Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
4542
Gene name Gene Name - the full gene name approved by the HGNC.
Myosin IF
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MYO1F
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
19p13.2
Summary Summary of gene provided in NCBI Entrez Gene.
Myosins are molecular motors that use the energy from ATP hydrolysis to generate force on actin filaments. The protein encoded by this gene is an unconventional myosin that may be involved in the intracellular movement of membrane-enclosed compartments. T
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT611103 hsa-miR-7110-3p HITS-CLIP 19536157
MIRT611102 hsa-miR-6817-3p HITS-CLIP 19536157
MIRT611101 hsa-miR-626 HITS-CLIP 19536157
MIRT611100 hsa-miR-6876-3p HITS-CLIP 19536157
MIRT611099 hsa-miR-6895-3p HITS-CLIP 19536157
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000146 Function Microfilament motor activity IBA 21873635
GO:0003779 Function Actin binding NAS 9119401
GO:0005515 Function Protein binding IPI 32296183
GO:0005516 Function Calmodulin binding IEA
GO:0005524 Function ATP binding NAS 9119401
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
601480 7600 ENSG00000142347
Protein
UniProt ID O00160
Protein name Unconventional myosin-If (Myosin-Ie)
Protein function Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00063 Myosin_head 19 677 Myosin head (motor domain) Domain
PF06017 Myosin_TH1 717 915 Unconventional myosin tail, actin- and lipid-binding Domain
PF00018 SH3_1 1047 1092 SH3 domain Domain
Sequence
MGSKERFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPF
KQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAA
KYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGG
EPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSD
TYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVESV
DLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYAR
LFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK
AEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLL
QKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFL
RMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENR
VKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLRAV
NMEPDQYQMGSTKVFVK
NPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREEA
SNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKRERVDFADSVTKYDRRFKPIKR
DLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFFILQEDAAD
SFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEGWGGGGTRSVTFSRGFGD
LAVLKVGGRTLTVSV
GDGLPKSSKPTRKGMAKGKPRRSSQAPTRAAPAPPRGMDRNGVPP
SARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARPPSEHNTEFLNVPDQGMAGMQR
KRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWWK
GRLHGQEGLFPG
NYVEKI
Sequence length 1098
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  Motor proteins
Pathogenic Escherichia coli infection
 
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Nonsyndromic deafness Nonsyndromic Deafness rs606231410, rs794729665, rs730880338, rs1566538321 22938506, 19027848, 12486594
Unknown
Disease term Disease name Evidence References Source
Metabolic Syndrome Metabolic Syndrome GWAS
Associations from Text Mining
Disease Name Relationship Type References
Arthritis Rheumatoid Associate 40595039
Coronary Artery Disease Associate 31245869
Floating harbor syndrome Associate 27934915
Hearing Loss Associate 19027848, 22938506
Hyperlipidemias Associate 31245869
Kabuki syndrome Associate 28933623
Lupus Erythematosus Systemic Associate 39290707
Lymphoma T Cell Peripheral Associate 34147695
MINOCA Associate 31245869
Moyamoya Disease Associate 39290707