MIR221 (microRNA 221)

Gene
Gene Gene ontology Other IDs Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
407006
Gene name Gene Name - the full gene name approved by the HGNC.
MicroRNA 221
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MIR221
Synonyms (NCBI Gene) Gene synonyms aliases
MIRN221, miRNA221, mir-221
Chromosome Chromosome number
X
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
Xp11.3
Summary Summary of gene provided in NCBI Entrez Gene.
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Pathways Associated diseases
Show/Hide all(48)
GO ID Ontology Definition Evidence Reference
GO:0005615 Component Extracellular space HDA 18766170
GO:0005615 Component Extracellular space HDA 26646931
GO:0006954 Process Inflammatory response IDA 20110463
GO:0008285 Process Negative regulation of cell population proliferation IDA 23333386
GO:0009749 Process Response to glucose IMP 19351599
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Pathways Associated diseases
MIM HGNC e!Ensembl
300568 31601 ENSG00000207870
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene Gene ontology Other IDs Pathways Associated diseases
  KEGG  
  MicroRNAs in cancer  
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene Gene ontology Other IDs Pathways Associated diseases
Show/Hide Unknown Diseases (1)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Prostate cancer Prostate cancer miRNA (miR)?205, miR?221, miR?222, miR?30c, miR?224, miR?455?3p, miR?23b and miR?505 were downregulated in patients with prostate cancer (PCa) and were experimentally validated to function as tumor suppressors in prostate cancer cells, affecting tumor pro 32901864 CBGDA
Show/Hide Text Mining Associations (207)
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Adenocarcinoma Associate 25252191
Adenocarcinoma Follicular Associate 23563786
Adenocarcinoma Mucinous Stimulate 21757972
Alopecia Associate 37496996
Alzheimer Disease Associate 38195609
Amyotrophic Lateral Sclerosis Associate 28870590
Aneurysm Associate 28425970
Aortic Aneurysm Abdominal Associate 28425970
Aortic Aneurysm Thoracic Associate 28425970
Aortic Aneurysm Thoracic Stimulate 35563123