Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
406988
Gene name Gene Name - the full gene name approved by the HGNC.
MicroRNA 205
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MIR205
Synonyms (NCBI Gene) Gene synonyms aliases
MIRN205, mir-205
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1q32.2
Summary Summary of gene provided in NCBI Entrez Gene.
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001937 Process Negative regulation of endothelial cell proliferation IMP 23800974
GO:0003730 Function MRNA 3'-UTR binding IDA 22578566, 23800974, 23974361, 25012146
GO:0005615 Component Extracellular space HDA 26646931
GO:0010628 Process Positive regulation of gene expression IDA 23800974
GO:0010629 Process Negative regulation of gene expression IDA 23800974
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
613147 31583 ENSG00000284485
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  MicroRNAs in cancer  
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Prostate cancer Prostate cancer miRNA (miR)?205, miR?221, miR?222, miR?30c, miR?224, miR?455?3p, miR?23b and miR?505 were downregulated in patients with prostate cancer (PCa) and were experimentally validated to function as tumor suppressors in prostate cancer cells, affecting tumor pro 32901864 CBGDA
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Acute Kidney Injury Associate 22859986, 30997877
Adenocarcinoma Inhibit 18242245, 32251457
Adenocarcinoma Associate 22805332, 23466817, 23724052, 24625834, 25695220, 26338526, 26711784, 31360113, 34647653, 37686123
Adenocarcinoma of Lung Associate 22331473, 30021798
Adenoma Oxyphilic Associate 30116406
Adenomatous Polyposis Coli Associate 31391772
Alstrom Syndrome Associate 36506055
Amyotrophic Lateral Sclerosis Associate 37612427
Aortic Aneurysm Abdominal Associate 26781079, 34185955
Ascites Associate 29499737