MIR195 (microRNA 195)

Gene

• Entrez ID: 406971
• Gene name: MicroRNA 195
• Gene symbol: MIR195
• Synonyms (NCBI Gene): MIRN195, miRNA195, mir-195
• Chromosome: 17
• Chromosome location: 17p13.1
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002931	Process	Response to ischemia	ISS	30497184
GO:0003245	Process	Cardiac muscle tissue growth involved in heart morphogenesis	ISS
GO:0003300	Process	Cardiac muscle hypertrophy	ISS
GO:0003730	Function	MRNA 3'-UTR binding	IDA	25240198, 26440600
GO:0008285	Process	Negative regulation of cell population proliferation	IDA	24294368
GO:0010666	Process	Positive regulation of cardiac muscle cell apoptotic process	ISS
GO:0010715	Process	Regulation of extracellular matrix disassembly	ISS	25201911
GO:0010972	Process	Negative regulation of G2/M transition of mitotic cell cycle	ISS
GO:0016442	Component	RISC complex	IEA
GO:0030514	Process	Negative regulation of BMP signaling pathway	IDA	31921616
GO:0032691	Process	Negative regulation of interleukin-1 beta production	ISS	30497184
GO:0032715	Process	Negative regulation of interleukin-6 production	ISS	30497184
GO:0032720	Process	Negative regulation of tumor necrosis factor production	ISS	30497184
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	HDA	18320040
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	23487264, 24294368, 25240198, 26440600, 26823724, 29665645, 30497184
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	31921616
GO:0043065	Process	Positive regulation of apoptotic process	IDA	24294368
GO:0043124	Process	Negative regulation of canonical NF-kappaB signal transduction	IDA	23487264
GO:0045719	Process	Negative regulation of glycogen biosynthetic process	IMP	25240198
GO:0045930	Process	Negative regulation of mitotic cell cycle	ISS
GO:0046627	Process	Negative regulation of insulin receptor signaling pathway	IMP	25240198
GO:0060392	Process	Negative regulation of SMAD protein signal transduction	IDA	31921616
GO:0061049	Process	Cell growth involved in cardiac muscle cell development	ISS
GO:0090272	Process	Negative regulation of fibroblast growth factor production	IMP	26823724
GO:0106222	Function	LncRNA binding	IDA	31921616
GO:0150079	Process	Negative regulation of neuroinflammatory response	ISS	30497184
GO:1900077	Process	Negative regulation of cellular response to insulin stimulus	IMP	25240198
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	24294368, 25240198, 26440600, 26823724, 29665645, 30497184, 31921616
GO:1903377	Process	Negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	ISS	30497184
GO:1904046	Process	Negative regulation of vascular endothelial growth factor production	HMP	18320040
GO:1904046	Process	Negative regulation of vascular endothelial growth factor production	IMP	26823724
GO:1905205	Process	Positive regulation of connective tissue replacement	ISS
GO:2000752	Process	Regulation of glucosylceramide catabolic process	IGI	25584808

Other IDs

• MIM: 610718
• HGNC: 31566
• e!Ensembl: ENSG00000284112

Interactions View interactions

Pathways

KEGG:

MicroRNAs in cancer