Gene Gene information from NCBI Gene database.
Entrez ID 440515
Gene name Zinc finger protein 506
Gene symbol ZNF506
Synonyms (NCBI Gene)
-
Chromosome 19
Chromosome location 19p13.11
miRNA miRNA information provided by mirtarbase database.
490
miRTarBase ID miRNA Experiments Reference
MIRT050100 hsa-miR-26a-5p CLASH 23622248
MIRT047899 hsa-miR-30c-5p CLASH 23622248
MIRT1527184 hsa-miR-103a CLIP-seq
MIRT1527185 hsa-miR-107 CLIP-seq
MIRT1527186 hsa-miR-125a-5p CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
10
GO ID Ontology Definition Evidence Reference
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0003677 Function DNA binding IEA
GO:0005634 Component Nucleus IEA
GO:0005730 Component Nucleolus IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q5JVG8
Protein name Zinc finger protein 506
Protein function May be involved in transcriptional regulation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01352 KRAB 3 44 KRAB box Family
PF00096 zf-C2H2 201 223 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 229 251 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 257 279 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 285 307 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 313 335 Zinc finger, C2H2 type Domain
PF13912 zf-C2H2_6 341 366 Domain
PF00096 zf-C2H2 369 391 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 397 419 Zinc finger, C2H2 type Domain
Sequence
MGPLQFRDVAIEFSLEEWHCLDAAQRNLYRDVMLENYRNLIFLGIVVSKPNLITCLEQGK
KPLTMKRHEMIAKPPVMYSHFAQDLWSEQSIKDSFQKVILRRYEKCRHDNLQLKKGCESV
DECPVHKRGYNGLKQCLATTQRKIFQCDEYVKFLHKFSNSNKHKIRDTGKKSFKCIEYGK
TFNQSSTRTTYKKIDAGEKRYKCEECGKAYKQSSHLTTHKKIHTGEKPYKCEECGKAYKQ
SCNLTTHKIIH
TGEKPYRCRECGKAFNHPATLFSHKKIHTGEKPYKCDKCGKAFISSSTL
TKHEIIH
TGEKPYKCEECGKAFNRSSNLTKHKRIHTGDVPYKCDECGKTFTWYSSLSKHK
RAHTGE
KPYKCEECGKAFTAFSTLTEHKIIHTGEKPYKCEECGKAFNWSSALNKHKKIHI
RQKPCIVKNVENLLNVPQPLISIR
Sequence length 444
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Generic Transcription Pathway
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
3
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
DEMENTIA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
EBV-positive nodal T- and NK-cell lymphoma Likely benign ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Adenocarcinoma of Lung Associate 39267056
★☆☆☆☆
Found in Text Mining only
Hyperglycemic Hyperosmolar Nonketotic Coma Associate 37240180
★☆☆☆☆
Found in Text Mining only
Inflammation Associate 37240180
★☆☆☆☆
Found in Text Mining only
Periodontitis Associate 37240180
★☆☆☆☆
Found in Text Mining only