MIR29A (microRNA 29a)

Gene

• Entrez ID: 407021
• Gene name: MicroRNA 29a
• Gene symbol: MIR29A
• Synonyms (NCBI Gene): MIRN29, MIRN29A, hsa-mir-29, hsa-mir-29a, miRNA29A, mir-29a
• Chromosome: 7
• Chromosome location: 7q32.3
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003730	Function	MRNA 3'-UTR binding	IDA	18434550, 25058496, 26903137, 28342862
GO:0005615	Component	Extracellular space	HDA	26646931
GO:0005737	Component	Cytoplasm	IDA	17204650
GO:0005739	Component	Mitochondrion	IEA
GO:0008285	Process	Negative regulation of cell population proliferation	IDA	24091622, 24130168, 24209632, 25171863
GO:0010595	Process	Positive regulation of endothelial cell migration	IDA	23426367
GO:0010628	Process	Positive regulation of gene expression	IDA	21573166
GO:0010629	Process	Negative regulation of gene expression	IDA	20570858
GO:0016442	Component	RISC complex	IEA
GO:0016525	Process	Negative regulation of angiogenesis	IDA	28637396
GO:0030335	Process	Positive regulation of cell migration	IDA	21573166
GO:0030336	Process	Negative regulation of cell migration	IDA	24091622, 24130168, 24210072, 25171863, 25428377
GO:0032966	Process	Negative regulation of collagen biosynthetic process	IDA	20067797
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	18434550, 20041405, 20067797, 20086245, 20570858, 21573166, 21761362, 22745231, 23541945, 23857059, 24091622, 24130168, 24209632, 24210072, 24578160, 25171863, 25428377, 26687115, 26820803, 26903137, 28342862, 28637396, 31694982
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IMP	25058496
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IDA	19584290
GO:0040029	Process	Epigenetic regulation of gene expression	IDA	23857059
GO:0043065	Process	Positive regulation of apoptotic process	IDA	20041405, 24130168, 24210072
GO:0045742	Process	Positive regulation of epidermal growth factor receptor signaling pathway	IMP	25058496
GO:0045766	Process	Positive regulation of angiogenesis	IDA	23426367, 23541945
GO:0051897	Process	Positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IDA	21573166
GO:0051898	Process	Negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IDA	25428377
GO:0061754	Process	Negative regulation of circulating fibrinogen levels	IDA	20570858
GO:0070062	Component	Extracellular exosome	IDA	28159509
GO:0090303	Process	Positive regulation of wound healing	IMP	25058496
GO:0106222	Function	LncRNA binding	IDA	31694982
GO:1900087	Process	Positive regulation of G1/S transition of mitotic cell cycle	IDA	23541945
GO:1902110	Process	Positive regulation of mitochondrial membrane permeability involved in apoptotic process	IDA	20041405
GO:1902430	Process	Negative regulation of amyloid-beta formation	IDA	18434550
GO:1902992	Process	Negative regulation of amyloid precursor protein catabolic process	IDA	18434550
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	18434550, 19584290, 20041405, 20067797, 21573166, 21761362, 22745231, 23541945, 23857059, 24091622, 24130168, 24209632, 24210072, 24578160, 25058496, 25171863, 25428377, 26687115, 26820803, 26903137, 28342862, 31694982
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1905564	Process	Positive regulation of vascular endothelial cell proliferation	IDA	23541945
GO:2000134	Process	Negative regulation of G1/S transition of mitotic cell cycle	IDA	24130168

Other IDs

• MIM: 610782
• HGNC: 31616
• e!Ensembl: ENSG00000284032

Interactions View interactions

Pathways

KEGG:

MicroRNAs in cancer
Chemical carcinogenesis - receptor activation