MIR92A1 (microRNA 92a-1)

Gene

• Entrez ID: 407048
• Gene name: MicroRNA 92a-1
• Gene symbol: MIR92A1
• Synonyms (NCBI Gene): C13orf25, MIR17HG, MIR92-1, MIRH1, MIRHG1, MIRN92-1, MIRN92A-1, MIRN92A1, miRNA92-1, mir-92a-1
• Chromosome: 13
• Chromosome location: 13q31.3
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001937	Process	Negative regulation of endothelial cell proliferation	IDA	19460962
GO:0002675	Process	Positive regulation of acute inflammatory response	ISS
GO:0003730	Function	MRNA 3'-UTR binding	IDA	24378993
GO:0005615	Component	Extracellular space	HDA	18766170, 26646931
GO:0005737	Component	Cytoplasm	IDA	25336585
GO:0008016	Process	Regulation of heart contraction	ISS
GO:0010628	Process	Positive regulation of gene expression	IDA	24026406, 24255059
GO:0010628	Process	Positive regulation of gene expression	IMP	22267480
GO:0010629	Process	Negative regulation of gene expression	IMP	20484043, 22267480
GO:0010716	Process	Negative regulation of extracellular matrix disassembly	IMP	23820254
GO:0016442	Component	RISC complex	IEA
GO:0016525	Process	Negative regulation of angiogenesis	ISS
GO:0032755	Process	Positive regulation of interleukin-6 production	IDA	24255059
GO:0032966	Process	Negative regulation of collagen biosynthetic process	ISS
GO:0034392	Process	Negative regulation of smooth muscle cell apoptotic process	ISS
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	19460962, 20660482, 21148309, 21768538, 21796614, 22267480, 23308108, 24026406, 24255059, 24332650, 24375836, 24378993, 26299712
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IMP	20484043, 22895567, 23622248, 24255059
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IDA	23820254, 24026406
GO:0043065	Process	Positive regulation of apoptotic process	ISS
GO:0043537	Process	Negative regulation of blood vessel endothelial cell migration	IDA	19460962
GO:0045019	Process	Negative regulation of nitric oxide biosynthetic process	IMP	21768538
GO:0046329	Process	Negative regulation of JNK cascade	ISS
GO:0046330	Process	Positive regulation of JNK cascade	IDA	24332650
GO:0050728	Process	Negative regulation of inflammatory response	IMP	22267480
GO:0050729	Process	Positive regulation of inflammatory response	ISS
GO:0062100	Process	Positive regulation of programmed necrotic cell death	ISS
GO:0071398	Process	Cellular response to fatty acid	ISS
GO:0071404	Process	Cellular response to low-density lipoprotein particle stimulus	IDA	24255059
GO:0071639	Process	Positive regulation of monocyte chemotactic protein-1 production	IDA	24255059
GO:0097533	Process	Cellular stress response to acid chemical	IDA	26299712
GO:0097699	Process	Vascular endothelial cell response to fluid shear stress	IDA	24255059
GO:0097746	Process	Blood vessel diameter maintenance	ISS
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	19460962, 20660482, 21148309, 21768538, 21796614, 22267480, 23308108, 23820254, 24026406, 24255059, 24332650, 24375836, 24378993, 26299712
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IMP	20484043, 22895567, 23622248
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1903671	Process	Negative regulation of sprouting angiogenesis	IDA	19460962
GO:1903672	Process	Positive regulation of sprouting angiogenesis	IDA	26299712
GO:1903751	Process	Negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide	ISS
GO:1904905	Process	Negative regulation of endothelial cell-matrix adhesion via fibronectin	IDA	19460962
GO:1904989	Process	Positive regulation of endothelial cell activation	IC	24255059
GO:1904996	Process	Positive regulation of leukocyte adhesion to vascular endothelial cell	IDA	24255059
GO:1904996	Process	Positive regulation of leukocyte adhesion to vascular endothelial cell	IMP	23897866
GO:1904999	Process	Positive regulation of leukocyte adhesion to arterial endothelial cell	IMP	22267480

Other IDs

• MIM: 609422
• HGNC: 31643
• e!Ensembl: ENSG00000283705

Interactions View interactions

Pathways

KEGG:

MicroRNAs in cancer