MIR21 (microRNA 21)

Gene
Gene miRNA Gene ontology Other IDs Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
406991
Gene name Gene Name - the full gene name approved by the HGNC.
MicroRNA 21
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MIR21
Synonyms (NCBI Gene) Gene synonyms aliases
MIRN21, hsa-mir-21, miR-21, miRNA21
Chromosome Chromosome number
17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17q23.1
Summary Summary of gene provided in NCBI Entrez Gene.
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Pathways Associated diseases
Show/Hide all(1)
miRTarBase ID miRNA Experiments Reference
MIRT737295 hsa-miR-21-3p qRT-PCR 32637580
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Pathways Associated diseases
Show/Hide all(123)
GO ID Ontology Definition Evidence Reference
GO:0001568 Process Blood vessel development ISS 28270521
GO:0001819 Process Positive regulation of cytokine production IDA 30106099
GO:0001934 Process Positive regulation of protein phosphorylation IDA 16762633
GO:0001934 Process Positive regulation of protein phosphorylation ISS
GO:0001937 Process Negative regulation of endothelial cell proliferation IDA 21347332, 23496142
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Pathways Associated diseases
MIM HGNC e!Ensembl
611020 31586 ENSG00000284190
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Pathways Associated diseases
  KEGG  
  Proteoglycans in cancer
MicroRNAs in cancer 		 
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Pathways Associated diseases
Show/Hide Causal Diseases (5)
Causal
Disease term Disease name dbSNP ID References
Esophagus neoplasm Esophageal Neoplasms, Malignant neoplasm of esophagus rs28934578, rs121918714, rs1567556006, rs1575166666 21248297
Kidney disease Kidney Diseases rs74315342, rs749740335, rs757649673, rs112417755, rs35138315 23469132
Lung cancer Malignant neoplasm of lung rs121913530, rs121913529, rs878855122, rs1057519784, rs770315135 27323401
Obesity Obesity rs74315349, rs1474810899, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562
View all (27 more)		 23954404
Show/Hide Unknown Diseases (2)
Unknown
Disease term Disease name Evidence References Source
Cirrhosis Cirrhosis 23469132 ClinVar
Endometriosis Endometriosis 21063030 ClinVar
Show/Hide Text Mining Associations (515)
Associations from Text Mining
Disease Name Relationship Type References
Acidosis Renal Tubular Associate 24370587
Acute Coronary Syndrome Associate 21804579, 26842377, 31764830, 34944034
Acute Coronary Syndrome Stimulate 32033332
Acute Kidney Injury Associate 23717419, 27122240
Acute Kidney Injury Inhibit 37285824
Acute On Chronic Liver Failure Associate 26267843, 26871786
Adenocarcinoma Stimulate 19789312, 26465597, 29731265
Adenocarcinoma Associate 21102586, 21757972, 22174421, 23466817, 23724052, 24039846, 25928282, 26338526, 27072269, 30531928, 32091667
Adenocarcinoma Mucinous Stimulate 21757972
Adenocarcinoma of Lung Associate 19597153, 21116241, 21351266, 23036707, 26405811, 27081085, 28089356, 29663730, 29806739, 29892003, 30372890, 32091667, 34337857, 35996717, 39334033
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