Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	4176
Gene name	Minichromosome maintenance complex component 7
Gene symbol	MCM7
Synonyms (NCBI Gene)	CDC47MCM2P1.1-MCM3P1CDC47P85MCMPNAS146PPP1R104
Chromosome	7
Chromosome location	7q22.1
Summary	The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component

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miRTarBase ID	miRNA	Experiments	Reference
MIRT016521	hsa-miR-193b-3p	Proteomics	21512034
MIRT016521	hsa-miR-193b-3p	Microarray	20304954
MIRT022853	hsa-miR-124-3p	Proteomics;Microarray	18668037
MIRT023890	hsa-miR-1-3p	Proteomics	18668040
MIRT025469	hsa-miR-34a-5p	Proteomics	21566225
MIRT025469	hsa-miR-34a-5p	Proteomics	21566225
MIRT052320	hsa-let-7b-5p	CLASH	23622248
MIRT049815	hsa-miR-92a-3p	CLASH	23622248
MIRT048095	hsa-miR-197-3p	CLASH	23622248
MIRT046710	hsa-miR-222-3p	CLASH	23622248
MIRT042002	hsa-miR-484	CLASH	23622248
MIRT041105	hsa-miR-503-5p	CLASH	23622248
MIRT038750	hsa-miR-93-3p	CLASH	23622248
MIRT035789	hsa-miR-1914-5p	CLASH	23622248
MIRT052674	hsa-miR-1260b	CLASH	23622248
MIRT509436	hsa-miR-583	PAR-CLIP	20371350
MIRT509435	hsa-miR-519a-3p	PAR-CLIP	20371350
MIRT509434	hsa-miR-519b-3p	PAR-CLIP	20371350
MIRT509433	hsa-miR-519c-3p	PAR-CLIP	20371350
MIRT509432	hsa-miR-302a-3p	PAR-CLIP	20371350
MIRT509431	hsa-miR-302b-3p	PAR-CLIP	20371350
MIRT509430	hsa-miR-302c-3p	PAR-CLIP	20371350
MIRT509429	hsa-miR-302d-3p	PAR-CLIP	20371350
MIRT509428	hsa-miR-302e	PAR-CLIP	20371350
MIRT509427	hsa-miR-372-3p	PAR-CLIP	20371350
MIRT509426	hsa-miR-373-3p	PAR-CLIP	20371350
MIRT509425	hsa-miR-520a-3p	PAR-CLIP	20371350
MIRT509424	hsa-miR-520b	PAR-CLIP	20371350
MIRT509423	hsa-miR-520c-3p	PAR-CLIP	20371350
MIRT509422	hsa-miR-520d-3p	PAR-CLIP	20371350
MIRT509421	hsa-miR-520e	PAR-CLIP	20371350
MIRT509420	hsa-miR-548p	PAR-CLIP	20371350
MIRT509419	hsa-miR-6085	PAR-CLIP	20371350
MIRT509418	hsa-miR-6813-5p	PAR-CLIP	20371350
MIRT509417	hsa-miR-6871-5p	PAR-CLIP	20371350
MIRT509416	hsa-miR-3184-5p	PAR-CLIP	20371350
MIRT509415	hsa-miR-423-5p	PAR-CLIP	20371350
MIRT509414	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT509413	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT509412	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT509411	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT509410	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT509409	hsa-miR-107	PAR-CLIP	20371350
MIRT509408	hsa-miR-4268	PAR-CLIP	20371350
MIRT509407	hsa-miR-6878-5p	PAR-CLIP	20371350
MIRT509406	hsa-miR-6731-5p	PAR-CLIP	20371350
MIRT509405	hsa-miR-8085	PAR-CLIP	20371350
MIRT509404	hsa-miR-4283	PAR-CLIP	20371350
MIRT509403	hsa-miR-3944-5p	PAR-CLIP	20371350
MIRT509401	hsa-miR-30c-1-3p	PAR-CLIP	20371350
MIRT509400	hsa-miR-30c-2-3p	PAR-CLIP	20371350
MIRT509399	hsa-miR-6788-5p	PAR-CLIP	20371350
MIRT509436	hsa-miR-583	PAR-CLIP	20371350
MIRT509435	hsa-miR-519a-3p	PAR-CLIP	20371350
MIRT509434	hsa-miR-519b-3p	PAR-CLIP	20371350
MIRT509433	hsa-miR-519c-3p	PAR-CLIP	20371350
MIRT509432	hsa-miR-302a-3p	PAR-CLIP	20371350
MIRT509431	hsa-miR-302b-3p	PAR-CLIP	20371350
MIRT509430	hsa-miR-302c-3p	PAR-CLIP	20371350
MIRT509429	hsa-miR-302d-3p	PAR-CLIP	20371350
MIRT509428	hsa-miR-302e	PAR-CLIP	20371350
MIRT509427	hsa-miR-372-3p	PAR-CLIP	20371350
MIRT509426	hsa-miR-373-3p	PAR-CLIP	20371350
MIRT509425	hsa-miR-520a-3p	PAR-CLIP	20371350
MIRT509424	hsa-miR-520b	PAR-CLIP	20371350
MIRT509423	hsa-miR-520c-3p	PAR-CLIP	20371350
MIRT509422	hsa-miR-520d-3p	PAR-CLIP	20371350
MIRT509421	hsa-miR-520e	PAR-CLIP	20371350
MIRT509420	hsa-miR-548p	PAR-CLIP	20371350
MIRT509419	hsa-miR-6085	PAR-CLIP	20371350
MIRT509418	hsa-miR-6813-5p	PAR-CLIP	20371350
MIRT509417	hsa-miR-6871-5p	PAR-CLIP	20371350
MIRT509416	hsa-miR-3184-5p	PAR-CLIP	20371350
MIRT509415	hsa-miR-423-5p	PAR-CLIP	20371350
MIRT509414	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT509413	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT509412	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT509411	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT509410	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT509409	hsa-miR-107	PAR-CLIP	20371350
MIRT509408	hsa-miR-4268	PAR-CLIP	20371350
MIRT509407	hsa-miR-6878-5p	PAR-CLIP	20371350
MIRT509406	hsa-miR-6731-5p	PAR-CLIP	20371350
MIRT509405	hsa-miR-8085	PAR-CLIP	20371350
MIRT509404	hsa-miR-4283	PAR-CLIP	20371350
MIRT509403	hsa-miR-3944-5p	PAR-CLIP	20371350
MIRT509402	hsa-miR-4766-3p	PAR-CLIP	20371350
MIRT509401	hsa-miR-30c-1-3p	PAR-CLIP	20371350
MIRT509400	hsa-miR-30c-2-3p	PAR-CLIP	20371350
MIRT509399	hsa-miR-6788-5p	PAR-CLIP	20371350
MIRT509436	hsa-miR-583	PAR-CLIP	21572407
MIRT509435	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT509434	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT509433	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT509432	hsa-miR-302a-3p	PAR-CLIP	21572407
MIRT509431	hsa-miR-302b-3p	PAR-CLIP	21572407
MIRT509430	hsa-miR-302c-3p	PAR-CLIP	21572407
MIRT509429	hsa-miR-302d-3p	PAR-CLIP	21572407
MIRT509428	hsa-miR-302e	PAR-CLIP	21572407
MIRT509427	hsa-miR-372-3p	PAR-CLIP	21572407
MIRT509426	hsa-miR-373-3p	PAR-CLIP	21572407
MIRT509425	hsa-miR-520a-3p	PAR-CLIP	21572407
MIRT509424	hsa-miR-520b	PAR-CLIP	21572407
MIRT509423	hsa-miR-520c-3p	PAR-CLIP	21572407
MIRT509422	hsa-miR-520d-3p	PAR-CLIP	21572407
MIRT509421	hsa-miR-520e	PAR-CLIP	21572407
MIRT509420	hsa-miR-548p	PAR-CLIP	21572407
MIRT509419	hsa-miR-6085	PAR-CLIP	21572407
MIRT509418	hsa-miR-6813-5p	PAR-CLIP	21572407
MIRT509417	hsa-miR-6871-5p	PAR-CLIP	21572407
MIRT509416	hsa-miR-3184-5p	PAR-CLIP	21572407
MIRT509415	hsa-miR-423-5p	PAR-CLIP	21572407
MIRT509414	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT509413	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT509412	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT509411	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT509410	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT509409	hsa-miR-107	PAR-CLIP	21572407
MIRT509408	hsa-miR-4268	PAR-CLIP	21572407
MIRT509407	hsa-miR-6878-5p	PAR-CLIP	21572407
MIRT509406	hsa-miR-6731-5p	PAR-CLIP	21572407
MIRT509405	hsa-miR-8085	PAR-CLIP	21572407
MIRT509404	hsa-miR-4283	PAR-CLIP	21572407
MIRT509403	hsa-miR-3944-5p	PAR-CLIP	21572407
MIRT509402	hsa-miR-4766-3p	PAR-CLIP	21572407
MIRT509401	hsa-miR-30c-1-3p	PAR-CLIP	21572407
MIRT509400	hsa-miR-30c-2-3p	PAR-CLIP	21572407
MIRT509399	hsa-miR-6788-5p	PAR-CLIP	21572407
MIRT509436	hsa-miR-583	PAR-CLIP	23446348
MIRT509435	hsa-miR-519a-3p	PAR-CLIP	23446348
MIRT509434	hsa-miR-519b-3p	PAR-CLIP	23446348
MIRT509433	hsa-miR-519c-3p	PAR-CLIP	23446348
MIRT509432	hsa-miR-302a-3p	PAR-CLIP	23446348
MIRT509431	hsa-miR-302b-3p	PAR-CLIP	23446348
MIRT509430	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT509429	hsa-miR-302d-3p	PAR-CLIP	23446348
MIRT509428	hsa-miR-302e	PAR-CLIP	23446348
MIRT509427	hsa-miR-372-3p	PAR-CLIP	23446348
MIRT509426	hsa-miR-373-3p	PAR-CLIP	23446348
MIRT509425	hsa-miR-520a-3p	PAR-CLIP	23446348
MIRT509424	hsa-miR-520b	PAR-CLIP	23446348
MIRT509423	hsa-miR-520c-3p	PAR-CLIP	23446348
MIRT509422	hsa-miR-520d-3p	PAR-CLIP	23446348
MIRT509421	hsa-miR-520e	PAR-CLIP	23446348
MIRT509420	hsa-miR-548p	PAR-CLIP	23446348
MIRT509419	hsa-miR-6085	PAR-CLIP	23446348
MIRT509418	hsa-miR-6813-5p	PAR-CLIP	23446348
MIRT509417	hsa-miR-6871-5p	PAR-CLIP	23446348
MIRT509416	hsa-miR-3184-5p	PAR-CLIP	23446348
MIRT509415	hsa-miR-423-5p	PAR-CLIP	23446348
MIRT509414	hsa-miR-548aj-5p	PAR-CLIP	23446348
MIRT509413	hsa-miR-548f-5p	PAR-CLIP	23446348
MIRT509412	hsa-miR-548g-5p	PAR-CLIP	23446348
MIRT509411	hsa-miR-548x-5p	PAR-CLIP	23446348
MIRT509410	hsa-miR-103a-3p	PAR-CLIP	23446348
MIRT509409	hsa-miR-107	PAR-CLIP	23446348
MIRT509408	hsa-miR-4268	PAR-CLIP	23446348
MIRT509407	hsa-miR-6878-5p	PAR-CLIP	23446348
MIRT509406	hsa-miR-6731-5p	PAR-CLIP	23446348
MIRT509405	hsa-miR-8085	PAR-CLIP	23446348
MIRT509404	hsa-miR-4283	PAR-CLIP	23446348
MIRT509403	hsa-miR-3944-5p	PAR-CLIP	23446348
MIRT509402	hsa-miR-4766-3p	PAR-CLIP	23446348
MIRT509401	hsa-miR-30c-1-3p	PAR-CLIP	23446348
MIRT509400	hsa-miR-30c-2-3p	PAR-CLIP	23446348
MIRT509399	hsa-miR-6788-5p	PAR-CLIP	23446348
MIRT509436	hsa-miR-583	PAR-CLIP	20371350
MIRT509435	hsa-miR-519a-3p	PAR-CLIP	20371350
MIRT509434	hsa-miR-519b-3p	PAR-CLIP	20371350
MIRT509433	hsa-miR-519c-3p	PAR-CLIP	20371350
MIRT509432	hsa-miR-302a-3p	PAR-CLIP	20371350
MIRT509431	hsa-miR-302b-3p	PAR-CLIP	20371350
MIRT509430	hsa-miR-302c-3p	PAR-CLIP	20371350
MIRT509429	hsa-miR-302d-3p	PAR-CLIP	20371350
MIRT509428	hsa-miR-302e	PAR-CLIP	20371350
MIRT509427	hsa-miR-372-3p	PAR-CLIP	20371350
MIRT509426	hsa-miR-373-3p	PAR-CLIP	20371350
MIRT509425	hsa-miR-520a-3p	PAR-CLIP	20371350
MIRT509424	hsa-miR-520b	PAR-CLIP	20371350
MIRT509423	hsa-miR-520c-3p	PAR-CLIP	20371350
MIRT509422	hsa-miR-520d-3p	PAR-CLIP	20371350
MIRT509421	hsa-miR-520e	PAR-CLIP	20371350
MIRT509420	hsa-miR-548p	PAR-CLIP	20371350
MIRT509419	hsa-miR-6085	PAR-CLIP	20371350
MIRT509418	hsa-miR-6813-5p	PAR-CLIP	20371350
MIRT509417	hsa-miR-6871-5p	PAR-CLIP	20371350
MIRT509416	hsa-miR-3184-5p	PAR-CLIP	20371350
MIRT509415	hsa-miR-423-5p	PAR-CLIP	20371350
MIRT509414	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT509413	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT509412	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT509411	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT509410	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT509409	hsa-miR-107	PAR-CLIP	20371350
MIRT509408	hsa-miR-4268	PAR-CLIP	20371350
MIRT509407	hsa-miR-6878-5p	PAR-CLIP	20371350
MIRT509406	hsa-miR-6731-5p	PAR-CLIP	20371350
MIRT509405	hsa-miR-8085	PAR-CLIP	20371350
MIRT509404	hsa-miR-4283	PAR-CLIP	20371350
MIRT509403	hsa-miR-3944-5p	PAR-CLIP	20371350
MIRT509401	hsa-miR-30c-1-3p	PAR-CLIP	20371350
MIRT509400	hsa-miR-30c-2-3p	PAR-CLIP	20371350
MIRT509399	hsa-miR-6788-5p	PAR-CLIP	20371350
MIRT509436	hsa-miR-583	PAR-CLIP	20371350
MIRT509435	hsa-miR-519a-3p	PAR-CLIP	20371350
MIRT509434	hsa-miR-519b-3p	PAR-CLIP	20371350
MIRT509433	hsa-miR-519c-3p	PAR-CLIP	20371350
MIRT509432	hsa-miR-302a-3p	PAR-CLIP	20371350
MIRT509431	hsa-miR-302b-3p	PAR-CLIP	20371350
MIRT509430	hsa-miR-302c-3p	PAR-CLIP	20371350
MIRT509429	hsa-miR-302d-3p	PAR-CLIP	20371350
MIRT509428	hsa-miR-302e	PAR-CLIP	20371350
MIRT509427	hsa-miR-372-3p	PAR-CLIP	20371350
MIRT509426	hsa-miR-373-3p	PAR-CLIP	20371350
MIRT509425	hsa-miR-520a-3p	PAR-CLIP	20371350
MIRT509424	hsa-miR-520b	PAR-CLIP	20371350
MIRT509423	hsa-miR-520c-3p	PAR-CLIP	20371350
MIRT509422	hsa-miR-520d-3p	PAR-CLIP	20371350
MIRT509421	hsa-miR-520e	PAR-CLIP	20371350
MIRT509420	hsa-miR-548p	PAR-CLIP	20371350
MIRT509419	hsa-miR-6085	PAR-CLIP	20371350
MIRT509418	hsa-miR-6813-5p	PAR-CLIP	20371350
MIRT509417	hsa-miR-6871-5p	PAR-CLIP	20371350
MIRT509416	hsa-miR-3184-5p	PAR-CLIP	20371350
MIRT509415	hsa-miR-423-5p	PAR-CLIP	20371350
MIRT509414	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT509413	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT509412	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT509411	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT509410	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT509409	hsa-miR-107	PAR-CLIP	20371350
MIRT509408	hsa-miR-4268	PAR-CLIP	20371350
MIRT509407	hsa-miR-6878-5p	PAR-CLIP	20371350
MIRT509406	hsa-miR-6731-5p	PAR-CLIP	20371350
MIRT509405	hsa-miR-8085	PAR-CLIP	20371350
MIRT509404	hsa-miR-4283	PAR-CLIP	20371350
MIRT509403	hsa-miR-3944-5p	PAR-CLIP	20371350
MIRT509402	hsa-miR-4766-3p	PAR-CLIP	20371350
MIRT509401	hsa-miR-30c-1-3p	PAR-CLIP	20371350
MIRT509400	hsa-miR-30c-2-3p	PAR-CLIP	20371350
MIRT509399	hsa-miR-6788-5p	PAR-CLIP	20371350
MIRT509436	hsa-miR-583	PAR-CLIP	21572407
MIRT509435	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT509434	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT509433	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT509432	hsa-miR-302a-3p	PAR-CLIP	21572407
MIRT509431	hsa-miR-302b-3p	PAR-CLIP	21572407
MIRT509430	hsa-miR-302c-3p	PAR-CLIP	21572407
MIRT509429	hsa-miR-302d-3p	PAR-CLIP	21572407
MIRT509428	hsa-miR-302e	PAR-CLIP	21572407
MIRT509427	hsa-miR-372-3p	PAR-CLIP	21572407
MIRT509426	hsa-miR-373-3p	PAR-CLIP	21572407
MIRT509425	hsa-miR-520a-3p	PAR-CLIP	21572407
MIRT509424	hsa-miR-520b	PAR-CLIP	21572407
MIRT509423	hsa-miR-520c-3p	PAR-CLIP	21572407
MIRT509422	hsa-miR-520d-3p	PAR-CLIP	21572407
MIRT509421	hsa-miR-520e	PAR-CLIP	21572407
MIRT509420	hsa-miR-548p	PAR-CLIP	21572407
MIRT509419	hsa-miR-6085	PAR-CLIP	21572407
MIRT509418	hsa-miR-6813-5p	PAR-CLIP	21572407
MIRT509417	hsa-miR-6871-5p	PAR-CLIP	21572407
MIRT509416	hsa-miR-3184-5p	PAR-CLIP	21572407
MIRT509415	hsa-miR-423-5p	PAR-CLIP	21572407
MIRT509414	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT509413	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT509412	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT509411	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT509410	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT509409	hsa-miR-107	PAR-CLIP	21572407
MIRT509408	hsa-miR-4268	PAR-CLIP	21572407
MIRT509407	hsa-miR-6878-5p	PAR-CLIP	21572407
MIRT509406	hsa-miR-6731-5p	PAR-CLIP	21572407
MIRT509405	hsa-miR-8085	PAR-CLIP	21572407
MIRT509404	hsa-miR-4283	PAR-CLIP	21572407
MIRT509403	hsa-miR-3944-5p	PAR-CLIP	21572407
MIRT509402	hsa-miR-4766-3p	PAR-CLIP	21572407
MIRT509401	hsa-miR-30c-1-3p	PAR-CLIP	21572407
MIRT509400	hsa-miR-30c-2-3p	PAR-CLIP	21572407
MIRT509399	hsa-miR-6788-5p	PAR-CLIP	21572407
MIRT509436	hsa-miR-583	PAR-CLIP	23446348
MIRT509435	hsa-miR-519a-3p	PAR-CLIP	23446348
MIRT509434	hsa-miR-519b-3p	PAR-CLIP	23446348
MIRT509433	hsa-miR-519c-3p	PAR-CLIP	23446348
MIRT509432	hsa-miR-302a-3p	PAR-CLIP	23446348
MIRT509431	hsa-miR-302b-3p	PAR-CLIP	23446348
MIRT509430	hsa-miR-302c-3p	PAR-CLIP	23446348
MIRT509429	hsa-miR-302d-3p	PAR-CLIP	23446348
MIRT509428	hsa-miR-302e	PAR-CLIP	23446348
MIRT509427	hsa-miR-372-3p	PAR-CLIP	23446348
MIRT509426	hsa-miR-373-3p	PAR-CLIP	23446348
MIRT509425	hsa-miR-520a-3p	PAR-CLIP	23446348
MIRT509424	hsa-miR-520b	PAR-CLIP	23446348
MIRT509423	hsa-miR-520c-3p	PAR-CLIP	23446348
MIRT509422	hsa-miR-520d-3p	PAR-CLIP	23446348
MIRT509421	hsa-miR-520e	PAR-CLIP	23446348
MIRT509420	hsa-miR-548p	PAR-CLIP	23446348
MIRT509419	hsa-miR-6085	PAR-CLIP	23446348
MIRT509418	hsa-miR-6813-5p	PAR-CLIP	23446348
MIRT509417	hsa-miR-6871-5p	PAR-CLIP	23446348
MIRT509416	hsa-miR-3184-5p	PAR-CLIP	23446348
MIRT509415	hsa-miR-423-5p	PAR-CLIP	23446348
MIRT509414	hsa-miR-548aj-5p	PAR-CLIP	23446348
MIRT509413	hsa-miR-548f-5p	PAR-CLIP	23446348
MIRT509412	hsa-miR-548g-5p	PAR-CLIP	23446348
MIRT509411	hsa-miR-548x-5p	PAR-CLIP	23446348
MIRT509410	hsa-miR-103a-3p	PAR-CLIP	23446348
MIRT509409	hsa-miR-107	PAR-CLIP	23446348
MIRT509408	hsa-miR-4268	PAR-CLIP	23446348
MIRT509407	hsa-miR-6878-5p	PAR-CLIP	23446348
MIRT509406	hsa-miR-6731-5p	PAR-CLIP	23446348
MIRT509405	hsa-miR-8085	PAR-CLIP	23446348
MIRT509404	hsa-miR-4283	PAR-CLIP	23446348
MIRT509403	hsa-miR-3944-5p	PAR-CLIP	23446348
MIRT509402	hsa-miR-4766-3p	PAR-CLIP	23446348
MIRT509401	hsa-miR-30c-1-3p	PAR-CLIP	23446348
MIRT509400	hsa-miR-30c-2-3p	PAR-CLIP	23446348
MIRT509399	hsa-miR-6788-5p	PAR-CLIP	23446348
MIRT1137782	hsa-miR-103a	CLIP-seq
MIRT1137783	hsa-miR-1283	CLIP-seq
MIRT1137784	hsa-miR-1915	CLIP-seq
MIRT1137785	hsa-miR-1972	CLIP-seq
MIRT1137786	hsa-miR-214	CLIP-seq
MIRT1137787	hsa-miR-296-3p	CLIP-seq
MIRT1137788	hsa-miR-302a	CLIP-seq
MIRT1137789	hsa-miR-302b	CLIP-seq
MIRT1137790	hsa-miR-302c	CLIP-seq
MIRT1137791	hsa-miR-302d	CLIP-seq
MIRT1137792	hsa-miR-3127-3p	CLIP-seq
MIRT1137793	hsa-miR-3184	CLIP-seq
MIRT1137794	hsa-miR-3619-5p	CLIP-seq
MIRT1137795	hsa-miR-3652	CLIP-seq
MIRT1137796	hsa-miR-3667-3p	CLIP-seq
MIRT1137797	hsa-miR-372	CLIP-seq
MIRT1137798	hsa-miR-373	CLIP-seq
MIRT1137799	hsa-miR-4430	CLIP-seq
MIRT1137800	hsa-miR-4530	CLIP-seq
MIRT1137801	hsa-miR-4684-3p	CLIP-seq
MIRT1137802	hsa-miR-4688	CLIP-seq
MIRT1137803	hsa-miR-4690-5p	CLIP-seq
MIRT1137804	hsa-miR-4751	CLIP-seq
MIRT1137805	hsa-miR-486-3p	CLIP-seq
MIRT1137806	hsa-miR-519a	CLIP-seq
MIRT1137807	hsa-miR-761	CLIP-seq
MIRT1137784	hsa-miR-1915	CLIP-seq
MIRT1137785	hsa-miR-1972	CLIP-seq
MIRT1137786	hsa-miR-214	CLIP-seq
MIRT1137787	hsa-miR-296-3p	CLIP-seq
MIRT1137792	hsa-miR-3127-3p	CLIP-seq
MIRT1137794	hsa-miR-3619-5p	CLIP-seq
MIRT1137800	hsa-miR-4530	CLIP-seq
MIRT1137802	hsa-miR-4688	CLIP-seq
MIRT2039121	hsa-miR-4749-3p	CLIP-seq
MIRT1137804	hsa-miR-4751	CLIP-seq
MIRT1137805	hsa-miR-486-3p	CLIP-seq
MIRT1137807	hsa-miR-761	CLIP-seq
MIRT1137782	hsa-miR-103a	CLIP-seq
MIRT1137783	hsa-miR-1283	CLIP-seq
MIRT1137785	hsa-miR-1972	CLIP-seq
MIRT1137786	hsa-miR-214	CLIP-seq
MIRT1137788	hsa-miR-302a	CLIP-seq
MIRT1137789	hsa-miR-302b	CLIP-seq
MIRT1137790	hsa-miR-302c	CLIP-seq
MIRT1137791	hsa-miR-302d	CLIP-seq
MIRT1137793	hsa-miR-3184	CLIP-seq
MIRT1137794	hsa-miR-3619-5p	CLIP-seq
MIRT1137796	hsa-miR-3667-3p	CLIP-seq
MIRT1137797	hsa-miR-372	CLIP-seq
MIRT1137798	hsa-miR-373	CLIP-seq
MIRT2269170	hsa-miR-3910	CLIP-seq
MIRT1137800	hsa-miR-4530	CLIP-seq
MIRT1137802	hsa-miR-4688	CLIP-seq
MIRT1137805	hsa-miR-486-3p	CLIP-seq
MIRT1137806	hsa-miR-519a	CLIP-seq
MIRT2269171	hsa-miR-548an	CLIP-seq
MIRT1137807	hsa-miR-761	CLIP-seq
MIRT1137784	hsa-miR-1915	CLIP-seq
MIRT1137785	hsa-miR-1972	CLIP-seq
MIRT1137786	hsa-miR-214	CLIP-seq
MIRT1137787	hsa-miR-296-3p	CLIP-seq
MIRT1137792	hsa-miR-3127-3p	CLIP-seq
MIRT1137794	hsa-miR-3619-5p	CLIP-seq
MIRT1137800	hsa-miR-4530	CLIP-seq
MIRT1137801	hsa-miR-4684-3p	CLIP-seq
MIRT1137802	hsa-miR-4688	CLIP-seq
MIRT2039121	hsa-miR-4749-3p	CLIP-seq
MIRT1137804	hsa-miR-4751	CLIP-seq
MIRT1137805	hsa-miR-486-3p	CLIP-seq
MIRT1137807	hsa-miR-761	CLIP-seq

Show/Hide all (4)

Transcription factor	Regulation	Reference
MSC	Repression	15213307
MYCN	Activation	17826980
MYCN	Unknown	15668898
TP53	Repression	15899946

Show/Hide all (46)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0000727	Process	Double-strand break repair via break-induced replication	IBA
GO:0000781	Component	Chromosome, telomeric region	HDA	19135898
GO:0000785	Component	Chromatin	TAS	8798650
GO:0003677	Function	DNA binding	IEA
GO:0003677	Function	DNA binding	TAS	15538388
GO:0003678	Function	DNA helicase activity	IDA	9305914, 25661590
GO:0003678	Function	DNA helicase activity	IEA
GO:0003678	Function	DNA helicase activity	IEA
GO:0003697	Function	Single-stranded DNA binding	IDA	25661590
GO:0003697	Function	Single-stranded DNA binding	IEA
GO:0003697	Function	Single-stranded DNA binding	ISS
GO:0004386	Function	Helicase activity	IEA
GO:0005515	Function	Protein binding	IPI	9705868, 10518787, 12364596, 15232106, 15538388, 15654075, 16289477, 16438930, 16899510, 16902406, 17296731, 17310990, 17314511, 19150984, 22540012, 23764002, 24299456, 25036637, 25416956, 26496610, 26871637, 28191891, 28514442, 31515488, 32296183, 32814053, 33654309, 33961781, 3527
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	21383955, 22474384
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005694	Component	Chromosome	IEA
GO:0005730	Component	Nucleolus	IDA	21383955
GO:0006260	Process	DNA replication	IDA	22474384
GO:0006260	Process	DNA replication	IEA
GO:0006260	Process	DNA replication	IEA
GO:0006260	Process	DNA replication	TAS	8798650
GO:0006270	Process	DNA replication initiation	IBA
GO:0006270	Process	DNA replication initiation	IEA
GO:0006271	Process	DNA strand elongation involved in DNA replication	IBA
GO:0006974	Process	DNA damage response	IMP	15538388
GO:0008283	Process	Cell population proliferation	IEA
GO:0009410	Process	Response to xenobiotic stimulus	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016787	Function	Hydrolase activity	IEA
GO:0016887	Function	ATP hydrolysis activity	IEA
GO:0017116	Function	Single-stranded DNA helicase activity	IBA
GO:0030174	Process	Regulation of DNA-templated DNA replication initiation	NAS	30069701
GO:0042325	Process	Regulation of phosphorylation	IMP	15538388
GO:0042555	Component	MCM complex	IBA
GO:0042555	Component	MCM complex	IDA	17296731, 25661590
GO:0042555	Component	MCM complex	IEA
GO:0042555	Component	MCM complex	IMP	15538388
GO:0042555	Component	MCM complex	IPI	22540012
GO:0071162	Component	CMG complex	IPI	22474384
GO:0071162	Component	CMG complex	ISS
GO:0071364	Process	Cellular response to epidermal growth factor stimulus	IEA
GO:0071466	Process	Cellular response to xenobiotic stimulus	IEA

MIM	HGNC	e!Ensembl
600592	6950	ENSG00000166508

P33993

Protein name

DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog) (P1.1-MCM3)

Protein function

Acts as a component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the mol

PDB

6XTX , 6XTY , 7PFO , 7PLO , 7W1Y , 7W68 , 8B9D , 8RWV , 8S09 , 8S0A , 8S0B , 8S0D , 8S0E , 8S0F , 8W0E , 8W0F , 8W0G , 8W0I , 9CAQ

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF14551	MCM_N	10 → 140	MCM N-terminal domain	Domain
PF17207	MCM_OB	148 → 281	MCM OB domain	Domain
PF00493	MCM	320 → 541	MCM P-loop domain	Domain
PF17855	MCM_lid	557 → 641	MCM AAA-lid domain	Domain

Sequence

MALKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYVDLDDVAEDDP
ELVDSICENARRYAKLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGMVR
SPQNQYPAELMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVA
TYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEH
SDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEA
HRIVKMNKSEDDESGAGELTREELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVG
GVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLR
DSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNA
RCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYV
HQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASKDATY
TSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADV
IFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRITFV

Sequence length

719

Interactions

View interactions

	KEGG		Reactome
	DNA replication Cell cycle		Activation of ATR in response to replication stress Assembly of the pre-replicative complex Orc1 removal from chromatin Activation of the pre-replicative complex Switching of origins to a post-replicative state

Show/Hide Causal Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Meier-Gorlin syndrome	Pathogenic	rs778583017, rs76705400, rs758105856, rs1054083917	RCV001527364 RCV001527379 RCV001527378 RCV001527363

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
MCM7-related disorder	Likely benign	rs149624106	RCV003915848

Show/Hide Text Mining Associations (60)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
ACTH Secreting Pituitary Adenoma	Associate	28432562
Adenocarcinoma	Associate	27476776
Adenocarcinoma of Lung	Associate	31074380, 31323040, 34996932, 37517032
Adenocarcinoma of Lung	Stimulate	32149133
Adenoma	Associate	28432562
Adrenal Insufficiency	Associate	33654309
Anus Neoplasms	Associate	18349847
Barrett Esophagus	Associate	27476776
Breast Neoplasms	Associate	32830194
Carcinogenesis	Associate	20648010, 22393390, 24416400, 26156831
Carcinoma Basal Cell	Stimulate	32830194
Carcinoma Hepatocellular	Associate	22393390, 24416400, 25393367, 28182015, 31011256, 32964028
Carcinoma Non Small Cell Lung	Associate	21619671, 24763826, 25045014, 27797825, 28465488
Carcinoma Pancreatic Ductal	Associate	15548371, 38423594
Carcinoma Renal Cell	Associate	37464398
Carcinoma Squamous Cell	Associate	27476776, 34609416, 36445337
Carcinoma Squamous Cell	Stimulate	31653153
Cleft Palate	Associate	34609416
Colorectal Neoplasms	Associate	30937307, 32612138, 34120619
Death	Associate	24416400
Desmoid disease hereditary	Associate	21478101
Endometrial Neoplasms	Associate	23028803
Esophageal Diseases	Associate	27476776
Esophageal Neoplasms	Associate	27476776
Glioblastoma	Stimulate	16619508
Glioma	Associate	25046975
Hepatitis B	Associate	22393390
Leiomyoma	Associate	22556343, 34449552
Leukemia Biphenotypic Acute	Associate	27351222
Leukemia Myeloid Acute	Associate	30480765
Lipodystrophy	Associate	33654309
Liver Neoplasms	Associate	21619671
Lung Diseases	Associate	21619671
Lung Neoplasms	Associate	25045014, 27797825, 28465488, 32596300, 35360518
Lymphatic Metastasis	Stimulate	19189662
Meier Gorlin syndrome	Associate	33654309
Meningioma	Stimulate	19877719
Neoplasm Invasiveness	Associate	23201130
Neoplasm Metastasis	Associate	19189662
Neoplasms	Associate	18349847, 20460506, 21523718, 21619671, 22838965, 23313748, 25046975, 28032719, 28182015, 28432562, 28540486, 31074380, 31234753, 32964028, 32989049, 34609416, 36061145 View all (2 more)
Neoplasms Cystic Mucinous and Serous	Stimulate	21076460
NOG Related Symphalangism Spectrum Disorder	Associate	32360491
Oculocutaneous albinism type 2	Associate	25046975
Ovarian Neoplasms	Associate	21076460
Pancreatic Neoplasms	Associate	25502777, 27695057
Precancerous Conditions	Associate	19189662, 27476776
Progeroid syndrome neonatal	Associate	33654309
Prostatic Neoplasms	Associate	18676839, 34573332
Prostatitis	Stimulate	18676839
Retinal Dysplasia	Associate	18414413, 27476776
Sarcoma Synovial	Associate	17464317
Small Cell Lung Carcinoma	Associate	25045014
Squamous Cell Carcinoma of Head and Neck	Associate	19189662, 28032719
Squamous Intraepithelial Lesions	Associate	31653153
Stomach Diseases	Associate	28540486
Stomach Neoplasms	Associate	18328430, 28540486
Thyroid Neoplasms	Associate	37864896
Urethral Neoplasms	Associate	23201130
Urinary Bladder Neoplasms	Associate	18414413, 21619671, 23201130, 26966728
Uterine Cervical Neoplasms	Associate	23874974

MCM7 (minichromosome maintenance complex component 7)