MIR224 (microRNA 224)

Gene
Gene Gene ontology Other IDs Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
407009
Gene name Gene Name - the full gene name approved by the HGNC.
MicroRNA 224
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MIR224
Synonyms (NCBI Gene) Gene synonyms aliases
MIRN224, miRNA224
Chromosome Chromosome number
X
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
Xq28
Summary Summary of gene provided in NCBI Entrez Gene.
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Pathways Associated diseases
Show/Hide all(10)
GO ID Ontology Definition Evidence Reference
GO:0003730 Function MRNA 3'-UTR binding IDA 20023705
GO:0016055 Process Wnt signaling pathway IEA
GO:0016442 Component RISC complex IEA
GO:0030336 Process Negative regulation of cell migration IDA 20023705
GO:0035195 Process MiRNA-mediated post-transcriptional gene silencing IDA 20023705
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Pathways Associated diseases
MIM HGNC e!Ensembl
300769 31604 ENSG00000284363
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene Gene ontology Other IDs Pathways Associated diseases
  KEGG  
  MicroRNAs in cancer  
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene Gene ontology Other IDs Pathways Associated diseases
Show/Hide Unknown Diseases (1)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Prostate cancer Prostate cancer miRNA (miR)?205, miR?221, miR?222, miR?30c, miR?224, miR?455?3p, miR?23b and miR?505 were downregulated in patients with prostate cancer (PCa) and were experimentally validated to function as tumor suppressors in prostate cancer cells, affecting tumor pro 32901864 CBGDA
Show/Hide Text Mining Associations (81)
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Adenocarcinoma Associate 25631748, 31164411
Amyotrophic Lateral Sclerosis Associate 37531027
Aphasia Associate 29713155
Atherosclerosis Associate 24676100
Behcet Syndrome Associate 34665700, 34844932
Breast Neoplasms Associate 30594253, 30886656, 33919884, 34076992
Cancer Familial with In Vitro Radioresistance Associate 33992122
Carcinogenesis Associate 18319255, 23667495, 25068270, 25410592, 28055015, 30886656, 34076992
Carcinoma Hepatocellular Associate 18319255, 22459148, 23988648, 25068270, 25688365, 26167081, 26206264, 26231037, 26646011, 27462777, 29534065, 30504786, 31057302, 32236623
Carcinoma Hepatocellular Stimulate 20815808, 26380927, 30411298, 31450927, 31658041