MIR23A (microRNA 23a)

Gene

• Entrez ID: 407010
• Gene name: MicroRNA 23a
• Gene symbol: MIR23A
• Synonyms (NCBI Gene): MIRN23A, hsa-mir-23a, miRNA23A, mir-23a
• Chromosome: 19
• Chromosome location: 19p13.12
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003730	Function	MRNA 3'-UTR binding	IDA	26400397, 29771433, 31281935
GO:0005615	Component	Extracellular space	HDA	18766170, 26646931
GO:0008285	Process	Negative regulation of cell population proliferation	IDA	29771433
GO:0010628	Process	Positive regulation of gene expression	IGI	26400397
GO:0016442	Component	RISC complex	IEA
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	15131085, 24498188, 27741223, 29771433, 31281935
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IGI	21536891
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	26400397
GO:0035924	Process	Cellular response to vascular endothelial growth factor stimulus	IGI	21536891
GO:0043065	Process	Positive regulation of apoptotic process	IDA	29771433
GO:0043065	Process	Positive regulation of apoptotic process	IGI	26400397
GO:0043116	Process	Negative regulation of vascular permeability	IDA	27741223
GO:0060392	Process	Negative regulation of SMAD protein signal transduction	IMP	26400397
GO:0061049	Process	Cell growth involved in cardiac muscle cell development	ISS
GO:0070062	Component	Extracellular exosome	IDA	28159509, 31926946
GO:0070374	Process	Positive regulation of ERK1 and ERK2 cascade	IGI	21536891
GO:0090050	Process	Positive regulation of cell migration involved in sprouting angiogenesis	IGI	21536891
GO:1902046	Process	Positive regulation of Fas signaling pathway	IGI	26400397
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	15131085, 24498188, 26400397, 27741223, 29771433, 31281935
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IGI	21536891
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1903589	Process	Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	IGI	21536891
GO:1903670	Process	Regulation of sprouting angiogenesis	IDA	27741223

Other IDs

• MIM: 607962
• HGNC: 31605
• e!Ensembl: ENSG00000207980

Interactions View interactions

Pathways

KEGG:

MicroRNAs in cancer