MIR98 (microRNA 98)

Gene

• Entrez ID: 407054
• Gene name: MicroRNA 98
• Gene symbol: MIR98
• Synonyms (NCBI Gene): MIRLET7L, MIRN98, hsa-mir-98, miR-98
• Chromosome: X
• Chromosome location: Xp11.22
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001818	Process	Negative regulation of cytokine production	IDA	27860183
GO:0003730	Function	MRNA 3'-UTR binding	IDA	22492871, 27860183, 31886314
GO:0005615	Component	Extracellular space	HDA	26646931
GO:0008285	Process	Negative regulation of cell population proliferation	IDA	31886314
GO:0010629	Process	Negative regulation of gene expression	IDA	31886314
GO:0010629	Process	Negative regulation of gene expression	IMP	27860183
GO:0010716	Process	Negative regulation of extracellular matrix disassembly	IDA	26587789
GO:0016442	Component	RISC complex	IEA
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	IMP	28251559
GO:0030514	Process	Negative regulation of BMP signaling pathway	IMP	27860183
GO:0032691	Process	Negative regulation of interleukin-1 beta production	IDA	31886314
GO:0032693	Process	Negative regulation of interleukin-10 production	IDA	29702181, 31886314
GO:0032693	Process	Negative regulation of interleukin-10 production	IDA	29702181
GO:0032715	Process	Negative regulation of interleukin-6 production	IDA	31886314
GO:0032717	Process	Negative regulation of interleukin-8 production	IDA	31886314
GO:0032720	Process	Negative regulation of tumor necrosis factor production	IDA	31886314
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	22492871, 26098770, 26587789, 29702181, 31886314
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IDA	27541017
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	27860183, 30195495
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IMP	28251559
GO:0043525	Process	Positive regulation of neuron apoptotic process	IMP	27541017
GO:0045541	Process	Negative regulation of cholesterol biosynthetic process	IDA	30195495
GO:0045668	Process	Negative regulation of osteoblast differentiation	IMP	27860183
GO:0070104	Process	Negative regulation of interleukin-6-mediated signaling pathway	IDA	26587789
GO:0070104	Process	Negative regulation of interleukin-6-mediated signaling pathway	IGI	31886314
GO:1900015	Process	Regulation of cytokine production involved in inflammatory response	IDA	29702181
GO:1900016	Process	Negative regulation of cytokine production involved in inflammatory response	IDA	31886314
GO:1901202	Process	Negative regulation of extracellular matrix assembly	IMP	28251559
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	22492871, 26098770, 26587789, 27541017, 27860183, 29702181, 30195495, 31886314
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IMP	28251559
GO:1904646	Process	Cellular response to amyloid-beta	IMP	27541017
GO:1904761	Process	Negative regulation of myofibroblast differentiation	IMP	28251559
GO:1905563	Process	Negative regulation of vascular endothelial cell proliferation	IDA	26098770

Other IDs

• MIM: 300810
• HGNC: 31649
• e!Ensembl: ENSG00000271886

Interactions View interactions