Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	4200
Gene name Gene Name - the full gene name approved by the HGNC.	Malic enzyme 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ME2
Synonyms (NCBI Gene) Gene synonyms aliases	ODS1
Chromosome Chromosome number	18
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	18q21.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been s

Show/Hide all(313)

miRTarBase ID	miRNA	Experiments	Reference
MIRT049487	hsa-miR-92a-3p	CLASH	23622248
MIRT1139632	hsa-miR-1228	CLIP-seq
MIRT1139633	hsa-miR-124	CLIP-seq
MIRT1139634	hsa-miR-1247	CLIP-seq
MIRT1139635	hsa-miR-1827	CLIP-seq
MIRT1139636	hsa-miR-24	CLIP-seq
MIRT1139637	hsa-miR-2467-3p	CLIP-seq
MIRT1139638	hsa-miR-3074-5p	CLIP-seq
MIRT1139639	hsa-miR-3122	CLIP-seq
MIRT1139640	hsa-miR-3160-3p	CLIP-seq
MIRT1139641	hsa-miR-3192	CLIP-seq
MIRT1139642	hsa-miR-3202	CLIP-seq
MIRT1139643	hsa-miR-338-3p	CLIP-seq
MIRT1139644	hsa-miR-3545-5p	CLIP-seq
MIRT1139645	hsa-miR-3612	CLIP-seq
MIRT1139646	hsa-miR-3619-3p	CLIP-seq
MIRT1139647	hsa-miR-3652	CLIP-seq
MIRT1139648	hsa-miR-3675-3p	CLIP-seq
MIRT1139649	hsa-miR-3689a-3p	CLIP-seq
MIRT1139650	hsa-miR-3689c	CLIP-seq
MIRT1139651	hsa-miR-3714	CLIP-seq
MIRT1139652	hsa-miR-3910	CLIP-seq
MIRT1139653	hsa-miR-3913-5p	CLIP-seq
MIRT1139654	hsa-miR-3926	CLIP-seq
MIRT1139655	hsa-miR-3929	CLIP-seq
MIRT1139656	hsa-miR-3934	CLIP-seq
MIRT1139657	hsa-miR-3975	CLIP-seq
MIRT1139658	hsa-miR-4257	CLIP-seq
MIRT1139659	hsa-miR-4270	CLIP-seq
MIRT1139660	hsa-miR-4284	CLIP-seq
MIRT1139661	hsa-miR-4290	CLIP-seq
MIRT1139662	hsa-miR-4297	CLIP-seq
MIRT1139663	hsa-miR-4419b	CLIP-seq
MIRT1139664	hsa-miR-4430	CLIP-seq
MIRT1139665	hsa-miR-4433	CLIP-seq
MIRT1139666	hsa-miR-4441	CLIP-seq
MIRT1139667	hsa-miR-4455	CLIP-seq
MIRT1139668	hsa-miR-4466	CLIP-seq
MIRT1139669	hsa-miR-4478	CLIP-seq
MIRT1139670	hsa-miR-4487	CLIP-seq
MIRT1139671	hsa-miR-4505	CLIP-seq
MIRT1139672	hsa-miR-4517	CLIP-seq
MIRT1139673	hsa-miR-4530	CLIP-seq
MIRT1139674	hsa-miR-4533	CLIP-seq
MIRT1139675	hsa-miR-4535	CLIP-seq
MIRT1139676	hsa-miR-4645-5p	CLIP-seq
MIRT1139677	hsa-miR-4662a-3p	CLIP-seq
MIRT1139678	hsa-miR-4673	CLIP-seq
MIRT1139679	hsa-miR-4684-5p	CLIP-seq
MIRT1139680	hsa-miR-4704-5p	CLIP-seq
MIRT1139681	hsa-miR-4722-3p	CLIP-seq
MIRT1139682	hsa-miR-4728-5p	CLIP-seq
MIRT1139683	hsa-miR-4743	CLIP-seq
MIRT1139684	hsa-miR-4746-3p	CLIP-seq
MIRT1139685	hsa-miR-4776-5p	CLIP-seq
MIRT1139686	hsa-miR-4796-3p	CLIP-seq
MIRT1139687	hsa-miR-490-3p	CLIP-seq
MIRT1139688	hsa-miR-506	CLIP-seq
MIRT1139689	hsa-miR-520g	CLIP-seq
MIRT1139690	hsa-miR-520h	CLIP-seq
MIRT1139691	hsa-miR-541	CLIP-seq
MIRT1139692	hsa-miR-548c-3p	CLIP-seq
MIRT1139693	hsa-miR-548p	CLIP-seq
MIRT1139694	hsa-miR-548s	CLIP-seq
MIRT1139695	hsa-miR-550a	CLIP-seq
MIRT1139696	hsa-miR-558	CLIP-seq
MIRT1139697	hsa-miR-605	CLIP-seq
MIRT1139698	hsa-miR-609	CLIP-seq
MIRT1139699	hsa-miR-647	CLIP-seq
MIRT1139700	hsa-miR-650	CLIP-seq
MIRT1139701	hsa-miR-654-5p	CLIP-seq
MIRT1139702	hsa-miR-665	CLIP-seq
MIRT1139703	hsa-miR-675	CLIP-seq
MIRT1139704	hsa-miR-766	CLIP-seq
MIRT1139705	hsa-miR-873	CLIP-seq
MIRT1139706	hsa-miR-890	CLIP-seq
MIRT1139635	hsa-miR-1827	CLIP-seq
MIRT1139649	hsa-miR-3689a-3p	CLIP-seq
MIRT1139650	hsa-miR-3689c	CLIP-seq
MIRT1139682	hsa-miR-4728-5p	CLIP-seq
MIRT1139691	hsa-miR-541	CLIP-seq
MIRT1139701	hsa-miR-654-5p	CLIP-seq
MIRT2039505	hsa-miR-1293	CLIP-seq
MIRT1139637	hsa-miR-2467-3p	CLIP-seq
MIRT1139639	hsa-miR-3122	CLIP-seq
MIRT2039506	hsa-miR-3165	CLIP-seq
MIRT1139649	hsa-miR-3689a-3p	CLIP-seq
MIRT1139650	hsa-miR-3689c	CLIP-seq
MIRT1139653	hsa-miR-3913-5p	CLIP-seq
MIRT1139654	hsa-miR-3926	CLIP-seq
MIRT1139655	hsa-miR-3929	CLIP-seq
MIRT1139663	hsa-miR-4419b	CLIP-seq
MIRT1139669	hsa-miR-4478	CLIP-seq
MIRT2039507	hsa-miR-4483	CLIP-seq
MIRT1139682	hsa-miR-4728-5p	CLIP-seq
MIRT1139686	hsa-miR-4796-3p	CLIP-seq
MIRT1139689	hsa-miR-520g	CLIP-seq
MIRT1139690	hsa-miR-520h	CLIP-seq
MIRT1139632	hsa-miR-1228	CLIP-seq
MIRT2269467	hsa-miR-1273e	CLIP-seq
MIRT2039505	hsa-miR-1293	CLIP-seq
MIRT2269468	hsa-miR-138	CLIP-seq
MIRT2269469	hsa-miR-146a	CLIP-seq
MIRT2269470	hsa-miR-146b-5p	CLIP-seq
MIRT1139635	hsa-miR-1827	CLIP-seq
MIRT2269471	hsa-miR-194	CLIP-seq
MIRT2269472	hsa-miR-2114	CLIP-seq
MIRT2269473	hsa-miR-224	CLIP-seq
MIRT1139636	hsa-miR-24	CLIP-seq
MIRT1139637	hsa-miR-2467-3p	CLIP-seq
MIRT1139639	hsa-miR-3122	CLIP-seq
MIRT1139640	hsa-miR-3160-3p	CLIP-seq
MIRT2039506	hsa-miR-3165	CLIP-seq
MIRT1139641	hsa-miR-3192	CLIP-seq
MIRT1139642	hsa-miR-3202	CLIP-seq
MIRT1139645	hsa-miR-3612	CLIP-seq
MIRT2269474	hsa-miR-3617	CLIP-seq
MIRT1139649	hsa-miR-3689a-3p	CLIP-seq
MIRT1139650	hsa-miR-3689c	CLIP-seq
MIRT1139653	hsa-miR-3913-5p	CLIP-seq
MIRT1139654	hsa-miR-3926	CLIP-seq
MIRT1139655	hsa-miR-3929	CLIP-seq
MIRT1139658	hsa-miR-4257	CLIP-seq
MIRT1139660	hsa-miR-4284	CLIP-seq
MIRT1139663	hsa-miR-4419b	CLIP-seq
MIRT2269475	hsa-miR-4456	CLIP-seq
MIRT1139669	hsa-miR-4478	CLIP-seq
MIRT2039507	hsa-miR-4483	CLIP-seq
MIRT1139670	hsa-miR-4487	CLIP-seq
MIRT1139674	hsa-miR-4533	CLIP-seq
MIRT2269476	hsa-miR-4649-3p	CLIP-seq
MIRT2269477	hsa-miR-4705	CLIP-seq
MIRT2269478	hsa-miR-4722-5p	CLIP-seq
MIRT1139682	hsa-miR-4728-5p	CLIP-seq
MIRT2269479	hsa-miR-4768-3p	CLIP-seq
MIRT1139686	hsa-miR-4796-3p	CLIP-seq
MIRT2269480	hsa-miR-485-5p	CLIP-seq
MIRT1139687	hsa-miR-490-3p	CLIP-seq
MIRT1139689	hsa-miR-520g	CLIP-seq
MIRT1139690	hsa-miR-520h	CLIP-seq
MIRT1139691	hsa-miR-541	CLIP-seq
MIRT1139696	hsa-miR-558	CLIP-seq
MIRT2269481	hsa-miR-641	CLIP-seq
MIRT1139700	hsa-miR-650	CLIP-seq
MIRT1139701	hsa-miR-654-5p	CLIP-seq
MIRT1139704	hsa-miR-766	CLIP-seq
MIRT1139706	hsa-miR-890	CLIP-seq
MIRT2269482	hsa-miR-940	CLIP-seq
MIRT2269467	hsa-miR-1273e	CLIP-seq
MIRT2269469	hsa-miR-146a	CLIP-seq
MIRT2269470	hsa-miR-146b-5p	CLIP-seq
MIRT1139635	hsa-miR-1827	CLIP-seq
MIRT1139637	hsa-miR-2467-3p	CLIP-seq
MIRT1139640	hsa-miR-3160-3p	CLIP-seq
MIRT1139641	hsa-miR-3192	CLIP-seq
MIRT1139642	hsa-miR-3202	CLIP-seq
MIRT1139645	hsa-miR-3612	CLIP-seq
MIRT1139649	hsa-miR-3689a-3p	CLIP-seq
MIRT1139650	hsa-miR-3689c	CLIP-seq
MIRT1139655	hsa-miR-3929	CLIP-seq
MIRT1139658	hsa-miR-4257	CLIP-seq
MIRT1139663	hsa-miR-4419b	CLIP-seq
MIRT1139669	hsa-miR-4478	CLIP-seq
MIRT1139670	hsa-miR-4487	CLIP-seq
MIRT1139674	hsa-miR-4533	CLIP-seq
MIRT1139682	hsa-miR-4728-5p	CLIP-seq
MIRT2269479	hsa-miR-4768-3p	CLIP-seq
MIRT1139687	hsa-miR-490-3p	CLIP-seq
MIRT1139691	hsa-miR-541	CLIP-seq
MIRT1139696	hsa-miR-558	CLIP-seq
MIRT1139700	hsa-miR-650	CLIP-seq
MIRT1139701	hsa-miR-654-5p	CLIP-seq
MIRT1139704	hsa-miR-766	CLIP-seq
MIRT1139634	hsa-miR-1247	CLIP-seq
MIRT2453875	hsa-miR-1268	CLIP-seq
MIRT2453876	hsa-miR-1268b	CLIP-seq
MIRT2453877	hsa-miR-1279	CLIP-seq
MIRT2453878	hsa-miR-200b	CLIP-seq
MIRT2453879	hsa-miR-200c	CLIP-seq
MIRT1139642	hsa-miR-3202	CLIP-seq
MIRT2453880	hsa-miR-3613-3p	CLIP-seq
MIRT2453881	hsa-miR-3671	CLIP-seq
MIRT1139648	hsa-miR-3675-3p	CLIP-seq
MIRT2453882	hsa-miR-371b-5p	CLIP-seq
MIRT1139655	hsa-miR-3929	CLIP-seq
MIRT2453883	hsa-miR-429	CLIP-seq
MIRT2453884	hsa-miR-4318	CLIP-seq
MIRT1139663	hsa-miR-4419b	CLIP-seq
MIRT1139667	hsa-miR-4455	CLIP-seq
MIRT1139669	hsa-miR-4478	CLIP-seq
MIRT2453885	hsa-miR-4486	CLIP-seq
MIRT1139674	hsa-miR-4533	CLIP-seq
MIRT1139679	hsa-miR-4684-5p	CLIP-seq
MIRT2453886	hsa-miR-4693-5p	CLIP-seq
MIRT1139683	hsa-miR-4743	CLIP-seq
MIRT1139692	hsa-miR-548c-3p	CLIP-seq
MIRT2453887	hsa-miR-585	CLIP-seq
MIRT1139697	hsa-miR-605	CLIP-seq
MIRT1139698	hsa-miR-609	CLIP-seq
MIRT2453888	hsa-miR-892a	CLIP-seq
MIRT1139634	hsa-miR-1247	CLIP-seq
MIRT2453875	hsa-miR-1268	CLIP-seq
MIRT2453876	hsa-miR-1268b	CLIP-seq
MIRT1139648	hsa-miR-3675-3p	CLIP-seq
MIRT1139667	hsa-miR-4455	CLIP-seq
MIRT2453885	hsa-miR-4486	CLIP-seq
MIRT1139679	hsa-miR-4684-5p	CLIP-seq
MIRT1139683	hsa-miR-4743	CLIP-seq
MIRT1139692	hsa-miR-548c-3p	CLIP-seq
MIRT2453887	hsa-miR-585	CLIP-seq
MIRT1139697	hsa-miR-605	CLIP-seq
MIRT1139698	hsa-miR-609	CLIP-seq
MIRT1139634	hsa-miR-1247	CLIP-seq
MIRT2453875	hsa-miR-1268	CLIP-seq
MIRT2453876	hsa-miR-1268b	CLIP-seq
MIRT2269467	hsa-miR-1273e	CLIP-seq
MIRT2039505	hsa-miR-1293	CLIP-seq
MIRT2269469	hsa-miR-146a	CLIP-seq
MIRT2269470	hsa-miR-146b-5p	CLIP-seq
MIRT1139635	hsa-miR-1827	CLIP-seq
MIRT2269471	hsa-miR-194	CLIP-seq
MIRT2269472	hsa-miR-2114	CLIP-seq
MIRT1139637	hsa-miR-2467-3p	CLIP-seq
MIRT1139639	hsa-miR-3122	CLIP-seq
MIRT2039506	hsa-miR-3165	CLIP-seq
MIRT1139641	hsa-miR-3192	CLIP-seq
MIRT1139642	hsa-miR-3202	CLIP-seq
MIRT1139645	hsa-miR-3612	CLIP-seq
MIRT1139648	hsa-miR-3675-3p	CLIP-seq
MIRT1139649	hsa-miR-3689a-3p	CLIP-seq
MIRT1139650	hsa-miR-3689c	CLIP-seq
MIRT1139653	hsa-miR-3913-5p	CLIP-seq
MIRT1139654	hsa-miR-3926	CLIP-seq
MIRT1139655	hsa-miR-3929	CLIP-seq
MIRT1139658	hsa-miR-4257	CLIP-seq
MIRT1139663	hsa-miR-4419b	CLIP-seq
MIRT1139667	hsa-miR-4455	CLIP-seq
MIRT1139669	hsa-miR-4478	CLIP-seq
MIRT2039507	hsa-miR-4483	CLIP-seq
MIRT2453885	hsa-miR-4486	CLIP-seq
MIRT1139674	hsa-miR-4533	CLIP-seq
MIRT2568777	hsa-miR-4667-3p	CLIP-seq
MIRT1139679	hsa-miR-4684-5p	CLIP-seq
MIRT2269478	hsa-miR-4722-5p	CLIP-seq
MIRT1139682	hsa-miR-4728-5p	CLIP-seq
MIRT1139683	hsa-miR-4743	CLIP-seq
MIRT2269479	hsa-miR-4768-3p	CLIP-seq
MIRT1139686	hsa-miR-4796-3p	CLIP-seq
MIRT1139687	hsa-miR-490-3p	CLIP-seq
MIRT1139689	hsa-miR-520g	CLIP-seq
MIRT1139690	hsa-miR-520h	CLIP-seq
MIRT1139691	hsa-miR-541	CLIP-seq
MIRT1139692	hsa-miR-548c-3p	CLIP-seq
MIRT1139694	hsa-miR-548s	CLIP-seq
MIRT2453887	hsa-miR-585	CLIP-seq
MIRT1139697	hsa-miR-605	CLIP-seq
MIRT1139698	hsa-miR-609	CLIP-seq
MIRT1139700	hsa-miR-650	CLIP-seq
MIRT1139701	hsa-miR-654-5p	CLIP-seq
MIRT1139704	hsa-miR-766	CLIP-seq
MIRT1139706	hsa-miR-890	CLIP-seq
MIRT2269482	hsa-miR-940	CLIP-seq
MIRT1139634	hsa-miR-1247	CLIP-seq
MIRT2453875	hsa-miR-1268	CLIP-seq
MIRT2453876	hsa-miR-1268b	CLIP-seq
MIRT2269467	hsa-miR-1273e	CLIP-seq
MIRT2039505	hsa-miR-1293	CLIP-seq
MIRT2269469	hsa-miR-146a	CLIP-seq
MIRT2269470	hsa-miR-146b-5p	CLIP-seq
MIRT1139635	hsa-miR-1827	CLIP-seq
MIRT2269472	hsa-miR-2114	CLIP-seq
MIRT1139637	hsa-miR-2467-3p	CLIP-seq
MIRT1139639	hsa-miR-3122	CLIP-seq
MIRT1139640	hsa-miR-3160-3p	CLIP-seq
MIRT2039506	hsa-miR-3165	CLIP-seq
MIRT1139641	hsa-miR-3192	CLIP-seq
MIRT1139642	hsa-miR-3202	CLIP-seq
MIRT1139645	hsa-miR-3612	CLIP-seq
MIRT2684774	hsa-miR-3622a-3p	CLIP-seq
MIRT2684775	hsa-miR-3622b-3p	CLIP-seq
MIRT1139648	hsa-miR-3675-3p	CLIP-seq
MIRT1139649	hsa-miR-3689a-3p	CLIP-seq
MIRT1139650	hsa-miR-3689c	CLIP-seq
MIRT1139653	hsa-miR-3913-5p	CLIP-seq
MIRT1139654	hsa-miR-3926	CLIP-seq
MIRT1139655	hsa-miR-3929	CLIP-seq
MIRT1139658	hsa-miR-4257	CLIP-seq
MIRT1139663	hsa-miR-4419b	CLIP-seq
MIRT1139667	hsa-miR-4455	CLIP-seq
MIRT1139669	hsa-miR-4478	CLIP-seq
MIRT2039507	hsa-miR-4483	CLIP-seq
MIRT2453885	hsa-miR-4486	CLIP-seq
MIRT1139670	hsa-miR-4487	CLIP-seq
MIRT1139674	hsa-miR-4533	CLIP-seq
MIRT1139679	hsa-miR-4684-5p	CLIP-seq
MIRT2269478	hsa-miR-4722-5p	CLIP-seq
MIRT1139682	hsa-miR-4728-5p	CLIP-seq
MIRT1139683	hsa-miR-4743	CLIP-seq
MIRT2269479	hsa-miR-4768-3p	CLIP-seq
MIRT1139686	hsa-miR-4796-3p	CLIP-seq
MIRT1139687	hsa-miR-490-3p	CLIP-seq
MIRT1139689	hsa-miR-520g	CLIP-seq
MIRT1139690	hsa-miR-520h	CLIP-seq
MIRT1139691	hsa-miR-541	CLIP-seq
MIRT1139692	hsa-miR-548c-3p	CLIP-seq
MIRT1139696	hsa-miR-558	CLIP-seq
MIRT2453887	hsa-miR-585	CLIP-seq
MIRT1139697	hsa-miR-605	CLIP-seq
MIRT1139698	hsa-miR-609	CLIP-seq
MIRT1139700	hsa-miR-650	CLIP-seq
MIRT1139701	hsa-miR-654-5p	CLIP-seq
MIRT1139706	hsa-miR-890	CLIP-seq
MIRT2269482	hsa-miR-940	CLIP-seq

Show/Hide all(17)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004470	Function	Malic enzyme activity	IBA	21873635
GO:0004470	Function	Malic enzyme activity	IMP	23334421
GO:0004471	Function	Malate dehydrogenase (decarboxylating) (NAD+) activity	IEA
GO:0004473	Function	Malate dehydrogenase (decarboxylating) (NADP+) activity	IBA	21873635
GO:0005739	Component	Mitochondrion	IBA	21873635
GO:0005739	Component	Mitochondrion	IDA
GO:0005759	Component	Mitochondrial matrix	TAS
GO:0006090	Process	Pyruvate metabolic process	IBA	21873635
GO:0006099	Process	Tricarboxylic acid cycle	TAS
GO:0006108	Process	Malate metabolic process	IBA	21873635
GO:0008948	Function	Oxaloacetate decarboxylase activity	IEA
GO:0009055	Function	Electron transfer activity	TAS	1993674
GO:0022900	Process	Electron transport chain	IEA
GO:0043231	Component	Intracellular membrane-bounded organelle	IDA
GO:0046872	Function	Metal ion binding	IEA
GO:0051287	Function	NAD binding	IEA
GO:1902031	Process	Regulation of NADP metabolic process	IMP	23334421

MIM	HGNC	e!Ensembl
154270	6984	ENSG00000082212

Protein

UniProt ID

P23368

Protein name

NAD-dependent malic enzyme, mitochondrial (NAD-ME) (EC 1.1.1.38) (Malic enzyme 2)

Protein function

NAD-dependent mitochondrial malic enzyme that catalyzes the oxidative decarboxylation of malate to pyruvate.

PDB

1DO8 , 1EFK , 1EFL , 1GZ3 , 1GZ4 , 1PJ2 , 1PJ3 , 1PJ4 , 1PJL , 1QR6 , 7BSJ , 7BSK , 7BSL , 7XDE , 7XDF , 7XDG , 9AYI

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00390	malic	89 → 270	Malic enzyme, N-terminal domain	Domain
PF03949	Malic_M	280 → 535	Malic enzyme, NAD binding domain	Domain

Sequence

MLSRLRVVSTTCTLACRHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIET
QDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLAC
SQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIP
VGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFYMGLYQKRDRTQQYDDLIDEFMK
AITDRYGRNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVISK
PISEHKILFLGAGEAALGIANLIVMSMVENGLSEQEAQKKIWMFDKYGLLVKGRKAKIDS
YQEPFTHSAPESIPDTFEDAVNILKPSTIIGVAGAGRLFTPDVIRAMASINERPVIFALS
NPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLTDGRVFTPGQGNNVYIFPGVALAVIL
CNTRHISDSVFLEAAKALTSQLTDEELAQGRLYPPLANIQEVSINIAIKVTEYLYANKMA
FRYPEPEDKAKYVKERTWRSEYDSLLPDVYEWPESASSPPVITE

Sequence length

584

Interactions

View interactions

	KEGG		Reactome
	Pyruvate metabolism Carbon metabolism		Citric acid cycle (TCA cycle)

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Schizophrenia	Schizophrenia	rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346 View all (12 more)	17258816

Show/Hide Text Mining Associations (18)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenoma	Associate	20664702
Alzheimer Disease	Stimulate	27845782
Carcinogenesis	Associate	27166188
Carcinoma Hepatocellular	Associate	40159482
Chromosome 7 monosomy	Inhibit	6576816
Epilepsy Idiopathic Generalized	Associate	15532013, 16190936
Glioblastoma	Associate	27166188
Glioma	Associate	27166188
Heart Failure	Inhibit	27406740
Leukemia	Associate	19066393
Lewy Body Disease	Associate	26627638
Lymphatic Metastasis	Stimulate	32218701
Mitochondrial Diseases	Associate	18332166
Myelodysplastic Syndromes	Associate	6576816
Neoplasms	Associate	26008970, 32218701
Rheumatic Heart Disease	Associate	24738046
Seizures	Associate	15532013
Squamous Cell Carcinoma of Head and Neck	Stimulate	32218701

ME2 (malic enzyme 2)