PIM3 (Pim-3 proto-oncogene, serine/threonine kinase)
|
Gene
Gene information from NCBI Gene database.
|
|
| Entrez ID | 415116 |
| Gene name | Pim-3 proto-oncogene, serine/threonine kinase |
| Gene symbol | PIM3 |
| Synonyms (NCBI Gene) |
pim-3
|
| Chromosome | 22 |
| Chromosome location | 22q13.33 |
| Summary | The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transd |
|
miRNA
miRNA information provided by mirtarbase database.
389
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
23
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
|
|||||||
|
|||||||
|
Protein
Protein information from UniProt database.
|
|||||||||||
|
UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
|
Q86V86 | ||||||||||
| Protein name | Serine/threonine-protein kinase pim-3 (EC 2.7.11.1) | ||||||||||
| Protein function | Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which indu | ||||||||||
| Family and domains |
Pfam
|
||||||||||
| Tissue specificity | TISSUE SPECIFICITY: Detected in various tissues, including the heart, brain, lung, kidney, spleen, placenta, skeletal muscle, and peripheral blood leukocytes. Not found or barely expressed in the normal adult endoderm-derived organs such as colon, thymus, | ||||||||||
| Sequence |
|
||||||||||
| Sequence length | 326 | ||||||||||
| Interactions | View interactions | ||||||||||