MIR222 (microRNA 222)

Gene

• Entrez ID: 407007
• Gene name: MicroRNA 222
• Gene symbol: MIR222
• Synonyms (NCBI Gene): MIRN222, miRNA222, mir-222
• Chromosome: X
• Chromosome location: Xp11.3
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005615	Component	Extracellular space	HDA	18766170, 26646931
GO:0010634	Process	Positive regulation of epithelial cell migration	IGI	21673316
GO:0010718	Process	Positive regulation of epithelial to mesenchymal transition	IGI	21673316
GO:0016442	Component	RISC complex	IEA
GO:0016525	Process	Negative regulation of angiogenesis	IDA	20489169
GO:0032705	Process	Negative regulation of interleukin-21 production	IDA	28798470
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	16330772, 18413744, 19153141, 19487542, 20299489, 20388878, 20489169, 21711453, 21761362, 22321642, 23770851, 23969726, 24147153, 24736554, 28798470, 29230236
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IGI	21310411, 21673316, 22294051
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IMP	18246122, 20103675, 20813046, 26045994
GO:0043066	Process	Negative regulation of apoptotic process	IDA	20813046
GO:0044828	Process	Host-mediated suppression of viral genome replication	ISS
GO:0045648	Process	Positive regulation of erythrocyte differentiation	IDA	16330772
GO:0048680	Process	Positive regulation of axon regeneration	ISS
GO:0050728	Process	Negative regulation of inflammatory response	IGI	21310411
GO:0060045	Process	Positive regulation of cardiac muscle cell proliferation	ISS
GO:0060354	Process	Negative regulation of cell adhesion molecule production	IGI	21310411
GO:1900016	Process	Negative regulation of cytokine production involved in inflammatory response	ISS
GO:1900087	Process	Positive regulation of G1/S transition of mitotic cell cycle	IDA	18413744
GO:1900149	Process	Positive regulation of Schwann cell migration	ISS
GO:1902034	Process	Negative regulation of hematopoietic stem cell proliferation	IDA	16330772
GO:1903122	Process	Negative regulation of TRAIL-activated apoptotic signaling pathway	IMP	18246122
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	16330772, 18413744, 19153141, 19487542, 20299489, 20388878, 20489169, 21711453, 21761362, 22321642, 23770851, 23969726, 24147153, 24736554, 28798470, 29230236
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IGI	21310411, 21673316, 22294051
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IMP	20103675, 20813046, 26045994
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1903588	Process	Negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	IDA	20489169
GO:1904707	Process	Positive regulation of vascular associated smooth muscle cell proliferation	ISS
GO:1904995	Process	Negative regulation of leukocyte adhesion to vascular endothelial cell	IGI	21310411
GO:1905046	Process	Positive regulation of Schwann cell proliferation involved in axon regeneration	ISS
GO:2000726	Process	Negative regulation of cardiac muscle cell differentiation	ISS

Other IDs

• MIM: 300569
• HGNC: 31602
• e!Ensembl: ENSG00000207725

Interactions View interactions

Pathways

KEGG:

MicroRNAs in cancer