Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Diabetes mellitus |
Diabetes Mellitus, Non-Insulin-Dependent |
rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs1362648752, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237, rs80356613, rs387906407, rs151344623, rs28938469, rs28936371, rs137852672, rs80356637, rs80356642, rs80356653, rs137852673, rs137852674, rs80356634, rs80356651, rs193929360, rs137853334, rs137853335, rs137853336, rs1600731198, rs137853338, rs121964882, rs121964883, rs387906511, rs121964884, rs121964885, rs2147483647, rs387906512, rs121964887, rs121964888, rs121964889, rs121964890, rs121964891, rs28934878, rs74315383, rs121964893, rs886037620, rs886037621, rs121434593, rs121913150, rs587776825, rs137853236, rs2135842335, rs137853237, rs137853238, rs2135818776, rs1566092470, rs1463923467, rs137853243, rs137853244, rs2135839114, rs137853245, rs2135847417, rs121918407, rs104894005, rs104894006, rs80356655, rs104894008, rs104894009, rs104894010, rs104894011, rs80356654, rs104894016, rs193929376, rs193929374, rs193929375, rs193929373, rs80356669, rs80356664, rs193929366, rs1048095, rs193929355, rs193929356, rs1259467443, rs104893642, rs387906777, rs193922396, rs193922400, rs193922401, rs137852676, rs193922407, rs193922638, rs193922257, rs193922258, rs193922259, rs193922260, rs193922261, rs193922262, rs193922263, rs193922264, rs193922265, rs193922268, rs193921338, rs193922269, rs193922272, rs193922273, rs193922275, rs193922278, rs193922279, rs193922280, rs193922281, rs193922282, rs193922283, rs193922284, rs193922286, rs193922287, rs193922289, rs193922291, rs193922295, rs193922297, rs193922300, rs193922302, rs193922303, rs193922308, rs193922313, rs193922314, rs144723656, rs193922315, rs193922316, rs193922317, rs148311934, rs193922319, rs193922320, rs193922326, rs193922329, rs193922330, rs193922331, rs193922335, rs193922336, rs193922338, rs193922340, rs193922341, rs193922471, rs193922475, rs193922476, rs193922479, rs80356663, rs193922355, rs193922356, rs193922576, rs193922578, rs193922582, rs193922588, rs193922592, rs193922594, rs193922596, rs386134267, rs193922598, rs193922599, rs193922600, rs193922604, rs193922605, rs397514580, rs397515519, rs267601516, rs587780343, rs587780345, rs587780346, rs587780347, rs587780357, rs148954387, rs587783672, rs587783669, rs786204676, rs794727236, rs151344624, rs794727775, rs794727839, rs199946797, rs869320673, rs796065047, rs759072800, rs797045595, rs797045209, rs797045207, rs797045213, rs863225280, rs149703259, rs864321656, rs139964066, rs777870079, rs878853246, rs769268803, rs886039380, rs886041392, rs886041391, rs886042610, rs143064649, rs1057516192, rs746480424, rs1057516281, rs576684889, rs754728827, rs1057520291, rs1057520779, rs893256143, rs1057520504, rs1057524790, rs1057524902, rs1057524904, rs1057524905, rs764232985, rs1064793998, rs1064794268, rs769086289, rs369429452, rs1085307913, rs1131691416, rs765432081, rs1131692182, rs748749585, rs1554335441, rs762263694, rs1312678560, rs767565869, rs1375656631, rs1554335391, rs1360415315, rs1554335616, rs1554335752, rs1554909277, rs769518471, rs757171524, rs768951263, rs762703502, rs1555212248, rs1555212359, rs1555813319, rs1555816654, rs371977235, rs1415041911, rs1554334894, rs1260178539, rs1554335421, rs1555211904, rs779184183, rs1554335564, rs200670692, rs1400535021, rs1554334872, rs1555212749, rs1553876668, rs1553878211, rs954727530, rs1554924035, rs372307320, rs925231098, rs1554913069, rs1554933565, rs766431403, rs746714109, rs751279984, rs770664202, rs1008906426, rs758844607, rs1554924540, rs1566092307, rs753998395, rs1565885935, rs1167124132, rs1376796469, rs556436603, rs1562715657, rs1486280029, rs1564869850, rs755259997, rs769569410, rs1172328722, rs1286294151, rs1375557127, rs1568731279, rs1562715426, rs556581174, rs1564865302, rs1565886545, rs1568724014, rs1392795567, rs781260712, rs1562719705, rs1382448285, rs1564977373, rs750586210, rs1598842892, rs1583592247, rs780612692, rs1593060859, rs1476637197, rs751279776, rs1593060890, rs1191912908, rs1167675604, rs1583601110, rs1593058932, rs778611627, rs753296261 View all (293 more) |
30054458 |
Prostate cancer |
Prostate carcinoma, Prostate cancer, familial |
rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 |
29892016 |
Prostate cancer, hereditary |
PROSTATE CANCER, HEREDITARY, 1 |
rs387906327, rs193929331, rs74315365, rs397516896, rs794729219, rs121913349, rs587782641, rs1114167673, rs1597371666, rs2073394466 |
29892016 |
Schizophrenia |
Schizophrenia |
rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 View all (12 more) |
17464717 |
|
Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Myotonic dystrophy |
MYOTONIC DYSTROPHY 1 |
|
27222292, 11929853 |
ClinVar |
Diabetes |
Diabetes |
|
|
GWAS |
Metabolic Syndrome |
Metabolic Syndrome |
|
|
GWAS |
Neuroticism |
Neuroticism |
|
|
GWAS |
Colorectal Cancer |
Colorectal Cancer |
In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1. |
|
GWAS, CBGDA |
Sarcoidosis |
Sarcoidosis |
|
|
GWAS |
|
Associations from Text Mining |
Disease Name |
Relationship Type |
References |
Atherosclerosis |
Associate
|
29771377, 33759281 |
Autoimmune Diseases |
Associate
|
29771377 |
Bethlem myopathy |
Associate
|
36862922 |
Breast Neoplasms |
Associate
|
25913416, 35421923 |
Breast Neoplasms |
Inhibit
|
32601196, 35094653, 35112997 |
Carcinogenesis |
Associate
|
35421923, 36908851 |
Carcinoma Non Small Cell Lung |
Associate
|
31113460 |
Carcinoma Renal Cell |
Associate
|
40171812 |
Carcinoma Small Cell |
Associate
|
35421923 |
Carcinoma Squamous Cell |
Inhibit
|
33896245 |
Cardiovascular Diseases |
Associate
|
36785792 |
Cell Transformation Neoplastic |
Inhibit
|
32601196 |
Colorectal Neoplasms |
Inhibit
|
30664186, 37711058 |
Colorectal Neoplasms |
Associate
|
32221048, 33142236, 33893082 |
Coronary Artery Disease |
Associate
|
31861407 |
Endometrial Neoplasms |
Associate
|
36232772 |
Endometriosis |
Associate
|
38115253 |
Epilepsy rolandic with paroxysmal exercise induced dystonia and writer's cramp |
Associate
|
31469403 |
Esophageal Neoplasms |
Associate
|
36204878 |
Fasciculation |
Associate
|
31116797 |
Fibrosis |
Associate
|
36142381 |
Fuchs' Endothelial Dystrophy |
Associate
|
28118661, 28886202, 31469403 |
Heredodegenerative Disorders Nervous System |
Associate
|
22252896 |
Huntington Disease |
Associate
|
21247881, 24377303 |
Hypoxia |
Associate
|
36785792 |
Idiopathic Pulmonary Fibrosis |
Associate
|
38035073 |
Inflammation |
Associate
|
36142381 |
Leukemia Myeloid Acute |
Associate
|
22581002 |
Muscular Dystrophy Duchenne |
Associate
|
36619896 |
Myocardial Infarction |
Associate
|
36785792 |
Myotonia |
Associate
|
28535287 |
Myotonic Dystrophy |
Associate
|
11433021, 15546872, 16487687, 16920640, 16946708, 17306536, 17846170, 17942744, 19095965, 19864209, 20071745, 21454535, 21768123, 21794030, 22218462, 22300544, 23166594, 23423380, 23480597, 23949219, 24376746, 24377303, 24440524, 24781112, 24938413, 25593321, 25702800, 27010216, 27222292, 28535287, 28886202, 29334465, 29771377, 29947794, 30730308, 31116797, 31981476, 32407311, 32683410, 33530452, 34312665, 34520479, 35213019, 36222125, 36555788, 36631509, 39326259, 39383229 View all (33 more) |
Neoplasm Metastasis |
Inhibit
|
30664186, 32601196, 33896245, 36908851, 40171812 |
Neoplasm Metastasis |
Associate
|
32576660, 36204878 |
Neoplasms |
Associate
|
25908786, 27197215, 28489605, 29592900, 29771377, 36217202 |
Neoplasms |
Inhibit
|
32601196, 33893082, 33896245, 35094653, 35112997, 36908851, 37711058 |
Oculopharyngodistal Myopathy |
Associate
|
33693509 |
Pancreatic Neoplasms |
Inhibit
|
36908851 |
Prostatic Neoplasms |
Associate
|
33648424 |
Pyloric Stenosis Hypertrophic |
Associate
|
22306654 |
Sezary Syndrome |
Associate
|
28489605 |
Squamous Cell Carcinoma of Head and Neck |
Associate
|
34805417 |
Stomach Neoplasms |
Associate
|
35421923 |
Tissue Adhesions |
Associate
|
34968168 |
Triple Negative Breast Neoplasms |
Inhibit
|
32601196 |
Urinary Bladder Neoplasms |
Associate
|
31769229 |
|