MIR29C (microRNA 29c)

Gene

• Entrez ID: 407026
• Gene name: MicroRNA 29c
• Gene symbol: MIR29C
• Synonyms (NCBI Gene): MIRN29C, miRNA29C, mir-29c
• Chromosome: 1
• Chromosome location: 1q32.2
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001953	Process	Negative regulation of cell-matrix adhesion	IDA	23936390
GO:0003730	Function	MRNA 3'-UTR binding	IDA	21565331, 25605017, 25973041, 26766915
GO:0005615	Component	Extracellular space	HDA	26646931
GO:0005739	Component	Mitochondrion	IEA
GO:0008285	Process	Negative regulation of cell population proliferation	IDA	20086245, 24091622, 24130168
GO:0010629	Process	Negative regulation of gene expression	IDA	20570858, 26175848
GO:0010716	Process	Negative regulation of extracellular matrix disassembly	IDA	23936390
GO:0016442	Component	RISC complex	IEA
GO:0016525	Process	Negative regulation of angiogenesis	IDA	26175848
GO:0030336	Process	Negative regulation of cell migration	IDA	23936390, 25605017
GO:0030336	Process	Negative regulation of cell migration	IDA	24091622, 24130168, 25428377
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	18390668, 20041405, 20086245, 20570858, 22745231, 23857059, 23936390, 24091622, 24130168, 24578160, 25428377, 25605017, 25973041, 26045889, 26175848, 26687115, 26766915
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IDA	21565331
GO:0040029	Process	Epigenetic regulation of gene expression	IDA	23857059
GO:0043065	Process	Positive regulation of apoptotic process	IDA	20041405, 24130168
GO:0043569	Process	Negative regulation of insulin-like growth factor receptor signaling pathway	IDA	26045889, 26175848
GO:0051898	Process	Negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IDA	25428377
GO:0061754	Process	Negative regulation of circulating fibrinogen levels	IDA	20570858
GO:0070062	Component	Extracellular exosome	IDA	28159509
GO:0090051	Process	Negative regulation of cell migration involved in sprouting angiogenesis	IDA	26045889, 26175848
GO:0090090	Process	Negative regulation of canonical Wnt signaling pathway	IDA	25605017
GO:1902110	Process	Positive regulation of mitochondrial membrane permeability involved in apoptotic process	IDA	20041405
GO:1902430	Process	Negative regulation of amyloid-beta formation	IC	21565331
GO:1902430	Process	Negative regulation of amyloid-beta formation	IDA	25973041
GO:1902807	Process	Negative regulation of cell cycle G1/S phase transition	IDA	26045889
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	18390668, 20041405, 20086245, 20570858, 21565331, 22745231, 23857059, 23936390, 24091622, 24130168, 24578160, 25428377, 25605017, 25973041, 26045889, 26175848, 26687115, 26766915
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1903588	Process	Negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	IDA	26045889
GO:1905563	Process	Negative regulation of vascular endothelial cell proliferation	IDA	26175848
GO:2000134	Process	Negative regulation of G1/S transition of mitotic cell cycle	IDA	24130168

Other IDs

• MIM: 610784
• HGNC: 31621
• e!Ensembl: ENSG00000284214

Interactions View interactions

Pathways

KEGG:

MicroRNAs in cancer
Chemical carcinogenesis - receptor activation