Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	415116
Gene name Gene Name - the full gene name approved by the HGNC.	Pim-3 proto-oncogene, serine/threonine kinase
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PIM3
Synonyms (NCBI Gene) Gene synonyms aliases	pim-3
Chromosome Chromosome number	22
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	22q13.33
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transd

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miRTarBase ID	miRNA	Experiments	Reference
MIRT019570	hsa-miR-340-5p	Sequencing	20371350
MIRT028210	hsa-miR-33a-5p	Sequencing	20371350
MIRT043598	hsa-miR-151a-3p	CLASH	23622248
MIRT039901	hsa-miR-615-3p	CLASH	23622248
MIRT037665	hsa-miR-744-5p	CLASH	23622248
MIRT036626	hsa-miR-940	CLASH	23622248
MIRT566421	hsa-miR-203a-3p	PAR-CLIP	20371350
MIRT088271	hsa-miR-4517	PAR-CLIP	20371350
MIRT566420	hsa-miR-3163	PAR-CLIP	20371350
MIRT566419	hsa-miR-766-3p	PAR-CLIP	20371350
MIRT566418	hsa-miR-3925-3p	PAR-CLIP	20371350
MIRT566417	hsa-miR-4695-3p	PAR-CLIP	20371350
MIRT088272	hsa-miR-7641	PAR-CLIP	20371350
MIRT088270	hsa-miR-568	PAR-CLIP	20371350
MIRT471055	hsa-miR-3150a-5p	PAR-CLIP	23592263
MIRT471054	hsa-miR-3150b-5p	PAR-CLIP	23592263
MIRT353104	hsa-miR-3125	PAR-CLIP	23592263
MIRT353106	hsa-miR-3916	PAR-CLIP	23592263
MIRT353115	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT353103	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT353111	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT353107	hsa-miR-4494	PAR-CLIP	23592263
MIRT353114	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT471053	hsa-miR-4257	PAR-CLIP	23592263
MIRT353101	hsa-miR-767-3p	PAR-CLIP	23592263
MIRT353102	hsa-miR-1827	PAR-CLIP	23592263
MIRT353109	hsa-miR-4771	PAR-CLIP	23592263
MIRT254870	hsa-miR-3934-3p	PAR-CLIP	23592263
MIRT471052	hsa-miR-6878-5p	PAR-CLIP	23592263
MIRT353112	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT353116	hsa-miR-8085	PAR-CLIP	23592263
MIRT471051	hsa-miR-4489	PAR-CLIP	23592263
MIRT471050	hsa-miR-4283	PAR-CLIP	23592263
MIRT471049	hsa-miR-185-3p	PAR-CLIP	23592263
MIRT353100	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT353099	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT353113	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT471048	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT471047	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT471046	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT471045	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT471044	hsa-miR-3689c	PAR-CLIP	23592263
MIRT471043	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT471042	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT471041	hsa-miR-887-5p	PAR-CLIP	23592263
MIRT028210	hsa-miR-33a-5p	Immunoprecipitaion, Luciferase reporter assay, qRT-PCR, Western blot	25971209
MIRT471048	hsa-miR-1273h-5p	PAR-CLIP	26701625
MIRT353102	hsa-miR-1827	PAR-CLIP	26701625
MIRT353103	hsa-miR-1910-3p	PAR-CLIP	26701625
MIRT471047	hsa-miR-30b-3p	PAR-CLIP	26701625
MIRT353100	hsa-miR-30c-1-3p	PAR-CLIP	26701625
MIRT353099	hsa-miR-30c-2-3p	PAR-CLIP	26701625
MIRT353104	hsa-miR-3125	PAR-CLIP	26701625
MIRT471055	hsa-miR-3150a-5p	PAR-CLIP	26701625
MIRT471054	hsa-miR-3150b-5p	PAR-CLIP	26701625
MIRT471046	hsa-miR-3689a-3p	PAR-CLIP	26701625
MIRT471045	hsa-miR-3689b-3p	PAR-CLIP	26701625
MIRT471044	hsa-miR-3689c	PAR-CLIP	26701625
MIRT353106	hsa-miR-3916	PAR-CLIP	26701625
MIRT254870	hsa-miR-3934-3p	PAR-CLIP	26701625
MIRT471053	hsa-miR-4257	PAR-CLIP	26701625
MIRT353107	hsa-miR-4494	PAR-CLIP	26701625
MIRT353109	hsa-miR-4771	PAR-CLIP	26701625
MIRT353111	hsa-miR-6511a-5p	PAR-CLIP	26701625
MIRT353112	hsa-miR-6731-5p	PAR-CLIP	26701625
MIRT471043	hsa-miR-6779-5p	PAR-CLIP	26701625
MIRT471042	hsa-miR-6780a-5p	PAR-CLIP	26701625
MIRT353113	hsa-miR-6788-5p	PAR-CLIP	26701625
MIRT353114	hsa-miR-6847-5p	PAR-CLIP	26701625
MIRT353115	hsa-miR-6859-5p	PAR-CLIP	26701625
MIRT471052	hsa-miR-6878-5p	PAR-CLIP	26701625
MIRT353101	hsa-miR-767-3p	PAR-CLIP	26701625
MIRT353116	hsa-miR-8085	PAR-CLIP	26701625
MIRT471041	hsa-miR-887-5p	PAR-CLIP	26701625
MIRT566421	hsa-miR-203a-3p	PAR-CLIP	20371350
MIRT088271	hsa-miR-4517	PAR-CLIP	20371350
MIRT566420	hsa-miR-3163	PAR-CLIP	20371350
MIRT566419	hsa-miR-766-3p	PAR-CLIP	20371350
MIRT566418	hsa-miR-3925-3p	PAR-CLIP	20371350
MIRT566417	hsa-miR-4695-3p	PAR-CLIP	20371350
MIRT088272	hsa-miR-7641	PAR-CLIP	20371350
MIRT088270	hsa-miR-568	PAR-CLIP	20371350
MIRT471055	hsa-miR-3150a-5p	PAR-CLIP	23592263
MIRT471054	hsa-miR-3150b-5p	PAR-CLIP	23592263
MIRT353104	hsa-miR-3125	PAR-CLIP	23592263
MIRT353106	hsa-miR-3916	PAR-CLIP	23592263
MIRT353115	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT353103	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT353111	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT353107	hsa-miR-4494	PAR-CLIP	23592263
MIRT353114	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT471053	hsa-miR-4257	PAR-CLIP	23592263
MIRT353101	hsa-miR-767-3p	PAR-CLIP	23592263
MIRT353102	hsa-miR-1827	PAR-CLIP	23592263
MIRT353109	hsa-miR-4771	PAR-CLIP	23592263
MIRT254870	hsa-miR-3934-3p	PAR-CLIP	23592263
MIRT471052	hsa-miR-6878-5p	PAR-CLIP	23592263
MIRT353112	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT353116	hsa-miR-8085	PAR-CLIP	23592263
MIRT471051	hsa-miR-4489	PAR-CLIP	23592263
MIRT471050	hsa-miR-4283	PAR-CLIP	23592263
MIRT471049	hsa-miR-185-3p	PAR-CLIP	23592263
MIRT353100	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT353099	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT353113	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT471048	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT471047	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT471046	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT471045	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT471044	hsa-miR-3689c	PAR-CLIP	23592263
MIRT471043	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT471042	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT471041	hsa-miR-887-5p	PAR-CLIP	23592263
MIRT1235212	hsa-miR-1206	CLIP-seq
MIRT1235213	hsa-miR-1226	CLIP-seq
MIRT1235214	hsa-miR-1254	CLIP-seq
MIRT1235215	hsa-miR-125a-3p	CLIP-seq
MIRT1235216	hsa-miR-1276	CLIP-seq
MIRT1235217	hsa-miR-128	CLIP-seq
MIRT1235218	hsa-miR-1281	CLIP-seq
MIRT1235219	hsa-miR-1284	CLIP-seq
MIRT1235220	hsa-miR-1285	CLIP-seq
MIRT1235221	hsa-miR-1286	CLIP-seq
MIRT1235222	hsa-miR-1297	CLIP-seq
MIRT1235223	hsa-miR-1301	CLIP-seq
MIRT1235224	hsa-miR-1302	CLIP-seq
MIRT1235225	hsa-miR-147	CLIP-seq
MIRT1235226	hsa-miR-1471	CLIP-seq
MIRT1235227	hsa-miR-1539	CLIP-seq
MIRT1235228	hsa-miR-15a	CLIP-seq
MIRT1235229	hsa-miR-15b	CLIP-seq
MIRT1235230	hsa-miR-16	CLIP-seq
MIRT1235231	hsa-miR-1915	CLIP-seq
MIRT1235232	hsa-miR-195	CLIP-seq
MIRT1235233	hsa-miR-2115	CLIP-seq
MIRT1235234	hsa-miR-26a	CLIP-seq
MIRT1235235	hsa-miR-26b	CLIP-seq
MIRT1235236	hsa-miR-3116	CLIP-seq
MIRT1235237	hsa-miR-3122	CLIP-seq
MIRT1235238	hsa-miR-3141	CLIP-seq
MIRT1235239	hsa-miR-3150b-3p	CLIP-seq
MIRT1235240	hsa-miR-3169	CLIP-seq
MIRT1235241	hsa-miR-3170	CLIP-seq
MIRT1235242	hsa-miR-3176	CLIP-seq
MIRT1235243	hsa-miR-3178	CLIP-seq
MIRT1235244	hsa-miR-3182	CLIP-seq
MIRT1235245	hsa-miR-3184	CLIP-seq
MIRT1235246	hsa-miR-3187-5p	CLIP-seq
MIRT1235247	hsa-miR-3195	CLIP-seq
MIRT1235248	hsa-miR-323-5p	CLIP-seq
MIRT1235249	hsa-miR-329	CLIP-seq
MIRT1235250	hsa-miR-331-3p	CLIP-seq
MIRT1235251	hsa-miR-33a	CLIP-seq
MIRT1235252	hsa-miR-33b	CLIP-seq
MIRT1235253	hsa-miR-3545-3p	CLIP-seq
MIRT1235254	hsa-miR-3616-3p	CLIP-seq
MIRT1235255	hsa-miR-362-3p	CLIP-seq
MIRT1235256	hsa-miR-3649	CLIP-seq
MIRT1235257	hsa-miR-3660	CLIP-seq
MIRT1235258	hsa-miR-3665	CLIP-seq
MIRT1235259	hsa-miR-3687	CLIP-seq
MIRT1235260	hsa-miR-3689d	CLIP-seq
MIRT1235261	hsa-miR-3691-3p	CLIP-seq
MIRT1235262	hsa-miR-3714	CLIP-seq
MIRT1235263	hsa-miR-377	CLIP-seq
MIRT1235264	hsa-miR-3913-5p	CLIP-seq
MIRT1235265	hsa-miR-3922-3p	CLIP-seq
MIRT1235266	hsa-miR-3926	CLIP-seq
MIRT1235267	hsa-miR-3934	CLIP-seq
MIRT1235268	hsa-miR-3944-5p	CLIP-seq
MIRT1235269	hsa-miR-423-5p	CLIP-seq
MIRT1235270	hsa-miR-424	CLIP-seq
MIRT1235271	hsa-miR-4256	CLIP-seq
MIRT1235272	hsa-miR-4281	CLIP-seq
MIRT1235273	hsa-miR-4286	CLIP-seq
MIRT1235274	hsa-miR-4289	CLIP-seq
MIRT1235275	hsa-miR-4292	CLIP-seq
MIRT1235276	hsa-miR-4298	CLIP-seq
MIRT1235277	hsa-miR-4417	CLIP-seq
MIRT1235278	hsa-miR-4442	CLIP-seq
MIRT1235279	hsa-miR-4459	CLIP-seq
MIRT1235280	hsa-miR-4465	CLIP-seq
MIRT1235281	hsa-miR-4493	CLIP-seq
MIRT1235282	hsa-miR-4514	CLIP-seq
MIRT1235283	hsa-miR-4526	CLIP-seq
MIRT1235284	hsa-miR-4660	CLIP-seq
MIRT1235285	hsa-miR-4662a-5p	CLIP-seq
MIRT1235286	hsa-miR-4666-5p	CLIP-seq
MIRT1235287	hsa-miR-4667-5p	CLIP-seq
MIRT1235288	hsa-miR-4685-5p	CLIP-seq
MIRT1235289	hsa-miR-4692	CLIP-seq
MIRT1235290	hsa-miR-4700-5p	CLIP-seq
MIRT1235291	hsa-miR-4721	CLIP-seq
MIRT1235292	hsa-miR-4722-5p	CLIP-seq
MIRT1235293	hsa-miR-4725-5p	CLIP-seq
MIRT1235294	hsa-miR-4726-3p	CLIP-seq
MIRT1235295	hsa-miR-4733-3p	CLIP-seq
MIRT1235296	hsa-miR-4736	CLIP-seq
MIRT1235297	hsa-miR-4740-5p	CLIP-seq
MIRT1235298	hsa-miR-4747-5p	CLIP-seq
MIRT1235299	hsa-miR-4763-5p	CLIP-seq
MIRT1235300	hsa-miR-4766-5p	CLIP-seq
MIRT1235301	hsa-miR-4767	CLIP-seq
MIRT1235302	hsa-miR-4784	CLIP-seq
MIRT1235303	hsa-miR-497	CLIP-seq
MIRT1235304	hsa-miR-504	CLIP-seq
MIRT1235305	hsa-miR-5047	CLIP-seq
MIRT1235306	hsa-miR-515-3p	CLIP-seq
MIRT1235307	hsa-miR-516a-3p	CLIP-seq
MIRT1235308	hsa-miR-519e	CLIP-seq
MIRT1235309	hsa-miR-520d-5p	CLIP-seq
MIRT1235310	hsa-miR-524-5p	CLIP-seq
MIRT1235311	hsa-miR-539	CLIP-seq
MIRT1235312	hsa-miR-541	CLIP-seq
MIRT1235313	hsa-miR-548aa	CLIP-seq
MIRT1235314	hsa-miR-548s	CLIP-seq
MIRT1235315	hsa-miR-550a	CLIP-seq
MIRT1235316	hsa-miR-580	CLIP-seq
MIRT1235317	hsa-miR-612	CLIP-seq
MIRT1235318	hsa-miR-637	CLIP-seq
MIRT1235319	hsa-miR-654-5p	CLIP-seq
MIRT1235320	hsa-miR-658	CLIP-seq
MIRT1235321	hsa-miR-661	CLIP-seq
MIRT1235322	hsa-miR-764	CLIP-seq
MIRT1235323	hsa-miR-765	CLIP-seq
MIRT1235324	hsa-miR-766	CLIP-seq
MIRT1235254	hsa-miR-3616-3p	CLIP-seq
MIRT1235312	hsa-miR-541	CLIP-seq
MIRT1235319	hsa-miR-654-5p	CLIP-seq
MIRT1235254	hsa-miR-3616-3p	CLIP-seq
MIRT1235291	hsa-miR-4721	CLIP-seq
MIRT2069248	hsa-miR-1182	CLIP-seq
MIRT2069249	hsa-miR-1228	CLIP-seq
MIRT1235215	hsa-miR-125a-3p	CLIP-seq
MIRT1235222	hsa-miR-1297	CLIP-seq
MIRT1235223	hsa-miR-1301	CLIP-seq
MIRT1235228	hsa-miR-15a	CLIP-seq
MIRT1235229	hsa-miR-15b	CLIP-seq
MIRT1235230	hsa-miR-16	CLIP-seq
MIRT2069250	hsa-miR-1908	CLIP-seq
MIRT1235231	hsa-miR-1915	CLIP-seq
MIRT1235232	hsa-miR-195	CLIP-seq
MIRT1235233	hsa-miR-2115	CLIP-seq
MIRT1235234	hsa-miR-26a	CLIP-seq
MIRT1235235	hsa-miR-26b	CLIP-seq
MIRT2069251	hsa-miR-3133	CLIP-seq
MIRT1235239	hsa-miR-3150b-3p	CLIP-seq
MIRT2069252	hsa-miR-3155	CLIP-seq
MIRT2069253	hsa-miR-3155b	CLIP-seq
MIRT1235241	hsa-miR-3170	CLIP-seq
MIRT1235242	hsa-miR-3176	CLIP-seq
MIRT1235245	hsa-miR-3184	CLIP-seq
MIRT1235253	hsa-miR-3545-3p	CLIP-seq
MIRT1235263	hsa-miR-377	CLIP-seq
MIRT1235265	hsa-miR-3922-3p	CLIP-seq
MIRT1235267	hsa-miR-3934	CLIP-seq
MIRT2069254	hsa-miR-3937	CLIP-seq
MIRT2069255	hsa-miR-3942-3p	CLIP-seq
MIRT1235268	hsa-miR-3944-5p	CLIP-seq
MIRT1235269	hsa-miR-423-5p	CLIP-seq
MIRT1235270	hsa-miR-424	CLIP-seq
MIRT2069256	hsa-miR-4269	CLIP-seq
MIRT1235279	hsa-miR-4459	CLIP-seq
MIRT1235280	hsa-miR-4465	CLIP-seq
MIRT2069257	hsa-miR-4467	CLIP-seq
MIRT2069258	hsa-miR-4488	CLIP-seq
MIRT2069259	hsa-miR-4645-5p	CLIP-seq
MIRT1235284	hsa-miR-4660	CLIP-seq
MIRT1235287	hsa-miR-4667-5p	CLIP-seq
MIRT2069260	hsa-miR-4673	CLIP-seq
MIRT1235288	hsa-miR-4685-5p	CLIP-seq
MIRT2069261	hsa-miR-4697-5p	CLIP-seq
MIRT1235290	hsa-miR-4700-5p	CLIP-seq
MIRT2069262	hsa-miR-4715-5p	CLIP-seq
MIRT1235292	hsa-miR-4722-5p	CLIP-seq
MIRT2069263	hsa-miR-4724-5p	CLIP-seq
MIRT1235294	hsa-miR-4726-3p	CLIP-seq
MIRT2069264	hsa-miR-4730	CLIP-seq
MIRT2069265	hsa-miR-4755-3p	CLIP-seq
MIRT2069266	hsa-miR-4758-3p	CLIP-seq
MIRT1235300	hsa-miR-4766-5p	CLIP-seq
MIRT2069267	hsa-miR-4768-3p	CLIP-seq
MIRT1235302	hsa-miR-4784	CLIP-seq
MIRT2069268	hsa-miR-4797-5p	CLIP-seq
MIRT2069269	hsa-miR-484	CLIP-seq
MIRT1235303	hsa-miR-497	CLIP-seq
MIRT1235305	hsa-miR-5047	CLIP-seq
MIRT1235307	hsa-miR-516a-3p	CLIP-seq
MIRT2069270	hsa-miR-548b-3p	CLIP-seq
MIRT2069271	hsa-miR-571	CLIP-seq
MIRT2069272	hsa-miR-574-3p	CLIP-seq
MIRT1235318	hsa-miR-637	CLIP-seq
MIRT2069273	hsa-miR-663	CLIP-seq
MIRT2069274	hsa-miR-744	CLIP-seq
MIRT2069275	hsa-miR-760	CLIP-seq
MIRT1235322	hsa-miR-764	CLIP-seq
MIRT1235323	hsa-miR-765	CLIP-seq
MIRT1235324	hsa-miR-766	CLIP-seq
MIRT2069248	hsa-miR-1182	CLIP-seq
MIRT1235212	hsa-miR-1206	CLIP-seq
MIRT2069249	hsa-miR-1228	CLIP-seq
MIRT2296328	hsa-miR-124	CLIP-seq
MIRT1235215	hsa-miR-125a-3p	CLIP-seq
MIRT1235218	hsa-miR-1281	CLIP-seq
MIRT1235219	hsa-miR-1284	CLIP-seq
MIRT1235222	hsa-miR-1297	CLIP-seq
MIRT2296329	hsa-miR-140-3p	CLIP-seq
MIRT1235226	hsa-miR-1471	CLIP-seq
MIRT1235228	hsa-miR-15a	CLIP-seq
MIRT1235229	hsa-miR-15b	CLIP-seq
MIRT1235230	hsa-miR-16	CLIP-seq
MIRT1235231	hsa-miR-1915	CLIP-seq
MIRT1235232	hsa-miR-195	CLIP-seq
MIRT1235233	hsa-miR-2115	CLIP-seq
MIRT1235234	hsa-miR-26a	CLIP-seq
MIRT1235235	hsa-miR-26b	CLIP-seq
MIRT2069251	hsa-miR-3133	CLIP-seq
MIRT1235239	hsa-miR-3150b-3p	CLIP-seq
MIRT1235241	hsa-miR-3170	CLIP-seq
MIRT1235242	hsa-miR-3176	CLIP-seq
MIRT1235245	hsa-miR-3184	CLIP-seq
MIRT1235248	hsa-miR-323-5p	CLIP-seq
MIRT1235249	hsa-miR-329	CLIP-seq
MIRT2296330	hsa-miR-330-3p	CLIP-seq
MIRT1235250	hsa-miR-331-3p	CLIP-seq
MIRT1235255	hsa-miR-362-3p	CLIP-seq
MIRT1235258	hsa-miR-3665	CLIP-seq
MIRT1235259	hsa-miR-3687	CLIP-seq
MIRT1235261	hsa-miR-3691-3p	CLIP-seq
MIRT1235262	hsa-miR-3714	CLIP-seq
MIRT1235263	hsa-miR-377	CLIP-seq
MIRT1235265	hsa-miR-3922-3p	CLIP-seq
MIRT1235266	hsa-miR-3926	CLIP-seq
MIRT1235267	hsa-miR-3934	CLIP-seq
MIRT2296331	hsa-miR-3974	CLIP-seq
MIRT1235269	hsa-miR-423-5p	CLIP-seq
MIRT1235270	hsa-miR-424	CLIP-seq
MIRT1235272	hsa-miR-4281	CLIP-seq
MIRT1235273	hsa-miR-4286	CLIP-seq
MIRT1235278	hsa-miR-4442	CLIP-seq
MIRT1235279	hsa-miR-4459	CLIP-seq
MIRT1235280	hsa-miR-4465	CLIP-seq
MIRT1235281	hsa-miR-4493	CLIP-seq
MIRT1235282	hsa-miR-4514	CLIP-seq
MIRT2296332	hsa-miR-4640-3p	CLIP-seq
MIRT1235285	hsa-miR-4662a-5p	CLIP-seq
MIRT1235286	hsa-miR-4666-5p	CLIP-seq
MIRT1235287	hsa-miR-4667-5p	CLIP-seq
MIRT1235288	hsa-miR-4685-5p	CLIP-seq
MIRT2296333	hsa-miR-4691-3p	CLIP-seq
MIRT1235289	hsa-miR-4692	CLIP-seq
MIRT1235290	hsa-miR-4700-5p	CLIP-seq
MIRT1235292	hsa-miR-4722-5p	CLIP-seq
MIRT1235294	hsa-miR-4726-3p	CLIP-seq
MIRT1235296	hsa-miR-4736	CLIP-seq
MIRT1235298	hsa-miR-4747-5p	CLIP-seq
MIRT1235299	hsa-miR-4763-5p	CLIP-seq
MIRT2069267	hsa-miR-4768-3p	CLIP-seq
MIRT1235302	hsa-miR-4784	CLIP-seq
MIRT2296334	hsa-miR-493	CLIP-seq
MIRT1235303	hsa-miR-497	CLIP-seq
MIRT2296335	hsa-miR-506	CLIP-seq
MIRT1235307	hsa-miR-516a-3p	CLIP-seq
MIRT1235309	hsa-miR-520d-5p	CLIP-seq
MIRT1235310	hsa-miR-524-5p	CLIP-seq
MIRT2296336	hsa-miR-548an	CLIP-seq
MIRT2069270	hsa-miR-548b-3p	CLIP-seq
MIRT1235314	hsa-miR-548s	CLIP-seq
MIRT1235318	hsa-miR-637	CLIP-seq
MIRT1235322	hsa-miR-764	CLIP-seq
MIRT1235323	hsa-miR-765	CLIP-seq
MIRT2296337	hsa-miR-888	CLIP-seq
MIRT1235212	hsa-miR-1206	CLIP-seq
MIRT1235213	hsa-miR-1226	CLIP-seq
MIRT2296328	hsa-miR-124	CLIP-seq
MIRT1235244	hsa-miR-3182	CLIP-seq
MIRT2296330	hsa-miR-330-3p	CLIP-seq
MIRT1235257	hsa-miR-3660	CLIP-seq
MIRT2296331	hsa-miR-3974	CLIP-seq
MIRT1235271	hsa-miR-4256	CLIP-seq
MIRT1235283	hsa-miR-4526	CLIP-seq
MIRT1235286	hsa-miR-4666-5p	CLIP-seq
MIRT1235295	hsa-miR-4733-3p	CLIP-seq
MIRT2296334	hsa-miR-493	CLIP-seq
MIRT2296335	hsa-miR-506	CLIP-seq
MIRT1235312	hsa-miR-541	CLIP-seq
MIRT2296336	hsa-miR-548an	CLIP-seq
MIRT1235319	hsa-miR-654-5p	CLIP-seq
MIRT2296337	hsa-miR-888	CLIP-seq

Show/Hide all(23)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	18593906
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0005515	Function	Protein binding	IPI	17270021
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0006468	Process	Protein phosphorylation	IDA	18593906
GO:0006915	Process	Apoptotic process	IEA
GO:0007346	Process	Regulation of mitotic cell cycle	IBA
GO:0007346	Process	Regulation of mitotic cell cycle	IMP	17270021
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0043066	Process	Negative regulation of apoptotic process	IBA
GO:0043066	Process	Negative regulation of apoptotic process	IEA
GO:0043066	Process	Negative regulation of apoptotic process	IMP	17270021
GO:0061179	Process	Negative regulation of insulin secretion involved in cellular response to glucose stimulus	IEA
GO:0061179	Process	Negative regulation of insulin secretion involved in cellular response to glucose stimulus	ISS
GO:0106310	Function	Protein serine kinase activity	IEA
GO:1904322	Process	Cellular response to forskolin	IEA

MIM	HGNC	e!Ensembl
610580	19310	ENSG00000198355

Protein

UniProt ID

Q86V86

Protein name

Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)

Protein function

Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which indu

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00069	Pkinase	40 → 293	Protein kinase domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Detected in various tissues, including the heart, brain, lung, kidney, spleen, placenta, skeletal muscle, and peripheral blood leukocytes. Not found or barely expressed in the normal adult endoderm-derived organs such as colon, thymus,

Sequence

MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
ADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFL
LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL
RSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVC
GDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGV
PESCDLRLCTLDPDDVASTTSSSESL

Sequence length

326

Interactions

View interactions

Show/Hide Unknown Diseases (2)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Acne	acne vulgaris	N/A	N/A	GWAS
Diabetes	Type 2 diabetes, Type 2 diabetes (adjusted for BMI)	N/A	N/A	GWAS

Show/Hide Text Mining Associations (25)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenoma	Associate	17270021
Breast Neoplasms	Associate	24818135
Carcinogenesis	Associate	25921139, 26768612
Carcinoma Pancreatic Ductal	Associate	23760491, 25971209
Carcinoma Pancreatic Ductal	Stimulate	37943821
Colorectal Neoplasms	Associate	17270021, 26768612
Esophageal Neoplasms	Associate	24488669
Glioblastoma	Associate	22544323
Hereditary leiomyomatosis and renal cell cancer	Associate	37910143
Hodgkin Disease	Associate	37910143
Leukemia	Associate	31671637
Liposarcoma	Associate	30654529
Lymphatic Metastasis	Associate	24488669, 26768612
Lymphoma	Associate	31671637
Nasopharyngeal Carcinoma	Associate	16308470
Neoplasm Metastasis	Associate	16308470, 26768612, 27826135
Neoplasm Metastasis	Stimulate	25921139
Neoplasms	Associate	17270021, 19154409, 24488669, 24818135, 26768612, 29765150
Neoplasms	Inhibit	22544323
Neuroblastoma	Associate	36907773
Ovarian Neoplasms	Associate	25921139
Pancreatic Neoplasms	Associate	19154409, 23760491, 25971209, 27638830
Prostatic Neoplasms	Associate	27826135, 31730483, 33932111
Rectal Neoplasms	Associate	29167471
Stomach Neoplasms	Associate	29879757

PIM3 (Pim-3 proto-oncogene, serine/threonine kinase)