MICOS10 (mitochondrial contact site and cristae organizing system subunit 10)

Gene
Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
440574
Gene name Gene Name - the full gene name approved by the HGNC.
Mitochondrial contact site and cristae organizing system subunit 10
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MICOS10
Synonyms (NCBI Gene) Gene synonyms aliases
C1orf151, MINOS1, MIO10, Mic10
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1p36.13
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide all(18)
GO ID Ontology Definition Evidence Reference
GO:0001401 Component SAM complex HDA 26477565
GO:0005515 Function Protein binding IPI 25764979, 31644573, 32296183
GO:0005739 Component Mitochondrion HDA 20833797
GO:0005739 Component Mitochondrion HTP 34800366
GO:0005739 Component Mitochondrion IBA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
616574 32068 ENSG00000173436
Protein
Gene Gene ontology Other IDs Protein Associated diseases
UniProt ID Q5TGZ0
Protein name MICOS complex subunit MIC10 (Mitochondrial inner membrane organizing system protein 1)
Protein function Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. {ECO:
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04418 DUF543 1 → 63 Domain of unknown function (DUF543) Domain
Sequence
Sequence length 78
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (2)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Hyperthyroidism Hyperthyroidism N/A N/A GWAS
Hypothyroidism Hypothyroidism N/A N/A GWAS