MIR181C (microRNA 181c)

Gene

• Entrez ID: 406957
• Gene name: MicroRNA 181c
• Gene symbol: MIR181C
• Synonyms (NCBI Gene): MIRN181C, mir-181c
• Chromosome: 19
• Chromosome location: 19p13.12
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001774	Process	Microglial cell activation	ISS
GO:0003727	Function	Single-stranded RNA binding	IDA	28379604
GO:0005615	Component	Extracellular space	HDA	26646931
GO:0016442	Component	RISC complex	IEA
GO:0031047	Process	Regulatory ncRNA-mediated gene silencing	IDA	28379604
GO:0032690	Process	Negative regulation of interleukin-1 alpha production	ISS	31172560
GO:0032700	Process	Negative regulation of interleukin-17 production	IDA	25962782
GO:0032703	Process	Negative regulation of interleukin-2 production	IDA	21112091
GO:0032716	Process	Negative regulation of interleukin-7 production	IDA	25962782
GO:0032716	Process	Negative regulation of interleukin-7 production	IDA	25962782
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	25962782, 28379604, 31172560
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IDA	21112091
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	25535255
GO:0043524	Process	Negative regulation of neuron apoptotic process	ISS
GO:0046007	Process	Negative regulation of activated T cell proliferation	IDA	21112091
GO:0050728	Process	Negative regulation of inflammatory response	IMP	28379604
GO:0050728	Process	Negative regulation of inflammatory response	ISS
GO:0050868	Process	Negative regulation of T cell activation	IDA	21112091
GO:0061889	Process	Negative regulation of astrocyte activation	ISS
GO:1901646	Process	Negative regulation of synoviocyte proliferation	IDA	28379604
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	21112091, 25535255, 25962782, 28379604, 31172560

Other IDs

• MIM: 612746
• HGNC: 31552
• e!Ensembl: ENSG00000207613

Interactions View interactions

Pathways

KEGG:

MicroRNAs in cancer