MAGEA6 (MAGE family member A6)

Gene
Gene miRNA Gene ontology Other IDs Protein
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
4105
Gene name Gene Name - the full gene name approved by the HGNC.
MAGE family member A6
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MAGEA6
Synonyms (NCBI Gene) Gene synonyms aliases
CT1.6, MAGE-3b, MAGE3B, MAGE6
Chromosome Chromosome number
X
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
Xq28
Summary Summary of gene provided in NCBI Entrez Gene.
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of thi
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein
Show/Hide all(11)
miRTarBase ID miRNA Experiments Reference
MIRT004110 hsa-miR-34a-5p Immunocytochemistry, Luciferase reporter assay, qRT-PCR, Western blot 21177782
MIRT004110 hsa-miR-34a-5p Immunocytochemistry, Luciferase reporter assay, qRT-PCR, Western blot 21177782
MIRT027491 hsa-miR-98-5p Microarray 19088304
MIRT027491 hsa-miR-98-5p PAR-CLIP 27292025
MIRT027491 hsa-miR-98-5p PAR-CLIP 27292025
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein
Show/Hide all(4)
GO ID Ontology Definition Evidence Reference
GO:0003674 Function Molecular_function ND
GO:0005515 Function Protein binding IPI 20864041, 21516116, 25416956, 25910212, 26871637, 31515488, 32296183, 32814053
GO:0005575 Component Cellular_component ND
GO:0008150 Process Biological_process ND
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein
MIM HGNC e!Ensembl
300176 6804 ENSG00000197172
Protein
Gene miRNA Gene ontology Other IDs Protein
UniProt ID P43360
Protein name Melanoma-associated antigen 6 (Cancer/testis antigen 1.6) (CT1.6) (MAGE-6 antigen) (MAGE3B antigen)
Protein function Activator of ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases that acts as a repressor of autophagy (PubMed:17942928, PubMed:20864041, PubMed:31267705). May enhance ubiquitin ligase activity of TRIM28 an
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF12440 MAGE_N 5 → 96 Melanoma associated antigen family N terminal Family
PF01454 MAGE 185 → 283 MAGE family Family
Tissue specificity TISSUE SPECIFICITY: Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes.
Sequence
Sequence length 314
Interactions View interactions