Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	4155
Gene name Gene Name - the full gene name approved by the HGNC.	Myelin basic protein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MBP
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	18
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	18q23
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs ar

Show/Hide all(310)

miRTarBase ID	miRNA	Experiments	Reference
MIRT440269	hsa-miR-127-5p	HITS-CLIP	24374217
MIRT440269	hsa-miR-127-5p	HITS-CLIP	24374217
MIRT734679	hsa-miR-665	RNA-seq, qRT-PCR, Immunocytochemistry (ICC), ELISA	31775315
MIRT738748	hsa-miR-759	HITS-CLIP	33718276
MIRT1136004	hsa-miR-1257	CLIP-seq
MIRT1136005	hsa-miR-3192	CLIP-seq
MIRT1136006	hsa-miR-3689a-3p	CLIP-seq
MIRT1136007	hsa-miR-3689c	CLIP-seq
MIRT1136008	hsa-miR-4537	CLIP-seq
MIRT1136009	hsa-miR-4728-5p	CLIP-seq
MIRT1136010	hsa-miR-1184	CLIP-seq
MIRT1136011	hsa-miR-1258	CLIP-seq
MIRT1136012	hsa-miR-125a-5p	CLIP-seq
MIRT1136013	hsa-miR-125b	CLIP-seq
MIRT1136014	hsa-miR-1294	CLIP-seq
MIRT1136015	hsa-miR-1296	CLIP-seq
MIRT1136016	hsa-miR-1301	CLIP-seq
MIRT1136017	hsa-miR-1321	CLIP-seq
MIRT1136018	hsa-miR-134	CLIP-seq
MIRT1136019	hsa-miR-188-5p	CLIP-seq
MIRT1136020	hsa-miR-2467-3p	CLIP-seq
MIRT1136021	hsa-miR-2909	CLIP-seq
MIRT1136022	hsa-miR-3118	CLIP-seq
MIRT1136023	hsa-miR-3120-3p	CLIP-seq
MIRT1136024	hsa-miR-3125	CLIP-seq
MIRT1136025	hsa-miR-3136-5p	CLIP-seq
MIRT1136026	hsa-miR-3148	CLIP-seq
MIRT1136027	hsa-miR-3158-5p	CLIP-seq
MIRT1136028	hsa-miR-3162-5p	CLIP-seq
MIRT1136029	hsa-miR-3163	CLIP-seq
MIRT1136030	hsa-miR-329	CLIP-seq
MIRT1136031	hsa-miR-362-3p	CLIP-seq
MIRT1136032	hsa-miR-3672	CLIP-seq
MIRT1136033	hsa-miR-3678-3p	CLIP-seq
MIRT1136034	hsa-miR-3688-3p	CLIP-seq
MIRT1136035	hsa-miR-383	CLIP-seq
MIRT1136036	hsa-miR-3915	CLIP-seq
MIRT1136037	hsa-miR-3916	CLIP-seq
MIRT1136038	hsa-miR-3928	CLIP-seq
MIRT1136039	hsa-miR-4269	CLIP-seq
MIRT738746	hsa-miR-4282	CLIP-seq
MIRT1136040	hsa-miR-4316	CLIP-seq
MIRT1136041	hsa-miR-4319	CLIP-seq
MIRT1136042	hsa-miR-4324	CLIP-seq
MIRT1136043	hsa-miR-4418	CLIP-seq
MIRT1136044	hsa-miR-4434	CLIP-seq
MIRT1136045	hsa-miR-4436b-3p	CLIP-seq
MIRT1136046	hsa-miR-4439	CLIP-seq
MIRT1136047	hsa-miR-4455	CLIP-seq
MIRT1136048	hsa-miR-4513	CLIP-seq
MIRT1136049	hsa-miR-4514	CLIP-seq
MIRT1136050	hsa-miR-4516	CLIP-seq
MIRT1136051	hsa-miR-4532	CLIP-seq
MIRT1136052	hsa-miR-4660	CLIP-seq
MIRT1136053	hsa-miR-4692	CLIP-seq
MIRT1136054	hsa-miR-4704-3p	CLIP-seq
MIRT1136055	hsa-miR-4724-5p	CLIP-seq
MIRT1136056	hsa-miR-4725-5p	CLIP-seq
MIRT1136057	hsa-miR-4731-3p	CLIP-seq
MIRT1136058	hsa-miR-4739	CLIP-seq
MIRT1136059	hsa-miR-4742-5p	CLIP-seq
MIRT1136060	hsa-miR-4756-5p	CLIP-seq
MIRT1136061	hsa-miR-4761-3p	CLIP-seq
MIRT1136062	hsa-miR-4772-5p	CLIP-seq
MIRT1136063	hsa-miR-4777-5p	CLIP-seq
MIRT1136064	hsa-miR-4780	CLIP-seq
MIRT1136065	hsa-miR-4801	CLIP-seq
MIRT1136066	hsa-miR-485-3p	CLIP-seq
MIRT1136067	hsa-miR-504	CLIP-seq
MIRT1136068	hsa-miR-5047	CLIP-seq
MIRT1136069	hsa-miR-509-3-5p	CLIP-seq
MIRT1136070	hsa-miR-509-5p	CLIP-seq
MIRT1136071	hsa-miR-518d-5p	CLIP-seq
MIRT1136072	hsa-miR-519b-5p	CLIP-seq
MIRT1136073	hsa-miR-519c-5p	CLIP-seq
MIRT1136074	hsa-miR-520c-5p	CLIP-seq
MIRT1136075	hsa-miR-526a	CLIP-seq
MIRT1136076	hsa-miR-548c-3p	CLIP-seq
MIRT1136077	hsa-miR-583	CLIP-seq
MIRT1136078	hsa-miR-609	CLIP-seq
MIRT1136079	hsa-miR-623	CLIP-seq
MIRT1551184	hsa-miR-1200	CLIP-seq
MIRT1136042	hsa-miR-4324	CLIP-seq
MIRT1551185	hsa-miR-544b	CLIP-seq
MIRT1551184	hsa-miR-1200	CLIP-seq
MIRT2038661	hsa-miR-1303	CLIP-seq
MIRT2038662	hsa-miR-136	CLIP-seq
MIRT2038663	hsa-miR-1587	CLIP-seq
MIRT2038664	hsa-miR-22	CLIP-seq
MIRT1136020	hsa-miR-2467-3p	CLIP-seq
MIRT1136027	hsa-miR-3158-5p	CLIP-seq
MIRT2038665	hsa-miR-3160-5p	CLIP-seq
MIRT2038666	hsa-miR-3529	CLIP-seq
MIRT1136033	hsa-miR-3678-3p	CLIP-seq
MIRT2038667	hsa-miR-379	CLIP-seq
MIRT2038668	hsa-miR-3925-3p	CLIP-seq
MIRT2038669	hsa-miR-4277	CLIP-seq
MIRT2038670	hsa-miR-4299	CLIP-seq
MIRT2038671	hsa-miR-4437	CLIP-seq
MIRT2038672	hsa-miR-4451	CLIP-seq
MIRT2038673	hsa-miR-4650-3p	CLIP-seq
MIRT2038674	hsa-miR-4659a-3p	CLIP-seq
MIRT2038675	hsa-miR-4659b-3p	CLIP-seq
MIRT2038676	hsa-miR-4674	CLIP-seq
MIRT2038677	hsa-miR-4691-3p	CLIP-seq
MIRT1136054	hsa-miR-4704-3p	CLIP-seq
MIRT1136009	hsa-miR-4728-5p	CLIP-seq
MIRT2038678	hsa-miR-515-5p	CLIP-seq
MIRT2038679	hsa-miR-586	CLIP-seq
MIRT2038680	hsa-miR-635	CLIP-seq
MIRT2038681	hsa-miR-766	CLIP-seq
MIRT2038682	hsa-miR-877	CLIP-seq
MIRT2038683	hsa-miR-942	CLIP-seq
MIRT2268574	hsa-miR-1197	CLIP-seq
MIRT1551184	hsa-miR-1200	CLIP-seq
MIRT2268575	hsa-miR-1207-3p	CLIP-seq
MIRT2268576	hsa-miR-1236	CLIP-seq
MIRT2268577	hsa-miR-1273d	CLIP-seq
MIRT2268578	hsa-miR-128	CLIP-seq
MIRT2268579	hsa-miR-132	CLIP-seq
MIRT2268580	hsa-miR-1323	CLIP-seq
MIRT1136018	hsa-miR-134	CLIP-seq
MIRT2268581	hsa-miR-138	CLIP-seq
MIRT2268582	hsa-miR-140-3p	CLIP-seq
MIRT2038663	hsa-miR-1587	CLIP-seq
MIRT2268583	hsa-miR-181a	CLIP-seq
MIRT2268584	hsa-miR-181b	CLIP-seq
MIRT2268585	hsa-miR-181c	CLIP-seq
MIRT2268586	hsa-miR-181d	CLIP-seq
MIRT2268587	hsa-miR-1972	CLIP-seq
MIRT2268588	hsa-miR-199a-5p	CLIP-seq
MIRT2268589	hsa-miR-199b-5p	CLIP-seq
MIRT2268590	hsa-miR-212	CLIP-seq
MIRT2268591	hsa-miR-216a	CLIP-seq
MIRT1136020	hsa-miR-2467-3p	CLIP-seq
MIRT2268592	hsa-miR-3065-5p	CLIP-seq
MIRT1136022	hsa-miR-3118	CLIP-seq
MIRT1136023	hsa-miR-3120-3p	CLIP-seq
MIRT1136024	hsa-miR-3125	CLIP-seq
MIRT2268593	hsa-miR-3130-3p	CLIP-seq
MIRT2268594	hsa-miR-3130-5p	CLIP-seq
MIRT1136025	hsa-miR-3136-5p	CLIP-seq
MIRT1136026	hsa-miR-3148	CLIP-seq
MIRT1136027	hsa-miR-3158-5p	CLIP-seq
MIRT2268595	hsa-miR-338-3p	CLIP-seq
MIRT2038666	hsa-miR-3529	CLIP-seq
MIRT1136032	hsa-miR-3672	CLIP-seq
MIRT1136033	hsa-miR-3678-3p	CLIP-seq
MIRT2038667	hsa-miR-379	CLIP-seq
MIRT1136037	hsa-miR-3916	CLIP-seq
MIRT2268596	hsa-miR-3919	CLIP-seq
MIRT2038668	hsa-miR-3925-3p	CLIP-seq
MIRT2268597	hsa-miR-3925-5p	CLIP-seq
MIRT2268598	hsa-miR-3975	CLIP-seq
MIRT2268599	hsa-miR-421	CLIP-seq
MIRT2268600	hsa-miR-4262	CLIP-seq
MIRT2268601	hsa-miR-4265	CLIP-seq
MIRT1136039	hsa-miR-4269	CLIP-seq
MIRT2268602	hsa-miR-4296	CLIP-seq
MIRT2038670	hsa-miR-4299	CLIP-seq
MIRT2268603	hsa-miR-4322	CLIP-seq
MIRT1136042	hsa-miR-4324	CLIP-seq
MIRT2268604	hsa-miR-4330	CLIP-seq
MIRT2268605	hsa-miR-4417	CLIP-seq
MIRT2268606	hsa-miR-4436b-5p	CLIP-seq
MIRT2038671	hsa-miR-4437	CLIP-seq
MIRT1136046	hsa-miR-4439	CLIP-seq
MIRT2038672	hsa-miR-4451	CLIP-seq
MIRT2268607	hsa-miR-4482	CLIP-seq
MIRT2268608	hsa-miR-4484	CLIP-seq
MIRT2268609	hsa-miR-4492	CLIP-seq
MIRT2268610	hsa-miR-4498	CLIP-seq
MIRT1136048	hsa-miR-4513	CLIP-seq
MIRT1136049	hsa-miR-4514	CLIP-seq
MIRT2268611	hsa-miR-451b	CLIP-seq
MIRT2268612	hsa-miR-4530	CLIP-seq
MIRT2038673	hsa-miR-4650-3p	CLIP-seq
MIRT2268613	hsa-miR-4650-5p	CLIP-seq
MIRT2268614	hsa-miR-4656	CLIP-seq
MIRT2038676	hsa-miR-4674	CLIP-seq
MIRT2268615	hsa-miR-4675	CLIP-seq
MIRT2038677	hsa-miR-4691-3p	CLIP-seq
MIRT1136053	hsa-miR-4692	CLIP-seq
MIRT2268616	hsa-miR-4712-5p	CLIP-seq
MIRT2268617	hsa-miR-4718	CLIP-seq
MIRT2268618	hsa-miR-4733-5p	CLIP-seq
MIRT2268619	hsa-miR-4741	CLIP-seq
MIRT2268620	hsa-miR-4753-3p	CLIP-seq
MIRT2268621	hsa-miR-4768-5p	CLIP-seq
MIRT2268622	hsa-miR-4793-3p	CLIP-seq
MIRT2268623	hsa-miR-508-5p	CLIP-seq
MIRT2268624	hsa-miR-510	CLIP-seq
MIRT2038678	hsa-miR-515-5p	CLIP-seq
MIRT2268625	hsa-miR-544	CLIP-seq
MIRT1551185	hsa-miR-544b	CLIP-seq
MIRT2268626	hsa-miR-548a-3p	CLIP-seq
MIRT2268627	hsa-miR-548ad	CLIP-seq
MIRT2268628	hsa-miR-548an	CLIP-seq
MIRT2268629	hsa-miR-548e	CLIP-seq
MIRT2268630	hsa-miR-548f	CLIP-seq
MIRT2268631	hsa-miR-548o	CLIP-seq
MIRT2268632	hsa-miR-582-3p	CLIP-seq
MIRT2038679	hsa-miR-586	CLIP-seq
MIRT2268633	hsa-miR-597	CLIP-seq
MIRT2268634	hsa-miR-634	CLIP-seq
MIRT2038680	hsa-miR-635	CLIP-seq
MIRT2268635	hsa-miR-642b	CLIP-seq
MIRT2268636	hsa-miR-646	CLIP-seq
MIRT2268637	hsa-miR-653	CLIP-seq
MIRT2268638	hsa-miR-662	CLIP-seq
MIRT2268639	hsa-miR-762	CLIP-seq
MIRT2038681	hsa-miR-766	CLIP-seq
MIRT2268640	hsa-miR-769-5p	CLIP-seq
MIRT2268641	hsa-miR-770-5p	CLIP-seq
MIRT2038682	hsa-miR-877	CLIP-seq
MIRT1551184	hsa-miR-1200	CLIP-seq
MIRT2390681	hsa-miR-1266	CLIP-seq
MIRT2268577	hsa-miR-1273d	CLIP-seq
MIRT2390682	hsa-miR-1287	CLIP-seq
MIRT2038661	hsa-miR-1303	CLIP-seq
MIRT2268580	hsa-miR-1323	CLIP-seq
MIRT2038663	hsa-miR-1587	CLIP-seq
MIRT2268583	hsa-miR-181a	CLIP-seq
MIRT2268584	hsa-miR-181b	CLIP-seq
MIRT2268585	hsa-miR-181c	CLIP-seq
MIRT2268586	hsa-miR-181d	CLIP-seq
MIRT2390683	hsa-miR-185	CLIP-seq
MIRT1136019	hsa-miR-188-5p	CLIP-seq
MIRT2268588	hsa-miR-199a-5p	CLIP-seq
MIRT2268589	hsa-miR-199b-5p	CLIP-seq
MIRT2038664	hsa-miR-22	CLIP-seq
MIRT2268594	hsa-miR-3130-5p	CLIP-seq
MIRT2390684	hsa-miR-3135b	CLIP-seq
MIRT1136026	hsa-miR-3148	CLIP-seq
MIRT1136030	hsa-miR-329	CLIP-seq
MIRT1136031	hsa-miR-362-3p	CLIP-seq
MIRT2038668	hsa-miR-3925-3p	CLIP-seq
MIRT2268600	hsa-miR-4262	CLIP-seq
MIRT2390685	hsa-miR-4270	CLIP-seq
MIRT2390686	hsa-miR-4291	CLIP-seq
MIRT2038670	hsa-miR-4299	CLIP-seq
MIRT2390687	hsa-miR-4306	CLIP-seq
MIRT2390688	hsa-miR-4310	CLIP-seq
MIRT1136042	hsa-miR-4324	CLIP-seq
MIRT2038671	hsa-miR-4437	CLIP-seq
MIRT2390689	hsa-miR-4441	CLIP-seq
MIRT2268607	hsa-miR-4482	CLIP-seq
MIRT2390690	hsa-miR-4518	CLIP-seq
MIRT2268612	hsa-miR-4530	CLIP-seq
MIRT2390691	hsa-miR-4644	CLIP-seq
MIRT2038676	hsa-miR-4674	CLIP-seq
MIRT2038677	hsa-miR-4691-3p	CLIP-seq
MIRT2268617	hsa-miR-4718	CLIP-seq
MIRT1136056	hsa-miR-4725-5p	CLIP-seq
MIRT2390692	hsa-miR-4738-5p	CLIP-seq
MIRT2390693	hsa-miR-498	CLIP-seq
MIRT1136067	hsa-miR-504	CLIP-seq
MIRT2268623	hsa-miR-508-5p	CLIP-seq
MIRT2268624	hsa-miR-510	CLIP-seq
MIRT2038678	hsa-miR-515-5p	CLIP-seq
MIRT1551185	hsa-miR-544b	CLIP-seq
MIRT2268626	hsa-miR-548a-3p	CLIP-seq
MIRT2268627	hsa-miR-548ad	CLIP-seq
MIRT2268629	hsa-miR-548e	CLIP-seq
MIRT2268630	hsa-miR-548f	CLIP-seq
MIRT2268631	hsa-miR-548o	CLIP-seq
MIRT2268632	hsa-miR-582-3p	CLIP-seq
MIRT2038679	hsa-miR-586	CLIP-seq
MIRT2390694	hsa-miR-607	CLIP-seq
MIRT2038680	hsa-miR-635	CLIP-seq
MIRT2268636	hsa-miR-646	CLIP-seq
MIRT2390695	hsa-miR-760	CLIP-seq
MIRT2038681	hsa-miR-766	CLIP-seq
MIRT2453810	hsa-miR-1305	CLIP-seq
MIRT2268588	hsa-miR-199a-5p	CLIP-seq
MIRT2268589	hsa-miR-199b-5p	CLIP-seq
MIRT1136006	hsa-miR-3689a-3p	CLIP-seq
MIRT1136007	hsa-miR-3689c	CLIP-seq
MIRT2453811	hsa-miR-4325	CLIP-seq
MIRT2453812	hsa-miR-4635	CLIP-seq
MIRT1136009	hsa-miR-4728-5p	CLIP-seq
MIRT2453813	hsa-miR-526b	CLIP-seq
MIRT2453814	hsa-miR-578	CLIP-seq
MIRT2268633	hsa-miR-597	CLIP-seq
MIRT2453815	hsa-miR-668	CLIP-seq
MIRT2453816	hsa-miR-765	CLIP-seq
MIRT2453810	hsa-miR-1305	CLIP-seq
MIRT2268588	hsa-miR-199a-5p	CLIP-seq
MIRT2268589	hsa-miR-199b-5p	CLIP-seq
MIRT2268633	hsa-miR-597	CLIP-seq
MIRT2453815	hsa-miR-668	CLIP-seq
MIRT2390681	hsa-miR-1266	CLIP-seq
MIRT1136017	hsa-miR-1321	CLIP-seq
MIRT2568067	hsa-miR-3664-3p	CLIP-seq
MIRT2390685	hsa-miR-4270	CLIP-seq
MIRT2568068	hsa-miR-4278	CLIP-seq
MIRT2390689	hsa-miR-4441	CLIP-seq
MIRT2390690	hsa-miR-4518	CLIP-seq
MIRT2568069	hsa-miR-4686	CLIP-seq
MIRT1136009	hsa-miR-4728-5p	CLIP-seq
MIRT2568070	hsa-miR-4735-5p	CLIP-seq
MIRT1136058	hsa-miR-4739	CLIP-seq
MIRT1136060	hsa-miR-4756-5p	CLIP-seq
MIRT2568071	hsa-miR-767-3p	CLIP-seq
MIRT2038683	hsa-miR-942	CLIP-seq
MIRT2568068	hsa-miR-4278	CLIP-seq
MIRT2568069	hsa-miR-4686	CLIP-seq
MIRT1136009	hsa-miR-4728-5p	CLIP-seq
MIRT2568070	hsa-miR-4735-5p	CLIP-seq
MIRT2568071	hsa-miR-767-3p	CLIP-seq

Transcription factors

Show/Hide all(3)

Transcription factor	Regulation	Reference
NF1	Unknown	9765312
NFIB	Activation	1699939
SOX10	Unknown	11734543

Show/Hide all(29)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000165	Process	MAPK cascade	IDA	22524708
GO:0002020	Function	Protease binding	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 28298427, 31515488
GO:0005516	Function	Calmodulin binding	IPI	19855925
GO:0005634	Component	Nucleus	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0006955	Process	Immune response	TAS	7504278
GO:0007268	Process	Chemical synaptic transmission	TAS	2434243
GO:0007417	Process	Central nervous system development	TAS	2434243
GO:0007605	Process	Sensory perception of sound	IEA
GO:0008366	Process	Axon ensheathment	TAS	2434243
GO:0009636	Process	Response to toxic substance	IEA
GO:0009986	Component	Cell surface	ISS
GO:0019911	Function	Structural constituent of myelin sheath	IBA	21873635
GO:0021762	Process	Substantia nigra development	HEP	22926577
GO:0032755	Process	Positive regulation of interleukin-6 production	IDA	22524708
GO:0032991	Component	Protein-containing complex	IDA	19855925
GO:0033269	Component	Internode region of axon	IBA	21873635
GO:0034115	Process	Negative regulation of heterotypic cell-cell adhesion	IDA	22524708
GO:0035633	Process	Maintenance of blood-brain barrier	IDA	22524708
GO:0042552	Process	Myelination	IBA	21873635
GO:0043025	Component	Neuronal cell body	IBA	21873635
GO:0043209	Component	Myelin sheath	IDA	19855925
GO:0043218	Component	Compact myelin	IBA	21873635
GO:0045202	Component	Synapse	IEA
GO:0061024	Process	Membrane organization	IEA
GO:0071944	Component	Cell periphery	IBA	21873635
GO:1904685	Process	Positive regulation of metalloendopeptidase activity	IDA	22524708
GO:2000343	Process	Positive regulation of chemokine (C-X-C motif) ligand 2 production	IDA	22524708

MIM	HGNC	e!Ensembl
159430	6925	ENSG00000197971

Protein

UniProt ID

P02686

Protein name

Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein)

Protein function

The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important

PDB

1BX2 , 1FV1 , 1HQR , 1K2D , 1YMM , 1ZGL

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01669	Myelin_MBP	149 → 304	Myelin basic protein	Family

Tissue specificity

TISSUE SPECIFICITY: MBP isoforms are found in both the central and the peripheral nervous system, whereas Golli-MBP isoforms are expressed in fetal thymus, spleen and spinal cord, as well as in cell lines derived from the immune system. {ECO:0000269|PubMe

Sequence

MGNHAGKRELNAEKASTNSETNRGESEKKRNLGELSRTTSEDNEVFGEADANQNNGTSSQ
DTAVTDSKRTADPKNAWQDAHPADPGSRPHLIRLFSRDAPGREDNTFKDRPSESDELQTI
QEDSAATSESLDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFG
GDRGAPKRGSGKDSHHPARTAHYGSLPQKSHGRTQDENPVVHFFKNIVTPRTPPPSQGKG
RGLSLSRFSWGAEGQRPGFGYGGRASDYKSAHKGFKGVDAQGTLSKIFKLGGRDSRSGSP
MARR

Sequence length

304

Interactions

View interactions

	Reactome
			EGR2 and SOX10-mediated initiation of Schwann cell myelination

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID	References
Causal
Rheumatoid arthritis	Rheumatoid Arthritis	rs587776843	21673997
Schizophrenia	Schizophrenia	rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346 View all (12 more)	24788877, 22675524, 19154657, 16213148

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Periodontal Diseases	Periodontal Diseases			GWAS

Show/Hide Text Mining Associations (98)

Disease Name	Relationship Type	References
Associations from Text Mining
Acquired Immunodeficiency Syndrome	Associate	15996199
Allergic Fungal Sinusitis	Associate	25361058
Alzheimer Disease	Associate	19385666, 24586351
Amyotrophic Lateral Sclerosis	Associate	29337119
Aortic Aneurysm Thoracic	Associate	34469433
Arginine Glycine Amidinotransferase Deficiency	Associate	19575800
Arthritis Rheumatoid	Associate	21673997
Autism Spectrum Disorder	Associate	34948243
Autoimmune Diseases	Associate	10716924, 37506490, 7679118, 8967755
Behcet Syndrome	Stimulate	27701407
Bipolar Disorder	Associate	25539505
Blister	Associate	9602632
Brain Infarction	Associate	36529041
Carcinoma Hepatocellular	Associate	9223425
CD59 Deficiency	Associate	15634673
Central Nervous System Infections	Associate	37876925
Cerebral Amyloid Angiopathy	Associate	19385666
Chromosome 18 deletion syndrome	Associate	8728701, 8933867
Cognition Disorders	Associate	27235342
Colorectal Neoplasms	Inhibit	15634673
Congenital Abnormalities	Associate	36613580
Conjunctivitis	Associate	9602632
Cystic Fibrosis	Associate	7545672
Demyelinating Diseases	Associate	10961633, 19726693, 24662633, 24907905, 9077532
Demyelinating Diseases	Inhibit	19559391
Demyelinating Diseases	Stimulate	29877287
Depressive Disorder Major	Associate	34706460
Dermatitis Atopic	Associate	34293355
Drug Hypersensitivity	Stimulate	24814827
Encephalitis Viral	Associate	15996199
Encephalomyelitis Autoimmune Experimental	Stimulate	7515505
Encephalomyelitis Autoimmune Experimental	Associate	7692995
Eosinophilia Familial	Stimulate	14988154
Epilepsy Partial with Variable Foci	Associate	27874947
Epstein Barr Virus Infections	Associate	22201827
Esophageal Squamous Cell Carcinoma	Associate	18978176
Fetal Alcohol Spectrum Disorders	Associate	36613580
Geographic Atrophy	Associate	24667176
Growth Disorders	Associate	8536386
Hashimoto Disease	Associate	3499269
Heredodegenerative Disorders Nervous System	Associate	7542576
HIV Infections	Associate	26033855, 33435385
Hodgkin Disease	Associate	3535925
Hypersensitivity Immediate	Stimulate	36529041
Immunoglobulin G4 Related Disease	Associate	36609529
Infections	Associate	37876925
Inflammation	Associate	11602626, 19726693, 19822525, 21673997, 7531438, 7692995
Inflammation	Stimulate	22524708
Ischemia	Stimulate	36529041
Ischemia	Associate	36529041
Leukemia	Associate	20438785
Leukoencephalopathies	Associate	29596541, 33189883, 37286732, 8933867
Lichen Sclerosus et Atrophicus	Associate	20606538
Lymphoma Follicular	Inhibit	23055202
Lymphoma Follicular	Associate	23055202
Lymphoma Large B Cell Diffuse	Associate	23055202
Lymphoma Non Hodgkin	Inhibit	23055202
Lymphoma Non Hodgkin	Associate	23055202
Macular Degeneration	Associate	24667176
Malaria Cerebral	Associate	33942992
Mannose Binding Protein Deficiency	Associate	15634673
Mental Disorders	Associate	31291231
Movement Disorders	Associate	30214633
Multiple Endocrine Neoplasia Type 2a	Associate	2477486
Multiple Sclerosis	Associate	10320650, 10716924, 11319230, 14991617, 15572592, 15996199, 16295528, 16547138, 1702137, 1706524, 1717998, 17448727, 18616943, 19531498, 19726693 View all (41 more)
Nasal Polyps	Stimulate	25361058
Neoplasms	Associate	15446585, 24236209, 29606096, 9223425
Neuralgia	Associate	38521157
Obesity	Associate	26073637
Obesity Abdominal	Associate	26073637
Oligodendroglioma	Associate	24236209
Otitis Media with Effusion	Associate	8403525
Pallor	Associate	15996199
Panic Disorder	Associate	26283638
Pediatric Obesity	Associate	8536386
Pemphigoid Benign Mucous Membrane	Associate	9602632
Pemphigoid Bullous	Stimulate	28684769
Pemphigoid Bullous	Associate	9602632
Plaque Amyloid	Associate	16906282, 19385666
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	20438785, 29125853
Psychotic Disorders	Associate	27701407
Restless Legs Syndrome	Associate	21570342
Retinoblastoma	Associate	3013012
Rhinitis	Associate	10543283
Ring Chromosome 20 Syndrome	Stimulate	36529041
Schizophrenia	Inhibit	22675524
Schizophrenia	Associate	25539505
Schizophrenia	Stimulate	27701407
Schizophrenia Spectrum and Other Psychotic Disorders	Stimulate	34706460
Sclerosis	Associate	3535925
Seizures	Associate	10961633
Skin Diseases	Associate	30779748
Sleep Apnea Obstructive	Associate	34146730
Status Asthmaticus	Associate	25361058, 31058187
Stress Disorders Post Traumatic	Associate	31291231
Stroke	Associate	22287710, 27235342
Trauma Nervous System	Associate	22897631
X Linked Combined Immunodeficiency Diseases	Associate	32431704

MBP (myelin basic protein)