C10orf105 (chromosome 10 open reading frame 105)

Gene

• Entrez ID: 414152
• Gene name: Chromosome 10 open reading frame 105
• Gene symbol: C10orf105
• Synonyms (NCBI Gene): -
• Chromosome: 10
• Chromosome location: 10q22.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT025760	hsa-miR-7-5p	Microarray	17612493
MIRT716353	hsa-miR-5007-5p	HITS-CLIP	19536157
MIRT716352	hsa-miR-520g-5p	HITS-CLIP	19536157
MIRT716351	hsa-miR-432-5p	HITS-CLIP	19536157
MIRT716350	hsa-miR-539-5p	HITS-CLIP	19536157
MIRT716349	hsa-miR-185-5p	HITS-CLIP	19536157
MIRT716348	hsa-miR-4306	HITS-CLIP	19536157
MIRT716347	hsa-miR-4644	HITS-CLIP	19536157
MIRT716346	hsa-miR-5192	HITS-CLIP	19536157
MIRT716345	hsa-miR-518d-5p	HITS-CLIP	19536157
MIRT716344	hsa-miR-518e-5p	HITS-CLIP	19536157
MIRT716343	hsa-miR-518f-5p	HITS-CLIP	19536157
MIRT716342	hsa-miR-519a-5p	HITS-CLIP	19536157
MIRT716341	hsa-miR-519b-5p	HITS-CLIP	19536157
MIRT716340	hsa-miR-519c-5p	HITS-CLIP	19536157
MIRT716339	hsa-miR-520c-5p	HITS-CLIP	19536157
MIRT716338	hsa-miR-522-5p	HITS-CLIP	19536157
MIRT716337	hsa-miR-523-5p	HITS-CLIP	19536157
MIRT716336	hsa-miR-526a	HITS-CLIP	19536157
MIRT716335	hsa-miR-4777-5p	HITS-CLIP	19536157
MIRT716334	hsa-miR-4531	HITS-CLIP	19536157
MIRT716333	hsa-miR-1270	HITS-CLIP	19536157
MIRT716332	hsa-miR-620	HITS-CLIP	19536157
MIRT526720	hsa-miR-188-5p	PAR-CLIP	22012620
MIRT526719	hsa-miR-6866-3p	PAR-CLIP	22012620
MIRT526718	hsa-miR-5088-3p	PAR-CLIP	22012620
MIRT526717	hsa-miR-5193	PAR-CLIP	22012620
MIRT526716	hsa-miR-3667-3p	PAR-CLIP	22012620
MIRT526715	hsa-miR-676-5p	PAR-CLIP	22012620
MIRT526714	hsa-miR-378a-5p	PAR-CLIP	22012620
MIRT526713	hsa-miR-1200	PAR-CLIP	22012620
MIRT716353	hsa-miR-5007-5p	HITS-CLIP	19536157
MIRT716352	hsa-miR-520g-5p	HITS-CLIP	19536157
MIRT716351	hsa-miR-432-5p	HITS-CLIP	19536157
MIRT716350	hsa-miR-539-5p	HITS-CLIP	19536157
MIRT716349	hsa-miR-185-5p	HITS-CLIP	19536157
MIRT716348	hsa-miR-4306	HITS-CLIP	19536157
MIRT716347	hsa-miR-4644	HITS-CLIP	19536157
MIRT716346	hsa-miR-5192	HITS-CLIP	19536157
MIRT716345	hsa-miR-518d-5p	HITS-CLIP	19536157
MIRT716344	hsa-miR-518e-5p	HITS-CLIP	19536157
MIRT716343	hsa-miR-518f-5p	HITS-CLIP	19536157
MIRT716342	hsa-miR-519a-5p	HITS-CLIP	19536157
MIRT716341	hsa-miR-519b-5p	HITS-CLIP	19536157
MIRT716340	hsa-miR-519c-5p	HITS-CLIP	19536157
MIRT716339	hsa-miR-520c-5p	HITS-CLIP	19536157
MIRT716338	hsa-miR-522-5p	HITS-CLIP	19536157
MIRT716337	hsa-miR-523-5p	HITS-CLIP	19536157
MIRT716336	hsa-miR-526a	HITS-CLIP	19536157
MIRT716335	hsa-miR-4777-5p	HITS-CLIP	19536157
MIRT716334	hsa-miR-4531	HITS-CLIP	19536157
MIRT716333	hsa-miR-1270	HITS-CLIP	19536157
MIRT716332	hsa-miR-620	HITS-CLIP	19536157
MIRT526720	hsa-miR-188-5p	PAR-CLIP	22012620
MIRT526719	hsa-miR-6866-3p	PAR-CLIP	22012620
MIRT526718	hsa-miR-5088-3p	PAR-CLIP	22012620
MIRT526717	hsa-miR-5193	PAR-CLIP	22012620
MIRT526716	hsa-miR-3667-3p	PAR-CLIP	22012620
MIRT526715	hsa-miR-676-5p	PAR-CLIP	22012620
MIRT526714	hsa-miR-378a-5p	PAR-CLIP	22012620
MIRT526713	hsa-miR-1200	PAR-CLIP	22012620
MIRT828102	hsa-miR-1184	CLIP-seq
MIRT828103	hsa-miR-1205	CLIP-seq
MIRT828104	hsa-miR-1271	CLIP-seq
MIRT828105	hsa-miR-1286	CLIP-seq
MIRT828106	hsa-miR-1287	CLIP-seq
MIRT828107	hsa-miR-1289	CLIP-seq
MIRT828108	hsa-miR-1299	CLIP-seq
MIRT828109	hsa-miR-1302	CLIP-seq
MIRT828110	hsa-miR-146b-3p	CLIP-seq
MIRT828111	hsa-miR-182	CLIP-seq
MIRT828112	hsa-miR-224	CLIP-seq
MIRT828113	hsa-miR-2467-3p	CLIP-seq
MIRT828114	hsa-miR-3064-3p	CLIP-seq
MIRT828115	hsa-miR-3121-5p	CLIP-seq
MIRT828116	hsa-miR-3122	CLIP-seq
MIRT828117	hsa-miR-3125	CLIP-seq
MIRT828118	hsa-miR-3135b	CLIP-seq
MIRT828119	hsa-miR-3158-5p	CLIP-seq
MIRT828120	hsa-miR-3173-5p	CLIP-seq
MIRT828121	hsa-miR-3182	CLIP-seq
MIRT828122	hsa-miR-3198	CLIP-seq
MIRT828123	hsa-miR-324-5p	CLIP-seq
MIRT828124	hsa-miR-3616-3p	CLIP-seq
MIRT828125	hsa-miR-3649	CLIP-seq
MIRT828126	hsa-miR-365	CLIP-seq
MIRT828127	hsa-miR-3678-3p	CLIP-seq
MIRT828128	hsa-miR-3913-5p	CLIP-seq
MIRT828129	hsa-miR-3916	CLIP-seq
MIRT828130	hsa-miR-4254	CLIP-seq
MIRT828131	hsa-miR-4267	CLIP-seq
MIRT828132	hsa-miR-4294	CLIP-seq
MIRT828133	hsa-miR-4298	CLIP-seq
MIRT828134	hsa-miR-4309	CLIP-seq
MIRT828135	hsa-miR-4476	CLIP-seq
MIRT828136	hsa-miR-4509	CLIP-seq
MIRT828137	hsa-miR-4527	CLIP-seq
MIRT828138	hsa-miR-4659a-5p	CLIP-seq
MIRT828139	hsa-miR-4659b-5p	CLIP-seq
MIRT828140	hsa-miR-4708-3p	CLIP-seq
MIRT828141	hsa-miR-4715-3p	CLIP-seq
MIRT828142	hsa-miR-4776-3p	CLIP-seq
MIRT828143	hsa-miR-4782-5p	CLIP-seq
MIRT828144	hsa-miR-513a-3p	CLIP-seq
MIRT828145	hsa-miR-516b	CLIP-seq
MIRT828146	hsa-miR-518a-5p	CLIP-seq
MIRT828147	hsa-miR-527	CLIP-seq
MIRT828148	hsa-miR-619	CLIP-seq
MIRT828149	hsa-miR-766	CLIP-seq
MIRT828150	hsa-miR-874	CLIP-seq
MIRT828151	hsa-miR-875-3p	CLIP-seq
MIRT828152	hsa-miR-96	CLIP-seq
MIRT828153	hsa-miR-103a	CLIP-seq
MIRT828154	hsa-miR-107	CLIP-seq
MIRT828102	hsa-miR-1184	CLIP-seq
MIRT828155	hsa-miR-1321	CLIP-seq
MIRT828156	hsa-miR-1909	CLIP-seq
MIRT828157	hsa-miR-1915	CLIP-seq
MIRT828158	hsa-miR-3065-3p	CLIP-seq
MIRT828159	hsa-miR-3591-5p	CLIP-seq
MIRT828160	hsa-miR-3921	CLIP-seq
MIRT828161	hsa-miR-4255	CLIP-seq
MIRT828162	hsa-miR-4270	CLIP-seq
MIRT828163	hsa-miR-4271	CLIP-seq
MIRT828164	hsa-miR-4441	CLIP-seq
MIRT828165	hsa-miR-4460	CLIP-seq
MIRT828166	hsa-miR-452	CLIP-seq
MIRT828167	hsa-miR-4653-5p	CLIP-seq
MIRT828168	hsa-miR-4676-3p	CLIP-seq
MIRT828169	hsa-miR-4725-3p	CLIP-seq
MIRT828170	hsa-miR-4727-3p	CLIP-seq
MIRT828171	hsa-miR-4739	CLIP-seq
MIRT828172	hsa-miR-4756-5p	CLIP-seq
MIRT828173	hsa-miR-539	CLIP-seq
MIRT828174	hsa-miR-593	CLIP-seq
MIRT828175	hsa-miR-596	CLIP-seq
MIRT828176	hsa-miR-665	CLIP-seq
MIRT828177	hsa-miR-7	CLIP-seq
MIRT828102	hsa-miR-1184	CLIP-seq
MIRT1945021	hsa-miR-1233	CLIP-seq
MIRT828105	hsa-miR-1286	CLIP-seq
MIRT1945022	hsa-miR-129-3p	CLIP-seq
MIRT828109	hsa-miR-1302	CLIP-seq
MIRT1945023	hsa-miR-2392	CLIP-seq
MIRT1945024	hsa-miR-3074-5p	CLIP-seq
MIRT828116	hsa-miR-3122	CLIP-seq
MIRT1945025	hsa-miR-3150a-3p	CLIP-seq
MIRT1945026	hsa-miR-3173-3p	CLIP-seq
MIRT1945027	hsa-miR-3175	CLIP-seq
MIRT1945028	hsa-miR-3202	CLIP-seq
MIRT828125	hsa-miR-3649	CLIP-seq
MIRT828128	hsa-miR-3913-5p	CLIP-seq
MIRT828133	hsa-miR-4298	CLIP-seq
MIRT1945029	hsa-miR-450a	CLIP-seq
MIRT1945030	hsa-miR-4533	CLIP-seq
MIRT1945031	hsa-miR-4640-5p	CLIP-seq
MIRT1945032	hsa-miR-4726-5p	CLIP-seq
MIRT1945033	hsa-miR-4728-5p	CLIP-seq
MIRT1945034	hsa-miR-4731-5p	CLIP-seq
MIRT1945035	hsa-miR-4755-3p	CLIP-seq
MIRT1945036	hsa-miR-491-5p	CLIP-seq
MIRT1945037	hsa-miR-515-3p	CLIP-seq
MIRT1945038	hsa-miR-519e	CLIP-seq
MIRT1945039	hsa-miR-574-5p	CLIP-seq
MIRT1945040	hsa-miR-939	CLIP-seq
MIRT2183510	hsa-miR-31	CLIP-seq
MIRT828116	hsa-miR-3122	CLIP-seq
MIRT1945025	hsa-miR-3150a-3p	CLIP-seq
MIRT1945027	hsa-miR-3175	CLIP-seq
MIRT2183511	hsa-miR-3688-5p	CLIP-seq
MIRT828128	hsa-miR-3913-5p	CLIP-seq
MIRT2183512	hsa-miR-4419a	CLIP-seq
MIRT2183513	hsa-miR-4487	CLIP-seq
MIRT2183514	hsa-miR-450b-3p	CLIP-seq
MIRT2183515	hsa-miR-4510	CLIP-seq
MIRT2183516	hsa-miR-4633-3p	CLIP-seq
MIRT2183517	hsa-miR-4667-5p	CLIP-seq
MIRT2183518	hsa-miR-4700-5p	CLIP-seq
MIRT1945034	hsa-miR-4731-5p	CLIP-seq
MIRT2183519	hsa-miR-607	CLIP-seq
MIRT828177	hsa-miR-7	CLIP-seq
MIRT2183520	hsa-miR-769-3p	CLIP-seq
MIRT1945040	hsa-miR-939	CLIP-seq
MIRT2487165	hsa-miR-3922-5p	CLIP-seq
MIRT828140	hsa-miR-4708-3p	CLIP-seq
MIRT2487166	hsa-miR-4773	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0016020	Component	Membrane	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8TEF2
• Protein name: Uncharacterized protein C10orf105
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF17665	DUF5527	1 → 133	Family of unknown function (DUF5527)	Family

• Sequence:

  MSTEGPSLASSPAISPLAFLSAPVTPGTLAEATDPLPMLIALACIFLLLATCLLFMTLCK
  PAALDPSRRRAHECMPHHPGSPSEPQLRLWKRLGSLRLSLHSFRHGRPTVPRQPLPGPED
  NRSHCDYMESTKM

• Sequence length: 133

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
DEAFNESS, AUTOSOMAL RECESSIVE	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEAFNESS, AUTOSOMAL RECESSIVE 12	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEARING IMPAIRMENT	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HEARING LOSS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MENIERE DISEASE	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RETINITIS PIGMENTOSA-DEAFNESS SYNDROME	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
USHER SYNDROME	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
USHER SYNDROME, TYPE I	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
USHER SYNDROME, TYPE ID	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VITREORETINAL DEGENERATION	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations