RAB8A (RAB8A, member RAS oncogene family)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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4218 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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RAB8A, member RAS oncogene family |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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RAB8A |
Synonyms (NCBI Gene)
Gene synonyms aliases
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MEL, RAB8 |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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MEL |
Chromosome
Chromosome number
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19 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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19p13.11 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endo |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | P61006 | ||||||||||
Protein name | Ras-related protein Rab-8A (EC 3.6.5.2) (Oncogene c-mel) | ||||||||||
Protein function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to r | ||||||||||
PDB | 3QBT , 3TNF , 4LHV , 4LHW , 4LHX , 4LHY , 4LHZ , 4LI0 , 5SZI , 6RIR , 6SQ2 , 6STF , 6STG , 6WHE , 6YX5 , 6ZSI , 6ZSJ , 7BWT , 7LWB , 9IKQ | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 207 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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