MARCKS (myristoylated alanine rich protein kinase C substrate)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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4082 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Myristoylated alanine rich protein kinase C substrate |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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MARCKS |
Synonyms (NCBI Gene)
Gene synonyms aliases
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80K-L, MACS, PKCSL, PRKCSL |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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MACS |
Chromosome
Chromosome number
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6 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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6q21 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | P29966 | ||||||||||
Protein name | Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL) | ||||||||||
Protein function | Membrane-associated protein that plays a role in the structural modulation of the actin cytoskeleton, chemotaxis, motility, cell adhesion, phagocytosis, and exocytosis through lipid sequestering and/or protein docking to membranes (PubMed:237049 | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Detected in spermatozoa. {ECO:0000269|PubMed:23704996}. | ||||||||||
Sequence |
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Sequence length | 332 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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