MIR223 (microRNA 223)

Gene

• Entrez ID: 407008
• Gene name: MicroRNA 223
• Gene symbol: MIR223
• Synonyms (NCBI Gene): MIRN223, miRNA223, mir-223
• Chromosome: X
• Chromosome location: Xq12
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001666	Process	Response to hypoxia	IDA	27121304
GO:0003730	Function	MRNA 3'-UTR binding	IDA	34637033
GO:0005615	Component	Extracellular space	HDA	18766170, 26646931
GO:0005615	Component	Extracellular space	IDA	26646931, 27121304
GO:0006954	Process	Inflammatory response	IMP	34637033
GO:0010628	Process	Positive regulation of gene expression	IDA	20080987
GO:0010987	Process	Negative regulation of high-density lipoprotein particle clearance	IDA	23459944
GO:0016442	Component	RISC complex	IEA
GO:0035024	Process	Negative regulation of Rho protein signal transduction	IDA	27121304
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	27121304, 31525642
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	23459944, 30807577, 34637033
GO:0042742	Process	Defense response to bacterium	ISS
GO:0045649	Process	Regulation of macrophage differentiation	ISS
GO:0046326	Process	Positive regulation of D-glucose import	IDA	20080987
GO:0048471	Component	Perinuclear region of cytoplasm	ISS
GO:0050728	Process	Negative regulation of inflammatory response	ISS
GO:0060546	Process	Negative regulation of necroptotic process	ISS
GO:0070062	Component	Extracellular exosome	IDA	31926946
GO:0071222	Process	Cellular response to lipopolysaccharide	IMP	34637033
GO:0090024	Process	Negative regulation of neutrophil chemotaxis	ISS
GO:0106222	Function	LncRNA binding	IDA	31525642
GO:0160028	Process	Negative regulation of pyroptotic inflammatory response	IMP	34637033
GO:1901223	Process	Negative regulation of non-canonical NF-kappaB signal transduction	ISS
GO:1901342	Process	Regulation of vasculature development	IDA	27121304
GO:1903078	Process	Positive regulation of protein localization to plasma membrane	IDA	20080987
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	23459944, 27121304, 30807577, 31525642, 34637033
GO:1904706	Process	Negative regulation of vascular associated smooth muscle cell proliferation	IDA	27121304
GO:1904753	Process	Negative regulation of vascular associated smooth muscle cell migration	IDA	27121304
GO:2001198	Process	Regulation of dendritic cell differentiation	ISS

Other IDs

• MIM: 300694
• HGNC: 31603
• e!Ensembl: ENSG00000284567

Interactions View interactions

Pathways

KEGG:

MicroRNAs in cancer