MIR24-1 (microRNA 24-1)

Gene

• Entrez ID: 407012
• Gene name: MicroRNA 24-1
• Gene symbol: MIR24-1
• Synonyms (NCBI Gene): MIR189, MIRN24-1, miR-24-1, miRNA24-1
• Chromosome: 9
• Chromosome location: 9q22.32
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003730	Function	MRNA 3'-UTR binding	IDA	25100943, 29457789
GO:0005615	Component	Extracellular space	HDA	18766170
GO:0005615	Component	Extracellular space	IDA	26646931
GO:0008285	Process	Negative regulation of cell population proliferation	IGI	28337997
GO:0010667	Process	Negative regulation of cardiac muscle cell apoptotic process	ISS
GO:0010716	Process	Negative regulation of extracellular matrix disassembly	ISS
GO:0010804	Process	Negative regulation of tumor necrosis factor-mediated signaling pathway	ISS
GO:0016442	Component	RISC complex	IEA
GO:0016525	Process	Negative regulation of angiogenesis	IDA	21788589
GO:0016525	Process	Negative regulation of angiogenesis	IDA	23774796
GO:0030336	Process	Negative regulation of cell migration	IGI	28337997
GO:0032689	Process	Negative regulation of type II interferon production	IDA	24704866
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	15131085, 21788589, 23774796, 23836801, 23874542, 24704866, 25100943, 27983982, 29457789
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IMP	23774796
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IDA	28337997
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IMP	30378100
GO:0043537	Process	Negative regulation of blood vessel endothelial cell migration	IDA	21788589
GO:0045668	Process	Negative regulation of osteoblast differentiation	IMP	30378100
GO:0061049	Process	Cell growth involved in cardiac muscle cell development	ISS
GO:0070062	Component	Extracellular exosome	IDA	28159509, 31926946
GO:0070374	Process	Positive regulation of ERK1 and ERK2 cascade	ISS
GO:1902430	Process	Negative regulation of amyloid-beta formation	IDA	25100943
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	15131085, 21788589, 23774796, 23874542, 24704866, 25100943, 27983982, 28337997, 29457789
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IMP	23836801, 30378100
GO:1903428	Process	Positive regulation of reactive oxygen species biosynthetic process	IDA	21788589
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1903588	Process	Negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	IDA	21788589
GO:1903783	Process	Negative regulation of sodium ion import across plasma membrane	IDA	29457789
GO:1905461	Process	Positive regulation of vascular associated smooth muscle cell apoptotic process	IDA	23774796
GO:1905522	Process	Negative regulation of macrophage migration	ISS
GO:1905563	Process	Negative regulation of vascular endothelial cell proliferation	IDA	23774796
GO:2000270	Process	Negative regulation of fibroblast apoptotic process	ISS
GO:2000353	Process	Positive regulation of endothelial cell apoptotic process	IDA	21788589

Other IDs

• MIM: 609705
• HGNC: 31607
• e!Ensembl: ENSG00000284459

Interactions View interactions