Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
407007
Gene name Gene Name - the full gene name approved by the HGNC.
MicroRNA 222
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MIR222
Synonyms (NCBI Gene) Gene synonyms aliases
MIRN222, miRNA222, mir-222
Chromosome Chromosome number
X
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
Xp11.3
Summary Summary of gene provided in NCBI Entrez Gene.
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005615 Component Extracellular space HDA 18766170, 26646931
GO:0010634 Process Positive regulation of epithelial cell migration IGI 21673316
GO:0010718 Process Positive regulation of epithelial to mesenchymal transition IGI 21673316
GO:0016442 Component RISC complex IEA
GO:0016525 Process Negative regulation of angiogenesis IDA 20489169
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
300569 31602 ENSG00000207725
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  MicroRNAs in cancer  
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Prostate cancer Prostate cancer miRNA (miR)?205, miR?221, miR?222, miR?30c, miR?224, miR?455?3p, miR?23b and miR?505 were downregulated in patients with prostate cancer (PCa) and were experimentally validated to function as tumor suppressors in prostate cancer cells, affecting tumor pro 32901864 CBGDA
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Abortion Habitual Associate 32224893
Adenocarcinoma Follicular Associate 23563786
Adenocarcinoma of Lung Associate 28617551, 34240140
Alzheimer Disease Associate 31691877
Anophthalmia with pulmonary hypoplasia Associate 22114139
Aortic Aneurysm Thoracic Stimulate 35563123
Arthritis Rheumatoid Associate 27834806, 38241560
Arthritis Rheumatoid Stimulate 31638197
Ascites Associate 29360196
Asymptomatic Infections Associate 36147570