MBP (myelin basic protein)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 4155 |
| Gene name | Myelin basic protein |
| Gene symbol | MBP |
| Synonyms (NCBI Gene) |
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| Chromosome | 18 |
| Chromosome location | 18q23 |
| Summary | The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs ar |
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miRNA
miRNA information provided by mirtarbase database.
310
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Transcription factors
Transcription factors information provided by TRRUST V2 database.
3
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
41
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P02686 | ||||||||||
| Protein name | Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein) | ||||||||||
| Protein function | The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important | ||||||||||
| PDB | 1BX2 , 1FV1 , 1HQR , 1K2D , 1YMM , 1ZGL | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: MBP isoforms are found in both the central and the peripheral nervous system, whereas Golli-MBP isoforms are expressed in fetal thymus, spleen and spinal cord, as well as in cell lines derived from the immune system. {ECO:0000269|PubMe | ||||||||||
| Sequence |
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| Sequence length | 304 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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