MLN (motilin)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID 4295
Gene name Motilin
Gene symbol MLN
Synonyms (NCBI Gene)
-
Chromosome 6
Chromosome location 6p21.31
Summary This gene encodes a small peptide hormone that is secreted by cells of the small intestine to regulate gastrointestinal contractions and motility. Proteolytic processing of the secreted protein produces the mature peptide and a byproduct referred to as mo
miRNA miRNA information provided by mirtarbase database.
19
Gene miRNA Gene ontology Other IDs Protein Pathways
Show/Hide all (19)
miRTarBase ID miRNA Experiments Reference
MIRT018464 hsa-miR-335-5p Microarray 18185580
MIRT661928 hsa-miR-4779 HITS-CLIP 23824327
MIRT661927 hsa-miR-4762-5p HITS-CLIP 23824327
MIRT661926 hsa-miR-186-3p HITS-CLIP 23824327
MIRT661925 hsa-miR-150-5p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
7
Gene miRNA Gene ontology Other IDs Protein Pathways
Show/Hide all (7)
GO ID Ontology Definition Evidence Reference
GO:0005179 Function Hormone activity IEA
GO:0005515 Function Protein binding IPI 32296183
GO:0005576 Component Extracellular region IEA
GO:0005576 Component Extracellular region TAS
GO:0007165 Process Signal transduction IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Pathways
MIM HGNC e!Ensembl
158270 7141 ENSG00000096395
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Pathways
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P12872
Protein name Promotilin [Cleaved into: Motilin; Motilin-associated peptide (MAP)]
Protein function Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
PDB 1LBJ , 8IBV
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04644 Motilin_ghrelin 27 → 53 Motilin/ghrelin Family
PF04643 Motilin_assoc 61 → 115 Motilin/ghrelin-associated peptide Family
Sequence
Sequence length 115
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways
  KEGG  Reactome
  Neuroactive ligand-receptor interaction
Hormone signaling 		  Peptide ligand-binding receptors
G alpha (q) signalling events