MIR19A (microRNA 19a)

Gene

• Entrez ID: 406979
• Gene name: MicroRNA 19a
• Gene symbol: MIR19A
• Synonyms (NCBI Gene): C13orf25, MIR17HG, MIRH1, MIRHG1, MIRN19A, hsa-mir-19a, miR-19a, miRNA19A
• Chromosome: 13
• Chromosome location: 13q31.3
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002862	Process	Negative regulation of inflammatory response to antigenic stimulus	IDA	22105995
GO:0003730	Function	MRNA 3'-UTR binding	IDA	24378993
GO:0005615	Component	Extracellular space	HDA	26646931
GO:0010629	Process	Negative regulation of gene expression	IGI	25584808
GO:0010667	Process	Negative regulation of cardiac muscle cell apoptotic process	ISS
GO:0010764	Process	Negative regulation of fibroblast migration	IDA	27098600
GO:0016442	Component	RISC complex	IEA
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	IDA	27098600
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	IGI	29130787
GO:0032715	Process	Negative regulation of interleukin-6 production	IDA	22105995
GO:0032715	Process	Negative regulation of interleukin-6 production	IGI	28078022
GO:0034122	Process	Negative regulation of toll-like receptor signaling pathway	IMP	26041742
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	18728182, 21067317, 21271217, 23271053, 24169826, 24378993, 25785039, 26017478, 26041742, 28078022
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IMP	22105995
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	27098600, 29130787
GO:0042113	Process	B cell activation	IDA	26017478
GO:0043066	Process	Negative regulation of apoptotic process	IMP	21271217
GO:0050728	Process	Negative regulation of inflammatory response	IGI	28078022
GO:0050861	Process	Positive regulation of B cell receptor signaling pathway	IDA	24169826, 26017478
GO:0061051	Process	Positive regulation of cell growth involved in cardiac muscle cell development	IGI	24117217
GO:0062044	Process	Negative regulation of cardiac epithelial to mesenchymal transition	IDA	27098600
GO:0070062	Component	Extracellular exosome	ISS
GO:0071221	Process	Cellular response to bacterial lipopeptide	IDA	22105995
GO:1901202	Process	Negative regulation of extracellular matrix assembly	IDA	27098600
GO:1902176	Process	Negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	ISS
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	18728182, 21067317, 21271217, 23271053, 24169826, 24378993, 25785039, 26041742, 27098600, 28078022, 29130787
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IMP	22105995
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1903671	Process	Negative regulation of sprouting angiogenesis	IDA	20299512
GO:1903779	Process	Regulation of cardiac conduction	IDA	23271053
GO:1903845	Process	Negative regulation of cellular response to transforming growth factor beta stimulus	IDA	27098600
GO:1904465	Process	Negative regulation of matrix metallopeptidase secretion	IDA	22105995
GO:1904465	Process	Negative regulation of matrix metallopeptidase secretion	IGI	28078022

Other IDs

• MIM: 609418
• HGNC: 31574
• e!Ensembl: ENSG00000284204

Interactions View interactions

Pathways

KEGG:

MicroRNAs in cancer