Gene Gene information from NCBI Gene database.
Entrez ID 415116
Gene name Pim-3 proto-oncogene, serine/threonine kinase
Gene symbol PIM3
Synonyms (NCBI Gene)
pim-3
Chromosome 22
Chromosome location 22q13.33
Summary The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transd
miRNA miRNA information provided by mirtarbase database.
389
miRTarBase ID miRNA Experiments Reference
MIRT019570 hsa-miR-340-5p Sequencing 20371350
MIRT028210 hsa-miR-33a-5p Sequencing 20371350
MIRT043598 hsa-miR-151a-3p CLASH 23622248
MIRT039901 hsa-miR-615-3p CLASH 23622248
MIRT037665 hsa-miR-744-5p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
23
GO ID Ontology Definition Evidence Reference
GO:0000166 Function Nucleotide binding IEA
GO:0004672 Function Protein kinase activity IEA
GO:0004674 Function Protein serine/threonine kinase activity IBA
GO:0004674 Function Protein serine/threonine kinase activity IDA 18593906
GO:0004674 Function Protein serine/threonine kinase activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
610580 19310 ENSG00000198355
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q86V86
Protein name Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)
Protein function Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which indu
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00069 Pkinase 40 293 Protein kinase domain Domain
Tissue specificity TISSUE SPECIFICITY: Detected in various tissues, including the heart, brain, lung, kidney, spleen, placenta, skeletal muscle, and peripheral blood leukocytes. Not found or barely expressed in the normal adult endoderm-derived organs such as colon, thymus,
Sequence
Sequence length 326
Interactions View interactions