MIR206 (microRNA 206)

Gene

• Entrez ID: 406989
• Gene name: MicroRNA 206
• Gene symbol: MIR206
• Synonyms (NCBI Gene): MIRN206, miRNA206, mir-206
• Chromosome: 6
• Chromosome location: 6p12.2
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003730	Function	MRNA 3'-UTR binding	IDA	24603323, 26125274, 28342807, 31507089
GO:0005515	Function	Protein binding	IPI	31507089
GO:0010455	Process	Positive regulation of cell fate commitment	ISS
GO:0010628	Process	Positive regulation of gene expression	IDA	24603323
GO:0010629	Process	Negative regulation of gene expression	IDA	28342807
GO:0010831	Process	Positive regulation of myotube differentiation	ISS
GO:0010875	Process	Positive regulation of cholesterol efflux	IMP	24603323
GO:0016442	Component	RISC complex	IEA
GO:0016442	Component	RISC complex	IGI	31507089
GO:0032715	Process	Negative regulation of interleukin-6 production	IDA	31507089
GO:0032731	Process	Positive regulation of interleukin-1 beta production	IDA	27277332
GO:0032760	Process	Positive regulation of tumor necrosis factor production	IDA	27277332
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	20388878, 24603323, 26125274, 26175229, 27277332, 28342807, 31507089
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	23499676
GO:0051055	Process	Negative regulation of lipid biosynthetic process	IGI	23499676
GO:0051898	Process	Negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IMP	26175229
GO:0060354	Process	Negative regulation of cell adhesion molecule production	IDA	28342807
GO:0090051	Process	Negative regulation of cell migration involved in sprouting angiogenesis	IDA	26175229
GO:0090370	Process	Negative regulation of cholesterol efflux	IMP	24603323
GO:0150078	Process	Positive regulation of neuroinflammatory response	IDA	27277332
GO:1902004	Process	Positive regulation of amyloid-beta formation	IDA	27277332
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	20388878, 23499676, 24603323, 26125274, 26175229, 27277332, 28342807, 31507089

Other IDs

• MIM: 611599
• HGNC: 31584
• e!Ensembl: ENSG00000207604

Interactions View interactions

Pathways

KEGG:

MicroRNAs in cancer