047705	hsa-miR-4486	CLIP-seq
MIRT2575372	hsa-miR-450b-5p	CLIP-seq
MIRT2047707	hsa-miR-4519	CLIP-seq
MIRT1165054	hsa-miR-451b	CLIP-seq
MIRT2047708	hsa-miR-4529-3p	CLIP-seq
MIRT2575373	hsa-miR-4540	CLIP-seq
MIRT2575374	hsa-miR-4638-3p	CLIP-seq
MIRT1165057	hsa-miR-4643	CLIP-seq
MIRT1165059	hsa-miR-4649-3p	CLIP-seq
MIRT2047709	hsa-miR-4649-5p	CLIP-seq
MIRT1165066	hsa-miR-466	CLIP-seq
MIRT2575375	hsa-miR-4671-5p	CLIP-seq
MIRT2575376	hsa-miR-4672	CLIP-seq
MIRT2047712	hsa-miR-4684-5p	CLIP-seq
MIRT2047713	hsa-miR-4691-5p	CLIP-seq
MIRT2047714	hsa-miR-4696	CLIP-seq
MIRT2575377	hsa-miR-4701-5p	CLIP-seq
MIRT1165073	hsa-miR-4714-5p	CLIP-seq
MIRT1165076	hsa-miR-4722-5p	CLIP-seq
MIRT1165079	hsa-miR-4728-5p	CLIP-seq
MIRT2047717	hsa-miR-4733-3p	CLIP-seq
MIRT2575378	hsa-miR-4735-3p	CLIP-seq
MIRT1165084	hsa-miR-4768-3p	CLIP-seq
MIRT1165086	hsa-miR-4773	CLIP-seq
MIRT2575379	hsa-miR-4776-3p	CLIP-seq
MIRT1165089	hsa-miR-4789-3p	CLIP-seq
MIRT2047720	hsa-miR-4793-3p	CLIP-seq
MIRT2575380	hsa-miR-4803	CLIP-seq
MIRT1165091	hsa-miR-485-5p	CLIP-seq
MIRT1165096	hsa-miR-501-3p	CLIP-seq
MIRT1165097	hsa-miR-502-3p	CLIP-seq
MIRT2575381	hsa-miR-505	CLIP-seq
MIRT2575382	hsa-miR-507	CLIP-seq
MIRT2047723	hsa-miR-508-5p	CLIP-seq
MIRT2454582	hsa-miR-5095	CLIP-seq
MIRT2575383	hsa-miR-513a-3p	CLIP-seq
MIRT1165104	hsa-miR-516b	CLIP-seq
MIRT2575384	hsa-miR-518a-5p	CLIP-seq
MIRT1165105	hsa-miR-520a-5p	CLIP-seq
MIRT1165106	hsa-miR-525-5p	CLIP-seq
MIRT2575385	hsa-miR-527	CLIP-seq
MIRT1165107	hsa-miR-532-3p	CLIP-seq
MIRT2047726	hsa-miR-532-5p	CLIP-seq
MIRT1165108	hsa-miR-541	CLIP-seq
MIRT2047728	hsa-miR-544	CLIP-seq
MIRT1165109	hsa-miR-548a-3p	CLIP-seq
MIRT2575386	hsa-miR-548a-5p	CLIP-seq
MIRT2575387	hsa-miR-548ab	CLIP-seq
MIRT2276525	hsa-miR-548ac	CLIP-seq
MIRT2575388	hsa-miR-548ad	CLIP-seq
MIRT1165110	hsa-miR-548ae	CLIP-seq
MIRT1165111	hsa-miR-548aj	CLIP-seq
MIRT2575389	hsa-miR-548ak	CLIP-seq
MIRT1165112	hsa-miR-548am	CLIP-seq
MIRT2575390	hsa-miR-548b-5p	CLIP-seq
MIRT2575391	hsa-miR-548c-5p	CLIP-seq
MIRT2276528	hsa-miR-548d-3p	CLIP-seq
MIRT2575392	hsa-miR-548d-5p	CLIP-seq
MIRT1165114	hsa-miR-548e	CLIP-seq
MIRT1165115	hsa-miR-548f	CLIP-seq
MIRT2575393	hsa-miR-548h	CLIP-seq
MIRT2575394	hsa-miR-548i	CLIP-seq
MIRT2575395	hsa-miR-548j	CLIP-seq
MIRT2575396	hsa-miR-548w	CLIP-seq
MIRT1165118	hsa-miR-548x	CLIP-seq
MIRT2575397	hsa-miR-548y	CLIP-seq
MIRT2276530	hsa-miR-548z	CLIP-seq
MIRT2047730	hsa-miR-552	CLIP-seq
MIRT2575398	hsa-miR-557	CLIP-seq
MIRT2575399	hsa-miR-559	CLIP-seq
MIRT2575400	hsa-miR-571	CLIP-seq
MIRT2575401	hsa-miR-588	CLIP-seq
MIRT2276532	hsa-miR-589	CLIP-seq
MIRT2276533	hsa-miR-593	CLIP-seq
MIRT2047732	hsa-miR-617	CLIP-seq
MIRT2454583	hsa-miR-629	CLIP-seq
MIRT1165125	hsa-miR-650	CLIP-seq
MIRT1165127	hsa-miR-654-5p	CLIP-seq
MIRT2047735	hsa-miR-661	CLIP-seq
MIRT2047736	hsa-miR-663	CLIP-seq
MIRT2575402	hsa-miR-671-5p	CLIP-seq
MIRT2047737	hsa-miR-766	CLIP-seq
MIRT1165132	hsa-miR-767-3p	CLIP-seq
MIRT2047738	hsa-miR-767-5p	CLIP-seq
MIRT2575403	hsa-miR-938	CLIP-seq
MIRT1165138	hsa-miR-940	CLIP-seq
MIRT1164921	hsa-miR-1184	CLIP-seq
MIRT2575360	hsa-miR-1205	CLIP-seq
MIRT1164924	hsa-miR-1224-3p	CLIP-seq
MIRT2047667	hsa-miR-1226	CLIP-seq
MIRT1164928	hsa-miR-1260	CLIP-seq
MIRT1164929	hsa-miR-1260b	CLIP-seq
MIRT2047672	hsa-miR-1279	CLIP-seq
MIRT2276487	hsa-miR-128	CLIP-seq
MIRT1164931	hsa-miR-1280	CLIP-seq
MIRT2575361	hsa-miR-1287	CLIP-seq
MIRT1164935	hsa-miR-129-5p	CLIP-seq
MIRT2276489	hsa-miR-146a	CLIP-seq
MIRT2276490	hsa-miR-146b-5p	CLIP-seq
MIRT1164953	hsa-miR-205	CLIP-seq
MIRT1164954	hsa-miR-2114	CLIP-seq
MIRT1164957	hsa-miR-2276	CLIP-seq
MIRT2047683	hsa-miR-299-5p	CLIP-seq
MIRT2276494	hsa-miR-3117-5p	CLIP-seq
MIRT2047687	hsa-miR-3122	CLIP-seq
MIRT2575365	hsa-miR-3135b	CLIP-seq
MIRT1164971	hsa-miR-3140-3p	CLIP-seq
MIRT1164972	hsa-miR-3140-5p	CLIP-seq
MIRT1164974	hsa-miR-3149	CLIP-seq
MIRT2575367	hsa-miR-3158-5p	CLIP-seq
MIRT2047689	hsa-miR-338-3p	CLIP-seq
MIRT2047690	hsa-miR-339-3p	CLIP-seq
MIRT1164992	hsa-miR-3612	CLIP-seq
MIRT2047693	hsa-miR-3657	CLIP-seq
MIRT1165000	hsa-miR-3664-5p	CLIP-seq
MIRT2047696	hsa-miR-3677-5p	CLIP-seq
MIRT1165001	hsa-miR-3689a-3p	CLIP-seq
MIRT1165002	hsa-miR-3689c	CLIP-seq
MIRT2047697	hsa-miR-3913-5p	CLIP-seq
MIRT1165016	hsa-miR-3929	CLIP-seq
MIRT2575369	hsa-miR-3941	CLIP-seq
MIRT2575370	hsa-miR-3974	CLIP-seq
MIRT1165020	hsa-miR-4251	CLIP-seq
MIRT1165032	hsa-miR-431	CLIP-seq
MIRT2047701	hsa-miR-4310	CLIP-seq
MIRT1165038	hsa-miR-4419b	CLIP-seq
MIRT2047703	hsa-miR-4421	CLIP-seq
MIRT1165039	hsa-miR-4427	CLIP-seq
MIRT2454581	hsa-miR-4438	CLIP-seq
MIRT1165041	hsa-miR-4443	CLIP-seq
MIRT1165048	hsa-miR-4478	CLIP-seq
MIRT2575372	hsa-miR-450b-5p	CLIP-seq
MIRT2047707	hsa-miR-4519	CLIP-seq
MIRT1165054	hsa-miR-451b	CLIP-seq
MIRT2575373	hsa-miR-4540	CLIP-seq
MIRT2575374	hsa-miR-4638-3p	CLIP-seq
MIRT1165057	hsa-miR-4643	CLIP-seq
MIRT1165066	hsa-miR-466	CLIP-seq
MIRT2575375	hsa-miR-4671-5p	CLIP-seq
MIRT2575376	hsa-miR-4672	CLIP-seq
MIRT2047712	hsa-miR-4684-5p	CLIP-seq
MIRT2047713	hsa-miR-4691-5p	CLIP-seq
MIRT2047714	hsa-miR-4696	CLIP-seq
MIRT2575377	hsa-miR-4701-5p	CLIP-seq
MIRT1165073	hsa-miR-4714-5p	CLIP-seq
MIRT1165079	hsa-miR-4728-5p	CLIP-seq
MIRT2047717	hsa-miR-4733-3p	CLIP-seq
MIRT2047718	hsa-miR-4772-3p	CLIP-seq
MIRT2047719	hsa-miR-4775	CLIP-seq
MIRT2575379	hsa-miR-4776-3p	CLIP-seq
MIRT1165089	hsa-miR-4789-3p	CLIP-seq
MIRT1165091	hsa-miR-485-5p	CLIP-seq
MIRT1165096	hsa-miR-501-3p	CLIP-seq
MIRT1165097	hsa-miR-502-3p	CLIP-seq
MIRT2575381	hsa-miR-505	CLIP-seq
MIRT2575382	hsa-miR-507	CLIP-seq
MIRT2047723	hsa-miR-508-5p	CLIP-seq
MIRT2454582	hsa-miR-5095	CLIP-seq
MIRT1165104	hsa-miR-516b	CLIP-seq
MIRT2575384	hsa-miR-518a-5p	CLIP-seq
MIRT2575385	hsa-miR-527	CLIP-seq
MIRT1165107	hsa-miR-532-3p	CLIP-seq
MIRT2047726	hsa-miR-532-5p	CLIP-seq
MIRT1165108	hsa-miR-541	CLIP-seq
MIRT2047728	hsa-miR-544	CLIP-seq
MIRT1165109	hsa-miR-548a-3p	CLIP-seq
MIRT2575388	hsa-miR-548ad	CLIP-seq
MIRT1165114	hsa-miR-548e	CLIP-seq
MIRT1165115	hsa-miR-548f	CLIP-seq
MIRT2047730	hsa-miR-552	CLIP-seq
MIRT2575398	hsa-miR-557	CLIP-seq
MIRT2575400	hsa-miR-571	CLIP-seq
MIRT2575401	hsa-miR-588	CLIP-seq
MIRT2276532	hsa-miR-589	CLIP-seq
MIRT2047731	hsa-miR-590-3p	CLIP-seq
MIRT2276533	hsa-miR-593	CLIP-seq
MIRT2454583	hsa-miR-629	CLIP-seq
MIRT1165125	hsa-miR-650	CLIP-seq
MIRT1165127	hsa-miR-654-5p	CLIP-seq
MIRT2575402	hsa-miR-671-5p	CLIP-seq
MIRT1165132	hsa-miR-767-3p	CLIP-seq
MIRT2047738	hsa-miR-767-5p	CLIP-seq
MIRT2575403	hsa-miR-938	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000096	Process	Sulfur amino acid metabolic process	TAS
GO:0005515	Function	Protein binding	IPI	17288554, 23825108, 27771510
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	TAS
GO:0007399	Process	Nervous system development	TAS	8968737
GO:0008168	Function	Methyltransferase activity	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0008652	Process	Amino acid biosynthetic process	IEA
GO:0008705	Function	Methionine synthase activity	IBA
GO:0008705	Function	Methionine synthase activity	IDA	16769880
GO:0008705	Function	Methionine synthase activity	IEA
GO:0008705	Function	Methionine synthase activity	IMP	23825108
GO:0009086	Process	Methionine biosynthetic process	IBA
GO:0009086	Process	Methionine biosynthetic process	IEA
GO:0009086	Process	Methionine biosynthetic process	IMP	23825108
GO:0009235	Process	Cobalamin metabolic process	IEA
GO:0009235	Process	Cobalamin metabolic process	IMP	23825108
GO:0009235	Process	Cobalamin metabolic process	TAS
GO:0016740	Function	Transferase activity	IEA
GO:0031103	Process	Axon regeneration	IEA
GO:0031103	Process	Axon regeneration	ISS
GO:0031419	Function	Cobalamin binding	IEA
GO:0032259	Process	Methylation	IEA
GO:0032259	Process	Methylation	TAS
GO:0042558	Process	Pteridine-containing compound metabolic process	IEA
GO:0046653	Process	Tetrahydrofolate metabolic process	IBA
GO:0046872	Function	Metal ion binding	IEA
GO:0048678	Process	Response to axon injury	IEA
GO:0048678	Process	Response to axon injury	ISS
GO:0050667	Process	Homocysteine metabolic process	IBA
GO:0071267	Process	L-methionine salvage	IEA
GO:0071732	Process	Cellular response to nitric oxide	IEA
GO:0071732	Process	Cellular response to nitric oxide	ISS

Other IDs

• MIM: 156570
• HGNC: 7468
• e!Ensembl: ENSG00000116984

Protein

• UniProt ID: Q99707
• Protein name: Methionine synthase (MS) (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Cobalamin-dependent methionine synthase) (Vitamin-B12 dependent methionine synthase)
• Protein function: Catalyzes the transfer of a methyl group from methylcob(III)alamin (MeCbl) to homocysteine, yielding enzyme-bound cob(I)alamin and methionine in the cytosol (PubMed:16769880, PubMed:17288554, PubMed:27771510). MeCbl is an active form of cobalami
• PDB: 2O2K, 4CCZ
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02574	S-methyl_trans	31 → 338	Homocysteine S-methyltransferase	Family
  PF00809	Pterin_bind	375 → 613	Pterin binding enzyme	Domain
  PF02607	B12-binding_2	671 → 748	B12 binding domain	Domain
  PF02310	B12-binding	773 → 874	B12 binding domain	Domain
  PF02965	Met_synt_B12	965 → 1246	Vitamin B12 dependent methionine synthase, activation domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed. Expressed at the highest levels in pancreas, heart, brain, skeletal muscle and placenta (PubMed:8968735, PubMed:8968737). Expressed at lower levels in lung, liver and kidney (PubMed:8968735, PubMed:8968737). {ECO:0000
• Sequence:

  MSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHA
  RPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNMC
  SAGVARKAAEEVTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQA
  KGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQT
  GEGFVISVSHGEPLCIGLNCALGAAEMRPFIEIIGKCTTAYVLCYPNAGLPNTFGDYDET
  PSMMAKHLKDFAMDGLVNIVGGCCGSTPDHIREIAEAVKNCKPRVPPATAFEGHMLLSGL
  EPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDDG
  MLDGPSAMTRFCNLIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDD
  FLEKARKIKKYGAAMVVMAFDEEGQATETDTKIRVCTRAYHLLVKKLGFNPNDIIFDPNI
  LTIGTGMEEHNLYAINFIHATKVIKETLPGARISGGLSNLSFSFRGMEAIREAMHGVFLY
  HAIKSGMDMGIVNAGNLPVYDDIHKELLQLCEDLIWNKDPEATEKLLRYAQTQGTGGKKV
  IQTDEWRNGPVEERLEYALVKGIEKHIIEDTEEARLNQKKYPRPLNIIEGPLMNGMKIVG
  DLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREETRVLNGTVEEEDPYQGTIVLATV
  KGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILKAALDHKADIIGLSGLITPSLDEM
  IFVAKEMERLAIRIPLLIGGATTSKTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDEN
  LKDEYFEEIMEEYEDIRQDHYESLKERRYLPLSQARKSGFQMDWLSEPHPVKPTFIGTQV
  FEDYDLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKTVGGEARKVYDDAHNMLNTL
  ISQKKLRARGVVGFWPAQSIQDDIHLYAEAAVPQAAEPIATFYGLRQQAEKDSASTEPYY
  CLSDFIAPLHSGIRDYLGLFAVACFGVEELSKAYEDDGDDYSSIMVKALGDRLAEAFAEE
  LHERVRRELWAYCGSEQLDVADLRRLRYKGIRPAPGYPSQPDHTEKLTMWRLADIEQSTG
  IRLTESLAMAPASAVSGLYFSNLKSKYFAVGKISKDQVEDYALRKNISVAEVEKWLGPIL
  GYDTD

• Sequence length: 1265

Pathways

KEGG:

Cysteine and methionine metabolism
Selenocompound metabolism
One carbon pool by folate
Metabolic pathways
Biosynthesis of amino acids
Cobalamin transport and metabolism
Folate transport and metabolism

Reactome:

Methylation
Sulfur amino acid metabolism
Cobalamin (Cbl, vitamin B12) transport and metabolism
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Decreased methionine synthase activity	Pathogenic; Likely pathogenic	rs121913578, rs1190777785	RCV001003947 RCV001003946	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Disorders of Intracellular Cobalamin Metabolism	Pathogenic	rs121913578	RCV000778974	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Epilepsy	Pathogenic	rs121913578	RCV000162189	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Homocystinuria	Pathogenic; Likely pathogenic	rs121913578, rs1190777785	RCV001003947 RCV001003946	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Intellectual disability	Likely pathogenic; Pathogenic	rs1324468065	RCV005626831	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Melanoma	Likely pathogenic	rs1664661222	RCV005913543	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Methylcobalamin deficiency type cblG	Pathogenic; Likely pathogenic	rs752526782, rs1666006480, rs1400658126, rs1558334603, rs138695265, rs778242201, rs2103130072, rs774231870, rs2147922731, rs762727293, rs1664521219, rs794727395, rs1343645070, rs2528337010, rs2528074679, rs772951826, rs776216297, rs2527985401, rs1176062955, rs2528537380, rs2527909396, rs2527833447, rs2528160239, rs1666192928, rs2528435985, rs2528436693, rs2527985163, rs2527854627, rs1324468065, rs1664661129, rs2528240978, rs1663042244, rs2528522105, rs781320871, rs2527974254, rs778563154, rs121913578, rs121913579, rs1661117141, rs797044444, rs797044445, rs121913580, rs121913581, rs752220849, rs192346180, rs765288116, rs2528250134, rs763288919, rs764980259, rs2528240695, rs1572218599, rs2528537363, rs2528177941, rs915986128, rs1269957639, rs2528436006, rs768968736, rs776165231, rs2527889197, rs1666295144, rs767201867, rs2528336317, rs2528241635, rs1180704409, rs1665948819, rs2528336328, rs1346847201, rs536238004, rs145939391, rs1572278166, rs1572309822, rs201718371, rs1662641467, rs1664661222, rs1661544157, rs757963570, rs1224783275, rs1664669480, rs1665277406	RCV001353054 RCV001353055 RCV001782469 RCV003514527 RCV001823618 RCV001837425 RCV001993759 RCV001900088 RCV002033483 RCV001996785 RCV002250130 RCV003514322 RCV002580621 RCV002880567 RCV002996912 RCV005019557 RCV005102850 RCV003629269 RCV003514640 RCV003514684 RCV003514711 RCV003514762 RCV003515287 RCV003515355 RCV003515608 RCV003515610 RCV003513807 RCV003516287 RCV003516288 RCV003516289 RCV003515047 RCV003515794 RCV003514844 RCV003515901 RCV003516102 RCV003515865 RCV000015348 RCV000015350 RCV000015351 RCV000015352 RCV000015354 RCV000015356 RCV000015357 RCV003516004 RCV003629302 RCV003629528 RCV003629572 RCV003630480 RCV003630449 RCV003630644 RCV003630657 RCV003630872 RCV003631009 RCV003631046 RCV003631073 RCV003628747 RCV003629656 RCV003629687 RCV003830230 RCV003835380 RCV003845356 RCV003840798 RCV003865344 RCV003875962 RCV003869900 RCV003990400 RCV003768229 RCV003514413 RCV003514412 RCV000803188 RCV000805410 RCV000805089 RCV000795006 RCV001071198 RCV001059608 RCV001198173 RCV001195906 RCV001244091 RCV001250117 RCV001250118	★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
MTR-related disorder	Likely pathogenic; Pathogenic	rs1359827243, rs1176062955, rs2528524023, rs121913578	RCV003393052 RCV003421021 RCV003408410 RCV005229796	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Neural tube defects, folate-sensitive	Likely pathogenic; Pathogenic	rs1400658126, rs138695265, rs772951826, rs121913580	RCV005006049 RCV005006080 RCV005019557 RCV005016268	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Profound intellectual disability	Pathogenic	rs121913578	RCV000162189	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Thymoma	Likely pathogenic	rs1666295144	RCV005935002	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Acute myeloid leukemia	Benign; Uncertain significance; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDER	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDERS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISTIC DISORDER	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BIPOLAR DISORDER	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST NEOPLASMS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CEREBRAL INFARCTION	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cholangiocarcinoma	Benign; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Chronic lymphocytic leukemia/small lymphocytic lymphoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colorectal cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEPRESSIVE DISORDER	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DIGESTIVE SYSTEM DISORDERS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Benign; Likely benign; Uncertain significance; Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial pancreatic carcinoma	Likely benign; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Benign; Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GASTROINTESTINAL DISEASES	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastrointestinal stromal tumor	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEART DISEASES	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEMATOLOGIC DISEASES	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEMATOLOGICAL DISEASE	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Benign; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HOMOCYSTINURIA-MEGALOBLASTIC ANEMIA, CBLG TYPE	—	HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERHOMOCYSTEINEMIA	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSIVE DISEASE	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
IGA GLOMERULONEPHRITIS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INFERTILITY, MALE	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Benign; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LYMPHOMA	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LYMPHOMA, FOLLICULAR	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MALE INFERTILITY	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Benign; Likely benign; Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MALNUTRITION	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MENTAL DEPRESSION	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEURAL TUBE DEFECT, FOLATE-SENSITIVE	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Neural tube defects, folate-sensitive, susceptibility to	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nonpapillary renal cell carcinoma	Likely benign; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian cancer	Likely benign; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Benign; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SEVERE DEPRESSION	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine carcinosarcoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uveal melanoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Adenocarcinoma	Associate	32894539	★☆☆☆☆ Found in Text Mining only
Adenoma	Associate	31740010	★☆☆☆☆ Found in Text Mining only
Age Related Hearing Impairment 1	Associate	21385350	★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Associate	15201366	★☆☆☆☆ Found in Text Mining only
Anemia Macrocytic	Associate	25526710	★☆☆☆☆ Found in Text Mining only
Anemia Megaloblastic	Associate	9501215	★☆☆☆☆ Found in Text Mining only
Anemia Neonatal	Associate	3828532	★☆☆☆☆ Found in Text Mining only
Aortic Aneurysm Abdominal	Associate	20871623	★☆☆☆☆ Found in Text Mining only
Aortic Dissection	Associate	20871623	★☆☆☆☆ Found in Text Mining only
Attention Deficit Disorder with Hyperactivity	Associate	23650422	★☆☆☆☆ Found in Text Mining only
Autistic Disorder	Inhibit	23437274	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Autistic Disorder	Associate	28094822	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Birth Weight	Associate	35631247	★☆☆☆☆ Found in Text Mining only
Brachydactyly Type E	Inhibit	31951343	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Associate	17595805, 19240236, 19389261, 19706843, 25217320, 27347936, 27404801	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Carcinoma Hepatocellular	Associate	25337902	★☆☆☆☆ Found in Text Mining only
Carcinoma Non Small Cell Lung	Inhibit	15735045	★☆☆☆☆ Found in Text Mining only
Carcinoma Non Small Cell Lung	Associate	20737570	★☆☆☆☆ Found in Text Mining only
Cardiomyopathies	Associate	38168585	★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Associate	27316508, 32068834	★☆☆☆☆ Found in Text Mining only
Celiac Disease	Associate	21688148	★☆☆☆☆ Found in Text Mining only
Cerebral Infarction	Associate	17461517	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Choline Deficiency	Associate	27342765	★☆☆☆☆ Found in Text Mining only
Cleft Palate	Associate	25716564, 27167580	★☆☆☆☆ Found in Text Mining only
Cognition Disorders	Associate	25526710, 25625218	★☆☆☆☆ Found in Text Mining only
Cognitive Dysfunction	Associate	25625218	★☆☆☆☆ Found in Text Mining only
Colitis Ulcerative	Associate	18700049	★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Associate	21603981	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Associate	19776626, 20615890, 21603981, 22719222, 29925788, 31740010, 38514198	★☆☆☆☆ Found in Text Mining only
Communication Disorders	Associate	25526710	★☆☆☆☆ Found in Text Mining only
Congenital contractural arachnodactyly	Associate	27822905	★☆☆☆☆ Found in Text Mining only
Conotruncal cardiac defects	Associate	30165839	★☆☆☆☆ Found in Text Mining only
Convulsions benign familial neonatal dominant form	Associate	9683607	★☆☆☆☆ Found in Text Mining only
Death	Associate	25840420	★☆☆☆☆ Found in Text Mining only
Dementia	Associate	15201366	★☆☆☆☆ Found in Text Mining only
Dental Caries	Associate	37531512	★☆☆☆☆ Found in Text Mining only
Depressive Disorder	Associate	37628752	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Developmental Disabilities	Associate	9501215, 9683607	★☆☆☆☆ Found in Text Mining only
Diabetes Gestational	Associate	35631247, 36313769	★☆☆☆☆ Found in Text Mining only
Dissection Thoracic Aorta	Associate	20871623	★☆☆☆☆ Found in Text Mining only
Down Syndrome	Associate	15585767, 18060320	★☆☆☆☆ Found in Text Mining only
Down Syndrome	Inhibit	31951343	★☆☆☆☆ Found in Text Mining only
Drug Related Side Effects and Adverse Reactions	Associate	17009228, 31181069	★☆☆☆☆ Found in Text Mining only
Esophageal Squamous Cell Carcinoma	Associate	16333305	★☆☆☆☆ Found in Text Mining only
Failure to Thrive	Associate	25526710	★☆☆☆☆ Found in Text Mining only
Folate Malabsorption Hereditary	Associate	15585767, 26266420, 35631247, 9501215	★☆☆☆☆ Found in Text Mining only
Gastrointestinal Neoplasms	Associate	17726616	★☆☆☆☆ Found in Text Mining only
Head and Neck Neoplasms	Associate	20490431	★☆☆☆☆ Found in Text Mining only
Hearing Loss	Associate	21385350	★☆☆☆☆ Found in Text Mining only
Heart Defects Congenital	Associate	26035828, 30911047, 37296303	★☆☆☆☆ Found in Text Mining only
Heart Septal Defects Ventricular	Associate	29293099	★☆☆☆☆ Found in Text Mining only
Hereditary Breast and Ovarian Cancer Syndrome	Associate	17595805	★☆☆☆☆ Found in Text Mining only
Homocystinuria	Associate	3828532	★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Homocystinuria Megaloblastic Anemia due to Defect in Cobalamin Metabolism CblE Complementation Type	Associate	3384945	★☆☆☆☆ Found in Text Mining only
Hyperhomocysteinemia	Associate	12068375, 9501215	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hypertension Pulmonary	Associate	38168585	★☆☆☆☆ Found in Text Mining only
Leukemia	Associate	20101025	★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid Acute	Associate	20101025	★☆☆☆☆ Found in Text Mining only
Leukoencephalopathies	Associate	25526710	★☆☆☆☆ Found in Text Mining only
Lymphoma	Associate	11342450, 15138479, 15551285	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lymphoma Follicular	Associate	15198953	★☆☆☆☆ Found in Text Mining only
Lymphoma Large B Cell Diffuse	Associate	15198953	★☆☆☆☆ Found in Text Mining only
Lymphoma Non Hodgkin	Associate	12648076, 15198953	★☆☆☆☆ Found in Text Mining only
Malaria	Associate	27198213	★☆☆☆☆ Found in Text Mining only
Methylcobalamin Deficiency CblG Type	Associate	12068375, 25526710, 31951343, 38168585, 9683607	★☆☆☆☆ Found in Text Mining only
Methylmalonic Aciduria and Homocystinuria CblF Type	Associate	32068834	★☆☆☆☆ Found in Text Mining only
Microphthalmia Syndromic 10	Associate	25526710	★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Inhibit	17546637	★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Associate	17546637	★☆☆☆☆ Found in Text Mining only
Multiple Sclerosis	Associate	25625218	★☆☆☆☆ Found in Text Mining only
Muscle Hypotonia	Associate	25526710	★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	15735045, 16333305, 21603981, 25531253, 30587867, 34799699, 34799701	★☆☆☆☆ Found in Text Mining only
Neural Tube Defects	Associate	25293959, 26334892, 30848279	★☆☆☆☆ Found in Text Mining only
Neurocognitive Disorders	Associate	21618410, 25526710	★☆☆☆☆ Found in Text Mining only
Neurologic Manifestations	Associate	23437274, 32068834	★☆☆☆☆ Found in Text Mining only
Open Bite	Associate	35830630	★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Associate	29474406	★☆☆☆☆ Found in Text Mining only
Persistent Infection	Associate	31181069	★☆☆☆☆ Found in Text Mining only
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	19020309, 28582843	★☆☆☆☆ Found in Text Mining only
Premature Birth	Associate	35631247	★☆☆☆☆ Found in Text Mining only
Proctitis	Associate	18700049	★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Associate	27808252, 28724269, 32770085	★☆☆☆☆ Found in Text Mining only
Severe Acute Respiratory Syndrome	Associate	25526710	★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Associate	17596206, 20490431	★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Associate	25840420	★☆☆☆☆ Found in Text Mining only
Taste Disorders	Associate	26989453	★☆☆☆☆ Found in Text Mining only
Uterine Cervical Dysplasia	Associate	24089416	★☆☆☆☆ Found in Text Mining only
Uterine Cervicitis	Associate	32295543	★☆☆☆☆ Found in Text Mining only
Vascular Diseases	Associate	21688148, 9501215	★☆☆☆☆ Found in Text Mining only
Xanthomatosis Cerebrotendinous	Associate	15612980	★☆☆☆☆ Found in Text Mining only